CA2805859A1 - Il-18 binding proteins - Google Patents

Il-18 binding proteins Download PDF

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Publication number
CA2805859A1
CA2805859A1 CA2805859A CA2805859A CA2805859A1 CA 2805859 A1 CA2805859 A1 CA 2805859A1 CA 2805859 A CA2805859 A CA 2805859A CA 2805859 A CA2805859 A CA 2805859A CA 2805859 A1 CA2805859 A1 CA 2805859A1
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CA
Canada
Prior art keywords
seq
residues
binding protein
human
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2805859A
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English (en)
French (fr)
Inventor
Tariq Ghayur
Boris Labkovsky
Jeffrey W. Voss
Larry Green
John Babcook
Xiao-Chi Jia
James Wieler
Jaspal Singh Kang
Brad Hedberg
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Abbott Laboratories
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Abbott Laboratories
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Publication date
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Publication of CA2805859A1 publication Critical patent/CA2805859A1/en
Abandoned legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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