JP2010536787A5 - - Google Patents

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Publication number
JP2010536787A5
JP2010536787A5 JP2010521194A JP2010521194A JP2010536787A5 JP 2010536787 A5 JP2010536787 A5 JP 2010536787A5 JP 2010521194 A JP2010521194 A JP 2010521194A JP 2010521194 A JP2010521194 A JP 2010521194A JP 2010536787 A5 JP2010536787 A5 JP 2010536787A5
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JP
Japan
Prior art keywords
disease
nucleotide
deoxy
substituted
hydroxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010521194A
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English (en)
Japanese (ja)
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JP2010536787A (ja
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Publication date
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Priority claimed from PCT/US2008/073280 external-priority patent/WO2009023819A2/en
Publication of JP2010536787A publication Critical patent/JP2010536787A/ja
Publication of JP2010536787A5 publication Critical patent/JP2010536787A5/ja
Withdrawn legal-status Critical Current

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JP2010521194A 2007-08-15 2008-08-15 Toll様受容体モジュレータ Withdrawn JP2010536787A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95589507P 2007-08-15 2007-08-15
PCT/US2008/073280 WO2009023819A2 (en) 2007-08-15 2008-08-15 Toll like receptor modulators

Publications (2)

Publication Number Publication Date
JP2010536787A JP2010536787A (ja) 2010-12-02
JP2010536787A5 true JP2010536787A5 (enExample) 2011-09-29

Family

ID=40351489

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010521194A Withdrawn JP2010536787A (ja) 2007-08-15 2008-08-15 Toll様受容体モジュレータ

Country Status (9)

Country Link
US (1) US8853375B2 (enExample)
EP (1) EP2179061B1 (enExample)
JP (1) JP2010536787A (enExample)
KR (1) KR20100066512A (enExample)
CN (1) CN101821412A (enExample)
AU (1) AU2008286735A1 (enExample)
CA (1) CA2694973A1 (enExample)
MX (1) MX2010001785A (enExample)
WO (1) WO2009023819A2 (enExample)

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US8877722B2 (en) 2011-03-25 2014-11-04 Idera Pharmaceuticals, Inc. Compositions for inhibiting gene expression and uses thereof
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CN107365339A (zh) 2011-07-19 2017-11-21 波涛生命科学有限公司 合成官能化核酸的方法
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DK2872147T3 (da) 2012-07-13 2023-02-20 Wave Life Sciences Ltd Fremgangsmåde til fremstilling af kirale oligonukleotider
SG11201500243WA (en) * 2012-07-13 2015-04-29 Shin Nippon Biomedical Lab Ltd Chiral nucleic acid adjuvant
WO2014010250A1 (en) 2012-07-13 2014-01-16 Chiralgen, Ltd. Asymmetric auxiliary group
US20150247141A1 (en) * 2012-09-14 2015-09-03 Rana Therapeutics, Inc. Multimeric oligonucleotide compounds
CN103845731B (zh) * 2012-12-05 2015-12-02 复旦大学 抗st2/il-1r4抗体在制备防治瘙痒药物中的应用
CN103845730B (zh) * 2012-12-05 2015-12-09 复旦大学 抗st2/il-1 r4抗体在制备镇痛药物中的用途
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CN105541947A (zh) * 2016-01-11 2016-05-04 中国人民解放军第三军医大学第一附属医院 拮抗tlr7/8及tlr9活化的药物分子及用途
CN105597079A (zh) * 2016-01-11 2016-05-25 中国人民解放军第三军医大学第一附属医院 用于治疗银屑病的药物
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JP2021502381A (ja) 2017-11-08 2021-01-28 プレジデント アンド フェローズ オブ ハーバード カレッジ ウイルスベクター誘発性炎症反応を阻害するための組成物および方法
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PL1794174T3 (pl) * 2004-09-01 2012-11-30 Dynavax Tech Corp Sposoby i kompozycje do hamowania wrodzonych odpowiedzi immunologicznych i autoodporności
ES2544877T3 (es) * 2005-10-12 2015-09-04 Idera Pharmaceuticals Compuestos oligonucleótidos inmuno reguladores (IRO) para modular la respuesta inmune basada en receptor semejante a Toll

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