JP2012247438A5 - - Google Patents
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- Publication number
- JP2012247438A5 JP2012247438A5 JP2012198693A JP2012198693A JP2012247438A5 JP 2012247438 A5 JP2012247438 A5 JP 2012247438A5 JP 2012198693 A JP2012198693 A JP 2012198693A JP 2012198693 A JP2012198693 A JP 2012198693A JP 2012247438 A5 JP2012247438 A5 JP 2012247438A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- cancer
- leukemia
- igfbp2
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81800406P | 2006-06-30 | 2006-06-30 | |
| US60/818,004 | 2006-06-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Division JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012247438A JP2012247438A (ja) | 2012-12-13 |
| JP2012247438A5 true JP2012247438A5 (enExample) | 2013-03-28 |
| JP5816147B2 JP5816147B2 (ja) | 2015-11-18 |
Family
ID=38783580
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Active JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
| JP2012198693A Active JP5816147B2 (ja) | 2006-06-30 | 2012-09-10 | Igfbp2インヒビター |
| JP2013024276A Pending JP2013127473A (ja) | 2006-06-30 | 2013-02-12 | Igfbp2インヒビター |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Active JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013024276A Pending JP2013127473A (ja) | 2006-06-30 | 2013-02-12 | Igfbp2インヒビター |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20080112888A1 (enExample) |
| EP (2) | EP2405270B1 (enExample) |
| JP (3) | JP5399900B2 (enExample) |
| AT (1) | ATE537450T1 (enExample) |
| CA (1) | CA2655997A1 (enExample) |
| ES (1) | ES2427924T3 (enExample) |
| WO (1) | WO2008005469A2 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04011624A (es) | 2002-05-24 | 2005-03-07 | Schering Corp | Anticuerpo neutralizante humano anti-igfr. |
| AR046639A1 (es) * | 2003-11-21 | 2005-12-14 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti- igfr1 |
| EP2281841A3 (en) * | 2004-12-03 | 2013-10-23 | Merck Sharp & Dohme Corp. | Biomarkers for pre-selection of patients for anti-IGF1R therapy |
| NZ556673A (en) | 2005-02-03 | 2010-03-26 | Gen Hospital Corp | Method for treating gefitinib and/or erlotinib resistant cancer with an EGFR inhibitor |
| CN101222926B (zh) * | 2005-04-15 | 2013-07-17 | 默沙东公司 | 用于治疗或预防癌症的方法和组合物 |
| EP3488866A1 (en) | 2005-11-04 | 2019-05-29 | Wyeth LLC | Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272 |
| WO2008005469A2 (en) † | 2006-06-30 | 2008-01-10 | Schering Corporation | Igfbp2 biomarker |
| WO2008057329A2 (en) * | 2006-11-01 | 2008-05-15 | George Mason Intellectual Properties, Inc. Of Fairfax, Virginia | Method for detecting and controlling cancer |
| PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| EP2247757A2 (en) * | 2007-12-18 | 2010-11-10 | Schering Corporation | Biomarkers for sensitivity to anti-igf1r therapy |
| MX2010010480A (es) * | 2008-03-25 | 2010-10-15 | Schering Corp | Metodos de tratamiento o prevencion del cancer colorrectal. |
| EP2282769A4 (en) * | 2008-04-29 | 2012-04-25 | Abbott Lab | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES |
| EP2297209A4 (en) * | 2008-06-03 | 2012-08-01 | Abbott Lab | IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF |
| KR20110016959A (ko) * | 2008-06-03 | 2011-02-18 | 아보트 러보러터리즈 | 이원 가변 도메인 면역글로불린 및 이의 용도 |
