JP2011250786A5 - - Google Patents
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- JP2011250786A5 JP2011250786A5 JP2011127749A JP2011127749A JP2011250786A5 JP 2011250786 A5 JP2011250786 A5 JP 2011250786A5 JP 2011127749 A JP2011127749 A JP 2011127749A JP 2011127749 A JP2011127749 A JP 2011127749A JP 2011250786 A5 JP2011250786 A5 JP 2011250786A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- protein
- virus
- sample
- mpv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 241000351643 Metapneumovirus Species 0.000 claims 42
- 241000700605 Viruses Species 0.000 claims 22
- 108090000623 proteins and genes Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 20
- 108020004707 nucleic acids Proteins 0.000 claims 18
- 102000039446 nucleic acids Human genes 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 18
- 102000004169 proteins and genes Human genes 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 15
- 241000711955 Turkey rhinotracheitis virus Species 0.000 claims 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 208000015181 infectious disease Diseases 0.000 claims 8
- 230000002238 attenuated effect Effects 0.000 claims 6
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 claims 6
- 101001065501 Escherichia phage MS2 Lysis protein Proteins 0.000 claims 5
- 101710141454 Nucleoprotein Proteins 0.000 claims 5
- 229940039227 diagnostic agent Drugs 0.000 claims 4
- 239000000032 diagnostic agent Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 101150046652 M2 gene Proteins 0.000 claims 3
- 241000711904 Pneumoviridae Species 0.000 claims 3
- 238000009396 hybridization Methods 0.000 claims 3
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 claims 2
- 101150034814 F gene Proteins 0.000 claims 2
- 101150082239 G gene Proteins 0.000 claims 2
- 101150062031 L gene Proteins 0.000 claims 2
- 101150039699 M2-1 gene Proteins 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 108091092724 Noncoding DNA Proteins 0.000 claims 2
- 108700026244 Open Reading Frames Proteins 0.000 claims 2
- 101150084044 P gene Proteins 0.000 claims 2
- 241000711504 Paramyxoviridae Species 0.000 claims 2
- 101150107578 SH gene Proteins 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 241001493065 dsRNA viruses Species 0.000 claims 2
- 238000012239 gene modification Methods 0.000 claims 2
- 230000005017 genetic modification Effects 0.000 claims 2
- 235000013617 genetically modified food Nutrition 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 108020004705 Codon Proteins 0.000 claims 1
- 108091006027 G proteins Proteins 0.000 claims 1
- 102000030782 GTP binding Human genes 0.000 claims 1
- 108091000058 GTP-Binding Proteins 0.000 claims 1
- 101710085938 Matrix protein Proteins 0.000 claims 1
- 101710127721 Membrane protein Proteins 0.000 claims 1
- 102100034574 P protein Human genes 0.000 claims 1
- 101710181008 P protein Proteins 0.000 claims 1
- 101710177166 Phosphoprotein Proteins 0.000 claims 1
- 101001039853 Sonchus yellow net virus Matrix protein Proteins 0.000 claims 1
- 238000007792 addition Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000006798 recombination Effects 0.000 claims 1
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46581103P | 2003-04-25 | 2003-04-25 | |
| US60/465,811 | 2003-04-25 | ||
| US46677603P | 2003-04-30 | 2003-04-30 | |
| US60/466,776 | 2003-04-30 | ||
| US48065803P | 2003-06-20 | 2003-06-20 | |
| US60/480,658 | 2003-06-20 | ||
| US49864003P | 2003-08-28 | 2003-08-28 | |
| US60/498,640 | 2003-08-28 | ||
| US55091104P | 2004-03-05 | 2004-03-05 | |
| US60/550,911 | 2004-03-05 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513301A Division JP2007525178A (ja) | 2003-04-25 | 2004-04-23 | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011250786A JP2011250786A (ja) | 2011-12-15 |
| JP2011250786A5 true JP2011250786A5 (enExample) | 2012-09-13 |
Family
