JP2011511786A5 - - Google Patents
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- Publication number
- JP2011511786A5 JP2011511786A5 JP2010545576A JP2010545576A JP2011511786A5 JP 2011511786 A5 JP2011511786 A5 JP 2011511786A5 JP 2010545576 A JP2010545576 A JP 2010545576A JP 2010545576 A JP2010545576 A JP 2010545576A JP 2011511786 A5 JP2011511786 A5 JP 2011511786A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- composition
- treatment
- value
- degarelix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000002966 serum Anatomy 0.000 claims 13
- 102000002260 Alkaline Phosphatase Human genes 0.000 claims 11
- 108020004774 Alkaline Phosphatase Proteins 0.000 claims 11
- 108010052004 acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide Proteins 0.000 claims 11
- MEUCPCLKGZSHTA-XYAYPHGZSA-N degarelix Chemical compound C([C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CC=1C=CC(NC(=O)[C@H]2NC(=O)NC(=O)C2)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](CC=1C=NC=CC=1)NC(=O)[C@@H](CC=1C=CC(Cl)=CC=1)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(C)=O)C1=CC=C(NC(N)=O)C=C1 MEUCPCLKGZSHTA-XYAYPHGZSA-N 0.000 claims 11
- 229960002272 degarelix Drugs 0.000 claims 11
- 238000012423 maintenance Methods 0.000 claims 5
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 4
- 208000010658 metastatic prostate carcinoma Diseases 0.000 claims 4
- 206010060862 Prostate cancer Diseases 0.000 claims 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 3
- 230000007423 decrease Effects 0.000 claims 3
- 102000001554 Hemoglobins Human genes 0.000 claims 2
- 108010054147 Hemoglobins Proteins 0.000 claims 2
- 230000002250 progressing effect Effects 0.000 claims 2
- 229960003604 testosterone Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2774108P | 2008-02-11 | 2008-02-11 | |
| US61/027,741 | 2008-02-11 | ||
| EP08250703 | 2008-02-29 | ||
| EP08250703.9 | 2008-02-29 | ||
| US14795609P | 2009-01-28 | 2009-01-28 | |
| US61/147,956 | 2009-01-28 | ||
| PCT/IB2009/000370 WO2009101533A1 (en) | 2008-02-11 | 2009-02-10 | Treatment of metastatic stage prostate cancer with degarelix |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014087895A Division JP6254042B2 (ja) | 2008-02-11 | 2014-04-22 | 転移期前立腺癌を治療する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011511786A JP2011511786A (ja) | 2011-04-14 |
| JP2011511786A5 true JP2011511786A5 (https=) | 2012-03-22 |
| JP5876652B2 JP5876652B2 (ja) | 2016-03-02 |
Family
ID=39718285
Family Applications (12)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545576A Active JP5876652B2 (ja) | 2008-02-11 | 2009-02-10 | 転移期前立腺癌を治療する方法 |
| JP2010545575A Active JP5924866B2 (ja) | 2008-02-11 | 2009-02-10 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2014051197A Active JP6189234B2 (ja) | 2008-02-11 | 2014-03-14 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2014087895A Active JP6254042B2 (ja) | 2008-02-11 | 2014-04-22 | 転移期前立腺癌を治療する方法 |
| JP2016095555A Pending JP2016193910A (ja) | 2008-02-11 | 2016-05-11 | 転移期前立腺癌を治療する方法 |
| JP2016099437A Pending JP2016216455A (ja) | 2008-02-11 | 2016-05-18 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2017185676A Active JP6618967B2 (ja) | 2008-02-11 | 2017-09-27 | 転移期前立腺癌を治療する方法 |
| JP2022109616A Active JP7400029B2 (ja) | 2008-02-11 | 2022-07-07 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2022142833A Pending JP2022184898A (ja) | 2008-02-11 | 2022-09-08 | 転移期前立腺癌を治療する方法 |
| JP2023206150A Pending JP2024028869A (ja) | 2008-02-11 | 2023-12-06 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2025106071A Pending JP2025160167A (ja) | 2008-02-11 | 2025-06-24 | 転移期前立腺癌を治療する方法 |
