JP2012000112A5 - - Google Patents
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- JP2012000112A5 JP2012000112A5 JP2011166505A JP2011166505A JP2012000112A5 JP 2012000112 A5 JP2012000112 A5 JP 2012000112A5 JP 2011166505 A JP2011166505 A JP 2011166505A JP 2011166505 A JP2011166505 A JP 2011166505A JP 2012000112 A5 JP2012000112 A5 JP 2012000112A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- nucleic acid
- seq
- sequence
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 102000039446 nucleic acids Human genes 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 9
- 150000007523 nucleic acids Chemical class 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 206010035664 Pneumonia Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 206010053555 Arthritis bacterial Diseases 0.000 claims 1
- 208000031729 Bacteremia Diseases 0.000 claims 1
- 206010007882 Cellulitis Diseases 0.000 claims 1
- 206010010741 Conjunctivitis Diseases 0.000 claims 1
- 206010014568 Empyema Diseases 0.000 claims 1
- 201000009906 Meningitis Diseases 0.000 claims 1
- 206010031252 Osteomyelitis Diseases 0.000 claims 1
- 206010033078 Otitis media Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 206010006451 bronchitis Diseases 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000001606 epiglottitis Diseases 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 208000008494 pericarditis Diseases 0.000 claims 1
- 201000009890 sinusitis Diseases 0.000 claims 1
- 208000019206 urinary tract infection Diseases 0.000 claims 1
- 239000012646 vaccine adjuvant Substances 0.000 claims 1
- 229940124931 vaccine adjuvant Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0410866.8A GB0410866D0 (en) | 2004-05-14 | 2004-05-14 | Haemophilius influenzae |
| GB0410866.8 | 2004-05-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007512595A Division JP2008506364A (ja) | 2004-05-14 | 2005-05-16 | 型分類不能なＨａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ由来のポリペプチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012000112A JP2012000112A (ja) | 2012-01-05 |
| JP2012000112A5 true JP2012000112A5 (OSRAM) | 2012-04-05 |
Family
ID=32527109
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007512595A Withdrawn JP2008506364A (ja) | 2004-05-14 | 2005-05-16 | 型分類不能なＨａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ由来のポリペプチド |
| JP2011166505A Pending JP2012000112A (ja) | 2004-05-14 | 2011-07-29 | 型分類不能なＨａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ由来のポリペプチド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007512595A Withdrawn JP2008506364A (ja) | 2004-05-14 | 2005-05-16 | 型分類不能なＨａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ由来のポリペプチド |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7749518B2 (OSRAM) |
| EP (5) | EP2341069A1 (OSRAM) |
| JP (2) | JP2008506364A (OSRAM) |
| CN (1) | CN1997663A (OSRAM) |
| BR (1) | BRPI0511118A (OSRAM) |
| CA (1) | CA2566632A1 (OSRAM) |
| GB (1) | GB0410866D0 (OSRAM) |
| IN (1) | IN2015KN00290A (OSRAM) |
| RU (1) | RU2432357C2 (OSRAM) |
| WO (1) | WO2005111066A2 (OSRAM) |
Families Citing this family (63)
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|---|---|---|---|---|
| CN101139590B (zh) * | 2000-02-28 | 2012-07-18 | 启龙股份公司 | 奈瑟球菌蛋白质的杂交表达 |
| DE60335477D1 (de) * | 2002-10-11 | 2011-02-03 | Novartis Vaccines & Diagnostic | Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| BRPI0609460A2 (pt) * | 2005-03-30 | 2010-04-13 | Novartis Vaccines & Diagnostics Inc | haemophilus influenzae tipo b |
| CA2612240A1 (en) | 2005-06-16 | 2006-12-28 | Children's Hospital, Inc. | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
| US8092811B2 (en) | 2005-08-10 | 2012-01-10 | Arne Forsgren Ab | Interaction of Moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system |
| NO346497B1 (no) | 2006-01-17 | 2022-09-05 | Arne Forsgren | Overflateeksponert haemophilus influenzae protein (protein E, pE) |
| US9132183B2 (en) * | 2007-03-09 | 2015-09-15 | Newport Laboratories | Modified live (JMSO strain) Haemophilus parasuis vaccine |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| BRPI0923006A2 (pt) * | 2008-12-17 | 2016-03-08 | Novartis Ag | vacinas meningococicas incluindo receptor de hemoglobina |
