JP2011250786A5 - - Google Patents
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- JP2011250786A5 JP2011250786A5 JP2011127749A JP2011127749A JP2011250786A5 JP 2011250786 A5 JP2011250786 A5 JP 2011250786A5 JP 2011127749 A JP2011127749 A JP 2011127749A JP 2011127749 A JP2011127749 A JP 2011127749A JP 2011250786 A5 JP2011250786 A5 JP 2011250786A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- protein
- virus
- sample
- mpv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000351643 Metapneumovirus Species 0.000 claims 42
- 241000700605 Viruses Species 0.000 claims 22
- 108090000623 proteins and genes Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 20
- 108020004707 nucleic acids Proteins 0.000 claims 18
- 102000039446 nucleic acids Human genes 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 18
- 102000004169 proteins and genes Human genes 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 15
- 241000711955 Turkey rhinotracheitis virus Species 0.000 claims 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 208000015181 infectious disease Diseases 0.000 claims 8
- 230000002238 attenuated effect Effects 0.000 claims 6
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 claims 6
- 101001065501 Escherichia phage MS2 Lysis protein Proteins 0.000 claims 5
- 101710141454 Nucleoprotein Proteins 0.000 claims 5
- 229940039227 diagnostic agent Drugs 0.000 claims 4
- 239000000032 diagnostic agent Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 101150046652 M2 gene Proteins 0.000 claims 3
- 241000711904 Pneumoviridae Species 0.000 claims 3
- 238000009396 hybridization Methods 0.000 claims 3
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 claims 2
- 101150034814 F gene Proteins 0.000 claims 2
- 101150082239 G gene Proteins 0.000 claims 2
- 101150062031 L gene Proteins 0.000 claims 2
- 101150039699 M2-1 gene Proteins 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 108091092724 Noncoding DNA Proteins 0.000 claims 2
- 108700026244 Open Reading Frames Proteins 0.000 claims 2
- 101150084044 P gene Proteins 0.000 claims 2
- 241000711504 Paramyxoviridae Species 0.000 claims 2
- 101150107578 SH gene Proteins 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 241001493065 dsRNA viruses Species 0.000 claims 2
- 238000012239 gene modification Methods 0.000 claims 2
- 230000005017 genetic modification Effects 0.000 claims 2
- 235000013617 genetically modified food Nutrition 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 108020004705 Codon Proteins 0.000 claims 1
- 108091006027 G proteins Proteins 0.000 claims 1
- 102000030782 GTP binding Human genes 0.000 claims 1
- 108091000058 GTP-Binding Proteins 0.000 claims 1
- 101710085938 Matrix protein Proteins 0.000 claims 1
- 101710127721 Membrane protein Proteins 0.000 claims 1
- 102100034574 P protein Human genes 0.000 claims 1
- 101710181008 P protein Proteins 0.000 claims 1
- 101710177166 Phosphoprotein Proteins 0.000 claims 1
- 101001039853 Sonchus yellow net virus Matrix protein Proteins 0.000 claims 1
- 238000007792 addition Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000006798 recombination Effects 0.000 claims 1
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46581103P | 2003-04-25 | 2003-04-25 | |
| US60/465,811 | 2003-04-25 | ||
| US46677603P | 2003-04-30 | 2003-04-30 | |
| US60/466,776 | 2003-04-30 | ||
| US48065803P | 2003-06-20 | 2003-06-20 | |
| US60/480,658 | 2003-06-20 | ||
| US49864003P | 2003-08-28 | 2003-08-28 | |
| US60/498,640 | 2003-08-28 | ||
| US55091104P | 2004-03-05 | 2004-03-05 | |
| US60/550,911 | 2004-03-05 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513301A Division JP2007525178A (ja) | 2003-04-25 | 2004-04-23 | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011250786A JP2011250786A (ja) | 2011-12-15 |
| JP2011250786A5 true JP2011250786A5 (enExample) | 2012-09-13 |
Family
