JP2012247438A5 - - Google Patents
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- Publication number
- JP2012247438A5 JP2012247438A5 JP2012198693A JP2012198693A JP2012247438A5 JP 2012247438 A5 JP2012247438 A5 JP 2012247438A5 JP 2012198693 A JP2012198693 A JP 2012198693A JP 2012198693 A JP2012198693 A JP 2012198693A JP 2012247438 A5 JP2012247438 A5 JP 2012247438A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- cancer
- leukemia
- igfbp2
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81800406P | 2006-06-30 | 2006-06-30 | |
| US60/818,004 | 2006-06-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Division JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012247438A JP2012247438A (ja) | 2012-12-13 |
| JP2012247438A5 true JP2012247438A5 (enExample) | 2013-03-28 |
| JP5816147B2 JP5816147B2 (ja) | 2015-11-18 |
Family
ID=38783580
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Active JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
| JP2012198693A Active JP5816147B2 (ja) | 2006-06-30 | 2012-09-10 | Igfbp2インヒビター |
| JP2013024276A Pending JP2013127473A (ja) | 2006-06-30 | 2013-02-12 | Igfbp2インヒビター |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Active JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013024276A Pending JP2013127473A (ja) | 2006-06-30 | 2013-02-12 | Igfbp2インヒビター |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20080112888A1 (enExample) |
| EP (2) | EP2032989B2 (enExample) |
| JP (3) | JP5399900B2 (enExample) |
| AT (1) | ATE537450T1 (enExample) |
| CA (1) | CA2655997A1 (enExample) |
| ES (1) | ES2427924T3 (enExample) |
| WO (1) | WO2008005469A2 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ536475A (en) * | 2002-05-24 | 2008-06-30 | Schering Corp | Neutralizing human anti-igfr antibody |
| PE20050928A1 (es) * | 2003-11-21 | 2005-11-08 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti-igfr1 |
| DE602005025685D1 (de) * | 2004-12-03 | 2011-02-10 | Schering Corp | Biologische marker zur vorauswahl von patienten für die anti-igf1r-therapie |
| CN108421044A (zh) | 2005-02-03 | 2018-08-21 | 综合医院公司 | 治疗吉非替尼耐药性癌症的方法 |
| US20060233810A1 (en) * | 2005-04-15 | 2006-10-19 | Yaolin Wang | Methods and compositions for treating or preventing cancer |
| BRPI0618042A2 (pt) | 2005-11-04 | 2011-08-16 | Wyeth Corp | usos de uma rapamicina e de uma herceptina, produto, pacote farmacêutico, e, composição farmacêutica |
| US20080112888A1 (en) † | 2006-06-30 | 2008-05-15 | Schering Corporation | Igfbp2 biomarker |
| EP2089055A4 (en) * | 2006-11-01 | 2011-02-02 | George Mason Intellectual Prop | METHOD FOR THE DETECTION AND CONTROL OF CANCER |
| PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| EP2247757A2 (en) * | 2007-12-18 | 2010-11-10 | Schering Corporation | Biomarkers for sensitivity to anti-igf1r therapy |
| EP2259797A2 (en) * | 2008-03-25 | 2010-12-15 | Schering Corporation | Methods for treating or preventing colorectal cancer |
| JP5646457B2 (ja) * | 2008-04-29 | 2014-12-24 | アッヴィ・インコーポレイテッド | 二重可変ドメイン免疫グロブリン及びその使用 |
| EP3002299A1 (en) * | 2008-06-03 | 2016-04-06 | AbbVie Inc. | Dual variable domain immunoglobulins and uses thereof |
| PE20100054A1 (es) * | 2008-06-03 | 2010-03-03 | Abbott Lab | Inmunoglobulina con dominio variable dual |
| CN102641270A (zh) | 2008-06-17 | 2012-08-22 | 惠氏有限责任公司 | 含有hki-272和长春瑞滨的抗肿瘤组合 |
| WO2009154645A1 (en) * | 2008-06-20 | 2009-12-23 | Smithkline Beecham Corporation | Methods for the treatment of central nervous system tumors |
| MX2010014574A (es) * | 2008-07-08 | 2011-04-27 | Abbott Lab | Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas. |
