|
US8343966B2
(en)
*
|
2008-01-11 |
2013-01-01 |
Novartis Ag |
Organic compounds
|
|
FR2945806B1
(fr)
*
|
2009-05-19 |
2013-04-05 |
Sanofi Aventis |
Nouveaux derives imidazo[1,2-a]pyridine,procede de preparation,medicaments,compositions pharmaceutiques et utilisation notamment comme inhibiteurs de met
|
|
KR20110039559A
(ko)
*
|
2008-07-18 |
2011-04-19 |
사노피-아벤티스 |
신규 이미다조[1,2-a]피리딘 유도체, 그의 제조 방법, 의약으로서의 그의 용도, 제약 조성물, 및 특히 met 억제제로서의 신규 용도
|
|
MX2011012037A
(es)
*
|
2009-05-13 |
2012-02-28 |
Amgen Inc |
Compuestos de heteroarilo como inhibidores de pikk.
|
|
CA2767091A1
(en)
*
|
2009-07-15 |
2011-01-20 |
Abbott Laboratories |
Pyrrolopyrazine inhibitors of kinases
|
|
UY33213A
(es)
|
2010-02-18 |
2011-09-30 |
Almirall Sa |
Derivados de pirazol como inhibidores de jak
|
|
US9073918B2
(en)
|
2010-05-20 |
2015-07-07 |
Takeda Pharmaceutical Company Limited |
Pyrazolo[4,3-b]pyridine-7-amine inhibitors of ALK5
|
|
CN102443009B
(zh)
*
|
2010-09-30 |
2014-04-16 |
山东轩竹医药科技有限公司 |
并环激酶抑制剂
|
|
EP2463289A1
(en)
|
2010-11-26 |
2012-06-13 |
Almirall, S.A. |
Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors
|
|
PE20140570A1
(es)
*
|
2011-07-01 |
2014-04-28 |
Bayer Ip Gmbh |
Pirrolotriazinas sustituidas con hidroximetilarilo y sus usos
|
|
EP2554544A1
(en)
|
2011-08-01 |
2013-02-06 |
Almirall, S.A. |
Pyridin-2(1h)-one derivatives as jak inhibitors
|
|
HK1203412A1
(en)
|
2011-12-28 |
2015-10-30 |
Global Blood Therapeutics, Inc. |
Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
|
|
ES2643403T3
(es)
|
2011-12-28 |
2017-11-22 |
Global Blood Therapeutics, Inc. |
Compuestos de benzaldehído sustituidos y métodos para su uso en el aumento de la oxigenación tisular
|
|
GB201205669D0
(en)
*
|
2012-03-30 |
2012-05-16 |
Agency Science Tech & Res |
Bicyclic heterocyclic derivatives as mnk2 and mnk2 modulators and uses thereof
|
|
US10280168B2
(en)
|
2012-03-30 |
2019-05-07 |
Agency For Science, Technology And Research |
Bicyclic heteroaryl derivatives as MNK1 and MNK2 modulators and uses thereof
|
|
ES2704744T3
(es)
|
2012-06-13 |
2019-03-19 |
Incyte Holdings Corp |
Compuestos tricíclicos sustituidos como inhibidores de FGFR
|
|
KR102092988B1
(ko)
*
|
2012-09-28 |
2020-03-25 |
벤더르빌트 유니버시티 |
선택성 bmp 저해제로써 융합된 헤테로 고리 화합물들
|
|
US9422279B2
(en)
|
2013-03-15 |
2016-08-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US20140274961A1
(en)
|
2013-03-15 |
2014-09-18 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US8952171B2
(en)
|
2013-03-15 |
2015-02-10 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US10266551B2
(en)
|
2013-03-15 |
2019-04-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US10100043B2
(en)
|
2013-03-15 |
2018-10-16 |
Global Blood Therapeutics, Inc. |
Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
|
|
WO2014150258A1
(en)
|
2013-03-15 |
2014-09-25 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US9458139B2
(en)
|
2013-03-15 |
2016-10-04 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US9604999B2
(en)
|
2013-03-15 |
2017-03-28 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US9802900B2
(en)
|
2013-03-15 |
2017-10-31 |
Global Blood Therapeutics, Inc. |
Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
|
|
MX379235B
(es)
|
2013-03-15 |
2025-03-11 |
Global Blood Therapeutics Inc |
Compuestos y sus usos para modular la hemoglobina.
