JP2016510213A5 - - Google Patents

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Publication number
JP2016510213A5
JP2016510213A5 JP2015551852A JP2015551852A JP2016510213A5 JP 2016510213 A5 JP2016510213 A5 JP 2016510213A5 JP 2015551852 A JP2015551852 A JP 2015551852A JP 2015551852 A JP2015551852 A JP 2015551852A JP 2016510213 A5 JP2016510213 A5 JP 2016510213A5
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JP
Japan
Prior art keywords
pharmaceutical composition
disease
iro compound
composition according
iro
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JP2015551852A
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English (en)
Japanese (ja)
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JP6385957B2 (ja
JP2016510213A (ja
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Priority claimed from PCT/US2014/010599 external-priority patent/WO2014110081A1/en
Publication of JP2016510213A publication Critical patent/JP2016510213A/ja
Publication of JP2016510213A5 publication Critical patent/JP2016510213A5/ja
Application granted granted Critical
Publication of JP6385957B2 publication Critical patent/JP6385957B2/ja
Expired - Fee Related legal-status Critical Current
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JP2015551852A 2013-01-08 2014-01-08 トール様受容体に基づく免疫応答を調節するための免疫調節オリゴヌクレオチド（ｉｒｏ）化合物 Expired - Fee Related JP6385957B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361750014P 2013-01-08 2013-01-08
US61/750,014 2013-01-08
PCT/US2014/010599 WO2014110081A1 (en) 2013-01-08 2014-01-08 Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

Publications (3)

Publication Number Publication Date
JP2016510213A JP2016510213A (ja) 2016-04-07
JP2016510213A5 true JP2016510213A5 (enExample) 2016-12-28
JP6385957B2 JP6385957B2 (ja) 2018-09-05

Family

ID=51061112

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015551852A Expired - Fee Related JP6385957B2 (ja) 2013-01-08 2014-01-08 トール様受容体に基づく免疫応答を調節するための免疫調節オリゴヌクレオチド（ｉｒｏ）化合物

Country Status (9)

Country Link
US (3) US9260719B2 (enExample)
EP (1) EP2943251B1 (enExample)
JP (1) JP6385957B2 (enExample)
KR (1) KR101898177B1 (enExample)
AU (2) AU2014205544B2 (enExample)
BR (1) BR112015016420B1 (enExample)
CA (1) CA2896537C (enExample)
HK (1) HK1214191A1 (enExample)
WO (1) WO2014110081A1 (enExample)

Families Citing this family (8)

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AU2014205544B2 (en) * 2013-01-08 2018-07-12 Idera Pharmaceuticals, Inc. Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
WO2016130832A1 (en) 2015-02-13 2016-08-18 Idera Pharmaceuticals, Inc. Toll-like receptor 9 antagonist and methods of use thereof
US20190046638A1 (en) 2016-04-01 2019-02-14 Checkmate Pharmaceuticals, Inc. Fc RECEPTOR-MEDIATED DRUG DELIVERY
EP3468605A4 (en) 2016-06-08 2020-01-08 President and Fellows of Harvard College MANIPULATED VIRAL VECTOR TO REDUCE INDUCTION OF IGNITION AND IMMUNE REACTIONS
KR102596343B1 (ko) * 2016-11-23 2023-10-31 베를린 큐어스 게엠베하 TLR9 활성화의 저해 및/또는 억제에 사용되는 압타머(aptamer)
JP2021502381A (ja) 2017-11-08 2021-01-28 プレジデント アンド フェローズ オブ ハーバード カレッジ ウイルスベクター誘発性炎症反応を阻害するための組成物および方法
WO2019160866A2 (en) 2018-02-13 2019-08-22 Checkmate Pharmaceuticals, Inc. Compositions and methods for tumor immunotherapy
BR112020020479A2 (pt) 2018-04-09 2021-01-12 Checkmate Pharmaceuticals Empacotamento de oligonucleotídeos em partículas similares a vírus

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US7176296B2 (en) * 2001-04-30 2007-02-13 Idera Pharmaceuticals, Inc. Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
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WO2003035836A2 (en) * 2001-10-24 2003-05-01 Hybridon Inc. Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
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US8383598B2 (en) 2005-10-12 2013-02-26 Idera Pharmaceuticals, Inc. Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
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US8426375B2 (en) 2005-10-12 2013-04-23 Idera Pharmaceuticals, Inc. Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
ES2544877T3 (es) * 2005-10-12 2015-09-04 Idera Pharmaceuticals Compuestos oligonucleótidos inmuno reguladores (IRO) para modular la respuesta inmune basada en receptor semejante a Toll
US7776834B2 (en) * 2005-11-07 2010-08-17 Idera Pharmaceuticals, Inc. Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides
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