JP2012176990A5 - - Google Patents
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- Publication number
- JP2012176990A5 JP2012176990A5 JP2012137900A JP2012137900A JP2012176990A5 JP 2012176990 A5 JP2012176990 A5 JP 2012176990A5 JP 2012137900 A JP2012137900 A JP 2012137900A JP 2012137900 A JP2012137900 A JP 2012137900A JP 2012176990 A5 JP2012176990 A5 JP 2012176990A5
- Authority
- JP
- Japan
- Prior art keywords
- calcium salt
- formulation
- used according
- active ingredient
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 159000000007 calcium salts Chemical class 0.000 claims 17
- 238000009472 formulation Methods 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 16
- 239000004480 active ingredient Substances 0.000 claims 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 230000003115 biocidal effect Effects 0.000 claims 2
- 229940124630 bronchodilator Drugs 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical group [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims 1
- 102000053642 Catalytic RNA Human genes 0.000 claims 1
- 108090000994 Catalytic RNA Proteins 0.000 claims 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 230000000692 anti-sense effect Effects 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 239000003434 antitussive agent Substances 0.000 claims 1
- 229940124584 antitussives Drugs 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000001110 calcium chloride Substances 0.000 claims 1
- 229910001628 calcium chloride Inorganic materials 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003172 expectorant agent Substances 0.000 claims 1
- 230000003419 expectorant effect Effects 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 230000003843 mucus production Effects 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000007523 nucleic acids Chemical group 0.000 claims 1
- 229920001542 oligosaccharide Polymers 0.000 claims 1
- 150000002482 oligosaccharides Chemical class 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 108091092562 ribozyme Proteins 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68235605P | 2005-05-18 | 2005-05-18 | |
| US60/682,356 | 2005-05-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512543A Division JP2008540680A (ja) | 2005-05-18 | 2006-05-18 | 粘膜内壁の生物物理学的な性質を変化させる製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012176990A JP2012176990A (ja) | 2012-09-13 |
| JP2012176990A5 true JP2012176990A5 (enExample) | 2012-10-25 |
Family
ID=37401509
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512543A Pending JP2008540680A (ja) | 2005-05-18 | 2006-05-18 | 粘膜内壁の生物物理学的な性質を変化させる製剤 |
| JP2012137900A Pending JP2012176990A (ja) | 2005-05-18 | 2012-06-19 | 粘膜内壁の生物物理学的な性質を変化させる製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512543A Pending JP2008540680A (ja) | 2005-05-18 | 2006-05-18 | 粘膜内壁の生物物理学的な性質を変化させる製剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20070053844A1 (enExample) |
| EP (3) | EP1906922A2 (enExample) |
| JP (2) | JP2008540680A (enExample) |
| KR (1) | KR20080018872A (enExample) |
| CN (2) | CN102327285A (enExample) |
| AU (1) | AU2006247077A1 (enExample) |
| BR (1) | BRPI0609924A2 (enExample) |
| CA (1) | CA2608752A1 (enExample) |
| EA (1) | EA016072B1 (enExample) |
| IL (1) | IL187427A0 (enExample) |
| NO (1) | NO20076086L (enExample) |
| NZ (2) | NZ564110A (enExample) |
| WO (1) | WO2006125153A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050207983A1 (en) | 2004-03-05 | 2005-09-22 | Pulmatrix, Inc. | Formulations decreasing particle exhalation |