ID=33425744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513301A Pending JP2007525178A (ja) | 2003-04-25 | 2004-04-23 | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
| JP2011127749A Pending JP2011250786A (ja) | 2003-04-25 | 2011-06-07 | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513301A Pending JP2007525178A (ja) | 2003-04-25 | 2004-04-23 | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7704720B2 (enExample) |
| EP (3) | EP1623006A4 (enExample) |
| JP (2) | JP2007525178A (enExample) |
| CN (1) | CN101410519B (enExample) |
| AU (1) | AU2004235347B2 (enExample) |
| CA (1) | CA2523319A1 (enExample) |
| WO (1) | WO2004096993A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA93981C2 (ru) * | 2001-01-19 | 2011-03-25 | Вироновативе Б.B. | Вирус, который вызывает заболевание дыхательных путей у чувствительных k этому млекопитающих |
| US20030232061A1 (en) * | 2001-10-18 | 2003-12-18 | Fouchier Ronaldus Adrianus Maria | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| US8715922B2 (en) * | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| CA2477235A1 (en) | 2002-02-21 | 2003-09-04 | Medimmune Vaccines, Inc. | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| CA2494485A1 (en) * | 2002-07-25 | 2004-02-05 | Medimmune, Inc. | Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies |
| CA2523657A1 (en) * | 2003-04-25 | 2005-03-31 | Medimmune Vaccines, Inc. | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| EP2578229B1 (en) | 2004-09-09 | 2013-07-10 | Novartis Vaccines and Diagnostics GmbH | Decreasing potential iatrogenic risks associated with vaccine antigens |
| US20060216700A1 (en) * | 2005-03-10 | 2006-09-28 | Medimmune Vaccines, Inc. | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus |
| WO2006110214A2 (en) * | 2005-04-08 | 2006-10-19 | Medimmune, Inc. | Antibodies against mammalian metapneumovirus |
| WO2007038862A1 (en) * | 2005-10-03 | 2007-04-12 | Seneca College Of Applied Arts & Technology | Nucleic acid immunological composition for human metapneumovirus |
| ES2521496T3 (es) * | 2007-05-04 | 2014-11-12 | Baxter International Inc. | Perfil de temperatura en dos etapas para la propagación de virus |
| EP2069485A4 (en) * | 2007-07-13 | 2011-05-25 | Medimmune Llc | PREPARATION OF NEGATIVE STRAND RNA VIRUSES BY ELECTROPORATION |
| US20090186050A1 (en) * | 2007-11-16 | 2009-07-23 | Fouchier Ron A M | Live attenuated metapneumovirus strains and their use in vaccine formulations and chimeric metapneumovirus strains |
| JP5548207B2 (ja) | 2008-09-24 | 2014-07-16 | メディミューン，エルエルシー | ウイルスの精製方法 |
| US20140154282A1 (en) * | 2011-01-26 | 2014-06-05 | Robert S. Hodges | Conjugates utilizing platform technology for stimulating immune response |
| KR20150110531A (ko) * | 2012-12-18 | 2015-10-02 | 메리얼 인코포레이티드 | Ibv, csfv 및 ndv 의 고 해상도 용융 유전자형분석 |
| SMT202400297T1 (it) | 2013-03-13 | 2024-09-16 | The United States Of America As Represented By The Secretary Department Of Health And Human Services | Proteine f del rsv pre-fusione e loro uso |
| WO2014144153A2 (en) * | 2013-03-15 | 2014-09-18 | Ohio State Innovation Foundation | Metapneumovirus immunogens and related materials and methods |
| KR101560337B1 (ko) | 2013-06-27 | 2015-10-19 | 주식회사 카브 | 신규한 조류메타뉴모바이러스 및 그 백신 |
| WO2014208821A1 (ko) * | 2013-06-27 | 2014-12-31 | 건국대학교기술지주 주식회사 | 신규한 조류메타뉴모바이러스 및 그 백신 |
| CN104849463B (zh) * | 2014-11-18 | 2017-02-22 | 天津瑞普生物技术股份有限公司 | 一种鸡传染性支气管炎二价疫苗效力检验方法 |
| CL2014003373A1 (es) * | 2014-12-11 | 2015-04-10 | Univ Pontificia Catolica Chile | Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv. |
| EP3344290A4 (en) * | 2015-08-31 | 2019-02-27 | Technovax, Inc. | VACCINE BASED ON VIRUS-LIKE PARTICLES OF HUMAN RESPIRATORY SYNZYTIAL VIRUS (HRSV) |
| MA52645B1 (fr) | 2015-10-22 | 2022-06-30 | Modernatx Inc | Vaccins contre le virus respiratoire |
| CN109069611B (zh) | 2016-03-29 | 2022-11-04 | 美国政府(由卫生和人类服务部的部长所代表) | 取代修饰的融合前rsv f蛋白及其用途 |