ID=33425744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513301A Pending JP2007525178A (ja) | 2003-04-25 | 2004-04-23 | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
| JP2011127749A Pending JP2011250786A (ja) | 2003-04-25 | 2011-06-07 | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513301A Pending JP2007525178A (ja) | 2003-04-25 | 2004-04-23 | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7704720B2 (enExample) |
| EP (3) | EP2494986A1 (enExample) |
| JP (2) | JP2007525178A (enExample) |
| CN (1) | CN101410519B (enExample) |
| AU (1) | AU2004235347B2 (enExample) |
| CA (1) | CA2523319A1 (enExample) |
| WO (1) | WO2004096993A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1351981T3 (da) * | 2001-01-19 | 2012-11-26 | Vironovative Bv | Et virus, der forårsager luftvejssygdom hos modtagelige pattedyr |
| US8715922B2 (en) * | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| US20030232061A1 (en) * | 2001-10-18 | 2003-12-18 | Fouchier Ronaldus Adrianus Maria | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| JP4553589B2 (ja) | 2002-02-21 | 2010-09-29 | メディミューン,エルエルシー | 組換えパラインフルエンザウイルス発現系とメタニューモウイルスから得られる異種抗原を含むワクチン |
| CA2494485A1 (en) * | 2002-07-25 | 2004-02-05 | Medimmune, Inc. | Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies |
| JP2006524511A (ja) * | 2003-04-25 | 2006-11-02 | メッドイミューン バクシーンズ,インコーポレイティド | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
| ATE488248T1 (de) | 2004-09-09 | 2010-12-15 | Novartis Vaccines & Diagnostic | Verminderung von potentiellen iatrogenen risiken in verbindung mit influenza impfstoffen |
| AU2006223138B2 (en) * | 2005-03-10 | 2012-04-05 | Medimmune, Llc | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus |
| JP4976376B2 (ja) * | 2005-04-08 | 2012-07-18 | メディミューン,エルエルシー | 哺乳動物メタニューモウイルスに対する抗体 |
| US20090123529A1 (en) * | 2005-10-03 | 2009-05-14 | Xiaomao Li | Nucleic acid immunological composition for human metapneumovirus |
| AU2008248905B2 (en) * | 2007-05-04 | 2014-05-29 | Nanotherapeutics, Inc. | Two-step temperature profile for the propagation of viruses |
| EP2069485A4 (en) * | 2007-07-13 | 2011-05-25 | Medimmune Llc | PREPARATION OF NEGATIVE STRAND RNA VIRUSES BY ELECTROPORATION |
| US20090186050A1 (en) * | 2007-11-16 | 2009-07-23 | Fouchier Ron A M | Live attenuated metapneumovirus strains and their use in vaccine formulations and chimeric metapneumovirus strains |
| BRPI0919250A2 (pt) | 2008-09-24 | 2015-12-15 | Medimmune Llc | métodos para a purificação de vírus |
| JP2014508144A (ja) * | 2011-01-26 | 2014-04-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイト | 免疫応答を刺激するためのプラットフォーム技術を利用するコンジュゲート |
| CN104995315A (zh) * | 2012-12-18 | 2015-10-21 | 梅里亚股份有限公司 | Ibv、csfv和ndv的高分辨熔解基因分型 |
| WO2014160463A1 (en) | 2013-03-13 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Prefusion rsv f proteins and their use |
| US10093702B2 (en) | 2013-03-15 | 2018-10-09 | Research Institute At Nationwide Children's Hospital | Metapneumovirus immunogens and related materials and methods |
| WO2014208821A1 (ko) * | 2013-06-27 | 2014-12-31 | 건국대학교기술지주 주식회사 | 신규한 조류메타뉴모바이러스 및 그 백신 |
| KR101560337B1 (ko) | 2013-06-27 | 2015-10-19 | 주식회사 카브 | 신규한 조류메타뉴모바이러스 및 그 백신 |
| CN104849463B (zh) * | 2014-11-18 | 2017-02-22 | 天津瑞普生物技术股份有限公司 | 一种鸡传染性支气管炎二价疫苗效力检验方法 |
| CL2014003373A1 (es) * | 2014-12-11 | 2015-04-10 | Univ Pontificia Catolica Chile | Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv. |
| US11324816B2 (en) | 2015-08-31 | 2022-05-10 | Technovax, Inc. | Human respiratory syncytial virus (HRSV) virus-like particles (VLPS) based vaccine |
| EP4349405A3 (en) | 2015-10-22 | 2024-06-19 | ModernaTX, Inc. | Respiratory virus vaccines |
| US11174292B2 (en) | 2016-03-29 | 2021-11-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Substitutions-modified prefusion RSV F proteins and their use |
| MA50335A (fr) | 2016-12-08 | 2020-08-19 | Modernatx Inc | Vaccins à acide nucléique contre des virus respiratoires |