| JP2012522009A (ja) * | 2009-03-26 | 2012-09-20 | パルマトリックス，インコーポレイテッド | 肺炎および人工呼吸器関連気管気管支炎を治療および予防するための方法 |
| US20120064126A1 (en) * | 2009-03-26 | 2012-03-15 | Pulmatrix, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| WO2010111640A2 (en) * | 2009-03-26 | 2010-09-30 | Pulmatrix, Inc. | Anti-influenza formulations and methods |
| KR20120015295A (ko) * | 2009-03-26 | 2012-02-21 | 풀매트릭스 인코퍼레이티드 | 점막 내층의 생물물리학적 성질의 변경을 위한 구연산 칼슘 및 젖산 칼슘 제형 |
| RU2011137961A (ru) * | 2009-03-26 | 2013-05-10 | Пулмэтрикс, Инк. | Фармацевтические составы и способы лечения инфекций дыхательных путей |
| EP2448571B1 (en) | 2010-08-30 | 2013-06-12 | Pulmatrix, Inc. | Respirably dry powder comprising calcium lactate, sodium chloride and leucine |
| JP5877201B2 (ja) | 2010-08-30 | 2016-03-02 | パルマトリックス，インコーポレイテッド | 肺疾患を治療するための乾燥粉末製剤および方法 |
| MX354828B (es) | 2010-09-29 | 2018-03-22 | Pulmatrix Operating Co Inc | Polvos secos de cationes metálicos monovalentes para inhalación. |
| ES2710537T3 (es) | 2010-09-29 | 2019-04-25 | Pulmatrix Operating Co Inc | Polvos secos catiónicos |
| US20140336159A1 (en) | 2011-10-07 | 2014-11-13 | Pulmatrix, Inc. | Methods for treating and diagnosing respiratory tract infections |
| CN109999013A (zh) | 2012-02-29 | 2019-07-12 | 普马特里克斯营业公司 | 可吸入干粉剂 |
| JP6473738B2 (ja) | 2013-04-01 | 2019-02-20 | パルマトリックス，インコーポレイテッド | チオトロピウム乾燥粉末 |
| US9987235B2 (en) * | 2013-08-01 | 2018-06-05 | Nicholas L. Abbott | Methods and compositions for modifying mucous membranes |
| CA2965759C (en) | 2014-10-31 | 2023-12-12 | Glaxosmithkline Intellectual Property Development Limited | Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials |
| CA3004908A1 (en) * | 2015-11-18 | 2017-05-26 | The Board Of Trustees Of The Leland Stanford Junior University | B-1a lymphocyte and/or macrophage targeting and activation to treat medical conditions with inflammatory or autoimmune components |
| KR20200108862A (ko) * | 2018-01-11 | 2020-09-21 | 엠피세마 솔루션스 비브이 | 폐기종과 다른 형태의 ｃｏｐｄ의 치료를 위한 조성물과 방법 |
| EP3846825A4 (en) | 2018-09-05 | 2022-11-02 | Sensory Cloud, LLC | FORMULATIONS AND COMPOSITIONS FOR ORTHO- AND/OR RETRO-NASAL DELIVERY AND RELATED SYSTEMS, METHODS AND ARTICLES |
| US12128067B2 (en) | 2018-11-29 | 2024-10-29 | Yildiz Teknik Universitesi | Nasal solution with closed basin natural spring water characteristic and method for obtaining said nasal solution |
| US20230218661A1 (en) * | 2022-01-10 | 2023-07-13 | Sensory Cloud, Inc. | Isotonic or hypertonic salt-based compositions, treatments, devices, and articles for delivery of same to larynx |
| US20220000767A1 (en) * | 2020-07-06 | 2022-01-06 | Sensory Cloud, Inc. | Nasal hygiene compositions, antimicrobial treatments, devices, and articles for delivery of same to the nose, trachea and main bronchi |
| US20220051592A1 (en) * | 2020-08-17 | 2022-02-17 | Massachusetts Institute Of Technology | Respiratory system simulator systems and methods |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3229179C2 (de) * | 1982-08-05 | 1986-04-17 | A. Nattermann & Cie GmbH, 5000 Köln | Lungensurfactant |
| US4637815A (en) * | 1985-08-06 | 1987-01-20 | Lemole Gerald M | Irrigational hemostatic solution |
| US5230884A (en) * | 1990-09-11 | 1993-07-27 | University Of Wales College Of Cardiff | Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations |
| US5175152A (en) * | 1990-09-28 | 1992-12-29 | Singh Nikhilesh N | Composition containing ephedrine base and alkyl salicylate for the delivery of ephedrine base in vapor form |