|
|
CN105073728A
(zh)
|
2013-03-15 |
2015-11-18 |
全球血液疗法股份有限公司 |
化合物及其用于调节血红蛋白的用途
|
|
EA035095B1
(ru)
|
2013-04-19 |
2020-04-27 |
Инсайт Холдингс Корпорейшн |
Бициклические гетероциклы в качестве ингибиторов fgfr
|
|
WO2015031285A1
(en)
*
|
2013-08-27 |
2015-03-05 |
Global Blood Therapeutics, Inc. |
Crystalline 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde ansolvate salts
|
|
EA201992707A1
(ru)
|
2013-11-18 |
2020-06-30 |
Глобал Блад Терапьютикс, Инк. |
Соединения и их применения для модуляции гемоглобина
|
|
CN114181195A
(zh)
|
2014-02-07 |
2022-03-15 |
全球血液疗法股份有限公司 |
一种化合物的结晶多晶型物
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
MA41841A
(fr)
|
2015-03-30 |
2018-02-06 |
Global Blood Therapeutics Inc |
Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
|
|
WO2017024408A1
(en)
|
2015-08-11 |
2017-02-16 |
Neomed Institute |
Aryl-substituted dihydroquinolinones, their preparation and their use as pharmaceuticals
|
|
US10836742B2
(en)
|
2015-08-11 |
2020-11-17 |
Neomed Institute |
N-substituted bicyclic lactams, their preparation and their use as pharmaceuticals
|
|
CN108137539B
(zh)
|
2015-08-12 |
2022-01-11 |
尼奥迈德研究所 |
取代的苯并咪唑、它们的制备和它们作为药物的用途
|
|
US10501459B2
(en)
|
2015-10-21 |
2019-12-10 |
Neomed Institute |
Substituted imidazo[1,2-a]pyridines as bromodomain inhibitors
|
|
SG11201804647TA
(en)
|
2015-12-04 |
2018-06-28 |
Global Blood Therapeutics Inc |
Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
|
|
WO2017127930A1
(en)
|
2016-01-28 |
2017-08-03 |
Neomed Institute |
Substituted [1,2,4]triazolo[4,3-a]pyridines, their preparation and their use as pharmaceuticals
|
|
TWI663160B
(zh)
|
2016-05-12 |
2019-06-21 |
全球血液治療公司 |
用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
|
|
WO2018013430A2
(en)
|
2016-07-12 |
2018-01-18 |
Arisan Therapeutics Inc. |
Heterocyclic compounds for the treatment of arenavirus infection
|
|
JP2019533643A
(ja)
*
|
2016-09-14 |
2019-11-21 |
ヴァンダービルト ユニバーシティーVanderbilt University |
Bmpシグナル伝達の阻害、その化合物、組成物および使用
|
|
TW202332423A
(zh)
|
2016-10-12 |
2023-08-16 |
美商全球血液治療公司 |
包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
EP3746071A4
(en)
|
2018-01-29 |
2021-09-01 |
Merck Patent GmbH |
GCN2 INHIBITORS AND THEIR USES
|
|
WO2019178383A1
(en)
|
2018-03-14 |
2019-09-19 |
Vanderbilt University |
Inhibition of bmp signaling, compounds, compositions and uses thereof
|
|
CR20200590A
(es)
|
2018-05-04 |
2021-04-26 |
Incyte Corp |
Formas sólidas de un inhibidor de fgfr y procesos para prepararlas
|
|
MA52493A
(fr)
|
2018-05-04 |
2021-03-10 |
Incyte Corp |
Sels d'un inhibiteur de fgfr
|
|
US11014884B2
(en)
|
2018-10-01 |
2021-05-25 |
Global Blood Therapeutics, Inc. |
Modulators of hemoglobin
|
|
US12419865B2
(en)
|
2018-12-06 |
2025-09-23 |
Arisan Therapeutics Inc. |
Compounds for the treatment of arenavirus infection
|
|
CA3124088A1
(en)
|
2018-12-20 |
2020-06-25 |
Incyte Corporation |
Imidazopyridazine and imidazopyridine compounds as inhibitors of activin receptor-like kinase-2
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
KR102753831B1
(ko)
*
|
2019-07-26 |
2025-01-14 |
씨젠테크 (쑤저우, 차이나) 컴퍼니 리미티드 |
