JP2011097946A5 - - Google Patents
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- JP2011097946A5 JP2011097946A5 JP2010280298A JP2010280298A JP2011097946A5 JP 2011097946 A5 JP2011097946 A5 JP 2011097946A5 JP 2010280298 A JP2010280298 A JP 2010280298A JP 2010280298 A JP2010280298 A JP 2010280298A JP 2011097946 A5 JP2011097946 A5 JP 2011097946A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- antigen
- antibody
- binding portion
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/706,689 US20050100965A1 (en) | 2003-11-12 | 2003-11-12 | IL-18 binding proteins |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539948A Division JP5054977B2 (ja) | 2003-11-12 | 2004-11-12 | Ｉｌ−１８結合タンパク質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011097946A JP2011097946A (ja) | 2011-05-19 |
| JP2011097946A5 true JP2011097946A5 (enExample) | 2012-03-01 |
Family
ID=34552597
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539948A Expired - Fee Related JP5054977B2 (ja) | 2003-11-12 | 2004-11-12 | Ｉｌ−１８結合タンパク質 |
| JP2010280298A Pending JP2011097946A (ja) | 2003-11-12 | 2010-12-16 | Ｉｌ−１８結合タンパク質 |
| JP2010280299A Pending JP2011097947A (ja) | 2003-11-12 | 2010-12-16 | Ｉｌ−１８結合タンパク質 |
| JP2012028435A Pending JP2012139223A (ja) | 2003-11-12 | 2012-02-13 | Ｉｌ−１８結合タンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539948A Expired - Fee Related JP5054977B2 (ja) | 2003-11-12 | 2004-11-12 | Ｉｌ−１８結合タンパク質 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010280299A Pending JP2011097947A (ja) | 2003-11-12 | 2010-12-16 | Ｉｌ−１８結合タンパク質 |
| JP2012028435A Pending JP2012139223A (ja) | 2003-11-12 | 2012-02-13 | Ｉｌ−１８結合タンパク質 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20050100965A1 (enExample) |
| EP (5) | EP1685152B1 (enExample) |
| JP (4) | JP5054977B2 (enExample) |
| KR (4) | KR20060123148A (enExample) |
| CN (4) | CN102659944A (enExample) |
| AT (1) | ATE555130T1 (enExample) |
| AU (1) | AU2004290073B2 (enExample) |
| BR (1) | BRPI0416255A (enExample) |
| CA (2) | CA2543920A1 (enExample) |
| CY (1) | CY1112893T1 (enExample) |
| DK (1) | DK1685152T3 (enExample) |
| ES (1) | ES2385484T3 (enExample) |
| IL (2) | IL175422A0 (enExample) |
| NZ (2) | NZ582097A (enExample) |
| PL (1) | PL1685152T3 (enExample) |
| PT (1) | PT1685152E (enExample) |
| SI (1) | SI1685152T1 (enExample) |
| WO (1) | WO2005047307A2 (enExample) |
| ZA (1) | ZA200603733B (enExample) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050100965A1 (en) * | 2003-11-12 | 2005-05-12 | Tariq Ghayur | IL-18 binding proteins |
| CN104761637B (zh) | 2006-03-31 | 2021-10-15 | 中外制药株式会社 | 调控抗体血液动力学的方法 |
| AU2007267213B2 (en) | 2006-05-25 | 2012-03-29 | Glaxo Group Limited | Modified humanised anti-interleukin-18 antibodies |
| MX353340B (es) | 2006-09-13 | 2018-01-09 | Abbvie Inc | Mejoras de cultivos celulares. |
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| EP2500414A1 (en) * | 2006-09-13 | 2012-09-19 | Abbott Laboratories | Cell culture improvements |
| JP5653622B2 (ja) | 2006-11-21 | 2015-01-14 | アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ | Ｎｏｇｏ−６６受容体（ＮＧＲ）に対する中和モノクローナル抗体及びその使用 |
