JP2011500024A - Rpe細胞を生成する改良された方法およびrpe細胞の組成物 - Google Patents
Rpe細胞を生成する改良された方法およびrpe細胞の組成物 Download PDFInfo
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- JP2011500024A JP2011500024A JP2010528899A JP2010528899A JP2011500024A JP 2011500024 A JP2011500024 A JP 2011500024A JP 2010528899 A JP2010528899 A JP 2010528899A JP 2010528899 A JP2010528899 A JP 2010528899A JP 2011500024 A JP2011500024 A JP 2011500024A
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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- A61P25/16—Anti-Parkinson drugs
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- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/73—Hydrolases (EC 3.)
- C12N2501/734—Proteases (EC 3.4.)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
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- Animal Behavior & Ethology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Biotechnology (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99876607P | 2007-10-12 | 2007-10-12 | |
| US99866807P | 2007-10-12 | 2007-10-12 | |
| US990808P | 2008-01-02 | 2008-01-02 | |
| US991108P | 2008-01-02 | 2008-01-02 | |
| PCT/US2008/011669 WO2009051671A1 (en) | 2007-10-12 | 2008-10-10 | Improved methods of producing rpe cells and compositions of rpe cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014125977A Division JP6137626B2 (ja) | 2007-10-12 | 2014-06-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011500024A true JP2011500024A (ja) | 2011-01-06 |
| JP2011500024A5 JP2011500024A5 (https=) | 2012-11-15 |
Family
ID=40567677
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528899A Withdrawn JP2011500024A (ja) | 2007-10-12 | 2008-10-10 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2014125977A Active JP6137626B2 (ja) | 2007-10-12 | 2014-06-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2017083243A Active JP6692768B2 (ja) | 2007-10-12 | 2017-04-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2020072683A Pending JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2022035111A Pending JP2022079484A (ja) | 2007-10-12 | 2022-03-08 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2024205622A Pending JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014125977A Active JP6137626B2 (ja) | 2007-10-12 | 2014-06-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2017083243A Active JP6692768B2 (ja) | 2007-10-12 | 2017-04-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2020072683A Pending JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2022035111A Pending JP2022079484A (ja) | 2007-10-12 | 2022-03-08 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2024205622A Pending JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20110274662A1 (https=) |
| EP (2) | EP3636748A1 (https=) |
| JP (6) | JP2011500024A (https=) |
| KR (2) | KR101849336B1 (https=) |
| CN (2) | CN101878295A (https=) |
| AU (1) | AU2008312007A1 (https=) |
| CA (3) | CA3006687C (https=) |
| DK (1) | DK2209888T3 (https=) |
| ES (1) | ES2764473T3 (https=) |
| IL (4) | IL292561A (https=) |
| PL (1) | PL2209888T3 (https=) |
| PT (1) | PT2209888T (https=) |
| WO (1) | WO2009051671A1 (https=) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013128477A (ja) * | 2011-11-25 | 2013-07-04 | Sumitomo Chemical Co Ltd | 網膜層特異的神経細胞を製造する方法 |
| JP2013128476A (ja) * | 2011-11-25 | 2013-07-04 | Sumitomo Chemical Co Ltd | 眼杯様構造体の製造方法 |
| JP2013128475A (ja) * | 2011-11-25 | 2013-07-04 | Sumitomo Chemical Co Ltd | 網膜組織の製造方法 |
| JP2013128474A (ja) * | 2011-11-25 | 2013-07-04 | Sumitomo Chemical Co Ltd | 網膜色素上皮細胞の製造方法 |
| WO2018003908A1 (ja) * | 2016-06-30 | 2018-01-04 | 株式会社ヘリオス | 移植用媒体 |
| JP2018500906A (ja) * | 2014-12-18 | 2018-01-18 | ユニヴェルシテ・ピエール・エ・マリ・キュリ・(パリ・6) | 網膜変性処置のためのotx2過剰発現トランスジェニック網膜色素上皮細胞 |
| JP2018523682A (ja) * | 2015-08-18 | 2018-08-23 | アステラス インスティテュート フォー リジェネレイティブ メディシン | 臨床製剤 |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| EP2929782A1 (en) | 2004-01-23 | 2015-10-14 | Ocata Therapeutics, Inc. | Improved modalities for the treatment of degenerative diseases of the retina |
