|
BE567431A
(enExample)
|
1957-05-07 |
|
|
|
|
US4323581A
(en)
|
1978-07-31 |
1982-04-06 |
Johnson & Johnson |
Method of treating carcinogenesis
|
|
IE52670B1
(en)
|
1981-03-03 |
1988-01-20 |
Leo Ab |
Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
|
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
|
US4806352A
(en)
|
1986-04-15 |
1989-02-21 |
Ribi Immunochem Research Inc. |
Immunological lipid emulsion adjuvant
|
|
DE3768232D1
(de)
|
1986-12-19 |
1991-04-04 |
Duphar Int Res |
Dimethyldioctadecylammoniumbromid enthaltende stabilisierte adjuvanssuspension.
|
|
WO1988007045A1
(fr)
|
1987-03-09 |
1988-09-22 |
Kyowa Hakko Kogyo Co., Ltd. |
Derives de la substance physiologiquement active k-252
|
|
EP0283085B1
(en)
|
1987-03-17 |
1992-11-11 |
Akzo N.V. |
Adjuvant mixture
|
|
WO1989007105A1
(fr)
|
1988-02-04 |
1989-08-10 |
Kyowa Hakko Kogyo Co., Ltd. |
Derives de staurosporine
|
|
NZ227850A
(en)
|
1988-02-10 |
1991-11-26 |
Hoffmann La Roche |
Indole substituted pyrrole derivatives; preparatory process and medicaments for use against inflammatory immunological, bronchopulmonary or vascular disorders
|
|
DE3841091A1
(de)
|
1988-12-07 |
1990-06-13 |
Behringwerke Ag |
Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung
|
|
US5238944A
(en)
|
1988-12-15 |
1993-08-24 |
Riker Laboratories, Inc. |
Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
|
|
DE68907045T2
(de)
|
1989-01-17 |
1993-12-02 |
Eniricerche Spa |
Synthetische Peptide und deren Verwendung als allgemeine Träger für die Herstellung von immunogenischen Konjugaten, die für die Entwicklung von synthetischen Impfstoffen geeignet sind.
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
CA2011896C
(en)
|
1989-04-21 |
2001-05-08 |
Mark Werner |
Ringworm vaccine
|
|
WO1990014357A1
(en)
|
1989-05-19 |
1990-11-29 |
Genentech, Inc. |
Her2 extracellular domain
|
|
CA2017507C
(en)
|
1989-05-25 |
1996-11-12 |
Gary Van Nest |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
AU645760B2
(en)
|
1989-08-04 |
1994-01-27 |
Berlex Laboratories, Inc. |
C-erbb-2 external domain: GP75
|
|
US5439936A
(en)
|
1989-10-03 |
1995-08-08 |
The Regents Of The University Of California |
Method of treating certain tumors using illudin analogs
|
|
IT1237764B
(it)
|
1989-11-10 |
1993-06-17 |
Eniricerche Spa |
Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
|
|
IL98715A0
(en)
|
1990-08-13 |
1992-07-15 |
American Cyanamid Co |
Filamentous hemaglutinin of bodetella pertussis as a carrier molecule for conjugate vaccines
|
|
US5153312A
(en)
|
1990-09-28 |
1992-10-06 |
American Cyanamid Company |
Oligosaccharide conjugate vaccines
|
|
US5284652A
(en)
|
1990-10-26 |
1994-02-08 |
Pier Allan C |
Dermatophyte vaccine
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
US5268376A
(en)
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
WO1993007153A1
(en)
|
1991-10-10 |
1993-04-15 |
Schering Corporation |
4'-(n-substituted-n-oxide)staurosporine derivatives
|
|
US5266575A
(en)
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
|
EP0610433A1
(en)
|
1991-11-08 |
1994-08-17 |
The University Of Southern California |
Compositions containing k-252 compounds for potentiation of neurotrophin activity
|
|
WO1993010814A1
(en)
|
1991-11-29 |
1993-06-10 |
Viagene, Inc. |
Anti-cancer immunotherapeutic vector constructs
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
DE69334197T2
(de)
|
1992-03-02 |
2008-12-11 |
Novartis Vaccines And Diagnostics S.R.L. |
Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und Diagnostik
|
|
IT1262896B
(it)
|
1992-03-06 |
1996-07-22 |
|
Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
|
|
US5756494A
(en)
|
1992-07-24 |
1998-05-26 |
Cephalon, Inc. |
Protein kinase inhibitors for treatment of neurological disorders
|
|
US5621100A
(en)
|
1992-07-24 |
1997-04-15 |
Cephalon, Inc. |
K-252a derivatives for treatment of neurological disorders
|
|
WO1994006799A1
(en)
|
1992-09-21 |
1994-03-31 |
Kyowa Hakko Kogyo Co., Ltd. |
Thrombocytopenia remedy
|
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
AU681687B2
(en)
|
1993-07-15 |
1997-09-04 |
Minnesota Mining And Manufacturing Company |
Imidazo(4,5-c)pyridin-4-amines
|
|
US5352784A
(en)
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
|
US5624949A
(en)
|
1993-12-07 |
1997-04-29 |
Eli Lilly And Company |
Protein kinase C inhibitors
|
|
EP0817627B1
(en)
|
1993-12-23 |
2005-03-09 |
Eli Lilly And Company |
Protein kinase c inhibitors
|
|
US6083903A
(en)
|
1994-10-28 |
2000-07-04 |
Leukosite, Inc. |
Boronic ester and acid compounds, synthesis and uses
|
|
US5482936A
(en)
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
|
IL117483A
(en)
|
1995-03-17 |
2008-03-20 |
Bernard Brodeur |
MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
|
|
ES2332984T3
(es)
|
1995-03-30 |
2010-02-16 |
Pfizer Products Inc. |
Derivados de quinazolinas.