| MA50335A (fr) | 2016-12-08 | 2020-08-19 | Modernatx Inc | Vaccins à acide nucléique contre des virus respiratoires |
| CA3043790A1 (en) | 2016-12-16 | 2018-06-21 | Institute For Research In Biomedicine | Novel recombinant prefusion rsv f proteins and uses thereof |
| AU2019354995B2 (en) * | 2018-10-02 | 2024-12-12 | Voyager Therapeutics, Inc. | Redirection of tropism of AAV capsids |
| CN109628413A (zh) * | 2018-12-29 | 2019-04-16 | 广东和信健康科技有限公司 | 一种人偏肺病毒的培养方法及其产物和应用 |
| US11351242B1 (en) | 2019-02-12 | 2022-06-07 | Modernatx, Inc. | HMPV/hPIV3 mRNA vaccine composition |
| EP3972639A1 (en) | 2019-05-20 | 2022-03-30 | Valneva SE | A subunit vaccine for treatment or prevention of a respiratory tract infection |
| CN113462656B (zh) * | 2021-03-24 | 2022-09-30 | 兰州生物制品研究所有限责任公司 | 一种人三型副流感病毒冷适应温度敏感株及其应用 |
| KR20240113624A (ko) | 2021-11-02 | 2024-07-22 | 보이저 테라퓨틱스, 인크. | Aav 캡시드 변이체 및 이의 용도 |
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| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| EP0413695B1 (en) | 1988-04-22 | 1994-05-04 | The Upjohn Company | Chimeric glycoproteins containing immunogenic segments of human parainfluenza virus type 3. |
| US5137819A (en) | 1988-07-08 | 1992-08-11 | University Of British Columbia | Cellulose binding fusion proteins for immobilization and purification of polypeptides |
| US5854037A (en) | 1989-08-28 | 1998-12-29 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand RNA virus expression systems and vaccines |
| US5166057A (en) | 1989-08-28 | 1992-11-24 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand rna virus expression-systems |
| US5824307A (en) | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
| GB9200117D0 (en) | 1992-01-06 | 1992-02-26 | Connaught Lab | Production of recombinant chimeric proteins for vaccine use |
| US5496934A (en) | 1993-04-14 | 1996-03-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nucleic acids encoding a cellulose binding domain |
| PT702085E (pt) | 1994-07-18 | 2004-04-30 | Karl Klaus Conzelmann | Virus de arn de cadeia negativa nao segmentada infeccioso recombinante |
| US7153510B1 (en) | 1995-05-04 | 2006-12-26 | Yale University | Recombinant vesiculoviruses and their uses |
| ATE181112T1 (de) | 1995-08-09 | 1999-06-15 | Schweiz Serum & Impfinst | Dem genom von minussträngigen rna-viren entsprechende cdna und verfahren zur herstellung von infektiösen minussträngigen rna-viren |
| CA2230033C (en) | 1995-09-27 | 2010-01-26 | Peter L. Collins | Production of infectious respiratory syncytial virus from cloned nucleotide sequences |
| US5869036A (en) | 1995-12-08 | 1999-02-09 | St. Louis University | Live attenuated vaccines based on CP45 HPIV-3 strain and method to ensure attenuation in such vaccine |
| DE19547361A1 (de) | 1995-12-19 | 1997-06-26 | Degussa | Verfahren zur Herstellung von L-Aminosäuren durch Fermentation |
| EP0780478A1 (en) | 1995-12-21 | 1997-06-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for the indirect genotypic diagnosis of cadasil |
| ES2109189B1 (es) | 1996-03-14 | 1998-05-16 | Iberica Cyanamid | Vectores basados en genomas virales defectivos recombinantes y su empleo en la formulacion de vacunas. |
| US6180398B1 (en) | 1996-07-12 | 2001-01-30 | Virogeneitics Corporation | Two-step immunization procedure against the pyramyxoviridae family of viruses using recombinant virus and subunit protein preparation |
| EP2112220A3 (en) | 1996-07-15 | 2010-01-06 | The Government of the United States of America, as represented by The Department of Health and Human Services | Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences |
| CA2265554A1 (en) | 1996-09-27 | 1998-04-02 | American Cyanamid Company | 3' genomic promoter region and polymerase gene mutations responsible for attenuation in viruses of the order designated mononegavirales |
| BR9809456B1 (pt) | 1997-05-23 | 2011-06-28 | molécula isolada de polinucleotìdeo, composição de célula ou isenta de célula, partìcula de piv infeciosa, atenuada e imunogênica, e, composição imunogênica. | |