| EP2128244A4 (en) | 2007-01-18 | 2012-05-09 | Riken | PROCESS FOR INDUCTION / DIFFERENTIATION TO A PHOTOREZEPTORZELLE |
| DK2209888T3 (da) | 2007-10-12 | 2020-01-20 | Astellas Inst For Regenerative Medicine | Forbedrede fremgangsmåder til fremstilling af rpe-celler og sammensætninger af rpe-celler |
| US8481313B2 (en) * | 2008-04-22 | 2013-07-09 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| JPWO2009148170A1 (ja) | 2008-06-06 | 2011-11-04 | 独立行政法人理化学研究所 | 幹細胞の培養方法 |
| US20120322670A1 (en) * | 2009-08-28 | 2012-12-20 | Cellular Dynamics International, Inc. | Identifying genetic variation in affected tissues |
| JP5787370B2 (ja) | 2009-11-05 | 2015-09-30 | 国立研究開発法人理化学研究所 | 幹細胞の分化誘導方法 |
| IL281453B (en) | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| ES2758554T3 (es) | 2009-12-08 | 2020-05-05 | Univ Case Western Reserve | Aminoácidos gama para tratamiento de trastornos oculares |
| WO2012012803A2 (en) * | 2010-07-23 | 2012-01-26 | Advanced Cell Technology, Inc. | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
| FI20106354A0 (fi) * | 2010-12-20 | 2010-12-20 | Suomen Punainen Risti Veripalvelu | Menetelmä ihmisen retinan pigmentti-epiteelisolujen valmistamiseksi |
| CA2835215C (en) | 2011-05-18 | 2023-10-10 | The Regents Of The University Of California | Non-immortal human retinal cell compositions, method for preparing them, and their use for treating retinal diseases |
| IL287381B2 (en) * | 2011-11-14 | 2024-04-01 | Astellas Inst For Regenerative Medicine | Pharmaceutical preparations of human rpe cells and uses thereof |
| EP2784152B1 (en) * | 2011-11-25 | 2019-04-10 | Sumitomo Chemical Company, Limited | Methods for producing retinal tissue and retina-related cell |
| JP6012164B2 (ja) * | 2011-11-25 | 2016-10-25 | 住友化学株式会社 | 多能性幹細胞由来の組織の凍結保存方法 |
| SI2785359T1 (sl) | 2011-11-30 | 2018-11-30 | Astellas Institute For Regenerative Medicine | Mezenhimske stromalne celice in uporabe povezane z njimi |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| HK1208054A1 (en) | 2012-07-12 | 2016-02-19 | 爱姆斯坦生物技术公司 | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| CA2896053A1 (en) | 2012-12-21 | 2014-06-26 | Ocata Therapeutics, Inc. | Methods for production of platelets from pluripotent stem cells and compositions thereof |
| EP2951290B1 (en) | 2013-02-01 | 2017-11-29 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs) |
| US20160060595A1 (en) * | 2013-04-03 | 2016-03-03 | Tampereen Yliopisto | Methods and media for differentiating eye cells |
| KR102278978B1 (ko) | 2013-08-23 | 2021-07-19 | 스미또모 가가꾸 가부시끼가이샤 | 망막 조직 및 망막 관련 세포의 제조 방법 |
| MX2016007671A (es) | 2013-12-11 | 2016-10-14 | Pfizer Ltd | Metodo para producir celulas del epitelio pigmentario retiniano. |
| TWI810142B (zh) | 2014-10-24 | 2023-08-01 | 日商住友製藥股份有限公司 | 神經組織的製造方法 |
| EP3211071B1 (en) | 2014-10-24 | 2021-05-05 | Sumitomo Dainippon Pharma Co., Ltd. | Production method for retinal tissue |
| CA2972575A1 (en) | 2014-12-30 | 2016-07-07 | Cell Cure Neurosciences Ltd. | Rpe cell populations and methods of generating same |
| EP3240612B1 (en) * | 2014-12-30 | 2020-12-23 | Cell Cure Neurosciences Ltd. | Methods of treating retinal diseases |
| SG10201907918VA (en) | 2015-03-23 | 2019-10-30 | Astellas Inst For Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors |
| US12385008B2 (en) | 2015-09-08 | 2025-08-12 | Sumitomo Pharma Co., Ltd. | Method for producing retinal tissue |
| DK3347456T3 (da) | 2015-09-08 | 2024-02-19 | Us Health | Fremgangsmåde til reproducerbar differentiering af retinale pigmentepitelceller af klinisk kvalitet |
| AU2016318774B2 (en) * | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| US10947502B2 (en) | 2015-10-20 | 2021-03-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for directed differentiation of pluripotent stem cells to immune cells |
| JP6987769B2 (ja) | 2015-10-26 | 2022-01-05 | セル キュア ニューロサイエンシズ リミテッド | 網膜色素上皮細胞の調製法 |
| SG11201809201UA (en) | 2016-04-22 | 2018-11-29 | Sumitomo Dainippon Pharma Co Ltd | Method for producing retinal tissue |
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