JP2013515490A5 - - Google Patents
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- Publication number
- JP2013515490A5 JP2013515490A5 JP2012546239A JP2012546239A JP2013515490A5 JP 2013515490 A5 JP2013515490 A5 JP 2013515490A5 JP 2012546239 A JP2012546239 A JP 2012546239A JP 2012546239 A JP2012546239 A JP 2012546239A JP 2013515490 A5 JP2013515490 A5 JP 2013515490A5
- Authority
- JP
- Japan
- Prior art keywords
- lactic acid
- composition
- acid bacterium
- antigen
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 19
- 239000000203 mixture Substances 0.000 claims 10
- 241000894006 Bacteria Species 0.000 claims 9
- 235000014655 lactic acid Nutrition 0.000 claims 9
- 239000004310 lactic acid Substances 0.000 claims 9
- 239000000427 antigen Substances 0.000 claims 6
- 102000036639 antigens Human genes 0.000 claims 6
- 108091007433 antigens Proteins 0.000 claims 6
- 230000003612 virological effect Effects 0.000 claims 3
- 101710154606 Hemagglutinin Proteins 0.000 claims 2
- 241000194036 Lactococcus Species 0.000 claims 2
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 2
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 2
- 101710176177 Protein A56 Proteins 0.000 claims 2
- 241000194017 Streptococcus Species 0.000 claims 2
- 229920002807 Thiomer Polymers 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000000185 hemagglutinin Substances 0.000 claims 2
- 229920001477 hydrophilic polymer Polymers 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 241000712461 unidentified influenza virus Species 0.000 claims 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 229920000609 methyl cellulose Polymers 0.000 claims 1
- 239000001923 methylcellulose Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 claims 1
- 230000003232 mucoadhesive effect Effects 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims 1
- 239000007909 solid dosage form Substances 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28966309P | 2009-12-23 | 2009-12-23 | |
| US61/289,663 | 2009-12-23 | ||
| USPCT/US2010/041792 | 2010-07-13 | ||
| PCT/US2010/041792 WO2011008735A1 (en) | 2009-07-13 | 2010-07-13 | Oral vaccines produced and administered using edible micro-organism |
| PCT/US2010/062034 WO2011079282A1 (en) | 2009-12-23 | 2010-12-23 | Immunoprotection by oral administration of recombinant lactococcus lactis mini-capsules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013515490A JP2013515490A (ja) | 2013-05-09 |
| JP2013515490A5 true JP2013515490A5 (enExample) | 2014-02-06 |
Family
ID=44196157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012546239A Pending JP2013515490A (ja) | 2009-12-23 | 2010-12-23 | 組み換え型乳酸連鎖球菌のミニカプセルの経口投与による免疫保護 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2515661A4 (enExample) |
| JP (1) | JP2013515490A (enExample) |
| CN (1) | CN102665422B (enExample) |
| WO (1) | WO2011079282A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014047625A1 (en) | 2012-09-24 | 2014-03-27 | Montana State University | Recombinant lactococcus lactis expressing escherichia coli colonization factor antigen i (cfa/i) fimbriae and their methods of use |
| CN102965388A (zh) * | 2012-12-07 | 2013-03-13 | 山东信得科技股份有限公司 | 一种表达猪传染性胃肠炎病毒基因工程菌制备方法 |
| WO2015156419A1 (en) | 2014-04-10 | 2015-10-15 | Riken | Compositions and methods for induction of th17 cells |
| CN104587458B (zh) * | 2014-12-04 | 2017-01-04 | 吉林医药学院 | 预防贾第虫病的二价dna疫苗及其肠溶制剂 |
| CN110511399B (zh) * | 2019-07-26 | 2022-03-04 | 广西大学 | 一种控释型纳米纤维素抗菌微凝胶的制备方法 |
| CN116083240B (zh) * | 2023-04-07 | 2023-08-29 | 深圳市第二人民医院(深圳市转化医学研究院) | 工程化细菌及其制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2278358B (en) * | 1992-02-27 | 1995-07-26 | Lynxvale Ltd | Heterologous gene expression in Lactococcus,and the expression products therefrom |
| BR9405996A (pt) * | 1993-03-11 | 1995-12-19 | Secretech Inc | Mucoadesivos poliméricos na distribuição de imunógenos em superfícies mucosais |
| US6328967B1 (en) * | 1998-03-12 | 2001-12-11 | Allergenics, Inc. | Delivery system to modulate immune response |
| ATE481108T1 (de) * | 1999-02-26 | 2010-10-15 | Novartis Vaccines & Diagnostic | Verwendung von bioadhaesiven und adjuvantien für die mukosale anwendung von antigenen |
| US8168228B2 (en) * | 2003-10-17 | 2012-05-01 | Sandoz Ag | Antibiotic clarithromycin micropellet compositions |
| US20050281795A1 (en) * | 2004-06-17 | 2005-12-22 | Amano Enzyme Usa., Ltd. And Amano Enzyme,Inc. | Controlled release formulations of enzymes, microorganisms, and antibodies with mucoadhesive polymers |
| CN101578111A (zh) * | 2006-04-21 | 2009-11-11 | 美国陶氏益农公司 | 禽流感疫苗和使用方法 |
| US20090324638A1 (en) * | 2006-06-12 | 2009-12-31 | Biopeptides Corp. | Live bacterial vaccine |
| WO2009064819A2 (en) * | 2007-11-13 | 2009-05-22 | Meritage Pharma, Inc. | Compositions for the treatment of gastrointestinal inflammation |
-
2010
- 2010-12-23 EP EP10840176.1A patent/EP2515661A4/en not_active Withdrawn
- 2010-12-23 WO PCT/US2010/062034 patent/WO2011079282A1/en not_active Ceased
- 2010-12-23 CN CN201080058158.4A patent/CN102665422B/zh not_active Expired - Fee Related
- 2010-12-23 JP JP2012546239A patent/JP2013515490A/ja active Pending
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