JP2011506422A5 - - Google Patents

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Publication number
JP2011506422A5
JP2011506422A5 JP2010537542A JP2010537542A JP2011506422A5 JP 2011506422 A5 JP2011506422 A5 JP 2011506422A5 JP 2010537542 A JP2010537542 A JP 2010537542A JP 2010537542 A JP2010537542 A JP 2010537542A JP 2011506422 A5 JP2011506422 A5 JP 2011506422A5
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JP
Japan
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seq
antibody
variable region
chain variable
autoimmune
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JP2010537542A
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English (en)
Japanese (ja)
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JP2011506422A (ja
JP5745274B2 (ja
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Priority claimed from PCT/IB2008/005011 external-priority patent/WO2010055366A2/en
Publication of JP2011506422A publication Critical patent/JP2011506422A/ja
Publication of JP2011506422A5 publication Critical patent/JP2011506422A5/ja
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Publication of JP5745274B2 publication Critical patent/JP5745274B2/ja
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JP2010537542A 2007-12-07 2008-12-08 抗ヒトｉｌ−２１モノクローナル抗体 Active JP5745274B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1232907P 2007-12-07 2007-12-07
US61/012,329 2007-12-07
PCT/IB2008/005011 WO2010055366A2 (en) 2007-12-07 2008-12-08 Anti-human il-21 monoclonal antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014036592A Division JP5848384B2 (ja) 2007-12-07 2014-02-27 抗ヒトｉｌ−２１モノクローナル抗体

Publications (3)

Publication Number Publication Date
JP2011506422A JP2011506422A (ja) 2011-03-03
JP2011506422A5 true JP2011506422A5 (enExample) 2011-12-01
JP5745274B2 JP5745274B2 (ja) 2015-07-08

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ID=40899470

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010537542A Active JP5745274B2 (ja) 2007-12-07 2008-12-08 抗ヒトｉｌ−２１モノクローナル抗体
JP2014036592A Active JP5848384B2 (ja) 2007-12-07 2014-02-27 抗ヒトｉｌ−２１モノクローナル抗体
JP2015230496A Active JP6027668B2 (ja) 2007-12-07 2015-11-26 抗ヒトｉｌ−２１モノクローナル抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2014036592A Active JP5848384B2 (ja) 2007-12-07 2014-02-27 抗ヒトｉｌ−２１モノクローナル抗体
JP2015230496A Active JP6027668B2 (ja) 2007-12-07 2015-11-26 抗ヒトｉｌ−２１モノクローナル抗体

Country Status (18)

Country Link
US (5) US7883700B2 (enExample)
EP (3) EP2217268B1 (enExample)
JP (3) JP5745274B2 (enExample)
KR (2) KR101615215B1 (enExample)
CN (2) CN102027011B (enExample)
AU (1) AU2008364115B2 (enExample)
BR (1) BRPI0821168B8 (enExample)
CA (2) CA2910933C (enExample)
DK (1) DK2217268T3 (enExample)
ES (2) ES2584237T3 (enExample)
HU (1) HUE027828T2 (enExample)
IL (2) IL205976A (enExample)
MX (1) MX2010006181A (enExample)
PL (1) PL2217268T3 (enExample)
PT (1) PT2217268T (enExample)
RU (1) RU2504552C2 (enExample)
WO (1) WO2010055366A2 (enExample)
ZA (1) ZA201004046B (enExample)

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EP2217268B1 (en) 2007-12-07 2016-05-04 ZymoGenetics, Inc. Anti-human il-21 monoclonal antibodies
EP2596023A4 (en) * 2010-07-20 2014-03-05 Beth Israel Hospital COMPOSITIONS AND METHODS FOR IL-6 AND IL-21 ANTAGONISTS
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US20140178395A1 (en) * 2012-12-21 2014-06-26 Novo Nordisk A/S Treatment of nephropathy
EP2746293A1 (en) 2012-12-21 2014-06-25 Novo Nordisk A/S Anti-IL21 antibodies for use in the treatment of cardiovascular diseases
CN105579470B (zh) * 2013-06-27 2021-05-25 莫纳什大学 Il-21结合蛋白和其用途
CN103487572B (zh) * 2013-10-08 2017-03-29 北京大学人民医院 滤泡辅助性T淋巴细胞(Tfh)在自身免疫性疾病病情预警中的应用
CN104721820A (zh) * 2013-12-24 2015-06-24 信达生物制药(苏州)有限公司 双特异性单克隆抗体在治疗葡萄膜炎中的用途
WO2015132241A1 (en) * 2014-03-03 2015-09-11 Novo Nordisk A/S Treatment of inflammatory diseases
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MA39821B1 (fr) * 2014-04-08 2020-09-30 Boston Pharmaceuticals Inc Molécules de liaison spécifiques de l'il-21 et leurs utilisations
DK3139948T3 (da) * 2014-05-07 2020-05-25 Novo Nordisk As Behandling af type 1 diabetes under anvendelse af glp-1 og anti-il-21
WO2015169789A1 (en) * 2014-05-07 2015-11-12 Novo Nordisk A/S Treatment of diabetes type 1 using glp-1 and anti-il-21
RU2609627C2 (ru) 2014-09-26 2017-02-02 Закрытое Акционерное Общество "Биокад" Высокоаффинные и агрегационно стабильные антитела на основе вариабельных доменов vl и производного vhh
CA2971508A1 (en) * 2014-12-19 2016-06-23 Mabtech Ab Composition, kit and method for inhibition of il-21 mediated activation of human cells
WO2016094962A1 (en) 2014-12-19 2016-06-23 Monash University Il-21 antibodies
WO2017172509A1 (en) 2016-03-31 2017-10-05 Eli Lilly And Company Il-21 antibodies and uses thereof
WO2018045273A2 (en) * 2016-09-02 2018-03-08 The Brigham And Women's Hospital, Inc. Compositions and methods for treating neoplasias
JP6952295B2 (ja) * 2016-09-09 2021-10-20 国立大学法人金沢大学 ヒト抗ｈｌａモノクローナル抗体の作製方法
ES2910969T3 (es) 2017-08-03 2022-05-17 Amgen Inc Muteínas de interleucina-21 y métodos de tratamiento
TW201930344A (zh) 2018-01-12 2019-08-01 美商安進公司 抗ｐｄ-１抗體及治療方法
WO2021119482A1 (en) 2019-12-13 2021-06-17 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
EP4178605A1 (en) * 2020-07-13 2023-05-17 Transgene Treatment of immune depression
CN118370816A (zh) * 2024-03-22 2024-07-23 中日友好医院(中日友好临床医学研究所) Il-2/抗il-2抗体免疫复合物的应用
WO2025257327A1 (en) 2024-06-13 2025-12-18 Almirall, S.A. Therapeutic approaches for the management of hidradenitis suppurativa

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