PL3139948T3 - Leczenie cukrzycy z zastosowaniem glp-1 i anty-il-21 - Google Patents

Leczenie cukrzycy z zastosowaniem glp-1 i anty-il-21

Info

Publication number
PL3139948T3
PL3139948T3 PL15720982T PL15720982T PL3139948T3 PL 3139948 T3 PL3139948 T3 PL 3139948T3 PL 15720982 T PL15720982 T PL 15720982T PL 15720982 T PL15720982 T PL 15720982T PL 3139948 T3 PL3139948 T3 PL 3139948T3
Authority
PL
Poland
Prior art keywords
glp
treatment
diabetes type
diabetes
type
Prior art date
Application number
PL15720982T
Other languages
English (en)
Inventor
Ken COPPIETERS
Matthias Von Herrath
Tamar BOURSALIAN
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of PL3139948T3 publication Critical patent/PL3139948T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL15720982T 2014-05-07 2015-05-05 Leczenie cukrzycy z zastosowaniem glp-1 i anty-il-21 PL3139948T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461989841P 2014-05-07 2014-05-07
EP14169596 2014-05-23
EP14189732 2014-10-21
PCT/EP2015/059811 WO2015169789A1 (en) 2014-05-07 2015-05-05 Treatment of diabetes type 1 using glp-1 and anti-il-21
EP15720982.6A EP3139948B1 (en) 2014-05-07 2015-05-05 Treatment of diabetes type 1 using glp-1 and anti-il-21

Publications (1)

Publication Number Publication Date
PL3139948T3 true PL3139948T3 (pl) 2020-08-10

Family

ID=54392180

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15720982T PL3139948T3 (pl) 2014-05-07 2015-05-05 Leczenie cukrzycy z zastosowaniem glp-1 i anty-il-21

Country Status (9)

Country Link
US (1) US10105442B2 (pl)
EP (1) EP3139948B1 (pl)
JP (1) JP6672175B2 (pl)
CN (1) CN106999553B (pl)
PL (1) PL3139948T3 (pl)
RS (1) RS60316B1 (pl)
SI (1) SI3139948T1 (pl)
TW (1) TWI668010B (pl)
WO (1) WO2015169789A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017149109A1 (en) * 2016-03-04 2017-09-08 Novo Nordisk A/S Liraglutide in diabetic foot ulcer
US12012441B2 (en) 2020-10-26 2024-06-18 Neptune Biosciences Llc Engineered human IL-21 cytokines and methods for using the same
WO2025257327A1 (en) 2024-06-13 2025-12-18 Almirall, S.A. Therapeutic approaches for the management of hidradenitis suppurativa

