JP2011097946A5 - - Google Patents
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- JP2011097946A5 JP2011097946A5 JP2010280298A JP2010280298A JP2011097946A5 JP 2011097946 A5 JP2011097946 A5 JP 2011097946A5 JP 2010280298 A JP2010280298 A JP 2010280298A JP 2010280298 A JP2010280298 A JP 2010280298A JP 2011097946 A5 JP2011097946 A5 JP 2011097946A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- antigen
- antibody
- binding portion
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/706,689 US20050100965A1 (en) | 2003-11-12 | 2003-11-12 | IL-18 binding proteins |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539948A Division JP5054977B2 (ja) | 2003-11-12 | 2004-11-12 | Ｉｌ−１８結合タンパク質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011097946A JP2011097946A (ja) | 2011-05-19 |
| JP2011097946A5 true JP2011097946A5 (enExample) | 2012-03-01 |
Family
ID=34552597
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539948A Expired - Fee Related JP5054977B2 (ja) | 2003-11-12 | 2004-11-12 | Ｉｌ−１８結合タンパク質 |
| JP2010280298A Pending JP2011097946A (ja) | 2003-11-12 | 2010-12-16 | Ｉｌ−１８結合タンパク質 |
| JP2010280299A Pending JP2011097947A (ja) | 2003-11-12 | 2010-12-16 | Ｉｌ−１８結合タンパク質 |
| JP2012028435A Pending JP2012139223A (ja) | 2003-11-12 | 2012-02-13 | Ｉｌ−１８結合タンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539948A Expired - Fee Related JP5054977B2 (ja) | 2003-11-12 | 2004-11-12 | Ｉｌ−１８結合タンパク質 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010280299A Pending JP2011097947A (ja) | 2003-11-12 | 2010-12-16 | Ｉｌ−１８結合タンパク質 |
| JP2012028435A Pending JP2012139223A (ja) | 2003-11-12 | 2012-02-13 | Ｉｌ−１８結合タンパク質 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20050100965A1 (enExample) |
| EP (5) | EP2395020A3 (enExample) |
| JP (4) | JP5054977B2 (enExample) |
| KR (4) | KR20130006525A (enExample) |
| CN (4) | CN1902229B (enExample) |
| AT (1) | ATE555130T1 (enExample) |
| AU (1) | AU2004290073B2 (enExample) |
| BR (1) | BRPI0416255A (enExample) |
| CA (2) | CA2543920A1 (enExample) |
| CY (1) | CY1112893T1 (enExample) |
| DK (1) | DK1685152T3 (enExample) |
| ES (1) | ES2385484T3 (enExample) |
| IL (2) | IL175422A0 (enExample) |
| NZ (2) | NZ593068A (enExample) |
| PL (1) | PL1685152T3 (enExample) |
| PT (1) | PT1685152E (enExample) |
| SI (1) | SI1685152T1 (enExample) |
| WO (1) | WO2005047307A2 (enExample) |
| ZA (1) | ZA200603733B (enExample) |
Families Citing this family (76)
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| US20050100965A1 (en) * | 2003-11-12 | 2005-05-12 | Tariq Ghayur | IL-18 binding proteins |
| EP4793360A2 (en) | 2006-03-31 | 2026-08-19 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
| MX2008014842A (es) | 2006-05-25 | 2009-02-17 | Glaxo Group Ltd | Anticuerpos humanizados contra interleuquina-18 modificados. |
| EP2500416A1 (en) * | 2006-09-13 | 2012-09-19 | Abbott Laboratories | Cell culture improvements |
| TW201516149A (zh) | 2006-09-13 | 2015-05-01 | Abbvie Inc | 細胞培養改良 |
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| CA2987970A1 (en) * | 2006-11-21 | 2008-05-29 | Abbvie Inc. | Neutralizing monoclonal antibodies against the nogo-66 receptor (ngr) and uses thereof |
| EP3127921A1 (en) | 2007-09-26 | 2017-02-08 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substition in cdr |
| MX2010008364A (es) * | 2008-01-30 | 2010-08-23 | Abbott Lab | Composiciones y metodos para cristalizar fragmentos de anticuerpo. |
| TW201920257A (zh) | 2008-04-11 | 2019-06-01 | 日商中外製藥股份有限公司 | 重複結合複數個抗原的抗原結合分子 |