| US8617574B2 (en) * | 2009-02-13 | 2013-12-31 | Valneva Austria Gmbh | Nontypable Haemophilus influenzae antigens |
| ITMI20090946A1 (it) | 2009-05-28 | 2010-11-29 | Novartis Ag | Espressione di proteine ricombinanti |
| US9770463B2 (en) | 2010-07-06 | 2017-09-26 | Glaxosmithkline Biologicals Sa | Delivery of RNA to different cell types |
| EP2591114B1 (en) | 2010-07-06 | 2016-06-08 | GlaxoSmithKline Biologicals SA | Immunisation of large mammals with low doses of rna |
| DK3243526T3 (da) | 2010-07-06 | 2020-02-17 | Glaxosmithkline Biologicals Sa | Levering af rna til at udløse flere immunsignalveje |
| PL2590676T3 (pl) | 2010-07-06 | 2017-02-28 | Glaxosmithkline Biologicals Sa | Wirionopodobne cząstki dostarczające dla autoreplikujących się cząsteczek rna |
| BR112013000244A2 (pt) | 2010-07-06 | 2016-05-17 | Novartis Ag | lipossomas com lipídeos apresentando pka vantajoso para administração de rna |
| RS63315B1 (sr) | 2010-08-31 | 2022-07-29 | Glaxosmithkline Biologicals Sa | Pegilovani lipozomi za isporuku rnk koja kodira imunogen |
| JP5908477B2 (ja) | 2010-08-31 | 2016-04-26 | ノバルティス アーゲー | タンパク質をコードするｒｎａのリポソームによる送達に適した脂質 |
| CA2814386C (en) | 2010-10-11 | 2019-08-20 | Novartis Ag | Antigen delivery platforms |
| TW201302779A (zh) | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
| CN103687613A (zh) * | 2011-05-11 | 2014-03-26 | 里斯贝克保健瑞典股份公司 | 蛋白f-具有层粘连蛋白和玻连蛋白结合性能的新的流感嗜血杆菌粘附素 |
| EP4115875A1 (en) | 2011-07-06 | 2023-01-11 | GlaxoSmithKline Biologicals S.A. | Liposomes having useful n:p ratio for delivery of rna molecules |
| CA2840989A1 (en) | 2011-07-06 | 2013-01-10 | Novartis Ag | Immunogenic combination compositions and uses thereof |
| SG10201602456WA (en) | 2011-08-31 | 2016-04-28 | Novartis Ag | Pegylated liposomes for delivery of immunogen-encoding rna |
| US10279026B2 (en) * | 2012-04-26 | 2019-05-07 | Glaxosmithkline Biologicals Sa | Antigens and antigen combinations |
| RU2727476C2 (ru) | 2012-04-26 | 2020-07-21 | Новартис Аг | Антигены и антигенные композиции |
| RU2662970C2 (ru) | 2012-09-18 | 2018-07-31 | Новартис Аг | Везикулы наружной мембраны |
| CN107879960B (zh) | 2013-03-08 | 2021-06-22 | 诺华股份有限公司 | 用于传递活性成分的脂质和脂质组合物 |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
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| WO2015095346A1 (en) | 2013-12-19 | 2015-06-25 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| PT3083556T (pt) | 2013-12-19 | 2020-03-05 | Novartis Ag | Lípidos e composições lipídicas para a entrega de agentes ativos |
| WO2016010840A1 (en) | 2014-07-16 | 2016-01-21 | Novartis Ag | Method of encapsulating a nucleic acid in a lipid nanoparticle host |
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| JP6731912B2 (ja) | 2014-09-05 | 2020-07-29 | ノバルティス アーゲー | 活性物質の送達用の脂質および脂質組成物 |
| EP3061826A1 (en) | 2015-02-27 | 2016-08-31 | Novartis AG | Flavivirus replicons |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| EP3650043A3 (en) * | 2015-06-09 | 2020-07-29 | The Board of Regents of the University of Oklahoma | Compositions and treatments for haemophilus influenzae |
| US20180207067A1 (en) | 2015-07-14 | 2018-07-26 | Research Institute at Nationwide Children's Hospit al | Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity |
| HK1255383A1 (zh) * | 2015-07-31 | 2019-08-16 | The Research Institute At Nationwide Children's Hospital | 去除生物膜的肽及抗體 |
| WO2017066719A2 (en) | 2015-10-14 | 2017-04-20 | Research Institute At Nationwide Children's Hospital | Hu specific interfering agents |
| KR20180135493A (ko) * | 2016-04-27 | 2018-12-20 | 바이오셀즈(베이징) 바이오테크 코., 엘티디. | 흥분성 신경독성 관련 손상의 치료 방법 |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| EP3565589A1 (en) | 2017-01-04 | 2019-11-13 | Research Institute at Nationwide Children's Hospital | Dnabii vaccines and antibodies with enhanced activity |
| WO2018129092A1 (en) * | 2017-01-04 | 2018-07-12 | Research Institute At Nationwide Children's Hospital | Antibody fragments for the treatment of biofilm-related disorders |