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US6331555B1
(en)
|
1995-06-01 |
2001-12-18 |
University Of California |
Treatment of platelet derived growth factor related disorders such as cancers
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
GB9513261D0
(en)
|
1995-06-29 |
1995-09-06 |
Smithkline Beecham Biolog |
Vaccines
|
|
US5554519A
(en)
|
1995-08-07 |
1996-09-10 |
Fermalogic, Inc. |
Process of preparing genistein
|
|
AU6888196A
(en)
|
1995-08-11 |
1997-03-12 |
Yale University |
Glycosylated indolocarbazole synthesis
|
|
FR2741881B1
(fr)
|
1995-12-01 |
1999-07-30 |
Centre Nat Rech Scient |
Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
|
|
CN1101392C
(zh)
|
1995-12-08 |
2003-02-12 |
詹森药业有限公司 |
抑制法呢基蛋白质转移酶的(咪唑-5-基)甲基-2-喹啉酮衍生物
|
|
WO1997037026A1
(en)
|
1996-04-02 |
1997-10-09 |
Smithkline Beecham Corporation |
Novel compounds
|
|
US5849733A
(en)
|
1996-05-10 |
1998-12-15 |
Bristol-Myers Squibb Co. |
2-thio or 2-oxo flavopiridol analogs
|
|
EP0934336A1
(en)
|
1996-05-14 |
1999-08-11 |
Smithkline Beecham Corporation |
Novel compounds
|
|
KR100447918B1
(ko)
|
1996-07-25 |
2005-09-28 |
동아제약주식회사 |
대장을포함한위장관보호작용을갖는플라본및플라바논화합물
|
|
DE19630390A1
(de)
|
1996-07-26 |
1998-01-29 |
Chiron Behring Gmbh & Co |
Proteine, insbesondere Membranproteine von Helicobacter pylori, ihre Herstellung und Verwendung
|
|
EP0970966B1
(en)
|
1996-09-04 |
2008-02-20 |
Takara Bio Inc. |
Fungal antigens and process for producing the same
|
|
US5908934A
(en)
|
1996-09-26 |
1999-06-01 |
Bristol-Myers Squibb Company |
Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs
|
|
WO1998016247A1
(en)
|
1996-10-11 |
1998-04-23 |
The Regents Of The University Of California |
Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
|
|
US6420135B1
(en)
|
1996-10-31 |
2002-07-16 |
Human Genome Sciences, Inc. |
Streptococcus pneumoniae polynucleotides and sequences
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6299881B1
(en)
|
1997-03-24 |
2001-10-09 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
|
|
DE69819150T3
(de)
|
1997-06-06 |
2007-12-20 |
Dynavax Technologies Corp., San Diego |
Immunstimulierende oligonucleotide, zusammensetzungen davon, und verfahren zur verwendung davon
|
|
GB9712347D0
(en)
|
1997-06-14 |
1997-08-13 |
Smithkline Beecham Biolog |
Vaccine
|
|
GB9713156D0
(en)
|
1997-06-20 |
1997-08-27 |
Microbiological Res Authority |
Vaccines
|
|
US6800744B1
(en)
|
1997-07-02 |
2004-10-05 |
Genome Therapeutics Corporation |
Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
|
|
AU744986B2
(en)
|
1997-07-12 |
2002-03-07 |
Cancer Research Technology Limited |
Cyclin dependent kinase inhibiting purine derivatives
|
|
US5948413A
(en)
|
1997-07-17 |
1999-09-07 |
Board Of Trustees Operating Michigan State University |
Method and vaccine for treatment of pythiosis insidiosi in humans and lower animals
