JP2019162105A5 - - Google Patents
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- JP2019162105A5 JP2019162105A5 JP2019046955A JP2019046955A JP2019162105A5 JP 2019162105 A5 JP2019162105 A5 JP 2019162105A5 JP 2019046955 A JP2019046955 A JP 2019046955A JP 2019046955 A JP2019046955 A JP 2019046955A JP 2019162105 A5 JP2019162105 A5 JP 2019162105A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- isolated antibody
- amino acid
- variable domain
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 18
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 12
- 108060003951 Immunoglobulin Proteins 0.000 claims 9
- 102000018358 immunoglobulin Human genes 0.000 claims 9
- 238000006467 substitution reaction Methods 0.000 claims 6
- 208000023275 Autoimmune disease Diseases 0.000 claims 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 229940127557 pharmaceutical product Drugs 0.000 claims 3
- 206010021245 Idiopathic thrombocytopenic purpura Diseases 0.000 claims 2
- 102100026120 IgG receptor FcRn large subunit p51 Human genes 0.000 claims 2
- 101710177940 IgG receptor FcRn large subunit p51 Proteins 0.000 claims 2
- 208000031981 Thrombocytopenic Idiopathic Purpura Diseases 0.000 claims 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 2
- 201000003710 autoimmune thrombocytopenic purpura Diseases 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 206010028417 myasthenia gravis Diseases 0.000 claims 2
- 108010068617 neonatal Fc receptor Proteins 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 2
- 208000003343 Antiphospholipid Syndrome Diseases 0.000 claims 1
- 208000032116 Autoimmune Experimental Encephalomyelitis Diseases 0.000 claims 1
- 206010064539 Autoimmune myocarditis Diseases 0.000 claims 1
- 208000023328 Basedow disease Diseases 0.000 claims 1
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 claims 1
- 208000033222 Biliary cirrhosis primary Diseases 0.000 claims 1
- 208000015943 Coeliac disease Diseases 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 208000006313 Delayed Hypersensitivity Diseases 0.000 claims 1
- 208000007882 Gastritis Diseases 0.000 claims 1
- 208000024869 Goodpasture syndrome Diseases 0.000 claims 1
- 208000015023 Graves' disease Diseases 0.000 claims 1
- 208000035895 Guillain-Barré syndrome Diseases 0.000 claims 1
- 208000030836 Hashimoto thyroiditis Diseases 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 208000011200 Kawasaki disease Diseases 0.000 claims 1
- 206010049567 Miller Fisher syndrome Diseases 0.000 claims 1
- 206010034277 Pemphigoid Diseases 0.000 claims 1
- 241000721454 Pemphigus Species 0.000 claims 1
- 208000012654 Primary biliary cholangitis Diseases 0.000 claims 1
- 208000003782 Raynaud disease Diseases 0.000 claims 1
- 208000012322 Raynaud phenomenon Diseases 0.000 claims 1
- 208000021386 Sjogren Syndrome Diseases 0.000 claims 1
- 208000006045 Spondylarthropathies Diseases 0.000 claims 1
- 201000009594 Systemic Scleroderma Diseases 0.000 claims 1
- 206010042953 Systemic sclerosis Diseases 0.000 claims 1
- 206010060872 Transplant failure Diseases 0.000 claims 1
- 206010047642 Vitiligo Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 208000012997 experimental autoimmune encephalomyelitis Diseases 0.000 claims 1
- 208000006454 hepatitis Diseases 0.000 claims 1
- 231100000283 hepatitis Toxicity 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 201000008350 membranous glomerulonephritis Diseases 0.000 claims 1
- 208000001725 mucocutaneous lymph node syndrome Diseases 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 208000004235 neutropenia Diseases 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 208000005987 polymyositis Diseases 0.000 claims 1
- 201000000306 sarcoidosis Diseases 0.000 claims 1
- 201000005671 spondyloarthropathy Diseases 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 201000008827 tuberculosis Diseases 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022075914A JP2022115960A (ja) | 2008-04-25 | 2022-05-02 | FcRnに対する抗体及びその使用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4815208P | 2008-04-25 | 2008-04-25 | |
| US61/048,152 | 2008-04-25 | ||
| US4850008P | 2008-04-28 | 2008-04-28 | |
| US61/048,500 | 2008-04-28 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016155218A Division JP6499132B2 (ja) | 2008-04-25 | 2016-08-08 | FcRnに対する抗体及びその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022075914A Division JP2022115960A (ja) | 2008-04-25 | 2022-05-02 | FcRnに対する抗体及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019162105A JP2019162105A (ja) | 2019-09-26 |
| JP2019162105A5 true JP2019162105A5 (enExample) | 2019-11-07 |
Family
ID=41203902
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011506301A Active JP6106854B2 (ja) | 2008-04-25 | 2009-04-24 | FcRnに対する抗体及びその使用 |
| JP2015027638A Active JP5989159B2 (ja) | 2008-04-25 | 2015-02-16 | FcRnに対する抗体及びその使用 |
| JP2016155218A Active JP6499132B2 (ja) | 2008-04-25 | 2016-08-08 | FcRnに対する抗体及びその使用 |
| JP2019046955A Pending JP2019162105A (ja) | 2008-04-25 | 2019-03-14 | FcRnに対する抗体及びその使用 |
| JP2022075914A Pending JP2022115960A (ja) | 2008-04-25 | 2022-05-02 | FcRnに対する抗体及びその使用 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011506301A Active JP6106854B2 (ja) | 2008-04-25 | 2009-04-24 | FcRnに対する抗体及びその使用 |
| JP2015027638A Active JP5989159B2 (ja) | 2008-04-25 | 2015-02-16 | FcRnに対する抗体及びその使用 |
| JP2016155218A Active JP6499132B2 (ja) | 2008-04-25 | 2016-08-08 | FcRnに対する抗体及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022075914A Pending JP2022115960A (ja) | 2008-04-25 | 2022-05-02 | FcRnに対する抗体及びその使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (10) | US8273351B2 (enExample) |
| EP (3) | EP2310415B8 (enExample) |
| JP (5) | JP6106854B2 (enExample) |
| KR (4) | KR102072896B1 (enExample) |
| CN (3) | CN108467431A (enExample) |
| AU (1) | AU2009238605B2 (enExample) |
| BR (2) | BRPI0910622A2 (enExample) |
| CA (2) | CA3131470A1 (enExample) |
| ES (1) | ES2650804T3 (enExample) |
| HK (1) | HK1207089A1 (enExample) |
| IL (2) | IL208846A (enExample) |
| MX (1) | MX2010011679A (enExample) |
| NZ (1) | NZ589451A (enExample) |
| SG (3) | SG196839A1 (enExample) |
| TW (3) | TWI547287B (enExample) |
| WO (1) | WO2009131702A2 (enExample) |
| ZA (1) | ZA201007873B (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
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| BRPI0910622A2 (pt) | 2008-04-25 | 2020-03-10 | Dyax Corp. | ANTICORPOS CONTRA FcRn E USOS DOS MESMOS |
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| EP4011913A1 (en) | 2011-06-30 | 2022-06-15 | Chugai Seiyaku Kabushiki Kaisha | Heterodimerized polypeptide |
| JP6322411B2 (ja) | 2011-09-30 | 2018-05-09 | 中外製薬株式会社 | 複数の生理活性を有する抗原の消失を促進する抗原結合分子 |
| KR102528622B1 (ko) * | 2011-09-30 | 2023-05-04 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존성 결합 분자 라이브러리 |
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