JP2010536886A5 - - Google Patents

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Publication number
JP2010536886A5
JP2010536886A5 JP2010522103A JP2010522103A JP2010536886A5 JP 2010536886 A5 JP2010536886 A5 JP 2010536886A5 JP 2010522103 A JP2010522103 A JP 2010522103A JP 2010522103 A JP2010522103 A JP 2010522103A JP 2010536886 A5 JP2010536886 A5 JP 2010536886A5
Authority
JP
Japan
Prior art keywords
met
antigen
binding fragment
specific mab
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010522103A
Other languages
English (en)
Japanese (ja)
Other versions
JP4806469B2 (ja
JP2010536886A (ja
Filing date
Publication date
Priority claimed from US11/845,023 external-priority patent/US7892770B2/en
Application filed filed Critical
Publication of JP2010536886A publication Critical patent/JP2010536886A/ja
Publication of JP2010536886A5 publication Critical patent/JP2010536886A5/ja
Application granted granted Critical
Publication of JP4806469B2 publication Critical patent/JP4806469B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010522103A 2007-08-24 2008-08-25 ホルマリン固定およびパラフィン包埋された組織においてＭｅｔを結合するモノクローナル抗体および関連する方法 Expired - Fee Related JP4806469B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/845,023 2007-08-24
US11/845,023 US7892770B2 (en) 2007-08-24 2007-08-24 Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods
PCT/US2008/074249 WO2009029591A2 (en) 2007-08-24 2008-08-25 Monoclonal antibody which binds met in formalin-fixed and paraffin-embedded tissues and related methods

Publications (3)

Publication Number Publication Date
JP2010536886A JP2010536886A (ja) 2010-12-02
JP2010536886A5 true JP2010536886A5 (enExample) 2011-06-30
JP4806469B2 JP4806469B2 (ja) 2011-11-02

Family

ID=40193999

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010522103A Expired - Fee Related JP4806469B2 (ja) 2007-08-24 2008-08-25 ホルマリン固定およびパラフィン包埋された組織においてＭｅｔを結合するモノクローナル抗体および関連する方法

Country Status (6)

Country Link
US (2) US7892770B2 (enExample)
EP (1) EP2195345B1 (enExample)
JP (1) JP4806469B2 (enExample)
CA (1) CA2715103C (enExample)
ES (1) ES2386188T3 (enExample)
WO (1) WO2009029591A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7563584B2 (en) 2001-07-10 2009-07-21 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for detecting the activation state of multiple proteins in single cells
WO2006032044A2 (en) * 2004-09-15 2006-03-23 Microchip Biotechnologies, Inc. Microfluidic devices
US7892770B2 (en) * 2007-08-24 2011-02-22 Van Andel Research Institute Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods
EP2287197A1 (en) * 2009-08-21 2011-02-23 Pierre Fabre Medicament Anti-cMET antibody and its use for the detection and the diagnosis of cancer
GB201004551D0 (en) 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
US9169329B2 (en) * 2010-06-01 2015-10-27 Ludwig Institute For Cancer Research Antibodies directed to the receptor tyrosine kinase c-Met
EP2402370A1 (en) * 2010-06-29 2012-01-04 Pierre Fabre Médicament Novel antibody for the diagnosis and/or prognosis of cancer
EP3165538A1 (en) 2010-11-03 2017-05-10 Argen-X Nv Anti c-met antibodies
US20140348819A1 (en) 2011-06-24 2014-11-27 Dana-Farber Cancer Institute, Inc. Methods of Treating Cancer
EP2758430A4 (en) 2011-09-20 2015-06-03 Lilly Co Eli ANTI-C-MET ANTIBODY
EP2773660A2 (en) 2011-11-03 2014-09-10 Argen-X B.V. Chimeric human-camel antigens and their use
EP3560509B1 (en) 2011-12-22 2024-01-31 Children's Medical Center Corporation Saposin-a derived peptides and uses thereof
CA2869316C (en) * 2012-05-09 2016-12-20 Eli Lilly And Company Anti-c-met antibodies
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
EP3122900A1 (en) 2014-03-24 2017-02-01 F. Hoffmann-La Roche AG Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
MX378108B (es) 2014-09-16 2025-03-10 Servier Lab Anticuerpos anti-met y composiciones.
GB201521894D0 (en) 2015-12-11 2016-01-27 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against various cancers
MY196837A (en) 2015-12-11 2023-05-03 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against various cancers
TWI782930B (zh) 2016-11-16 2022-11-11 美商再生元醫藥公司 抗ｍｅｔ抗體，結合ｍｅｔ之雙特異性抗原結合分子及其使用方法
MX2021010265A (es) 2019-02-26 2021-09-23 Janssen Biotech Inc Terapias de combinacion y estratificacion de pacientes con anticuerpos anti-egfr/c-met biespecificos.
US11850248B2 (en) 2019-05-14 2023-12-26 Yuhan Corporation Therapies with 3rd generation EGFR tyrosine kinase inhibitors
MY208668A (en) 2019-05-14 2025-05-23 Janssen Biotech Inc Combination therapies with bispecific anti-egfr/c-met antibodies and 3rd generation egfr tyrosine kinase inhibitors
CN114340684B (zh) 2019-09-16 2025-09-12 瑞泽恩制药公司 用于免疫pet成像的放射性标记的met结合蛋白
BR112022015140A2 (pt) 2020-02-12 2022-10-11 Janssen Biotech Inc Tratamento de pacientes que têm mutações de salto do éxon 14 de c-met

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5917017A (en) * 1994-06-08 1999-06-29 President And Fellows Of Harvard College Diphtheria toxin vaccines bearing a mutated R domain
KR20030094281A (ko) * 2001-03-12 2003-12-11 모노젠, 인크. 세포에 기초한 질병상태의 검출 및 질병상태의 구별
US7892770B2 (en) * 2007-08-24 2011-02-22 Van Andel Research Institute Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods

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