| US8669273B2 (en) | 2008-08-04 | 2014-03-11 | Wyeth Llc | Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine |
| EP2376116B1 (en) | 2008-12-12 | 2015-12-09 | Boehringer Ingelheim International GmbH | Anti-igf antibodies |
| US8410144B2 (en) | 2009-03-31 | 2013-04-02 | Arqule, Inc. | Substituted indolo-pyridinone compounds |
| IL264349B2 (en) | 2009-04-06 | 2024-01-01 | Wyeth Llc | Regimen comprising neratinib for the treatment of cancer |
| MX2011011670A (es) * | 2009-05-01 | 2011-11-18 | Abbott Lab | Inmunoglobulinas de dominio variable dual y usos de las mismas. |
| TW201109438A (en) * | 2009-07-29 | 2011-03-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| MX2012004415A (es) * | 2009-10-15 | 2012-05-08 | Abbott Lab | Inmunoglobulinas de dominio variable doble y usos de las mismas. |
| UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| WO2011133636A1 (en) * | 2010-04-20 | 2011-10-27 | Cedars-Sinai Medical Center | COMBINATION THERAPY WITH CD4 LYMPHOCYTE DEPLETION AND mTOR INHIBITORS |
| US8741288B2 (en) * | 2010-07-07 | 2014-06-03 | Chang Gung Medical Foundation, Linkou Branch | Protein markers for detecting liver cancer and method for identifying the markers thereof |
| US20130345322A1 (en) * | 2010-07-14 | 2013-12-26 | Commonwealth Scientific And Industrial Research Organisation | Diagnostic for colorectal cancer |
| US8735546B2 (en) | 2010-08-03 | 2014-05-27 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
| WO2012019031A2 (en) * | 2010-08-04 | 2012-02-09 | Ohio University | Biomarkers for growth hormone disorders |
| PH12013500337A1 (en) | 2010-08-26 | 2017-08-23 | Abbvie Inc | Dual variable domain immunoglobulins and uses thereof |
| US20130338033A1 (en) * | 2011-01-27 | 2013-12-19 | Virginia Commonwealth University | Diagnostic and Prognostic Markers for Metastasis |
| AU2012212075A1 (en) | 2011-02-02 | 2013-07-18 | Amgen Inc. | Methods and compositons relating to inhibition of IGF-1R |
| WO2012116040A1 (en) | 2011-02-22 | 2012-08-30 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma |
| JP2014519813A (ja) | 2011-04-25 | 2014-08-21 | オーエスアイ・ファーマシューティカルズ,エルエルシー | 癌薬剤発見、診断、および治療におけるemt遺伝子シグネチャーの使用 |
| UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| US9120870B2 (en) | 2011-12-30 | 2015-09-01 | Abbvie Inc. | Dual specific binding proteins directed against IL-13 and IL-17 |
| CN102703502A (zh) * | 2012-02-27 | 2012-10-03 | 同昕生物技术(北京)有限公司 | Rta蛋白的制备方法及其在鼻咽癌检测试剂中的应用 |
| US20150079623A1 (en) * | 2012-03-18 | 2015-03-19 | Kyushu University, National University Corporation | Apparatus, system and method for analyzing disease sample |
| EP2883057B1 (en) * | 2012-08-09 | 2018-12-05 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Diagnostic of heart failure |
| AU2013337775B2 (en) | 2012-11-01 | 2017-03-30 | Abbvie Inc. | Anti-VEGF/DLL4 dual variable domain immunoglobulins and uses thereof |
| WO2014070523A1 (en) * | 2012-11-02 | 2014-05-08 | Repros Therapeutics Inc. | Trans-clomiphene for use in cancer therapy |
| US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
| EP2970459A2 (en) | 2013-03-15 | 2016-01-20 | AbbVie Inc. | Dual specific binding proteins directed against il-1beta and il-17 |
| PT3004891T (pt) | 2013-06-06 | 2019-05-30 | Inst Nat Sante Rech Med | Biomarcador de re-hospitalização após uma insuficiência cardíaca |
| WO2015120198A1 (en) | 2014-02-05 | 2015-08-13 | Cedars-Sinai Medical Center | Methods and compositions for treating cancer and infectious diseases |
| US10093733B2 (en) | 2014-12-11 | 2018-10-09 | Abbvie Inc. | LRP-8 binding dual variable domain immunoglobulin proteins |
| TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
| TW202228775A (zh) | 2020-10-14 | 2022-08-01 | 美商維里迪恩醫療股份有限公司 | 用於治療甲狀腺眼病之組合物及方法 |
| TW202320850A (zh) | 2021-08-10 | 2023-06-01 | 美商維里迪恩醫療股份有限公司 | 用於治療甲狀腺眼病之組合物、劑量及方法 |
| IL326876A (en) * | 2023-09-06 | 2026-04-01 | Viridian Therapeutics Inc | Pharmaceutical preparations of anti-IGF-1R antibodies |
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| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
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| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
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| FR2834900B1 (fr) | 2002-01-18 | 2005-07-01 | Pf Medicament | Nouvelles compositions a activite anti-igf-ir et anti-egfr et leurs applications |
| FR2834990A1 (fr) | 2002-01-18 | 2003-07-25 | Pf Medicament | Nouveaux anticorps anti-igf-ir et leurs applications |
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| TW200401638A (en) | 2002-06-20 | 2004-02-01 | Bristol Myers Squibb Co | Heterocyclic inhibitors of kinases |
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| CA2514231A1 (en) | 2003-02-13 | 2004-08-26 | Pfizer Products Inc. | Uses of anti-insulin-like growth factor i receptor antibodies |
| MXPA05009837A (es) | 2003-03-14 | 2005-12-05 | Pharmacia Corp | Anticuerpos para el receptor del factor de crecimiento tipo insulina-i, para el tratamiento de canceres. |
| ES2383014T3 (es) | 2003-04-02 | 2012-06-15 | F. Hoffmann-La Roche Ag | Anticuerpos contra el factor I de crecimiento similar a insulina y usos de los mismos |
| CA2524305C (en) | 2003-05-01 | 2015-12-08 | Imclone Systems Incorporated | Fully human antibodies directed against the human insulin-like growth factor-1 receptor |
| EP1631689A2 (en) * | 2003-05-28 | 2006-03-08 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| ATE514783T1 (de) | 2003-11-12 | 2011-07-15 | Schering Corp | Plasmidsystem zur expression mehrerer gene |
| PE20050928A1 (es) * | 2003-11-21 | 2005-11-08 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti-igfr1 |
| DE602005025685D1 (de) * | 2004-12-03 | 2011-02-10 | Schering Corp | Biologische marker zur vorauswahl von patienten für die anti-igf1r-therapie |
| US20060233810A1 (en) * | 2005-04-15 | 2006-10-19 | Yaolin Wang | Methods and compositions for treating or preventing cancer |
| AU2006259536A1 (en) * | 2005-06-15 | 2006-12-28 | Schering Corporation | Anti-IGF1R antibody formulations |
| US20080112888A1 (en) † | 2006-06-30 | 2008-05-15 | Schering Corporation | Igfbp2 biomarker |
| EP2145021A2 (en) * | 2007-05-17 | 2010-01-20 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to insulin growth factor-1 receptor modulators |
-
2007
- 2007-06-29 US US11/771,454 patent/US20080112888A1/en not_active Abandoned
- 2007-06-29 AT AT07810179T patent/ATE537450T1/de active
- 2007-06-29 CA CA002655997A patent/CA2655997A1/en active Pending
- 2007-06-29 ES ES11162598T patent/ES2427924T3/es active Active
- 2007-06-29 WO PCT/US2007/015423 patent/WO2008005469A2/en not_active Ceased
- 2007-06-29 EP EP07810179.7A patent/EP2032989B2/en active Active
- 2007-06-29 JP JP2009518353A patent/JP5399900B2/ja active Active
- 2007-06-29 EP EP11162598.4A patent/EP2405270B1/en not_active Revoked
-
2012
- 2012-09-10 JP JP2012198693A patent/JP5816147B2/ja active Active
-
2013
- 2013-02-12 JP JP2013024276A patent/JP2013127473A/ja active Pending
-
2014
- 2014-12-01 US US14/556,402 patent/US20150168424A1/en not_active Abandoned
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