| US20180221468A1 (en) * | 2017-01-19 | 2018-08-09 | Iowa State University Research Foundation, Inc. | Haemophilus influenzae immunogen |
| EP3595445B1 (en) | 2017-03-15 | 2024-09-04 | The Research Institute at Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| EP3860718A4 (en) | 2018-10-05 | 2022-08-31 | Research Institute at Nationwide Children's Hospital | HMGB1 PROTEIN DERIVATIVES FOR BIOFILM REMOVAL |
| US20220143168A1 (en) * | 2019-02-27 | 2022-05-12 | Evaxion Biotech A/S | Vaccines targeting H. influenzae |
| BR112021026890A2 (pt) | 2019-07-08 | 2022-03-15 | Res Inst Nationwide Childrens Hospital | Composições de anticorpo para interromper biofilmes |
| EP4110906A4 (en) * | 2020-02-28 | 2024-03-20 | Trait Biosciences, Inc. | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE GLYCOSYLATION OF CANNABINOID COMPOUNDS |
| US12116614B2 (en) | 2020-06-30 | 2024-10-15 | Research Institute At Nationwide Children's Hospital | Methods for determining antibiotic sensitivity |
| US20220218622A1 (en) | 2020-10-14 | 2022-07-14 | George Mason Research Foundation, Inc. | Ionizable lipids and methods of manufacture and use thereof |
| CN115678869B (zh) * | 2021-07-28 | 2025-08-29 | 梅花(上海)生物科技有限公司 | 一株重组菌株及其生产氨基酸的方法 |
| US20240350410A1 (en) | 2021-08-16 | 2024-10-24 | Glaxosmithkline Biologicals Sa | Freeze-drying of lipid nanoparticles (lnps) encapsulating rna and formulations thereof |
| US20250134824A1 (en) | 2021-08-16 | 2025-05-01 | Glaxosmithkline Biologicals Sa | Low-dose lyophilized rna vaccines and methods for preparing and using the same |
| CN114574456B (zh) * | 2022-03-18 | 2022-08-12 | 华南理工大学 | 一种亚硝酸盐还原酶突变体及其编码基因和应用 |
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| CN116236575B (zh) * | 2023-03-07 | 2025-03-25 | 北京化工大学 | 一种光控偶联型纳米探针及其制备方法、光控偶联的纳米颗粒组合物与应用 |
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| JP2006519605A (ja) * | 2003-03-06 | 2006-08-31 | チルドレンズ ホスピタル， インコーポレイテッド | 類型不能ｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅの中耳炎単離株の遺伝子 |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| CA2612240A1 (en) | 2005-06-16 | 2006-12-28 | Children's Hospital, Inc. | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
| NO346497B1 (no) | 2006-01-17 | 2022-09-05 | Arne Forsgren | Overflateeksponert haemophilus influenzae protein (protein E, pE) |
| AT507928B1 (de) | 2008-06-30 | 2015-09-15 | Coil Holding Gmbh | Drosselspule für elektrische energieversorgungsnetze mit reduzierten schallemissionen |
| WO2011106661A1 (en) | 2010-02-25 | 2011-09-01 | B/E Aerospace, Inc. | Calibration method for led lighting systems |
-
2004
- 2004-05-14 GB GBGB0410866.8A patent/GB0410866D0/en not_active Ceased
-
2005
- 2005-05-16 EP EP10190386A patent/EP2341069A1/en not_active Withdrawn
- 2005-05-16 RU RU2006144093/10A patent/RU2432357C2/ru not_active IP Right Cessation
- 2005-05-16 EP EP10194789A patent/EP2343313A1/en not_active Withdrawn
- 2005-05-16 IN IN290KON2015 patent/IN2015KN00290A/en unknown
- 2005-05-16 JP JP2007512595A patent/JP2008506364A/ja not_active Withdrawn
- 2005-05-16 CA CA002566632A patent/CA2566632A1/en not_active Abandoned
- 2005-05-16 EP EP10190381A patent/EP2351773A1/en not_active Withdrawn
- 2005-05-16 CN CNA2005800238288A patent/CN1997663A/zh active Pending
- 2005-05-16 WO PCT/IB2005/001775 patent/WO2005111066A2/en not_active Ceased
- 2005-05-16 BR BRPI0511118-8A patent/BRPI0511118A/pt not_active Application Discontinuation
- 2005-05-16 EP EP05748150A patent/EP1745067A2/en not_active Withdrawn
- 2005-05-16 EP EP10190390A patent/EP2351774A1/en not_active Withdrawn
- 2005-05-16 US US11/596,557 patent/US7749518B2/en not_active Expired - Fee Related
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2010
- 2010-05-25 US US12/800,898 patent/US8124098B2/en not_active Expired - Fee Related
-
2011
- 2011-07-29 JP JP2011166505A patent/JP2012000112A/ja active Pending
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2012
- 2012-01-24 US US13/357,394 patent/US20120148615A1/en not_active Abandoned
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2014
- 2014-04-29 US US14/264,972 patent/US9102729B2/en not_active Expired - Fee Related
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