JP2012105660A5 - - Google Patents

Download PDF

Info

Publication number
JP2012105660A5
JP2012105660A5 JP2012014665A JP2012014665A JP2012105660A5 JP 2012105660 A5 JP2012105660 A5 JP 2012105660A5 JP 2012014665 A JP2012014665 A JP 2012014665A JP 2012014665 A JP2012014665 A JP 2012014665A JP 2012105660 A5 JP2012105660 A5 JP 2012105660A5
Authority
JP
Japan
Prior art keywords
odorant receptor
odorant
cell
cell line
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012014665A
Other languages
English (en)
Japanese (ja)
Other versions
JP5340430B2 (ja
JP2012105660A (ja
Filing date
Publication date
Priority claimed from US11/156,516 external-priority patent/US7425445B2/en
Application filed filed Critical
Publication of JP2012105660A publication Critical patent/JP2012105660A/ja
Publication of JP2012105660A5 publication Critical patent/JP2012105660A5/ja
Application granted granted Critical
Publication of JP5340430B2 publication Critical patent/JP5340430B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2012014665A 2004-06-18 2012-01-26 匂い物質受容体のモジュレーター Expired - Lifetime JP5340430B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US58108704P 2004-06-18 2004-06-18
US60/581,087 2004-06-18
US58201104P 2004-06-22 2004-06-22
US60/582,011 2004-06-22
US11/156,516 2005-06-20
US11/156,516 US7425445B2 (en) 2004-06-18 2005-06-20 Modulators that promote cell surface expression of odorant receptors

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007516837A Division JP5022217B2 (ja) 2004-06-18 2005-06-20 匂い物質受容体のモジュレーター

Publications (3)

Publication Number Publication Date
JP2012105660A JP2012105660A (ja) 2012-06-07
JP2012105660A5 true JP2012105660A5 (enExample) 2012-12-13
JP5340430B2 JP5340430B2 (ja) 2013-11-13

Family

ID=36034502

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007516837A Expired - Fee Related JP5022217B2 (ja) 2004-06-18 2005-06-20 匂い物質受容体のモジュレーター
JP2012014665A Expired - Lifetime JP5340430B2 (ja) 2004-06-18 2012-01-26 匂い物質受容体のモジュレーター

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2007516837A Expired - Fee Related JP5022217B2 (ja) 2004-06-18 2005-06-20 匂い物質受容体のモジュレーター

Country Status (9)

