JP2012105660A5 - - Google Patents

Download PDF

Info

Publication number
JP2012105660A5
JP2012105660A5 JP2012014665A JP2012014665A JP2012105660A5 JP 2012105660 A5 JP2012105660 A5 JP 2012105660A5 JP 2012014665 A JP2012014665 A JP 2012014665A JP 2012014665 A JP2012014665 A JP 2012014665A JP 2012105660 A5 JP2012105660 A5 JP 2012105660A5
Authority
JP
Japan
Prior art keywords
odorant receptor
odorant
cell
cell line
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012014665A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012105660A (ja
JP5340430B2 (ja
Filing date
Publication date
Priority claimed from US11/156,516 external-priority patent/US7425445B2/en
Application filed filed Critical
Publication of JP2012105660A publication Critical patent/JP2012105660A/ja
Publication of JP2012105660A5 publication Critical patent/JP2012105660A5/ja
Application granted granted Critical
Publication of JP5340430B2 publication Critical patent/JP5340430B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2012014665A 2004-06-18 2012-01-26 匂い物質受容体のモジュレーター Expired - Lifetime JP5340430B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US58108704P 2004-06-18 2004-06-18
US60/581,087 2004-06-18
US58201104P 2004-06-22 2004-06-22
US60/582,011 2004-06-22
US11/156,516 US7425445B2 (en) 2004-06-18 2005-06-20 Modulators that promote cell surface expression of odorant receptors
US11/156,516 2005-06-20

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007516837A Division JP5022217B2 (ja) 2004-06-18 2005-06-20 匂い物質受容体のモジュレーター

Publications (3)

Publication Number Publication Date
JP2012105660A JP2012105660A (ja) 2012-06-07
JP2012105660A5 true JP2012105660A5 (enExample) 2012-12-13
JP5340430B2 JP5340430B2 (ja) 2013-11-13

Family

ID=36034502

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007516837A Expired - Fee Related JP5022217B2 (ja) 2004-06-18 2005-06-20 匂い物質受容体のモジュレーター
JP2012014665A Expired - Lifetime JP5340430B2 (ja) 2004-06-18 2012-01-26 匂い物質受容体のモジュレーター

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2007516837A Expired - Fee Related JP5022217B2 (ja) 2004-06-18 2005-06-20 匂い物質受容体のモジュレーター

Country Status (9)