| US7192593B2 (en) | 1997-05-23 | 2007-03-20 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Use of recombinant parainfluenza viruses (PIVs) as vectors to protect against infection and disease caused by PIV and other human pathogens |
| AU731663B2 (en) | 1997-07-11 | 2001-04-05 | Yale University | Rhabdoviruses with reengineered coats |
| CN1273603A (zh) | 1997-09-19 | 2000-11-15 | 美国氰胺公司 | 减毒的呼吸道合胞病毒 |
| US6146642A (en) | 1998-09-14 | 2000-11-14 | Mount Sinai School Of Medicine, Of The City University Of New York | Recombinant new castle disease virus RNA expression systems and vaccines |
| WO2000020600A1 (en) | 1998-10-05 | 2000-04-13 | Akzo Nobel N.V. | Avian pneumovirus vaccine and diagnostic agent |
| KR100940776B1 (ko) | 1999-07-09 | 2010-02-11 | 더 가버먼트 오브 더 유나이티드 스테이츠 오브 어메리카 애즈 리프리젠티드 바이 더 디파트먼트 오브 헬스 앤 휴먼 서비씨즈 | 약독화된 사람-소 키메라 파라인플루엔자바이러스(ｐｉｖ) 백신 |
| FR2801607B1 (fr) | 1999-11-26 | 2001-12-28 | Merial Sas | Pneumovirus du canard et vaccins correspondants |
| MXPA01008108A (es) | 1999-12-10 | 2004-11-12 | Health | Uso de virus de parainfluenza recombinante (pivs) como vectores para la proteccioncontra la infeccion y enfermedad provocadas por piv y otros patogenos humanos. |
| JP2002025374A (ja) | 2000-07-07 | 2002-01-25 | Matsushita Electric Ind Co Ltd | Ｅｌシート及びこれを用いたスイッチ |
| CA2797703A1 (en) * | 2000-11-28 | 2002-06-06 | Medimmune, Llc | Recombinant rsv virus expression systems and vaccines |
| US20030232061A1 (en) | 2001-10-18 | 2003-12-18 | Fouchier Ronaldus Adrianus Maria | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| UA93981C2 (ru) | 2001-01-19 | 2011-03-25 | Вироновативе Б.B. | Вирус, который вызывает заболевание дыхательных путей у чувствительных k этому млекопитающих |
| US8715922B2 (en) | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| EP1456398B1 (en) | 2001-11-21 | 2011-05-11 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Recovery of recombinant human parainfluenza virus type 1 (hpivi) from cdna |
| CA2477235A1 (en) | 2002-02-21 | 2003-09-04 | Medimmune Vaccines, Inc. | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| DE10221836A1 (de) | 2002-05-16 | 2003-12-04 | Lohmann Animal Health Gmbh | Attenuierung von Metapneumovirus |
| AU2003294533A1 (en) | 2002-12-19 | 2004-07-14 | Universite Laval | Molecular methods and compositions for detecting and quantifying respiratory viruses |
| JP2007524372A (ja) * | 2003-02-28 | 2007-08-30 | ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 組換えヒトメタニューモウイルスおよびその使用 |
| CA2523657A1 (en) | 2003-04-25 | 2005-03-31 | Medimmune Vaccines, Inc. | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| US20040229219A1 (en) | 2003-04-30 | 2004-11-18 | Gallaher William R. | Method of inhibiting human metapneumovirus and human coronavirus in the prevention and treatment of severe acute respiratory syndrome (SARS) |
| US9002545B2 (en) | 2011-01-07 | 2015-04-07 | Wabtec Holding Corp. | Data improvement system and method |
| US9820230B2 (en) | 2015-09-11 | 2017-11-14 | Texas Instruments Incorporated | Low power packet detection circuit for WLAN recievers |
-
2004
- 2004-04-23 JP JP2006513301A patent/JP2007525178A/ja active Pending
- 2004-04-23 US US10/831,780 patent/US7704720B2/en active Active
- 2004-04-23 EP EP04750614A patent/EP1623006A4/en not_active Withdrawn
- 2004-04-23 CN CN2004800178507A patent/CN101410519B/zh not_active Expired - Fee Related
- 2004-04-23 EP EP11192988A patent/EP2494986A1/en not_active Withdrawn
- 2004-04-23 CA CA002523319A patent/CA2523319A1/en not_active Abandoned
- 2004-04-23 AU AU2004235347A patent/AU2004235347B2/en not_active Ceased
- 2004-04-23 WO PCT/US2004/012724 patent/WO2004096993A2/en not_active Ceased
- 2004-04-23 EP EP11192999A patent/EP2494987A1/en not_active Withdrawn
-
2011
- 2011-06-07 JP JP2011127749A patent/JP2011250786A/ja active Pending
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