AU2014205544B2 - Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response - Google Patents

Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Download PDF

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Publication number
AU2014205544B2
AU2014205544B2 AU2014205544A AU2014205544A AU2014205544B2 AU 2014205544 B2 AU2014205544 B2 AU 2014205544B2 AU 2014205544 A AU2014205544 A AU 2014205544A AU 2014205544 A AU2014205544 A AU 2014205544A AU 2014205544 B2 AU2014205544 B2 AU 2014205544B2
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Prior art keywords
disease
pharmaceutical composition
mammal
iro compound
iro
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AU2014205544A
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AU2014205544A2 (en
AU2014205544A1 (en
Inventor
Sudhir Agrawal
Ekambar R. Kandimalla
Ireneusz Nowak
Daqing Wang
Dong Yu
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Aceragen Inc
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Idera Pharmaceuticals Inc
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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AU2014205544A 2013-01-08 2014-01-08 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Ceased AU2014205544B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2018247308A AU2018247308B2 (en) 2013-01-08 2018-10-12 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361750014P 2013-01-08 2013-01-08
US61/750,014 2013-01-08
PCT/US2014/010599 WO2014110081A1 (en) 2013-01-08 2014-01-08 Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

Related Child Applications (1)

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AU2018247308A Division AU2018247308B2 (en) 2013-01-08 2018-10-12 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

Publications (3)

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AU2014205544A1 AU2014205544A1 (en) 2015-07-23
AU2014205544A2 AU2014205544A2 (en) 2015-08-06
AU2014205544B2 true AU2014205544B2 (en) 2018-07-12

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AU2018247308A Ceased AU2018247308B2 (en) 2013-01-08 2018-10-12 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

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US (3) US9260719B2 (enExample)
EP (1) EP2943251B1 (enExample)
JP (1) JP6385957B2 (enExample)
KR (1) KR101898177B1 (enExample)
AU (2) AU2014205544B2 (enExample)
BR (1) BR112015016420B1 (enExample)
CA (1) CA2896537C (enExample)
HK (1) HK1214191A1 (enExample)
WO (1) WO2014110081A1 (enExample)

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AU2014205544B2 (en) * 2013-01-08 2018-07-12 Idera Pharmaceuticals, Inc. Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
WO2016130832A1 (en) 2015-02-13 2016-08-18 Idera Pharmaceuticals, Inc. Toll-like receptor 9 antagonist and methods of use thereof
US20190046638A1 (en) 2016-04-01 2019-02-14 Checkmate Pharmaceuticals, Inc. Fc RECEPTOR-MEDIATED DRUG DELIVERY
EP3468605A4 (en) 2016-06-08 2020-01-08 President and Fellows of Harvard College MANIPULATED VIRAL VECTOR TO REDUCE INDUCTION OF IGNITION AND IMMUNE REACTIONS
KR102596343B1 (ko) * 2016-11-23 2023-10-31 베를린 큐어스 게엠베하 TLR9 활성화의 저해 및/또는 억제에 사용되는 압타머(aptamer)
JP2021502381A (ja) 2017-11-08 2021-01-28 プレジデント アンド フェローズ オブ ハーバード カレッジ ウイルスベクター誘発性炎症反応を阻害するための組成物および方法
WO2019160866A2 (en) 2018-02-13 2019-08-22 Checkmate Pharmaceuticals, Inc. Compositions and methods for tumor immunotherapy
BR112020020479A2 (pt) 2018-04-09 2021-01-12 Checkmate Pharmaceuticals Empacotamento de oligonucleotídeos em partículas similares a vírus

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