| JP2025194876A Pending JP2026027448A (ja) | 2008-02-11 | 2025-11-14 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
Family Applications After (11)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545575A Active JP5924866B2 (ja) | 2008-02-11 | 2009-02-10 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2014051197A Active JP6189234B2 (ja) | 2008-02-11 | 2014-03-14 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2014087895A Active JP6254042B2 (ja) | 2008-02-11 | 2014-04-22 | 転移期前立腺癌を治療する方法 |
| JP2016095555A Pending JP2016193910A (ja) | 2008-02-11 | 2016-05-11 | 転移期前立腺癌を治療する方法 |
| JP2016099437A Pending JP2016216455A (ja) | 2008-02-11 | 2016-05-18 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2017185676A Active JP6618967B2 (ja) | 2008-02-11 | 2017-09-27 | 転移期前立腺癌を治療する方法 |
| JP2022109616A Active JP7400029B2 (ja) | 2008-02-11 | 2022-07-07 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2022142833A Pending JP2022184898A (ja) | 2008-02-11 | 2022-09-08 | 転移期前立腺癌を治療する方法 |
| JP2023206150A Pending JP2024028869A (ja) | 2008-02-11 | 2023-12-06 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2025106071A Pending JP2025160167A (ja) | 2008-02-11 | 2025-06-24 | 転移期前立腺癌を治療する方法 |
| JP2025194876A Pending JP2026027448A (ja) | 2008-02-11 | 2025-11-14 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (17) | US8841081B2 (https=) |
| EP (7) | EP2650012B1 (https=) |
| JP (12) | JP5876652B2 (https=) |
| KR (8) | KR101542480B1 (https=) |
| CN (4) | CN103990107A (https=) |
| AU (2) | AU2009213751B2 (https=) |
| BR (2) | BRPI0908127A2 (https=) |
| CA (3) | CA2714445C (https=) |
| CY (3) | CY1115561T1 (https=) |
| DK (3) | DK2249859T3 (https=) |
| EA (4) | EA036695B1 (https=) |
| ES (3) | ES2532709T3 (https=) |
| HK (1) | HK1198243A1 (https=) |
| HR (3) | HRP20140665T1 (https=) |
| IL (3) | IL207295A (https=) |
| JO (1) | JOP20090061B1 (https=) |
| MX (2) | MX2010008816A (https=) |
| NZ (4) | NZ587057A (https=) |
| PL (3) | PL2249859T3 (https=) |
| PT (3) | PT2249859E (https=) |
| RU (2) | RU2504394C2 (https=) |
| SI (3) | SI2249859T1 (https=) |
| TW (2) | TWI442932B (https=) |
| WO (2) | WO2009101530A1 (https=) |
| ZA (1) | ZA201005697B (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| JO3525B1 (ar) * | 2008-02-11 | 2020-07-05 | Ferring Int Center Sa | علاج سرطان البروستاتا في المرحلة النقيلية بدواء ديجاريليكس |
| TWI442932B (zh) * | 2008-02-11 | 2014-07-01 | Ferring Int Ct Sa | 以ＧｎＲＨ拮抗劑治療攝護腺癌的方法 |
| EP2424503B1 (en) * | 2009-05-01 | 2017-07-05 | Ferring BV | Composition for the treatment of prostate cancer |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| FR2964323B1 (fr) * | 2010-09-08 | 2012-11-09 | Jean Pierre Raynaud | Utilisation de la testosterone chez un patient en deficit androgenique et atteint d'un cancer de la prostate |
| PT2632934T (pt) | 2010-10-27 | 2017-01-06 | Ferring Bv | Processo para o fabrico de degarelix e seus intermediários |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| BR112013023050A8 (pt) * | 2011-03-09 | 2018-09-25 | G Pestell Richard | antagonista de ccr5, método para determinar se um indivíduo humano tendo câncer de próstata está sofrendo de ou sob o risco de desenvolver metástase, para identificar um antagonista de ccr5, método para determinar se um indivíduo humano tendo câncer de próstata está sofrendo de ou sob o risco de desenvolver metástase, para identificar um composto candidato, para produzir in vitro células epiteliais primárias, para diagnosticar câncer de próstata, para selecionar um tratamento para um indivíduo tendo um câncer/tumor de próstata, linhagem de célula, e, modelo animal |