| CN101874042B9 (zh) | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| US20090202557A1 (en) * | 2008-01-30 | 2009-08-13 | Argiriadi Maria A | Compositions and methods for crystallizing antibody fragments |
| EP2275443B1 (en) | 2008-04-11 | 2015-12-02 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| JP2009284771A (ja) * | 2008-05-27 | 2009-12-10 | Takara Bio Inc | 抗体産生細胞の作製方法 |
| US20120308564A1 (en) | 2010-02-09 | 2012-12-06 | Andrew Ian Bayliffe | Treatment of a metabolic disorder |
| SG190006A1 (en) | 2010-11-04 | 2013-06-28 | Boehringer Ingelheim Int | Anti-il-23 antibodies |
| TWI654204B (zh) | 2010-11-30 | 2019-03-21 | Chugai Seiyaku Kabushiki Kaisha | 具有鈣依存性的抗原結合能力之抗體 |
| CA2822515C (en) | 2010-12-20 | 2023-04-25 | Medimmune Limited | Anti-il-18 antibodies and their uses |
| US9062106B2 (en) | 2011-04-27 | 2015-06-23 | Abbvie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| CA2853112C (en) | 2011-10-25 | 2018-08-21 | Onclave Therapeutics Limited | Antibody formulations and methods |
| WO2013125667A1 (ja) | 2012-02-24 | 2013-08-29 | 中外製薬株式会社 | FcγRIIBを介して抗原の消失を促進する抗原結合分子 |
| WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
| CN104507497B (zh) * | 2012-05-03 | 2018-10-19 | 勃林格殷格翰国际有限公司 | 抗IL-23p19抗体 |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| SG11201500873XA (en) | 2012-08-24 | 2015-04-29 | Chugai Pharmaceutical Co Ltd | Fcgriib-specific fc region variant |
| WO2014030750A1 (ja) | 2012-08-24 | 2014-02-27 | 中外製薬株式会社 | マウスFcγRII特異的Fc抗体 |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
| KR20150043523A (ko) | 2012-09-02 | 2015-04-22 | 애브비 인코포레이티드 | 단백질 불균일성의 제어 방법 |
| US9376489B2 (en) | 2012-09-07 | 2016-06-28 | Novartis Ag | IL-18 binding molecules |
| JP2016501203A (ja) | 2012-11-20 | 2016-01-18 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インドールアミン２，３−ジオキシゲナーゼの阻害剤として有用な化合物 |
| ES2742413T3 (es) * | 2012-11-21 | 2020-02-14 | Km Biologics Co Ltd | Nuevo anticuerpo humano contra IL-18 |
| WO2014126277A1 (ko) | 2013-02-14 | 2014-08-21 | 건국대학교 산학협력단 | 신규한 인터루킨-33 수용체와 결합 단백질 조성물 및 그 용도 |
| SG11201507230PA (en) | 2013-03-12 | 2015-10-29 | Abbvie Inc | Human antibodies that bind human tnf-alpha and methods of preparing the same |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| US8921526B2 (en) | 2013-03-14 | 2014-12-30 | Abbvie, Inc. | Mutated anti-TNFα antibodies and methods of their use |
| WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
| TWI636062B (zh) | 2013-04-02 | 2018-09-21 | 中外製藥股份有限公司 | Fc region variant |
| US9676853B2 (en) * | 2013-05-31 | 2017-06-13 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind PD-1 |
| PT3041864T (pt) * | 2013-09-05 | 2021-10-26 | Ab2 Bio Sa | Proteína de ligação a il-18 (il-18bp) em doenças inflamatórias |
| EP3052640A2 (en) | 2013-10-04 | 2016-08-10 | AbbVie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| SG10202113019XA (en) * | 2014-06-04 | 2021-12-30 | Amgen Inc | Methods for harvesting mammalian cell cultures |
| WO2016014775A1 (en) | 2014-07-24 | 2016-01-28 | Boehringer Ingelheim International Gmbh | Biomarkers useful in the treatment of il-23a related diseases |
| AR101753A1 (es) | 2014-09-03 | 2017-01-11 | Boehringer Ingelheim Int | COMPUESTO DE OBJETIVO A IL-23A Y TNF-a Y USO DEL MISMO |
