JP2011502483A5 - - Google Patents
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- JP2011502483A5 JP2011502483A5 JP2010532232A JP2010532232A JP2011502483A5 JP 2011502483 A5 JP2011502483 A5 JP 2011502483A5 JP 2010532232 A JP2010532232 A JP 2010532232A JP 2010532232 A JP2010532232 A JP 2010532232A JP 2011502483 A5 JP2011502483 A5 JP 2011502483A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- amino acid
- homology
- sequences
- identity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98443007P | 2007-11-01 | 2007-11-01 | |
| US60/984,430 | 2007-11-01 | ||
| PCT/US2008/081721 WO2009058956A1 (en) | 2007-11-01 | 2008-10-30 | Signal sequences and co-expressed chaperones for improving protein production in a host cell |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013009289A Division JP2013121354A (ja) | 2007-11-01 | 2013-01-22 | 宿主細胞におけるタンパク質生産を改善するためのシグナル配列及び共発現したシャペロン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011502483A JP2011502483A (ja) | 2011-01-27 |
| JP2011502483A5 true JP2011502483A5 (enExample) | 2013-03-21 |
| JP5252746B2 JP5252746B2 (ja) | 2013-07-31 |
Family
ID=40304979
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010532232A Expired - Fee Related JP5252746B2 (ja) | 2007-11-01 | 2008-10-30 | 宿主細胞におけるタンパク質生産を改善するためのシグナル配列及び共発現したシャペロン |
| JP2013009289A Pending JP2013121354A (ja) | 2007-11-01 | 2013-01-22 | 宿主細胞におけるタンパク質生産を改善するためのシグナル配列及び共発現したシャペロン |
| JP2014200112A Withdrawn JP2015027308A (ja) | 2007-11-01 | 2014-09-30 | 宿主細胞におけるタンパク質生産を改善するためのシグナル配列及び共発現したシャペロン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013009289A Pending JP2013121354A (ja) | 2007-11-01 | 2013-01-22 | 宿主細胞におけるタンパク質生産を改善するためのシグナル配列及び共発現したシャペロン |
| JP2014200112A Withdrawn JP2015027308A (ja) | 2007-11-01 | 2014-09-30 | 宿主細胞におけるタンパク質生産を改善するためのシグナル配列及び共発現したシャペロン |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20090221030A1 (enExample) |
| EP (1) | EP2203556A1 (enExample) |
| JP (3) | JP5252746B2 (enExample) |
| CN (1) | CN101842479A (enExample) |
| AU (1) | AU2008318644B2 (enExample) |
| BR (1) | BRPI0818273A2 (enExample) |
| CA (1) | CA2704548A1 (enExample) |
| CO (1) | CO6210760A2 (enExample) |
| MX (1) | MX2010004325A (enExample) |
| WO (1) | WO2009058956A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010075402A1 (en) | 2008-12-24 | 2010-07-01 | Danisco Us Inc. | Laccases and methods of use thereof at low temperature |
| PT2403809E (pt) | 2009-03-03 | 2015-10-13 | Danisco Us Inc | Método de descoloração oxidativa de corantes com perácido gerado por acção enzimática |
| FI20095615A0 (fi) * | 2009-06-02 | 2009-06-02 | Oulun Yliopisto | Menetelmä luonnollisesti laskostuneiden proteiinien tuottamiseksi prokaryootti-isännässä |
| CN103189564A (zh) | 2010-10-18 | 2013-07-03 | 丹尼斯科美国公司 | 使用漆酶体系对染色织物进行局部颜色修改 |
| EP2694647A1 (en) | 2011-04-06 | 2014-02-12 | Danisco US Inc. | Laccase variants having increased expression and/or activity |