| CN102204889B (zh) * | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| WO2013104745A1 (en) * | 2012-01-13 | 2013-07-18 | Ferring Bv | Pharmaceutical composition |
| AU2013262977A1 (en) | 2012-05-14 | 2015-01-22 | Prostagene, Llc | Using modulators of CCR5 for treating cancer |
| SG11201407679PA (en) | 2012-06-01 | 2014-12-30 | Ferring Bv | Manufacture of degarelix |
| SG11201501870RA (en) | 2012-09-26 | 2015-04-29 | Aragon Pharmaceuticals Inc | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
| AR092707A1 (es) | 2012-09-28 | 2015-04-29 | Takeda Pharmaceuticals Co | Metodo de produccion de derivado de tienopirimidina |
| US10881659B2 (en) | 2013-03-15 | 2021-01-05 | Abbvie Inc. | Methods of treating heavy menstrual bleeding |
| WO2014186608A1 (en) * | 2013-05-15 | 2014-11-20 | Adverse Events, Inc. | System and method for surveillance and evaluation of safety risks associated with medical interventions |
| EP3185881B1 (en) * | 2014-08-26 | 2022-03-09 | Betanien Hospital | Methods, agents and compositions for treatment of inflammatory conditions |
| JP6941565B2 (ja) * | 2015-05-12 | 2021-09-29 | ドレクセル ユニバーシティ | がん転移を処置または防止するのに有用な化合物および組成物、ならびにこれらの使用法 |
| MA46361A (fr) | 2016-09-30 | 2021-03-31 | Myovant Sciences Gmbh | Traitement du cancer de la prostate |
| JP6990717B2 (ja) * | 2017-01-30 | 2022-02-03 | アンテヴ リミテッド | 少なくとも１種のｇｎｒｈアンタゴニストを含む組成物 |
| AU2018351714A1 (en) | 2017-10-16 | 2020-04-30 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
| CN112261942A (zh) | 2018-04-19 | 2021-01-22 | 艾伯维公司 | 治疗重度月经出血的方法 |
| JP2021532160A (ja) * | 2018-08-01 | 2021-11-25 | アッヴィ・インコーポレイテッド | エラゴリックスに関する投与計画 |
| RU2731002C1 (ru) * | 2019-10-22 | 2020-08-26 | Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) | Способ лечения рака предстательной железы |
| CN116407494B (zh) * | 2023-03-02 | 2024-07-09 | 山东大学齐鲁医院 | 一种醋酸地加瑞克注射液及其制备方法、用途 |
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| TWI442932B (zh) | 2008-02-11 | 2014-07-01 | Ferring Int Ct Sa | 以ＧｎＲＨ拮抗劑治療攝護腺癌的方法 |
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| EP2424503B1 (en) | 2009-05-01 | 2017-07-05 | Ferring BV | Composition for the treatment of prostate cancer |
| TW201043221A (en) | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| WO2011066386A1 (en) | 2009-11-25 | 2011-06-03 | Novetide, Ltd. | Process for production of degarelix |
| IT1399892B1 (it) | 2010-03-15 | 2013-05-09 | Spi Tecno Srl | Sistema per l illuminazione pubblica |
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| PT2632934T (pt) | 2010-10-27 | 2017-01-06 | Ferring Bv | Processo para o fabrico de degarelix e seus intermediários |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| CN102204889B (zh) | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| EP2731607B1 (en) | 2011-07-15 | 2017-10-11 | Ferring B.V. | Method for timing a colonoscopy wherein a picosulate composition is administered |
| SG11201407679PA (en) | 2012-06-01 | 2014-12-30 | Ferring Bv | Manufacture of degarelix |
-
2009
- 2009-02-09 TW TW098104075A patent/TWI442932B/zh active
- 2009-02-09 TW TW098104073A patent/TWI539959B/zh active
- 2009-02-09 JO JOP/2009/0061A patent/JOP20090061B1/ar active
- 2009-02-10 EP EP13168404.5A patent/EP2650012B1/en not_active Revoked
- 2009-02-10 EA EA201300741A patent/EA036695B1/ru not_active IP Right Cessation
- 2009-02-10 ES ES12165896.7T patent/ES2532709T3/es active Active
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