| EP3554538A2 (en) | 2016-12-16 | 2019-10-23 | Institute for Research in Biomedicine | Novel recombinant prefusion rsv f proteins and uses thereof |
| EP3861010A1 (en) | 2018-10-02 | 2021-08-11 | Voyager Therapeutics, Inc. | Redirection of tropism of aav capsids |
| CN109628413A (zh) * | 2018-12-29 | 2019-04-16 | 广东和信健康科技有限公司 | 一种人偏肺病毒的培养方法及其产物和应用 |
| US11351242B1 (en) | 2019-02-12 | 2022-06-07 | Modernatx, Inc. | HMPV/hPIV3 mRNA vaccine composition |
| SG11202110646PA (en) * | 2019-05-20 | 2021-10-28 | Valneva Se | A subunit vaccine for treatment or prevention of a respiratory tract infection |
| CN113462656B (zh) * | 2021-03-24 | 2022-09-30 | 兰州生物制品研究所有限责任公司 | 一种人三型副流感病毒冷适应温度敏感株及其应用 |
| MX2024004936A (es) | 2021-11-02 | 2024-05-08 | Voyager Therapeutics Inc | Variantes de capsides de aav y sus usos. |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| WO1989010405A1 (en) | 1988-04-22 | 1989-11-02 | The Upjohn Company | Chimeric glycoproteins containig immunogenic segments of human parainfluenza virus type 3 |
| US5137819A (en) | 1988-07-08 | 1992-08-11 | University Of British Columbia | Cellulose binding fusion proteins for immobilization and purification of polypeptides |
| US5166057A (en) | 1989-08-28 | 1992-11-24 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand rna virus expression-systems |
| US5854037A (en) | 1989-08-28 | 1998-12-29 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand RNA virus expression systems and vaccines |
| US5824307A (en) * | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
| GB9200117D0 (en) | 1992-01-06 | 1992-02-26 | Connaught Lab | Production of recombinant chimeric proteins for vaccine use |
| US5496934A (en) | 1993-04-14 | 1996-03-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nucleic acids encoding a cellulose binding domain |
| PT702085E (pt) | 1994-07-18 | 2004-04-30 | Karl Klaus Conzelmann | Virus de arn de cadeia negativa nao segmentada infeccioso recombinante |
| US7153510B1 (en) | 1995-05-04 | 2006-12-26 | Yale University | Recombinant vesiculoviruses and their uses |
| DE69510207T3 (de) | 1995-08-09 | 2007-02-15 | Schweiz. Serum- & Impfinstitut Bern | Verfahren zur Herstellung von infektiösen minussträngigen RNA-Viren |
| CA2230033C (en) | 1995-09-27 | 2010-01-26 | Peter L. Collins | Production of infectious respiratory syncytial virus from cloned nucleotide sequences |
| US5869036A (en) * | 1995-12-08 | 1999-02-09 | St. Louis University | Live attenuated vaccines based on CP45 HPIV-3 strain and method to ensure attenuation in such vaccine |
| DE19547361A1 (de) | 1995-12-19 | 1997-06-26 | Degussa | Verfahren zur Herstellung von L-Aminosäuren durch Fermentation |
| EP0780478A1 (en) | 1995-12-21 | 1997-06-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for the indirect genotypic diagnosis of cadasil |
| ES2109189B1 (es) | 1996-03-14 | 1998-05-16 | Iberica Cyanamid | Vectores basados en genomas virales defectivos recombinantes y su empleo en la formulacion de vacunas. |
| US6180398B1 (en) * | 1996-07-12 | 2001-01-30 | Virogeneitics Corporation | Two-step immunization procedure against the pyramyxoviridae family of viruses using recombinant virus and subunit protein preparation |
| BR9710363A (pt) | 1996-07-15 | 2000-01-11 | Us Gov Health & Human Serv | "vìrus sincicial respirátorio recombinante infeccioso isolado, partìcula do mesmo, processos para estimular o sistema imunológico de um indivìduo para induzir proteção contra o vìrus sincicial respiratório e para produzir uma partìcula de vìrus sincicial respiratório recombinante, vacina para induzir proteção contra o vìrus sincicial respiratório recombinante composição e ceta de vìrus sincicial respiratório recombinante" |
| EP0932684A2 (en) | 1996-09-27 | 1999-08-04 | American Cyanamid Company | 3' genomic promoter region and polymerase gene mutations responsible for attenuation in viruses of the order designated mononegavirales |