| JP2012235767A (ja) * | 2011-04-27 | 2012-12-06 | Toyota Motor Corp | 変異トリコデルマ属微生物及びこれを用いたタンパク質の製造方法 |
| US9567596B2 (en) | 2012-01-05 | 2017-02-14 | Glykos Finland Oy | Protease deficient filamentous fungal cells and methods of use thereof |
| EP2808388B1 (en) * | 2012-01-23 | 2019-03-13 | AGC Inc. | Expression vector and method for producing protein |
| WO2013174927A1 (en) | 2012-05-23 | 2013-11-28 | Novartis International Pharmaceutical Limited | Production of fucosylated glycoproteins |
| US9993534B2 (en) * | 2013-03-12 | 2018-06-12 | Wisconsin Alumni Research Foundation | Method of treating fungal infection |
| JP2016523552A (ja) | 2013-07-10 | 2016-08-12 | ノバルティス アーゲー | 多重プロテアーゼ欠損糸状菌細胞及びその使用方法 |
| CN104694560A (zh) * | 2013-12-04 | 2015-06-10 | 中国科学院天津工业生物技术研究所 | 一种源于里氏木霉的二硫键异构酶基因Trpdi2及其用途 |
| SG10201809152QA (en) | 2014-04-17 | 2018-11-29 | Boehringer Ingelheim Rcv Gmbh | Recombinant host cell for expressing proteins of interest |
| KR102373954B1 (ko) | 2014-04-17 | 2022-03-14 | 베링거 인겔하임 에르체파우 게엠베하 운트 코 카게 | 보조 단백질을 과발현하도록 조작된 재조합 숙주세포 |
| AU2015293949B2 (en) | 2014-07-21 | 2019-07-25 | Teknologian Tutkimuskeskus Vtt Oy | Production of glycoproteins with mammalian-like N-glycans in filamentous fungi |
| JP2017525359A (ja) * | 2014-08-15 | 2017-09-07 | ダニスコ・ユーエス・インク | タンパク質の産生改善のための組成物及び方法 |
| US10526609B2 (en) * | 2016-08-01 | 2020-01-07 | Aduro Biotech, Inc. | Protein expression enhancer sequences and use thereof |
| WO2020002494A1 (en) * | 2018-06-27 | 2020-01-02 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Means and methods for increased protein expression by use of transcription factors |
| KR102138272B1 (ko) * | 2018-09-19 | 2020-07-28 | 주식회사 바이오앱 | BiP 단편을 포함하는 재조합 벡터 및 상기 벡터를 이용한 재조합 단백질의 제조 방법 |
| WO2021112540A1 (ko) * | 2019-12-02 | 2021-06-10 | 주식회사 엘지화학 | Cho 세포 유래 단백질 분비 인자 및 이를 포함하는 발현 벡터 |
| CN112501141A (zh) * | 2020-10-22 | 2021-03-16 | 重庆中元汇吉生物技术有限公司 | 一种增加人甲状腺过氧化物酶产量的试剂和表达方法 |
| CN112175977B (zh) * | 2020-10-30 | 2022-04-15 | 华中农业大学 | 一种米曲霉角蛋白酶基因及其表达载体与应用 |
| CN112391402B (zh) * | 2020-11-17 | 2023-03-28 | 华中科技大学 | 一种提高解脂耶氏酵母中目的蛋白表达水平的方法 |
| CN112409464B (zh) * | 2020-11-23 | 2022-04-22 | 江南大学 | 提高枯草芽孢杆菌重组蛋白胞外生产水平的信号肽突变体及应用 |
| EP4399295A1 (en) * | 2021-09-09 | 2024-07-17 | International N&H Denmark ApS | Over expression of foldases and chaperones improves protein production |
| CN113736817B (zh) * | 2021-10-08 | 2023-02-03 | 枣庄市杰诺生物酶有限公司 | 一种毕赤酵母中提高碱性脂肪酶分泌效率及酶活的方法 |
| CN117903294B (zh) * | 2024-03-19 | 2024-06-14 | 北京国科星联科技有限公司 | 一种发酵生产乳铁蛋白的马克斯克鲁维酵母及其构建方法与应用 |
| CN117903295B (zh) * | 2024-03-19 | 2024-05-31 | 北京国科星联科技有限公司 | 一种用于分泌表达乳铁蛋白的马克斯克鲁维酵母及其构建方法与应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2097180C (en) * | 1990-12-10 | 2007-08-14 | Timothy Fowler | Saccharification of cellulose by cloning and amplification of the .beta.-glucosidase gene of trichoderma reesei |