Country Link
US (6) US7425445B2 (enExample)
EP (2) EP1771582A4 (enExample)
JP (2) JP5022217B2 (enExample)
CN (1) CN101087879B (enExample)
AU (2) AU2005258061C1 (enExample)
CA (1) CA2571080C (enExample)
DK (1) DK2031063T3 (enExample)
PL (1) PL2031063T3 (enExample)
WO (1) WO2006002161A2 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2647224C (en) * 2006-03-30 2015-12-29 Duke University Identification of a novel gene underlying familial spastic paraplegia
US8298781B2 (en) * 2007-05-08 2012-10-30 Duke University Compositions and methods for characterizing and regulating olfactory sensation
JP5690467B2 (ja) * 2008-04-11 2015-03-25 花王株式会社 嗅覚感度抑制剤のスクリーニング法
WO2011069156A2 (en) 2009-12-04 2011-06-09 Duke University Compositions and methods for enhancing odorant receptor activity
JP5520173B2 (ja) * 2010-09-16 2014-06-11 花王株式会社 ミューゲ香料素材の探索方法
WO2012056603A1 (ja) 2010-10-25 2012-05-03 パナソニック株式会社 キメラ嗅覚受容体を用いてcAMPを産生する方法
WO2012139526A1 (zh) * 2011-04-14 2012-10-18 上海交通大学医学院 一种配位金属的气味化合物的探测方法
JP5921226B2 (ja) * 2012-02-02 2016-05-24 花王株式会社 ミューゲ香料素材の探索方法
US20130210775A1 (en) 2012-02-09 2013-08-15 Kao Corporation Agent for inhibiting odor of pyrazine derivatives
AU2013311316A1 (en) * 2012-09-10 2015-03-26 The Johns Hopkins University Compositions and methods for increasing the expression and signalling of proteins on cell surfaces
MX371282B (es) 2013-06-29 2020-01-24 Firmenich & Cie Metodos para identificar, aislar y usar receptores de odorizantes y aroma.
EP2832347B1 (en) 2013-08-02 2018-01-31 Takasago International Corporation Method for identifying patchouli odorant materials
US10041935B2 (en) 2013-08-05 2018-08-07 New York University Identification of olfactory receptors sensitive to different odorants
CN105917228B (zh) * 2013-12-16 2018-11-30 莫奈尔化学感官中心 鉴定嗅觉受体调节剂的方法
WO2015116771A1 (en) 2014-01-29 2015-08-06 The Johns Hopkins University Compositions and methods for increasing the expression and signalling of proteins on cell surfaces
US11267852B2 (en) 2015-06-10 2022-03-08 Firmenich Sa Cell lines for screening odorant and aroma receptors
US10512253B2 (en) 2015-08-03 2019-12-24 Research Foundation Of The City University Of New York DNA sequence that increases odorant receptor representation in the olfactory system
AU2017222572A1 (en) 2016-02-24 2018-08-23 Aromyx Corporation Biosensor for detecting smell, scent and taste
MX2019003507A (es) * 2016-09-30 2019-08-01 Mars Inc Metodos de evaluacion usando receptores olfatorios y compuestos novedosos identificados usando los mismos.
WO2018081588A1 (en) 2016-10-27 2018-05-03 Duke University Methods for vapor detection and discrimination with mammalian odorant receptors expressed in heterologous cells
WO2018151875A2 (en) 2016-12-30 2018-08-23 Research Foundation Of The City University Of New York Biosensor exhibiting sensitivity to trinitrotoluene
EP3573944B1 (en) 2017-01-30 2022-03-02 ChemCom S.A. Compounds reducing malodour perception and the use thereof
WO2018163800A1 (ja) * 2017-03-07 2018-09-13 高砂香料工業株式会社 マリンノートを呈する香料素材のスクリーニング方法
US10209239B1 (en) 2017-08-16 2019-02-19 Aromyx Corporation Method of making an aromagraph comprising ectopic olfactory receptors
EP3814371A4 (en) 2018-06-26 2022-07-20 Duke University Synthetic odorant receptors
US12251991B2 (en) 2020-08-20 2025-03-18 Denso International America, Inc. Humidity control for olfaction sensors
US12269315B2 (en) 2020-08-20 2025-04-08 Denso International America, Inc. Systems and methods for measuring and managing odor brought into rental vehicles
US11813926B2 (en) 2020-08-20 2023-11-14 Denso International America, Inc. Binding agent and olfaction sensor
US11828210B2 (en) 2020-08-20 2023-11-28 Denso International America, Inc. Diagnostic systems and methods of vehicles using olfaction
US11760169B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Particulate control systems and methods for olfaction sensors
US12377711B2 (en) 2020-08-20 2025-08-05 Denso International America, Inc. Vehicle feature control systems and methods based on smoking
US11636870B2 (en) 2020-08-20 2023-04-25 Denso International America, Inc. Smoking cessation systems and methods
US11932080B2 (en) 2020-08-20 2024-03-19 Denso International America, Inc. Diagnostic and recirculation control systems and methods
US11760170B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Olfaction sensor preservation systems and methods
US12017506B2 (en) 2020-08-20 2024-06-25 Denso International America, Inc. Passenger cabin air control systems and methods
US11881093B2 (en) 2020-08-20 2024-01-23 Denso International America, Inc. Systems and methods for identifying smoking in vehicles
GB202108867D0 (en) 2021-06-21 2021-08-04 Givaudan Sa Screening system
EP4634213A1 (en) 2022-12-15 2025-10-22 Givaudan SA Modified olfactory receptors
JP2024132485A (ja) * 2023-03-17 2024-10-01 住友化学株式会社 ヒトリガ科の昆虫由来細胞
CN116200456B (zh) * 2023-04-27 2023-07-28 汉王科技股份有限公司 利用嗅觉受体检测食品变质的方法
WO2025257381A1 (en) 2024-06-14 2025-12-18 Givaudan Sa Modified olfactory receptors
EP4664463A1 (en) 2024-06-14 2025-12-17 Givaudan SA Computer-implemented method for olfactory property prediction
CN118501118B (zh) * 2024-07-16 2024-10-29 汉王科技股份有限公司 一种基于细胞的生物荧光能量共振转移检测系统及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
AU3069189A (en) 1988-02-05 1989-08-25 Trustees Of Columbia University In The City Of New York, The Retroviral packaging cell lines and processes of using same
EP0432216A1 (en) 1988-09-01 1991-06-19 Whitehead Institute For Biomedical Research Recombinant retroviruses with amphotropic and ecotropic host ranges
GB8901778D0 (en) 1989-01-27 1989-03-15 Univ Court Of The University O Manipulatory technique
ES2310924T3 (es) 1993-07-13 2009-01-16 Centelion Vectores adenovirales defectivos y utilizacion en terapia genica.
FR2715847B1 (fr) 1994-02-08 1996-04-12 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
FR2730637B1 (fr) 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
US5993778A (en) * 1997-05-07 1999-11-30 Firestein; Stuart J. Functional expression of, and assay for, functional cellular receptors in vivo
WO2001051609A1 (en) * 2000-01-14 2001-07-19 The Johns Hopkins University Isolation and in vitro differentiation of conditionally immortalized murine olfactory receptor neurons
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
CA2459137A1 (en) * 2001-09-14 2003-03-27 Incyte Genomics, Inc. Receptors and membrane-associated proteins
AU2003222849A1 (en) * 2002-05-02 2003-12-02 Evotec Neurosciences Gmbh Diagnostic and therapeutic use of ensadin-0255 gene and protein for neurodegenerative diseases
AU2003230273A1 (en) * 2002-05-07 2003-11-11 Immunex Corporation Cytokine polypeptides
AU2003303305A1 (en) * 2002-10-02 2004-09-30 Nuvelo,Inc. Novel nucleic acids and polypeptides