| JP2009284771A (ja) * | 2008-05-27 | 2009-12-10 | Takara Bio Inc | 抗体産生細胞の作製方法 |
| CN102834413A (zh) | 2010-02-09 | 2012-12-19 | 葛兰素集团有限公司 | 代谢障碍的治疗 |
| KR102049223B1 (ko) | 2010-11-04 | 2019-11-28 | 베링거 인겔하임 인터내셔날 게엠베하 | 항－ｉｌ－２３ 항체 |
| TWI654203B (zh) | 2010-11-30 | 2019-03-21 | Chugai Seiyaku Kabushiki Kaisha | 具有鈣依存性的抗原結合能力之抗體 |
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| WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| BR112014009866A2 (pt) | 2011-10-25 | 2018-09-04 | Onclave Therapeutics Limited | formulações de anticorpos e métodos |
| CA2865158C (en) | 2012-02-24 | 2022-11-01 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule for promoting disappearance of antigen via fc.gamma.riib |
| US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
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| CN109206516A (zh) | 2012-05-03 | 2019-01-15 | 勃林格殷格翰国际有限公司 | 抗IL-23p19抗体 |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| TWI855488B (zh) | 2012-08-24 | 2024-09-11 | 日商中外製藥股份有限公司 | FcγRIIb特異性Fc區域變異體 |
| JP6774164B2 (ja) | 2012-08-24 | 2020-10-21 | 中外製薬株式会社 | マウスＦｃγＲＩＩ特異的Ｆｃ抗体 |
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| US9376489B2 (en) * | 2012-09-07 | 2016-06-28 | Novartis Ag | IL-18 binding molecules |
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| WO2014080866A1 (ja) | 2012-11-21 | 2014-05-30 | 一般財団法人化学及血清療法研究所 | 新規なヒト抗ｉｌ－１８抗体 |
| WO2014126277A1 (ko) | 2013-02-14 | 2014-08-21 | 건국대학교 산학협력단 | 신규한 인터루킨-33 수용체와 결합 단백질 조성물 및 그 용도 |
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| US10335449B2 (en) * | 2014-10-06 | 2019-07-02 | University Of Houston System | Rho associated kinase (ROCK) inhibitors and their use in treating disease |
| MX2017005774A (es) | 2014-12-19 | 2017-07-28 | Chugai Pharmaceutical Co Ltd | Anticuerpos antimiostatina, polipeptidos que contienen regiones fc variantes, y metodos de uso. |
| KR20170120616A (ko) | 2015-02-04 | 2017-10-31 | 베링거 인겔하임 인터내셔날 게엠베하 | 염증성 질환의 치료 방법 |
| CN114773469B (zh) | 2015-02-05 | 2025-12-19 | 中外制药株式会社 | 包含离子浓度依赖性的抗原结合结构域的抗体，fc区变体，il-8-结合抗体及其应用 |
| CN104725514A (zh) * | 2015-02-06 | 2015-06-24 | 中国药科大学 | 新型il23拮抗剂 |
| CN107660150B (zh) | 2015-03-05 | 2023-10-24 | Ab2生物股份有限公司 | Il-18结合蛋白(il-18bp)和抗体在炎性疾病中 |
| KR101943989B1 (ko) | 2015-06-05 | 2019-01-30 | 삼성전자주식회사 | 데이터를 송수신하는 방법, 서버 및 단말기 |
| EP3394098A4 (en) | 2015-12-25 | 2019-11-13 | Chugai Seiyaku Kabushiki Kaisha | ANTI-MYOSTATIN ANTIBODIES AND METHOD OF USE |
| WO2017145166A1 (en) * | 2016-02-25 | 2017-08-31 | B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University | Composition and method for treating amyotrophic lateral sclerosis |
| CN116271014A (zh) | 2016-08-05 | 2023-06-23 | 中外制药株式会社 | 用于预防或治疗il-8相关疾病的组合物 |
| CN109641971B (zh) * | 2016-08-25 | 2023-04-04 | Jcr制药股份有限公司 | 抗体融合蛋白的制造方法 |
| SG10201607778XA (en) | 2016-09-16 | 2018-04-27 | Chugai Pharmaceutical Co Ltd | Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use |
| TWI827585B (zh) | 2018-03-15 | 2024-01-01 | 日商中外製藥股份有限公司 | 對茲卡病毒具有交叉反應性的抗登革病毒抗體及其使用方法 |
| CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
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| TW202210511A (zh) * | 2020-06-01 | 2022-03-16 | 美商阿法羅醫療股份有限公司 | 涉及il-18抗體之方法及治療 |
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| JP7880582B2 (ja) | 2021-07-13 | 2026-06-26 | 国立大学法人東海国立大学機構 | 炎症性腸疾患を治療するための医薬組成物 |