| EP0663010B1 (en) * | 1992-10-02 | 2000-08-09 | Research Corporation Technologies, Inc. | Methods for increasing secretion of overexpressed proteins |
| US5861271A (en) * | 1993-12-17 | 1999-01-19 | Fowler; Timothy | Cellulase enzymes and systems for their expressions |
| US6008029A (en) * | 1995-08-25 | 1999-12-28 | Novo Nordisk Biotech Inc. | Purified coprinus laccases and nucleic acids encoding the same |
| CN1151264C (zh) * | 1997-04-07 | 2004-05-26 | 尤尼利弗公司 | 农杆菌介导的霉菌特别是属于曲霉菌属的霉菌的转化 |
| EP1032655B1 (en) * | 1997-11-21 | 2005-06-29 | Novozymes A/S | Protease variants and compositions |
| US6268328B1 (en) * | 1998-12-18 | 2001-07-31 | Genencor International, Inc. | Variant EGIII-like cellulase compositions |
| EP1266018B1 (en) * | 2000-03-24 | 2008-05-07 | Genencor International, Inc. | Production of secreted proteins by recombinant eukaryotic cells |
| US6358733B1 (en) * | 2000-05-19 | 2002-03-19 | Apolife, Inc. | Expression of heterologous multi-domain proteins in yeast |
| JP2002065282A (ja) * | 2000-09-04 | 2002-03-05 | Iwate Prefecture | シイタケラッカーゼ遺伝子 |
| KR20120099303A (ko) * | 2003-11-06 | 2012-09-07 | 다니스코 유에스 인크. | 프로테아제 저해자 및 그 변이체의 사상균 내에서의 발현 |
| DK1680507T3 (da) * | 2003-11-06 | 2011-10-10 | Danisco Us Inc | Bakterieekspression af proteaseinhibitorer og varianter deraf |
| MXPA06013600A (es) * | 2004-05-27 | 2007-03-15 | Genencor Int | Alfa amilasas acidoestables con actividad hidrolizante de almidon granular y composiciones enzimaticas. |
| MX2007007862A (es) * | 2004-12-30 | 2007-08-17 | Genencor Int | Proteasas fungales acidas. |
| BRPI0721285A2 (pt) * | 2006-12-18 | 2014-03-25 | Danisco Us Inc Genencor Div | Mediadores de lacase e métodos de uso |
| EP2129685B1 (en) * | 2007-03-21 | 2013-11-20 | Danisco US Inc. | Over expression of foldases and chaperones improves protein production |
-
2008
- 2008-10-30 US US12/261,306 patent/US20090221030A1/en not_active Abandoned
- 2008-10-30 CA CA2704548A patent/CA2704548A1/en not_active Abandoned
- 2008-10-30 AU AU2008318644A patent/AU2008318644B2/en not_active Ceased
- 2008-10-30 JP JP2010532232A patent/JP5252746B2/ja not_active Expired - Fee Related
- 2008-10-30 EP EP08844940A patent/EP2203556A1/en not_active Withdrawn
- 2008-10-30 WO PCT/US2008/081721 patent/WO2009058956A1/en not_active Ceased
- 2008-10-30 BR BRPI0818273-6A2A patent/BRPI0818273A2/pt not_active IP Right Cessation
- 2008-10-30 CN CN200880114429A patent/CN101842479A/zh active Pending
- 2008-10-30 MX MX2010004325A patent/MX2010004325A/es active IP Right Grant
-
2010
- 2010-04-23 CO CO10048157A patent/CO6210760A2/es not_active Application Discontinuation
-
2013
- 2013-01-22 JP JP2013009289A patent/JP2013121354A/ja active Pending
-
2014
- 2014-09-30 JP JP2014200112A patent/JP2015027308A/ja not_active Withdrawn
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