Fgfr 및 vegfr 이중 억제제로서의 피리딘 유도체
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
US12478624B2
(en)
|
2019-10-02 |
2025-11-25 |
Tolremo Therapeutics Ag |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer
|
|
WO2021076728A1
(en)
|
2019-10-16 |
2021-04-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
EP4069696A1
(en)
|
2019-12-04 |
2022-10-12 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
BR112022010664A2
(pt)
|
2019-12-04 |
2022-08-16 |
Incyte Corp |
Derivados de um inibidor de fgfr
|
|
CN111116582B
(zh)
*
|
2019-12-18 |
2022-07-29 |
大连大学 |
一种mGluR2拮抗剂
|
|
CN114980891A
(zh)
*
|
2019-12-19 |
2022-08-30 |
斯特拉斯堡大学 |
σ-1受体配体及其治疗用途
|
|
AU2021205893A1
(en)
|
2020-01-08 |
2022-06-23 |
Synthis Therapeutics, Inc. |
ALK5 inhibitor conjugates and uses thereof
|
|
WO2021146424A1
(en)
*
|
2020-01-15 |
2021-07-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2021147699A1
(zh)
*
|
2020-01-21 |
2021-07-29 |
四川科伦博泰生物医药股份有限公司 |
吡啶并杂环类化合物、其制备方法及用途
|
|
CN115956081A
(zh)
|
2020-06-12 |
2023-04-11 |
因赛特公司 |
具有作为alk2抑制剂的活性的咪唑并哒嗪化合物
|
|
CA3184062A1
(en)
*
|
2020-06-25 |
2021-12-30 |
Stefanie Fluckiger-Mangual |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of fibrotic disease
|
|
IL299344A
(en)
|
2020-06-25 |
2023-02-01 |
Tolremo Therapeutics Ag |
Combination of a cbp/p300 bromodomain inhibitor and a kras inhibitor for the treatment of cancer
|
|
ES2982017T3
(es)
|
2020-07-15 |
2024-10-14 |
Chiesi Farm Spa |
Derivados de pirido-oxazina como inhibidores de ALK5
|
|
KR20230041003A
(ko)
|
2020-07-15 |
2023-03-23 |
키에시 파르마슈티시 엣스. 피. 에이. |
Alk5 억제제로서 피리도 옥사진 아미노 유도체
|
|
PT4182308T
(pt)
|
2020-07-15 |
2024-12-04 |
Chiesi Farm Spa |
Derivados de piridazinil amino como inibidores de alk5
|
|
US20240116948A1
(en)
|
2020-12-23 |
2024-04-11 |
Chiesi Farmaceutici S.P.A. |
Pyrido oxazine derivatives as alk5 inhibitors
|
|
CA3206502A1
(en)
*
|
2021-01-26 |
2022-08-04 |
Zhengxia CHEN |
Crystal form of methylpyrazole-substituted pyridoimidazole compound and preparation method therefor
|
|
BR112023020538A2
(pt)
|
2021-04-07 |
2024-01-23 |
Tolremo Therapeutics Ag |
Derivados heterocíclicos, composições farmacêuticas e seus usos no tratamento ou na melhoria de câncer
|
|
TW202304459A
(zh)
|
2021-04-12 |
2023-02-01 |
美商英塞特公司 |
包含fgfr抑制劑及nectin-4靶向劑之組合療法
|
|
EP4352059A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
WO2022261159A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
AU2022351219A1
(en)
|
2021-09-21 |
2024-05-02 |
Chiesi Farmaceutici S.P.A. |
Pyridazinyl amino derivatives as alk5 inhibitors
|
|
AU2022359801A1
(en)
|
2021-10-04 |
2024-02-01 |
Forx Therapeutics Ag |
Parg inhibitory compounds
|
|
US20250270215A1
(en)
|
2022-04-27 |
2025-08-28 |
Chiesi Farmaceutici S.P.A. |
Imidazole derivatives as alk5 inhibitors
|
|
JP2025535036A
(ja)
|
2022-10-03 |
2025-10-22 |
フォークス セラピューティクス アーゲー |
Parg阻害化合物
|
|
WO2024209035A1
(en)
|
2023-04-05 |
2024-10-10 |
Forx Therapeutics Ag |
Parg inhibitory compounds
|
|
CN121712526A
(zh)
|
2023-06-13 |
2026-03-20 |
辛瑟斯治疗股份有限公司 |
抗cd5抗体及其用途
|
|
CN121889393A
(zh)
|
2023-10-03 |
2026-04-17 |
福克斯治疗股份公司 |
Parg抑制化合物
|