| US7192593B2 (en) * | 1997-05-23 | 2007-03-20 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Use of recombinant parainfluenza viruses (PIVs) as vectors to protect against infection and disease caused by PIV and other human pathogens |
| KR100702523B1 (ko) | 1997-05-23 | 2007-04-04 | 더 가번먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 에즈 레프리젠티드 바이 더 디파트먼트 오브 헬쓰 앤드 휴먼 서비시즈 | 클로닝된 뉴클레오타이드 서열로부터 약독화된파라인플루엔자 바이러스를 제조하는 방법 |
| JP4434478B2 (ja) | 1997-07-11 | 2010-03-17 | イエール ユニバーシティー | リエンジニアリングされた外被を有するラブドウイルス |
| CA2302867A1 (en) | 1997-09-19 | 1999-04-01 | American Cyanamid Company | Attenuated respiratory syncytial viruses |
| US6146642A (en) * | 1998-09-14 | 2000-11-14 | Mount Sinai School Of Medicine, Of The City University Of New York | Recombinant new castle disease virus RNA expression systems and vaccines |
| AU6200399A (en) | 1998-10-05 | 2000-04-26 | Akzo Nobel N.V. | Avian pneumovirus vaccine and diagnostic agent |
| CN101392239A (zh) | 1999-07-09 | 2009-03-25 | 美国政府健康及人类服务部 | 减毒的人-牛嵌合副流感病毒(piv)疫苗 |
| FR2801607B1 (fr) | 1999-11-26 | 2001-12-28 | Merial Sas | Pneumovirus du canard et vaccins correspondants |
| CN102766605A (zh) | 1999-12-10 | 2012-11-07 | 由卫生与公众服务部代表的美利坚合众国政府 | 重组副流感病毒(piv)作为载体提供保护对抗piv及其他人类病原体引起的感染和疾病的用途 |
| JP2002025374A (ja) | 2000-07-07 | 2002-01-25 | Matsushita Electric Ind Co Ltd | Elシート及びこれを用いたスイッチ |
| CA2430115C (en) * | 2000-11-28 | 2013-02-26 | Aviron, Inc. | Recombinant rsv virus expression systems and vaccines |
| DK1351981T3 (da) * | 2001-01-19 | 2012-11-26 | Vironovative Bv | Et virus, der forårsager luftvejssygdom hos modtagelige pattedyr |
| US20030232061A1 (en) * | 2001-10-18 | 2003-12-18 | Fouchier Ronaldus Adrianus Maria | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| US8715922B2 (en) * | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| US7704509B2 (en) | 2001-11-21 | 2010-04-27 | United States Of America | Recovery of recombinant human parainfluenza virus type 1 (HPIV1) from cDNA and use of recombinant HPIV1 in immunogenic compositions and as vectors to elicit immune responses against PIV and other human pathogens |
| JP4553589B2 (ja) * | 2002-02-21 | 2010-09-29 | メディミューン,エルエルシー | 組換えパラインフルエンザウイルス発現系とメタニューモウイルスから得られる異種抗原を含むワクチン |
| DE10221836A1 (de) | 2002-05-16 | 2003-12-04 | Lohmann Animal Health Gmbh | Attenuierung von Metapneumovirus |
| AU2003294533A1 (en) | 2002-12-19 | 2004-07-14 | Universite Laval | Molecular methods and compositions for detecting and quantifying respiratory viruses |
| US7704491B2 (en) * | 2003-02-28 | 2010-04-27 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant human metapneumovirus and its use |
| JP2006524511A (ja) * | 2003-04-25 | 2006-11-02 | メッドイミューン バクシーンズ,インコーポレイティド | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
| US20040229219A1 (en) * | 2003-04-30 | 2004-11-18 | Gallaher William R. | Method of inhibiting human metapneumovirus and human coronavirus in the prevention and treatment of severe acute respiratory syndrome (SARS) |
| US9002545B2 (en) | 2011-01-07 | 2015-04-07 | Wabtec Holding Corp. | Data improvement system and method |
| US9820230B2 (en) | 2015-09-11 | 2017-11-14 | Texas Instruments Incorporated | Low power packet detection circuit for WLAN recievers |
-
2004
- 2004-04-23 US US10/831,780 patent/US7704720B2/en active Active
- 2004-04-23 EP EP11192988A patent/EP2494986A1/en not_active Withdrawn
- 2004-04-23 JP JP2006513301A patent/JP2007525178A/ja active Pending
- 2004-04-23 CN CN2004800178507A patent/CN101410519B/zh not_active Expired - Fee Related
- 2004-04-23 AU AU2004235347A patent/AU2004235347B2/en not_active Ceased
- 2004-04-23 WO PCT/US2004/012724 patent/WO2004096993A2/en not_active Ceased
- 2004-04-23 EP EP04750614A patent/EP1623006A4/en not_active Withdrawn
- 2004-04-23 EP EP11192999A patent/EP2494987A1/en not_active Withdrawn
- 2004-04-23 CA CA002523319A patent/CA2523319A1/en not_active Abandoned
-
2011
- 2011-06-07 JP JP2011127749A patent/JP2011250786A/ja active Pending
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