|
|
DE69815692T2
(de)
|
1997-09-05 |
2004-04-29 |
Glaxosmithkline Biologicals S.A. |
Öl in wasser emulsionen mit saponinen
|
|
CN100390283C
(zh)
|
1997-11-21 |
2008-05-28 |
根瑟特公司 |
肺炎衣原体的基因组序列和其多肽,片段以及其用途特别是用于诊断、预防和治疗感染
|
|
KR100735653B1
(ko)
|
1997-11-28 |
2007-07-06 |
세로노 제네틱스 인스티튜트 에스.에이. |
클라미디아 트라코마티스 게놈 서열과 폴리펩티드, 이의단편 및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도
|
|
UA67760C2
(uk)
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
|
RS49779B
(sr)
*
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
US6303114B1
(en)
|
1998-03-05 |
2001-10-16 |
The Medical College Of Ohio |
IL-12 enhancement of immune responses to T-independent antigens
|
|
GB9807721D0
(en)
|
1998-04-08 |
1998-06-10 |
Chiron Spa |
Antigen
|
|
KR20010042573A
(ko)
|
1998-04-09 |
2001-05-25 |
장 스테판느 |
애쥬번트 조성물
|
|
GB9810193D0
(en)
|
1998-05-12 |
1998-07-08 |
Smithkline Beecham Biolog |
Novel compounds
|
|
TR200003514T2
(tr)
|
1998-05-29 |
2002-05-21 |
Sugen Inc. |
Pirol ikame edilmiş 2-indolinon protein kinaz inhibitörleri
|
|
AP1393A
(en)
|
1998-09-30 |
2005-04-19 |
Wrair Walter Reid Army Institute Of Res |
Indolo [2,1-b] quinazole-6, 12-dione antimalarial compounds and methods of treating malaria therewith.
|
|
MXPA01003557A
(es)
|
1998-10-09 |
2004-04-05 |
Chiron Corp |
Secuencias genomicas de neisseria y metodos para su uso.
|
|
IL142395A0
(en)
|
1998-10-16 |
2002-03-10 |
Smithkline Beecham Biolog |
Adjuvant systems and vaccines
|
|
US20030083242A1
(en)
|
1998-11-06 |
2003-05-01 |
Alphonse Galdes |
Methods and compositions for treating or preventing peripheral neuropathies
|
|
JP2002529069A
(ja)
|
1998-11-12 |
2002-09-10 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
クラミジア・ニューモニエのゲノム配列
|
|
GB9828000D0
(en)
|
1998-12-18 |
1999-02-10 |
Chiron Spa |
Antigens
|
|
ATE346608T1
(de)
|
1999-03-19 |
2006-12-15 |
Glaxosmithkline Biolog Sa |
Impstoff gegen streptococcus pneumoniae
|
|
CA2370697C
(en)
|
1999-04-19 |
2012-03-06 |
Smithkline Beecham Biologicals S.A. |
Adjuvant composition comprising saponin and an immunostimulatory oligonucleotide
|
|
WO2000067161A2
(en)
|
1999-05-04 |
2000-11-09 |
Grant Lee H |
Method and apparatus for categorizing and retrieving network pages and sites
|
|
CA2379035A1
(en)
|
1999-07-13 |
2001-01-18 |
Shiro Akinaga |
Staurosporin derivatives
|
|
WO2001008636A2
(en)
|
1999-08-03 |
2001-02-08 |
The Ohio State University |
Polypeptides and polynucleotides for enhancing immune reactivity to her-2 protein
|
|
MXPA02003067A
(es)
|
1999-09-24 |
2002-09-30 |
Smithkline Beecham Biolog |
Uso de combinacion de ester sorbitano de polioxietileno y octoxinol como adjuvante y su uso en vacunas.
|
|
MXPA02003068A
(es)
|
1999-09-24 |
2002-09-30 |
Smithkline Beecham Biolog |
Adyuvante que comprende un eter o ester alquilo de polioxietileno y al menos un tensioactivo no ionico..
