BRPI0611800A2 - formulaÇço estÁvel de anticorpo - Google Patents
formulaÇço estÁvel de anticorpoInfo
- Publication number
- BRPI0611800A2 BRPI0611800A2 BRPI0611800-3A BRPI0611800A BRPI0611800A2 BR PI0611800 A2 BRPI0611800 A2 BR PI0611800A2 BR PI0611800 A BRPI0611800 A BR PI0611800A BR PI0611800 A2 BRPI0611800 A2 BR PI0611800A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibody formulation
- stable antibody
- antibody
- formulation
- stable
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dispersion Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
Abstract
FORMULAÇçO ESTÁVEL DE ANTICORPO. A presente invenção fornece uma formulação farmacêutica que compreende um anticorpo ou fragmento de ligação de antígeno desse que exibe alta estabilidade; junto com métodos de uso dessa.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69081005P | 2005-06-15 | 2005-06-15 | |
PCT/US2006/022995 WO2006138315A2 (en) | 2005-06-15 | 2006-06-13 | Anti-igf1r antibody formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0611800A2 true BRPI0611800A2 (pt) | 2008-12-09 |
Family
ID=37571071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0611800-3A BRPI0611800A2 (pt) | 2005-06-15 | 2006-06-13 | formulaÇço estÁvel de anticorpo |
Country Status (16)
Country | Link |
---|---|
US (1) | US20060286103A1 (pt) |
EP (1) | EP1896505A2 (pt) |
JP (2) | JP2008546699A (pt) |
KR (1) | KR20080019249A (pt) |
CN (1) | CN101287761A (pt) |
AR (1) | AR054474A1 (pt) |
AU (1) | AU2006259536A1 (pt) |
BR (1) | BRPI0611800A2 (pt) |
CA (1) | CA2611149A1 (pt) |
MX (1) | MX2007016306A (pt) |
NO (1) | NO20080246L (pt) |
NZ (1) | NZ564098A (pt) |
PE (2) | PE20100096A1 (pt) |
TW (1) | TW200745161A (pt) |
WO (1) | WO2006138315A2 (pt) |
ZA (1) | ZA200710855B (pt) |
Families Citing this family (56)
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US7217796B2 (en) * | 2002-05-24 | 2007-05-15 | Schering Corporation | Neutralizing human anti-IGFR antibody |
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JP2008521907A (ja) * | 2004-12-03 | 2008-06-26 | シェーリング コーポレイション | 抗igf1r治療について患者を予め選択するためのバイオマーカー |
CN101222926B (zh) * | 2005-04-15 | 2013-07-17 | 默沙东公司 | 用于治疗或预防癌症的方法和组合物 |
JP5399900B2 (ja) * | 2006-06-30 | 2014-01-29 | メルク・シャープ・アンド・ドーム・コーポレーション | Igfbp2インヒビター |
EP3345607B1 (en) * | 2006-12-29 | 2022-10-26 | Ossifi-Mab LLC | Methods of altering bone growth by administration of sost or wise antagonist or agonist |
CA2681743A1 (en) * | 2007-03-22 | 2008-09-25 | Imclone Llc | Stable antibody formulations |
US20090181027A1 (en) * | 2007-09-28 | 2009-07-16 | Paul Dal Monte | Anti-IL-12/23p40 Antibodies, Epitopes, Formulations, Compositions, Methods and Uses |
JP2011515478A (ja) * | 2008-03-25 | 2011-05-19 | シェーリング コーポレイション | 結腸直腸がんを処置または予防するための方法 |
JP5931442B2 (ja) * | 2008-08-27 | 2016-06-08 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 操作された抗IL−23p19抗体の凍結乾燥製剤 |
MX2011004998A (es) * | 2008-11-12 | 2011-05-25 | Schering Corp | Intron de beta-globina-inmunoglobina gamma para la expresion mejorada del anti-factor de crecimiento similar a la insulina 1r. |
AU2010279384A1 (en) * | 2009-08-05 | 2012-03-01 | Wake Forest University | Compositions and methods for inducing apoptosis in prostate cancer cells |
WO2011029823A1 (en) | 2009-09-09 | 2011-03-17 | Novartis Ag | Monoclonal antibody reactive with cd63 when expressed at the surface of degranulated mast cells |
EP2552482A2 (en) * | 2010-03-31 | 2013-02-06 | Université de Genève | Stabilized antibody preparations and uses thereof |
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-
2006
- 2006-06-13 AU AU2006259536A patent/AU2006259536A1/en not_active Abandoned
- 2006-06-13 JP JP2008517021A patent/JP2008546699A/ja not_active Ceased
- 2006-06-13 CN CNA2006800285673A patent/CN101287761A/zh active Pending
- 2006-06-13 CA CA002611149A patent/CA2611149A1/en not_active Abandoned
- 2006-06-13 MX MX2007016306A patent/MX2007016306A/es not_active Application Discontinuation
- 2006-06-13 WO PCT/US2006/022995 patent/WO2006138315A2/en active Application Filing
- 2006-06-13 US US11/452,167 patent/US20060286103A1/en not_active Abandoned
- 2006-06-13 KR KR1020077030486A patent/KR20080019249A/ko not_active Application Discontinuation
- 2006-06-13 EP EP06773043A patent/EP1896505A2/en not_active Withdrawn
- 2006-06-13 BR BRPI0611800-3A patent/BRPI0611800A2/pt not_active IP Right Cessation
- 2006-06-13 NZ NZ564098A patent/NZ564098A/en not_active IP Right Cessation
- 2006-06-14 PE PE2009001322A patent/PE20100096A1/es not_active Application Discontinuation
- 2006-06-14 PE PE2006000669A patent/PE20070116A1/es not_active Application Discontinuation
- 2006-06-14 AR ARP060102524A patent/AR054474A1/es not_active Application Discontinuation
- 2006-06-15 TW TW095121416A patent/TW200745161A/zh unknown
-
2007
- 2007-12-13 ZA ZA200710855A patent/ZA200710855B/xx unknown
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2008
- 2008-01-14 NO NO20080246A patent/NO20080246L/no not_active Application Discontinuation
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2011
- 2011-05-06 JP JP2011103850A patent/JP2011148841A/ja not_active Withdrawn
Also Published As
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ZA200710855B (en) | 2008-12-31 |
AR054474A1 (es) | 2007-06-27 |
NZ564098A (en) | 2010-04-30 |
AU2006259536A1 (en) | 2006-12-28 |
KR20080019249A (ko) | 2008-03-03 |
CA2611149A1 (en) | 2006-12-28 |
PE20070116A1 (es) | 2007-02-09 |
MX2007016306A (es) | 2008-03-07 |
WO2006138315A2 (en) | 2006-12-28 |
JP2008546699A (ja) | 2008-12-25 |
PE20100096A1 (es) | 2010-02-17 |
WO2006138315A3 (en) | 2007-06-07 |
CN101287761A (zh) | 2008-10-15 |
TW200745161A (en) | 2007-12-16 |
US20060286103A1 (en) | 2006-12-21 |
EP1896505A2 (en) | 2008-03-12 |
NO20080246L (no) | 2008-03-17 |
JP2011148841A (ja) | 2011-08-04 |
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