Similar Documents

Publication Publication Date Title
JP2012105660A5 (enExample)
Sun et al. Mosaic mutant analysis identifies PDGFRα/PDGFRβ as negative regulators of adipogenesis
JP2015525065A5 (enExample)
HRP20190542T1 (hr) Životinje s humaniziranim il-15
JP2020500563A5 (enExample)
WO2012175643A3 (en) Binding domains directed against gpcr:g protein complexes and uses derived thereof
JP2016500263A5 (enExample)
JP2012249614A5 (enExample)
JP2014519823A5 (enExample)
CY1120087T1 (el) Συνθεση εξωκυτταριας θεμελιας ουσιας (ecm, extra cellular matrix), πλατφορμα μικροπεριβαλλοντος ογκου και οι μεθοδοι τους
JP2017514496A5 (enExample)
JP2013063072A5 (enExample)
CL2013002361A1 (es) Metodo para medir actividad de células natural killer (nk); kit para medir dicha actividad; proteína de fusión; composicion para activar células nk; polipéptido, oligonucleótido, vector y célula hospedera que comprenden la proteína;
JP2014534207A5 (enExample)
JP2018505139A5 (enExample)
CO6670523A2 (es) Anticuerpos específicos para proteína de activación fibroblástica (fap), polinucleotidos que codifican dichos anticuerpos, y vectores y células huesped que comprenden dichos nucleótidos
EP2576626A4 (en) STABLE, FUNCTIONAL AND CHIMERIC CELL BIOHYDROLASE ENZYMES OF CLASS 1
PH12015502849B1 (en) Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkers
CL2017002233A1 (es) Un factor de coagulación (fvii o fviia) modificado con tres péptidos carboxi terminal de gonadotropina coriónica unidos al carboxi terminal de fvii o fviia; polinucleótido que lo codifica; composición farmacéutica que lo comprende; uso de fvii o fviia modificado para el tratamiento de coagulación de la sangre o un trastorno de coagulación; método para extender la vía media biológica de un factor de coagulación; método para producir dicho fvii o fviia.
JP2009539082A5 (enExample)
BRPI0908747A2 (pt) Ligantes esteróides e seu uso em modulação de comutador genético
JP2012524523A5 (enExample)
BR112013025999A2 (pt) material catalítico, e, método para fornecer o material catalítico
EP2670755A1 (en) Trifunctional crosslinking reagents
CO6480963A2 (es) Aptamero para quimasa y su uso