| ES2531322T3 (es) | 2008-06-17 | 2015-03-13 | Wyeth Llc | Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina |
| WO2009154645A1 (en) * | 2008-06-20 | 2009-12-23 | Smithkline Beecham Corporation | Methods for the treatment of central nervous system tumors |
| US8822645B2 (en) * | 2008-07-08 | 2014-09-02 | Abbvie Inc. | Prostaglandin E2 dual variable domain immunoglobulins and uses thereof |
| EP3175853B1 (en) | 2008-08-04 | 2023-11-01 | Wyeth LLC | Antineoplastic combinations of neratinib and capecitabine |
| UY32317A (es) | 2008-12-12 | 2010-07-30 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
| AU2010232729A1 (en) | 2009-03-31 | 2011-10-20 | Arqule, Inc. | Substituted indolo-pyridinone compounds |
| PT3000467T (pt) | 2009-04-06 | 2023-03-30 | Wyeth Llc | Regime de tratamento utilizando neratinib para o cancro de mama |
| BRPI1012195A2 (en) * | 2009-05-01 | 2018-04-24 | Abbott Laboratories | double variable domain immunoglobulins and their uses |
| TW201109438A (en) * | 2009-07-29 | 2011-03-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| AR078651A1 (es) * | 2009-10-15 | 2011-11-23 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| WO2011133636A1 (en) | 2010-04-20 | 2011-10-27 | Cedars-Sinai Medical Center | COMBINATION THERAPY WITH CD4 LYMPHOCYTE DEPLETION AND mTOR INHIBITORS |
| US8741288B2 (en) * | 2010-07-07 | 2014-06-03 | Chang Gung Medical Foundation, Linkou Branch | Protein markers for detecting liver cancer and method for identifying the markers thereof |
| PT2829881T (pt) | 2010-07-14 | 2017-11-29 | Commw Scient Ind Res Org | Diagnóstico para cancro colo-rectal |
| KR20130100118A (ko) | 2010-08-03 | 2013-09-09 | 아비에 인코포레이티드 | 이원 가변 도메인 면역글로불린 및 이의 용도 |
| WO2012019031A2 (en) * | 2010-08-04 | 2012-02-09 | Ohio University | Biomarkers for growth hormone disorders |
| US9046513B2 (en) | 2010-08-26 | 2015-06-02 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
| US20130338033A1 (en) * | 2011-01-27 | 2013-12-19 | Virginia Commonwealth University | Diagnostic and Prognostic Markers for Metastasis |
| WO2012106556A2 (en) | 2011-02-02 | 2012-08-09 | Amgen Inc. | Methods and compositons relating to inhibition of igf-1r |
| WO2012116040A1 (en) | 2011-02-22 | 2012-08-30 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma |
| JP2014519813A (ja) | 2011-04-25 | 2014-08-21 | オーエスアイ・ファーマシューティカルズ,エルエルシー | 癌薬剤発見、診断、および治療におけるemt遺伝子シグネチャーの使用 |
| UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| AR089529A1 (es) | 2011-12-30 | 2014-08-27 | Abbvie Inc | Proteinas de union especificas duales dirigidas contra il-13 y/o il-17 |
| CN102703502A (zh) * | 2012-02-27 | 2012-10-03 | 同昕生物技术(北京)有限公司 | Rta蛋白的制备方法及其在鼻咽癌检测试剂中的应用 |
| CN110133300B (zh) * | 2012-03-18 | 2022-02-25 | 镜株式会社 | 疾病样品分析装置、分析系统及分析方法 |
| SI2883057T1 (sl) * | 2012-08-09 | 2019-07-31 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Diagnostika srčnega popuščanja |
| PE20151179A1 (es) | 2012-11-01 | 2015-09-12 | Abbvie Inc | Inmunoglobulinas de dominio variable dual anti-vegf/dll4 y usos de las mismas |
| CN104994877A (zh) | 2012-11-02 | 2015-10-21 | 利普生物药剂公司 | 用于癌症治疗的反式-克罗米芬 |
| US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
| AU2014227732A1 (en) | 2013-03-15 | 2015-09-17 | Abbvie Inc. | Dual specific binding proteins directed against IL-1 beta and IL-17 |
