JP2014516964A5 - - Google Patents
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- Publication number
- JP2014516964A5 JP2014516964A5 JP2014511445A JP2014511445A JP2014516964A5 JP 2014516964 A5 JP2014516964 A5 JP 2014516964A5 JP 2014511445 A JP2014511445 A JP 2014511445A JP 2014511445 A JP2014511445 A JP 2014511445A JP 2014516964 A5 JP2014516964 A5 JP 2014516964A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- cdr
- inhibitor
- composition
- irinotecan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CCC*C=C(CC1C(C*CCC=C(C)CC(CC(CN)=O)(C2)C2N=O)*C1)CC=CC Chemical compound CCC*C=C(CC1C(C*CCC=C(C)CC(CC(CN)=O)(C2)C2N=O)*C1)CC=CC 0.000 description 7
- KVZYFDXIXBIWQP-MYVCOICNSA-N CC1(CC1)OC(N[C@@H](c1cnc[n]1C)C(c1c([C@]2(C)N(CC3)CCN3C(OC3(C)CC3)=O)ccc(Cl)c1)=Cc1c2nccc1)=O Chemical compound CC1(CC1)OC(N[C@@H](c1cnc[n]1C)C(c1c([C@]2(C)N(CC3)CCN3C(OC3(C)CC3)=O)ccc(Cl)c1)=Cc1c2nccc1)=O KVZYFDXIXBIWQP-MYVCOICNSA-N 0.000 description 1
- WCWHWFCXLWYCJO-UHFFFAOYSA-N OOC(CCCCCCC(Cc1cc(OCC2=CCCCC2)ccc1)=O)=O Chemical compound OOC(CCCCCCC(Cc1cc(OCC2=CCCCC2)ccc1)=O)=O WCWHWFCXLWYCJO-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161487452P | 2011-05-18 | 2011-05-18 | |
| US61/487,452 | 2011-05-18 | ||
| PCT/US2012/037864 WO2012158657A1 (en) | 2011-05-18 | 2012-05-15 | Therapeutic anti-igf1r combinations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014516964A JP2014516964A (ja) | 2014-07-17 |
| JP2014516964A5 true JP2014516964A5 (https=) | 2015-07-16 |
Family
ID=47177305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014511445A Withdrawn JP2014516964A (ja) | 2011-05-18 | 2012-05-15 | 治療用抗ｉｇｆ１ｒ合剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140079665A1 (https=) |
| EP (1) | EP2709661A4 (https=) |
| JP (1) | JP2014516964A (https=) |
| AU (1) | AU2012255920A1 (https=) |
| CA (1) | CA2834566A1 (https=) |
| WO (1) | WO2012158657A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150297613A1 (en) * | 2011-12-13 | 2015-10-22 | Servicio Andaluz De Salud | Use of agents that alter the peritumoral environment for the treatment of cancer |
| ES2541870B1 (es) | 2013-12-27 | 2016-05-12 | Servicio Andaluz De Salud | Uso de antagonistas no peptídicos de NK1 en una determinada dosis para el tratamiento del cáncer |
| KR102053507B1 (ko) * | 2014-06-02 | 2019-12-06 | 내셔널 양밍 유니버시티 | 약물 내성 암을 치료하는 방법 |
| ES2909576T3 (es) | 2016-10-11 | 2022-05-09 | Univ Duke | Tratamiento con lasofoxifeno del cáncer de mama ER+ |
| US20180221476A1 (en) * | 2017-02-06 | 2018-08-09 | Oncoquest Nc. | Treatment of cancer with therapeutic monoclonal antibody specific for a tumor associated antigen and an immune adjuvant |
| US11497730B2 (en) | 2018-04-10 | 2022-11-15 | Duke University | Lasofoxifene treatment of breast cancer |
| US20220267450A1 (en) | 2020-10-14 | 2022-08-25 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| EP4384219A4 (en) | 2021-08-10 | 2025-06-18 | Viridian Therapeutics, Inc. | COMPOSITIONS, DOSAGES AND METHODS FOR THE TREATMENT OF THYROID EYE DISEASE |
| GB202116903D0 (en) | 2021-11-18 | 2022-01-05 | Sermonix Pharmaceuticals Inc | Lasofoxifene treatment of aromatase-resistant er+ cancer |
| IL318499A (en) | 2022-07-30 | 2025-03-01 | Pinetree Therapeutics Inc | Compounds for targeted lysosomal degradation and methods of using them |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100226884A1 (en) * | 2009-01-20 | 2010-09-09 | Immunomedics, Inc. | Novel Class of Monospecific and Bispecific Humanized Antibodies that Target the Insulin-like Growth Factor Type I Receptor (IGF-1R) |
| WO2011057064A1 (en) * | 2009-11-05 | 2011-05-12 | Brian Long | Igf1r inhibitor based treatment of prostate cancer |
| US20130287763A1 (en) * | 2010-07-28 | 2013-10-31 | Merck Sharp & Dohme Corp. | Combination therapy for treating cancer comprising an igf-1r inhibitor and an akt inhibitor |
-
2012
- 2012-05-15 AU AU2012255920A patent/AU2012255920A1/en not_active Abandoned
- 2012-05-15 US US14/118,007 patent/US20140079665A1/en not_active Abandoned
- 2012-05-15 EP EP12786546.7A patent/EP2709661A4/en not_active Withdrawn
- 2012-05-15 CA CA2834566A patent/CA2834566A1/en not_active Abandoned
- 2012-05-15 WO PCT/US2012/037864 patent/WO2012158657A1/en not_active Ceased
- 2012-05-15 JP JP2014511445A patent/JP2014516964A/ja not_active Withdrawn
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