Country Link
US (6) US7425445B2 (enExample)
EP (2) EP1771582A4 (enExample)
JP (2) JP5022217B2 (enExample)
CN (1) CN101087879B (enExample)
AU (2) AU2005258061C1 (enExample)
CA (1) CA2571080C (enExample)
DK (1) DK2031063T3 (enExample)
PL (1) PL2031063T3 (enExample)
WO (1) WO2006002161A2 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2647224C (en) * 2006-03-30 2015-12-29 Duke University Identification of a novel gene underlying familial spastic paraplegia
EP2155910A4 (en) * 2007-05-08 2010-06-02 Univ Duke COMPOSITIONS AND METHODS FOR CHARACTERIZING AND REGULATING ODOR PERCEPTION
JP5690467B2 (ja) * 2008-04-11 2015-03-25 花王株式会社 嗅覚感度抑制剤のスクリーニング法
US9068226B2 (en) 2009-12-04 2015-06-30 Duke University Compositions and methods for enhancing odorant receptor activity
JP5520173B2 (ja) * 2010-09-16 2014-06-11 花王株式会社 ミューゲ香料素材の探索方法
WO2012056603A1 (ja) 2010-10-25 2012-05-03 パナソニック株式会社 キメラ嗅覚受容体を用いてｃＡＭＰを産生する方法
WO2012139526A1 (zh) * 2011-04-14 2012-10-18 上海交通大学医学院 一种配位金属的气味化合物的探测方法
JP5921226B2 (ja) * 2012-02-02 2016-05-24 花王株式会社 ミューゲ香料素材の探索方法
US20130210775A1 (en) 2012-02-09 2013-08-15 Kao Corporation Agent for inhibiting odor of pyrazine derivatives
WO2014037800A2 (en) * 2012-09-10 2014-03-13 Johns Hopkins University Compositions and methods for increasing the expression and signalling of proteins on cell surfaces
BR112015032700B1 (pt) * 2013-06-29 2022-12-20 Firmenich Sa Métodos de identificação, isolamento e uso de receptores de aroma e odorizante
ES2665906T3 (es) 2013-08-02 2018-04-30 Takasago International Corporation Método para identificar materiales odorantes de pachulí
US10041935B2 (en) 2013-08-05 2018-08-07 New York University Identification of olfactory receptors sensitive to different odorants
CN105917228B (zh) 2013-12-16 2018-11-30 莫奈尔化学感官中心 鉴定嗅觉受体调节剂的方法
WO2015116771A1 (en) 2014-01-29 2015-08-06 The Johns Hopkins University Compositions and methods for increasing the expression and signalling of proteins on cell surfaces
EP3726218B1 (en) * 2015-06-10 2023-08-09 Firmenich Sa Cell lines for screening odorant and aroma receptors
EP3331990A4 (en) * 2015-08-03 2019-04-03 Research Foundation Of The City University Of New York THE ODOR RECEPTOR PRESENTATION IN THE OLFACTORY SYSTEM INCREASING DNA SEQUENCE
EP3419996A4 (en) * 2016-02-24 2019-09-18 Aromyx Corporation BIOSENSOR TO ODOR DETECTION SCENT AND TASTE
EP3519815A1 (en) * 2016-09-30 2019-08-07 Mars, Incorporated Screening methods using olfactory receptors and novel compounds identified using the same
US11029308B2 (en) 2016-10-27 2021-06-08 Duke University Methods for vapor detection and discrimination with mammalian odorant receptors expressed in heterologous cells
US11255830B2 (en) 2016-12-30 2022-02-22 Research Foundation Of The City University Of New York Biosensor exhibiting sensitivity to trinitrotoluene
JP7182566B2 (ja) 2017-01-30 2022-12-02 ケムコム エス アー 悪臭知覚を低減する化合物およびその使用
WO2018163800A1 (ja) * 2017-03-07 2018-09-13 高砂香料工業株式会社 マリンノートを呈する香料素材のスクリーニング方法
US10209239B1 (en) 2017-08-16 2019-02-19 Aromyx Corporation Method of making an aromagraph comprising ectopic olfactory receptors
WO2020006108A2 (en) * 2018-06-26 2020-01-02 Duke University Synthetic odorant receptors
US11760170B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Olfaction sensor preservation systems and methods
US11636870B2 (en) 2020-08-20 2023-04-25 Denso International America, Inc. Smoking cessation systems and methods
US12017506B2 (en) 2020-08-20 2024-06-25 Denso International America, Inc. Passenger cabin air control systems and methods
US11760169B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Particulate control systems and methods for olfaction sensors
US11932080B2 (en) 2020-08-20 2024-03-19 Denso International America, Inc. Diagnostic and recirculation control systems and methods
US11881093B2 (en) 2020-08-20 2024-01-23 Denso International America, Inc. Systems and methods for identifying smoking in vehicles
US12269315B2 (en) 2020-08-20 2025-04-08 Denso International America, Inc. Systems and methods for measuring and managing odor brought into rental vehicles
US11813926B2 (en) 2020-08-20 2023-11-14 Denso International America, Inc. Binding agent and olfaction sensor
US12377711B2 (en) 2020-08-20 2025-08-05 Denso International America, Inc. Vehicle feature control systems and methods based on smoking
US12251991B2 (en) 2020-08-20 2025-03-18 Denso International America, Inc. Humidity control for olfaction sensors
US11828210B2 (en) 2020-08-20 2023-11-28 Denso International America, Inc. Diagnostic systems and methods of vehicles using olfaction
GB202108867D0 (en) 2021-06-21 2021-08-04 Givaudan Sa Screening system
CN120603844A (zh) 2022-12-15 2025-09-05 奇华顿股份有限公司 经修饰的嗅觉受体
JP2024132485A (ja) * 2023-03-17 2024-10-01 住友化学株式会社 ヒトリガ科の昆虫由来細胞
CN116200456B (zh) * 2023-04-27 2023-07-28 汉王科技股份有限公司 利用嗅觉受体检测食品变质的方法
EP4664463A1 (en) 2024-06-14 2025-12-17 Givaudan SA Computer-implemented method for olfactory property prediction
WO2025257381A1 (en) 2024-06-14 2025-12-18 Givaudan Sa Modified olfactory receptors
CN118501118B (zh) * 2024-07-16 2024-10-29 汉王科技股份有限公司 一种基于细胞的生物荧光能量共振转移检测系统及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
WO1989007150A1 (en) 1988-02-05 1989-08-10 The Trustees Of Columbia University In The City Of Retroviral packaging cell lines and processes of using same
JP3082204B2 (ja) 1988-09-01 2000-08-28 ホワイトヘッド・インスティチュート・フォー・バイオメディカル・リサーチ 両栄養性および環境栄養性宿主域を持つ組換え体レトロウイルス
GB8901778D0 (en) 1989-01-27 1989-03-15 Univ Court Of The University O Manipulatory technique
KR100356615B1 (ko) 1993-07-13 2003-04-03 아방티 파르마 소시에테 아노님 결함아데노바이러스벡터및유전자치료에서그의사용
FR2715847B1 (fr) 1994-02-08 1996-04-12 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
FR2730637B1 (fr) 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
US5993778A (en) * 1997-05-07 1999-11-30 Firestein; Stuart J. Functional expression of, and assay for, functional cellular receptors in vivo
WO2001051609A1 (en) * 2000-01-14 2001-07-19 The Johns Hopkins University Isolation and in vitro differentiation of conditionally immortalized murine olfactory receptor neurons
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
AU2002326910A1 (en) * 2001-09-14 2003-04-01 Incyte Genomics, Inc. Receptors and membrane-associated proteins
EP1499897A1 (en) * 2002-05-02 2005-01-26 EVOTEC Neurosciences GmbH Diagnostic and therapeutic use of ensadin-0255 gene and protein for neurodegenerative diseases
WO2003095614A2 (en) * 2002-05-07 2003-11-20 Immunex Corporation Cytokine polypeptides
AU2003303305A1 (en) * 2002-10-02 2004-09-30 Nuvelo,Inc. Novel nucleic acids and polypeptides