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ300837B6 (cs) 1996-08-30 2009-08-26 Novo Nordisk A/S Deriváty GLP-1(7-37) nebo jeho analogy, farmaceutický prostredek je obsahující a jejich použití
US7186683B2 (en) 2000-09-18 2007-03-06 Sanos Bioscience A/S Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders
WO2003002136A2 (en) 2001-06-28 2003-01-09 Novo Nordisk A/S Stable formulation of modified glp-1
EP1432431B1 (en) 2001-10-04 2017-05-10 Genetics Institute LLC Methods and compositions for modulating interleukin-21 activity
EP1515749B1 (en) * 2002-06-14 2012-08-15 Novo Nordisk A/S Combined use of a modulator of cd3 and a glp-1 compound
WO2005023291A2 (en) * 2003-09-11 2005-03-17 Novo Nordisk A/S Use of glp1-agonists in the treatment of patients with type i diabetes
CN100444898C (zh) * 2003-09-19 2008-12-24 诺沃挪第克公司 治疗肽的清蛋白结合型衍生物
DE602004031455D1 (de) * 2003-12-09 2011-03-31 Novo Nordisk As Regulierung der nahrungspräferenz mit glp-1-agonisten
EP1841448A2 (en) 2004-12-30 2007-10-10 Diakine Therapeutics, Inc. Pharmaceutical compositions and methods for restoring beta-cell mass and function
TWI362392B (en) 2005-03-18 2012-04-21 Novo Nordisk As Acylated glp-1 compounds
CA2609667C (en) 2005-05-25 2011-02-22 Curedm, Inc. Human proislet peptide, derivatives and analogs thereof, and methods of using same
MX2008001468A (es) * 2005-06-30 2008-04-07 Sod Conseils Rech Applic Composiciones farmaceuticas del peptido similar al glucagon-1.
WO2007016764A1 (en) 2005-08-06 2007-02-15 Qinghua Wang Composition and method for prevention and treatment of type i diabetes
JP5693817B2 (ja) * 2005-08-19 2015-04-01 アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc 糖尿病の治療法および体重の減少法
CN101291685A (zh) * 2005-08-19 2008-10-22 安米林药品公司 治疗糖尿病和降低体重的毒蜥外泌肽
US8084022B2 (en) * 2006-06-23 2011-12-27 Aegis Therapeutics, Llc Stabilizing alkylglycoside compositions and methods thereof
NZ574710A (en) * 2006-09-07 2012-02-24 Nycomed Gmbh Combination treatment comprising the PDE4 inhibitor Compound A ((2R,4aR, 10bR)6-(2,6-Dimethoxy-pyridin-3-yl)-9-ethoxy-8-methoxy-1 ,2,3,4,4a,10b-hexahydrophenanthridin-2-ol) for diabetes mellitus
US20100325744A1 (en) * 2007-05-31 2010-12-23 Genmab A/S Non-glycosylated recombinant monovalent antibodies
US8816047B2 (en) * 2007-08-30 2014-08-26 Cure DM Group Holdings, LLC Compositions and methods of using proislet peptides and analogs thereof
JP5476304B2 (ja) * 2007-09-05 2014-04-23 ノボ・ノルデイスク・エー／エス グルカゴン様ペプチド−１誘導体及びそれらの医薬用途
EP2217268B1 (en) * 2007-12-07 2016-05-04 ZymoGenetics, Inc. Anti-human il-21 monoclonal antibodies
WO2009137080A1 (en) * 2008-05-07 2009-11-12 Merrion Research Iii Limited Compositions of gnrh related compounds and processes of preparation
WO2009158704A2 (en) * 2008-06-27 2009-12-30 Duke University Therapeutic agents comprising elastin-like peptides
RU2537239C2 (ru) * 2009-11-13 2014-12-27 Санофи-Авентис Дойчланд Гмбх Фармацевтическая композиция, включающая агонист glp-1, инсулин и метионин
EP2460527A1 (en) * 2010-01-21 2012-06-06 Sanofi Pharmaceutical composition for treating a metabolic syndrome
JP2013520208A (ja) 2010-02-24 2013-06-06 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ 自己免疫疾患の診断、予後判定、及び処置法
CN103443124A (zh) * 2011-01-17 2013-12-11 诺沃—诺迪斯克有限公司 Il-21配体
KR20140027307A (ko) * 2011-05-05 2014-03-06 노보자임스 바이오파마 디케이 에이/에스 알부민 변이체
JP2014518198A (ja) * 2011-05-31 2014-07-28 ノヴォ ノルディスク アー／エス Ｉｌ−２１のエピトープおよびｉｌ−２１リガンド
US20140178396A1 (en) 2012-12-21 2014-06-26 Novo Nordisk A/S Treatment of cardiovascular diseases
US20140178395A1 (en) 2012-12-21 2014-06-26 Novo Nordisk A/S Treatment of nephropathy

Also Published As

Publication number Publication date
TW201625289A (zh) 2016-07-16
EP3139948A1 (en) 2017-03-15
JP6672175B2 (ja) 2020-03-25
CN106999553A (zh) 2017-08-01
CN106999553B (zh) 2021-11-26
TWI668010B (zh) 2019-08-11
EP3139948B1 (en) 2020-03-04
JP2017514860A (ja) 2017-06-08
US20170043014A1 (en) 2017-02-16
RS60316B1 (sr) 2020-07-31
SI3139948T1 (sl) 2020-07-31
US10105442B2 (en) 2018-10-23
WO2015169789A1 (en) 2015-11-12

Similar Documents

Publication Publication Date Title
SMT201900175T1 (it) Composti di diidrobenzofurano utili nel trattamento di diabete e obesita'
GB201403093D0 (en) Therapeutic compounds and their use
ZA201806637B (en) Glucagon and glp-1 co-agonists for the treatment of obesity
IL246757B (en) New insulin histories and their medical uses
SMT202100668T1 (it) Trattamento dell'ipoglicemia post-bariatrica con antagonisti del glp-1
ZA201608281B (en) Ppar compounds for use in the treatment of fibrotic diseases.
IL283335B (en) Dihydropyrimidine-2-one compounds and their medical use
GB201612165D0 (en) Combinations for the treatment of type 2 diabetes
IL254496A0 (en) Treatment of type 2 diabetes patients
IL254500A0 (en) Treatment of patients with type 2 diabetes
GB201707207D0 (en) Treatment of type 1 diabetes
IL252899A0 (en) Cross-linked polydiallyamine copolymers for the treatment of type 2 diabetes
PL3139948T3 (pl) Leczenie cukrzycy z zastosowaniem glp-1 i anty-il-21
GB201403996D0 (en) Traditional chinese medicine composition for the treatment of diabetes
IL250666A0 (en) A peptide for the treatment of diabetes mellitus type 2 and its complications
GB201513543D0 (en) Compositions for use in the treatment of diabetes
PT3139948T (pt) Tratamento de diabetes usando glp-1 e anti-il-21
GB201418541D0 (en) Materials for use with general hyperthermia treatment
SG10201400823PA (en) Therapeutic methods and compositions for treating diabetes
GB201417777D0 (en) Novel compounds and therapeutic uses thereof
ZA201404780B (en) Composition for use in treatment of diabetes
GB201410387D0 (en) Compounds and their therapeutic use
GB201403496D0 (en) Compounds and their therapeutic use