|
|
US7173038B1
(en)
|
1999-11-05 |
2007-02-06 |
Astrazeneca Ab |
Quinazoline derivatives as VEGF inhibitors
|
|
DK2289545T3
(en)
|
2000-01-17 |
2016-09-05 |
Glaxosmithkline Biologicals Sa |
Supplemented OMV vaccine against meningococcus
|
|
AT409085B
(de)
|
2000-01-28 |
2002-05-27 |
Cistem Biotechnologies Gmbh |
Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
|
|
CN1329390C
(zh)
|
2000-02-15 |
2007-08-01 |
苏根公司 |
吡咯取代的2-二氢吲哚酮蛋白激酶抑制剂
|
|
JP2003531148A
(ja)
|
2000-04-12 |
2003-10-21 |
ジェネーラ・コーポレーション |
保護されていない7−α−ヒドロキシ基を有する中間体を使用する、7−α−ヒドロキシ3−アミノ置換ステロイドの調製のためのプロセス
|
|
ES2280382T3
(es)
|
2000-06-30 |
2007-09-16 |
Glaxo Group Limited |
Compuestos de las sales ditosilato de quinazolina.
|
|
WO2002016351A1
(en)
*
|
2000-08-18 |
2002-02-28 |
Cor Therapeutics, Inc. |
Quinazoline derivatives as kinase inhibitors
|
|
AU8743001A
(en)
|
2000-08-28 |
2002-03-13 |
Aventis Pasteur |
Moraxella polypeptides and corresponding dna fragments and uses thereof
|
|
US6677450B2
(en)
|
2000-10-06 |
2004-01-13 |
Bristol-Myers Squibb Company |
Topoisomerase inhibitors
|
|
NZ540544A
(en)
|
2000-10-27 |
2007-08-31 |
Inst Genomic Research |
Nucleic acids and proteins from streptococcus groups A & B
|
|
WO2002062826A1
(fr)
|
2001-02-07 |
2002-08-15 |
Vadim Viktorovich Novikov |
Procede de fabrication des peptides
|
|
CA2447599C
(en)
|
2001-05-18 |
2015-04-28 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention, Technology Transfer Office |
Peptide vaccines against group a streptococci
|
|
WO2003004505A1
(en)
|
2001-07-02 |
2003-01-16 |
Debiopharm S.A. |
Oxaliplatin active substance with a very low content of oxalic acid
|
|
KR100484504B1
(ko)
|
2001-09-18 |
2005-04-20 |
학교법인 포항공과대학교 |
쿠커비투릴 유도체를 주인 분자로서 포함하고 있는 내포화합물 및 이를 포함한 약제학적 조성물
|
|
US20030134846A1
(en)
|
2001-10-09 |
2003-07-17 |
Schering Corporation |
Treatment of trypanosoma brucei with farnesyl protein transferase inhibitors
|
|
GB0126879D0
(en)
*
|
2001-11-08 |
2002-01-02 |
Astrazeneca Ab |
Combination therapy
|
|
AU2002316231A1
(en)
|
2002-02-19 |
2003-09-29 |
Xenoport, Inc. |
Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
|
|
GB0210128D0
(en)
|
2002-05-02 |
2002-06-12 |
Chiron Spa |
Nucleic acids and proteins from streptococcus groups A & B
|
|
US6900342B2
(en)
|
2002-05-10 |
2005-05-31 |
Dabur India Limited |
Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof
|
|
US6727272B1
(en)
|
2002-07-15 |
2004-04-27 |
Unitech Pharmaceuticals, Inc. |
Leflunomide analogs for treating rheumatoid arthritis
|
|
US20040047835A1
(en)
*
|
2002-09-06 |
2004-03-11 |
Cell Therapeutics, Inc. |
Combinatorial drug therapy using polymer drug conjugates
|
|
PT1551357E
(pt)
|
2002-09-13 |
2014-10-10 |
Novartis Vaccines & Diagnostic |
Vacina contra os estreptococos do grupo b
|
|
JPWO2004026341A1
(ja)
*
|
2002-09-19 |
2006-01-12 |
株式会社オリエントキャンサーセラピー |
ガンの免疫治療剤
|
|
MXPA05013260A
(es)
|
2003-06-26 |
2006-03-09 |
Chiron Corp |
Composiciones inmunogenicas para chlamydia trachomatis.
|
|
PT1648500E
(pt)
|
2003-07-31 |
2014-10-10 |
Novartis Vaccines & Diagnostic |
Composições imunogénicas para estreptococos piogenes
|