Similar Documents

Publication Publication Date Title
JP2012105660A5 (enExample)
Sun et al. Mosaic mutant analysis identifies PDGFRα/PDGFRβ as negative regulators of adipogenesis
JP2020500563A5 (enExample)
JP2016500263A5 (enExample)
BR112015023394B8 (pt) Sistema e complexo bioluminescente
JP2012249614A5 (enExample)
JP2014519823A5 (enExample)
PH12013500336A1 (en) Peptide or peptide complex binding to alpha2 integrin and methods and uses involving the same
JP2017514496A5 (enExample)
EP4282882A3 (en) Binding domains directed against gpcr:g protein complexes and uses derived thereof
JP2013063072A5 (enExample)
CL2013002361A1 (es) Metodo para medir actividad de células natural killer (nk); kit para medir dicha actividad; proteína de fusión; composicion para activar células nk; polipéptido, oligonucleótido, vector y célula hospedera que comprenden la proteína;
JP2014534207A5 (enExample)
JP2018505139A5 (enExample)
EP3636776C0 (en) METHODS FOR ANALYSIS OF NUCLEIC SEQUENCE INFORMATION USING GC BIAS, POSSIBLY FOR THE DETECTION OF FETAL NUCLEIC ACID ABNORMALITIES
MX353382B (es) Moleculas de union polipeptido de larga duracion.
CO6670523A2 (es) Anticuerpos específicos para proteína de activación fibroblástica (fap), polinucleotidos que codifican dichos anticuerpos, y vectores y células huesped que comprenden dichos nucleótidos
EP2576626A4 (en) STABLE, FUNCTIONAL AND CHIMERIC CELL BIOHYDROLASE ENZYMES OF CLASS 1
CL2017002233A1 (es) Un factor de coagulación (fvii o fviia) modificado con tres péptidos carboxi terminal de gonadotropina coriónica unidos al carboxi terminal de fvii o fviia; polinucleótido que lo codifica; composición farmacéutica que lo comprende; uso de fvii o fviia modificado para el tratamiento de coagulación de la sangre o un trastorno de coagulación; método para extender la vía media biológica de un factor de coagulación; método para producir dicho fvii o fviia.
PH12015502849A1 (en) Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkers
JP2009539082A5 (enExample)
JP2012524523A5 (enExample)
BR112013025999A2 (pt) material catalítico, e, método para fornecer o material catalítico
EP2670755A1 (en) Trifunctional crosslinking reagents
WO2014205344A3 (en) Virion display array for profiling functions and interactions of human membrane proteins