| WO2016057306A1 (en) * | 2014-10-06 | 2016-04-14 | University Of Houston | Rho associated kinase (rock) inhibitors and their use in treating disease |
| NZ730607A (en) | 2014-12-19 | 2022-07-01 | Chugai Pharmaceutical Co Ltd | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
| SG10202103879YA (en) | 2015-02-04 | 2021-05-28 | Boehringer Ingelheim Int | Methods of treating inflammatory diseases |
| WO2016125495A1 (en) | 2015-02-05 | 2016-08-11 | Chugai Seiyaku Kabushiki Kaisha | Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof |
| CN104725514A (zh) * | 2015-02-06 | 2015-06-24 | 中国药科大学 | 新型il23拮抗剂 |
| UA128752C2 (uk) | 2015-03-05 | 2024-10-16 | Аб2 Біо Са | Фармацевтична композиція для лікування асоційованого з il-18 захворювання або порушення |
| KR101943989B1 (ko) | 2015-06-05 | 2019-01-30 | 삼성전자주식회사 | 데이터를 송수신하는 방법, 서버 및 단말기 |
| WO2017110981A1 (en) | 2015-12-25 | 2017-06-29 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| WO2017145166A1 (en) * | 2016-02-25 | 2017-08-31 | B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University | Composition and method for treating amyotrophic lateral sclerosis |
| BR112019001902A2 (pt) | 2016-08-05 | 2019-07-09 | Chugai Seiyaku Kabushiki Kaisha | composição para profilaxia ou tratamento de doenças relacionadas à il-8 |
| KR102318480B1 (ko) | 2016-08-25 | 2021-10-28 | 제이씨알 파마 가부시키가이샤 | 항체 융합 단백질의 제조 방법 |
| SG10201607778XA (en) | 2016-09-16 | 2018-04-27 | Chugai Pharmaceutical Co Ltd | Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use |
| CA3093729A1 (en) | 2018-03-15 | 2019-09-19 | Chugai Seiyaku Kabushiki Kaisha | Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use |
| CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
| DE102018220631A1 (de) | 2018-11-29 | 2020-06-04 | B. Braun Melsungen Ag | Wässrige Zusammensetzung, insbesondere zur Behandlung von Schleimhaut und/oder Wunden |
| US12269874B2 (en) | 2018-12-03 | 2025-04-08 | mAbProtein Co., Ltd. | Antibody that recognizes neoepitope of activated interleukin-18 proteins and application thereof |
| TW202123965A (zh) | 2019-09-09 | 2021-07-01 | 德商百靈佳殷格翰國際股份有限公司 | 抗-il-23p19抗體調配物 |
| KR20230051617A (ko) * | 2020-03-13 | 2023-04-18 | 얀센 바이오테크 인코포레이티드 | Siglec-3/cd33을 결합시키기 위한 물질 및 방법 |
| KR20230012539A (ko) | 2020-05-13 | 2023-01-26 | 디스크 메디슨, 인크. | 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체 |
| WO2021247454A1 (en) * | 2020-06-01 | 2021-12-09 | Avalo Therapeutics, Inc. | Methods and treatment involving antibodies to il-18 |
| AU2021297540A1 (en) | 2020-06-24 | 2023-02-02 | Prothena Biosciences Limited | Antibodies recognizing sortilin |
| EP4371573A4 (en) | 2021-07-13 | 2025-08-20 | National Univ Corporation Tokai National Higher Education And Research System | MEDICINAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE |
| WO2023086336A2 (en) * | 2021-11-09 | 2023-05-19 | University Of Pittsburgh – Of The Commonwealth System Of Higher Education | Molecules that bind to prostate specific membrane antigen (psma) polypeptides |
| AU2022394462A1 (en) | 2021-11-17 | 2024-05-02 | AbbVie Deutschland GmbH & Co. KG | Methods for treating anemia of kidney disease |