| US20240400716A1 (en) * | 2021-11-09 | 2024-12-05 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Molecules that bind to prostate specific membrane antigen (psma) polypeptides |
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| EP4453037A2 (en) * | 2021-12-23 | 2024-10-30 | Prothena Biosciences Limited | Antibodies recognizing sortilin |
| CN117177999B (zh) * | 2022-01-14 | 2024-07-05 | 和径医药科技（上海）有限公司 | 一种靶向IL-18Rβ的抗体及其应用 |
| CN118852426A (zh) * | 2023-04-26 | 2024-10-29 | 北京惟奥生物科技有限公司 | 结合il-18受体的抗体、il-18受体激活剂及其应用 |
| WO2024243819A1 (zh) * | 2023-05-30 | 2024-12-05 | 上海洛启生物医药技术有限公司 | 抗白介素18受体的纳米抗体及其应用 |
| CN117986360B (zh) * | 2024-02-01 | 2024-08-27 | 生物岛实验室 | Il18蛋白的特异性抗体及其制备方法与应用 |
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| US20020029391A1 (en) | 1998-04-15 | 2002-03-07 | Claude Geoffrey Davis | Epitope-driven human antibody production and gene expression profiling |
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-
2003
- 2003-11-12 US US10/706,689 patent/US20050100965A1/en not_active Abandoned
-
2004
- 2004-11-12 AT AT04817825T patent/ATE555130T1/de active
- 2004-11-12 BR BRPI0416255-2A patent/BRPI0416255A/pt not_active IP Right Cessation
- 2004-11-12 WO PCT/US2004/037971 patent/WO2005047307A2/en not_active Ceased
- 2004-11-12 KR KR1020127031335A patent/KR20130006525A/ko not_active Ceased
- 2004-11-12 CA CA002543920A patent/CA2543920A1/en not_active Abandoned
- 2004-11-12 CN CN2004800399482A patent/CN1902229B/zh not_active Expired - Fee Related
- 2004-11-12 PL PL04817825T patent/PL1685152T3/pl unknown
- 2004-11-12 EP EP11173650A patent/EP2395020A3/en not_active Withdrawn
- 2004-11-12 ES ES04817825T patent/ES2385484T3/es not_active Expired - Lifetime
- 2004-11-12 EP EP11173631A patent/EP2460830A3/en not_active Withdrawn
- 2004-11-12 CA CA2805859A patent/CA2805859A1/en not_active Abandoned
- 2004-11-12 CN CN201010274020XA patent/CN101979412A/zh active Pending
- 2004-11-12 NZ NZ593068A patent/NZ593068A/xx not_active IP Right Cessation
- 2004-11-12 KR KR1020067009221A patent/KR20060123148A/ko not_active Ceased
- 2004-11-12 EP EP11173595A patent/EP2385070A1/en not_active Withdrawn
- 2004-11-12 PT PT04817825T patent/PT1685152E/pt unknown
- 2004-11-12 DK DK04817825.5T patent/DK1685152T3/da active
- 2004-11-12 CN CN2012101293119A patent/CN102659944A/zh active Pending
- 2004-11-12 SI SI200431865T patent/SI1685152T1/sl unknown
- 2004-11-12 NZ NZ582097A patent/NZ582097A/en not_active IP Right Cessation
- 2004-11-12 EP EP11173615A patent/EP2460829A3/en not_active Withdrawn
- 2004-11-12 CN CN2010102739861A patent/CN101948539B/zh not_active Expired - Fee Related
- 2004-11-12 JP JP2006539948A patent/JP5054977B2/ja not_active Expired - Fee Related
- 2004-11-12 KR KR1020127028781A patent/KR20120136416A/ko not_active Ceased
- 2004-11-12 AU AU2004290073A patent/AU2004290073B2/en not_active Ceased
- 2004-11-12 EP EP04817825A patent/EP1685152B1/en not_active Expired - Lifetime
- 2004-11-12 KR KR1020127001647A patent/KR101282320B1/ko not_active Expired - Fee Related
-
2006
- 2006-05-04 IL IL175422A patent/IL175422A0/en unknown
- 2006-05-10 ZA ZA200603733A patent/ZA200603733B/en unknown
-
2010
- 2010-07-13 IL IL206979A patent/IL206979A0/en unknown
- 2010-12-16 JP JP2010280298A patent/JP2011097946A/ja active Pending
- 2010-12-16 JP JP2010280299A patent/JP2011097947A/ja active Pending
-
2012
- 2012-02-13 JP JP2012028435A patent/JP2012139223A/ja active Pending
- 2012-07-05 CY CY20121100602T patent/CY1112893T1/el unknown
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