| ES2725906T3 (es) | 2013-06-06 | 2019-09-30 | Inst Nat Sante Rech Med | Biomarcador de rehospitalización tras insuficiencia cardíaca |
| US11213583B2 (en) | 2014-02-05 | 2022-01-04 | Cedars-Sinai Medical Center | Methods and compositions for treating cancer and infectious diseases |
| US10093733B2 (en) | 2014-12-11 | 2018-10-09 | Abbvie Inc. | LRP-8 binding dual variable domain immunoglobulin proteins |
| TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
| CA3195512A1 (en) | 2020-10-14 | 2022-04-21 | Vahe Bedian | Compositions and methods for treatment of thyroid eye disease |
| JP2024531151A (ja) | 2021-08-10 | 2024-08-29 | ビリジアン セラピューティクス, インコーポレイテッド | 甲状腺眼疾患の処置のための組成物、用量および方法 |
| CN122122186A (zh) * | 2023-09-06 | 2026-05-29 | 维里迪安治疗公司 | 抗igf-1r抗体的药物组合物 |
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| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
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| US7538195B2 (en) | 2002-06-14 | 2009-05-26 | Immunogen Inc. | Anti-IGF-I receptor antibody |
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| KR20050109489A (ko) | 2003-02-13 | 2005-11-21 | 화이자 프로덕츠 인크. | 항-인슐린양 성장인자 i 수용체 항체의 용도 |
| BRPI0408317A (pt) | 2003-03-14 | 2006-03-07 | Pharmacia Corp | anticorpos do receptor de igf-i para o tratamento de cáncer |
| CA2519113C (en) | 2003-04-02 | 2012-06-05 | F. Hoffmann-La Roche Ag | Antibodies against insulin-like growth factor i receptor and uses thereof |
| EP2365001A3 (en) | 2003-05-01 | 2012-03-28 | Imclone LLC | Fully human antibodies directed against the human insulin-like growth factor-1 receptor |
| CA2527285A1 (en) * | 2003-05-28 | 2004-12-23 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| EP1694850B1 (en) * | 2003-11-12 | 2011-06-29 | Schering Corporation | Plasmid system for multigene expression |
| AR046639A1 (es) * | 2003-11-21 | 2005-12-14 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti- igfr1 |
| EP2281841A3 (en) * | 2004-12-03 | 2013-10-23 | Merck Sharp & Dohme Corp. | Biomarkers for pre-selection of patients for anti-IGF1R therapy |
| CN101222926B (zh) * | 2005-04-15 | 2013-07-17 | 默沙东公司 | 用于治疗或预防癌症的方法和组合物 |
| BRPI0611800A2 (pt) * | 2005-06-15 | 2008-12-09 | Schering Corp | formulaÇço estÁvel de anticorpo |
| WO2008005469A2 (en) † | 2006-06-30 | 2008-01-10 | Schering Corporation | Igfbp2 biomarker |
| EP2145021A2 (en) * | 2007-05-17 | 2010-01-20 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to insulin growth factor-1 receptor modulators |
-
2007
- 2007-06-29 WO PCT/US2007/015423 patent/WO2008005469A2/en not_active Ceased
- 2007-06-29 EP EP11162598.4A patent/EP2405270B1/en not_active Revoked
- 2007-06-29 EP EP07810179.7A patent/EP2032989B2/en active Active
- 2007-06-29 AT AT07810179T patent/ATE537450T1/de active
- 2007-06-29 US US11/771,454 patent/US20080112888A1/en not_active Abandoned
- 2007-06-29 CA CA002655997A patent/CA2655997A1/en active Pending
- 2007-06-29 JP JP2009518353A patent/JP5399900B2/ja active Active
- 2007-06-29 ES ES11162598T patent/ES2427924T3/es active Active
-
2012
- 2012-09-10 JP JP2012198693A patent/JP5816147B2/ja active Active
-
2013
- 2013-02-12 JP JP2013024276A patent/JP2013127473A/ja active Pending
-
2014
- 2014-12-01 US US14/556,402 patent/US20150168424A1/en not_active Abandoned
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