| EP4453037A2 (en) * | 2021-12-23 | 2024-10-30 | Prothena Biosciences Limited | Antibodies recognizing sortilin |
| WO2023134767A1 (zh) * | 2022-01-14 | 2023-07-20 | 和径医药科技（上海）有限公司 | 一种靶向IL-18Rβ的抗体及其应用 |
| CN118852426A (zh) * | 2023-04-26 | 2024-10-29 | 北京惟奥生物科技有限公司 | 结合il-18受体的抗体、il-18受体激活剂及其应用 |
| WO2024243819A1 (zh) * | 2023-05-30 | 2024-12-05 | 上海洛启生物医药技术有限公司 | 抗白介素18受体的纳米抗体及其应用 |
| CN117986360B (zh) * | 2024-02-01 | 2024-08-27 | 生物岛实验室 | Il18蛋白的特异性抗体及其制备方法与应用 |
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-
2003
- 2003-11-12 US US10/706,689 patent/US20050100965A1/en not_active Abandoned
-
2004
- 2004-11-12 JP JP2006539948A patent/JP5054977B2/ja not_active Expired - Fee Related
- 2004-11-12 AU AU2004290073A patent/AU2004290073B2/en not_active Ceased
- 2004-11-12 NZ NZ582097A patent/NZ582097A/en not_active IP Right Cessation
- 2004-11-12 DK DK04817825.5T patent/DK1685152T3/da active
- 2004-11-12 EP EP04817825A patent/EP1685152B1/en not_active Expired - Lifetime
- 2004-11-12 WO PCT/US2004/037971 patent/WO2005047307A2/en not_active Ceased
- 2004-11-12 AT AT04817825T patent/ATE555130T1/de active
- 2004-11-12 EP EP11173595A patent/EP2385070A1/en not_active Withdrawn
- 2004-11-12 NZ NZ593068A patent/NZ593068A/xx not_active IP Right Cessation
- 2004-11-12 CA CA002543920A patent/CA2543920A1/en not_active Abandoned
- 2004-11-12 KR KR1020067009221A patent/KR20060123148A/ko not_active Ceased
- 2004-11-12 EP EP11173615A patent/EP2460829A3/en not_active Withdrawn
- 2004-11-12 SI SI200431865T patent/SI1685152T1/sl unknown
- 2004-11-12 PT PT04817825T patent/PT1685152E/pt unknown
- 2004-11-12 CN CN2012101293119A patent/CN102659944A/zh active Pending
- 2004-11-12 EP EP11173631A patent/EP2460830A3/en not_active Withdrawn
- 2004-11-12 KR KR1020127028781A patent/KR20120136416A/ko not_active Ceased
- 2004-11-12 CN CN2004800399482A patent/CN1902229B/zh not_active Expired - Fee Related
- 2004-11-12 ES ES04817825T patent/ES2385484T3/es not_active Expired - Lifetime
- 2004-11-12 EP EP11173650A patent/EP2395020A3/en not_active Withdrawn
- 2004-11-12 KR KR1020127031335A patent/KR20130006525A/ko not_active Ceased
- 2004-11-12 CN CN2010102739861A patent/CN101948539B/zh not_active Expired - Fee Related
- 2004-11-12 KR KR1020127001647A patent/KR101282320B1/ko not_active Expired - Fee Related
- 2004-11-12 CA CA2805859A patent/CA2805859A1/en not_active Abandoned
- 2004-11-12 CN CN201010274020XA patent/CN101979412A/zh active Pending
- 2004-11-12 PL PL04817825T patent/PL1685152T3/pl unknown
- 2004-11-12 BR BRPI0416255-2A patent/BRPI0416255A/pt not_active IP Right Cessation
-
2006
- 2006-05-04 IL IL175422A patent/IL175422A0/en unknown
- 2006-05-10 ZA ZA200603733A patent/ZA200603733B/en unknown
-
2010
- 2010-07-13 IL IL206979A patent/IL206979A0/en unknown
- 2010-12-16 JP JP2010280298A patent/JP2011097946A/ja active Pending
- 2010-12-16 JP JP2010280299A patent/JP2011097947A/ja active Pending
-
2012
- 2012-02-13 JP JP2012028435A patent/JP2012139223A/ja active Pending
- 2012-07-05 CY CY20121100602T patent/CY1112893T1/el unknown
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