| US5571535A (en) * | 1990-11-30 | 1996-11-05 | Flowers; Marianne | Treatment of topical infections |
| US5466680A (en) * | 1992-03-26 | 1995-11-14 | Cytologics, Inc. | Method and compositions for enhancing white blood cell functioning on a mucosal or cutaneous surface |
| US5898037A (en) * | 1992-11-13 | 1999-04-27 | Marx; Alvin J. | Formulations of magnesium compounds for local application and methods of treatment using the same |
| US5709202A (en) | 1993-05-21 | 1998-01-20 | Aradigm Corporation | Intrapulmonary delivery of aerosolized formulations |
| AUPM411494A0 (en) * | 1994-02-25 | 1994-03-24 | Central Sydney Area Health Service | Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum |
| US5633003A (en) * | 1994-03-31 | 1997-05-27 | Cantor; Jerome O. | Use of intratracheally administered hyaluronic acid to ameliorate emphysema |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| KR100386392B1 (ko) * | 1994-10-14 | 2003-10-11 | 야마노우치세이야쿠 가부시키가이샤 | 아졸유도체및이를포함하는약제학적조성물 |
| AU3705695A (en) * | 1994-10-26 | 1996-05-23 | Wellcome Foundation Limited, The | Pharmaceutical composition comprising atovaquone |
| US5654007A (en) * | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| US5628984A (en) * | 1995-07-31 | 1997-05-13 | University Of North Carolina At Chapel Hill | Method of detecting lung disease |
| US6083922A (en) * | 1996-04-02 | 2000-07-04 | Pathogenesis, Corp. | Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis |
| USRE37053E1 (en) * | 1996-05-24 | 2001-02-13 | Massachusetts Institute Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| US6254854B1 (en) * | 1996-05-24 | 2001-07-03 | The Penn Research Foundation | Porous particles for deep lung delivery |
| US5985309A (en) * | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| US5855913A (en) * | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| DE19653969A1 (de) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
| HRP20000666A2 (en) * | 1998-04-08 | 2001-08-31 | Lilly Co Eli | Pulmonary and nasal delivery of raloxifene |
| US5883084A (en) * | 1998-06-08 | 1999-03-16 | Clarion Pharmaceuticals Inc. | Treatment of respiratory diseases utilizing α-tocopheryl-phosphocholine |
| FR2780285B1 (fr) * | 1998-06-29 | 2001-10-05 | Goemar Lab Sa | Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicaments anti-inflammatoires a base de ces solutions |
| US6333051B1 (en) * | 1998-09-03 | 2001-12-25 | Supratek Pharma, Inc. | Nanogel networks and biological agent compositions thereof |
| EP1173245B1 (en) * | 1999-05-03 | 2004-09-01 | Battelle Memorial Institute | Compositions for aerosolization and inhalation |
| US6858199B1 (en) * | 2000-06-09 | 2005-02-22 | Advanced Inhalation Research, Inc. | High efficient delivery of a large therapeutic mass aerosol |
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| AU2002245181B2 (en) * | 2000-12-21 | 2006-06-29 | Nektar Therapeutics | Pulmonary delivery of polyene antifungal agents |
| US6667344B2 (en) * | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| US20030232019A1 (en) * | 2002-02-22 | 2003-12-18 | Advanced Inhalation Research, Inc. | Inhalable formulations for sustained release |
| EP1531795A4 (en) * | 2002-05-02 | 2011-02-23 | Harvard College | FORMULATIONS FOR LIMITING THE RETENTION OF LUNG INFECTIONS |
| WO2003094900A1 (en) * | 2002-05-13 | 2003-11-20 | Alexza Molecular Delivery Corporation | Delivery of drug amines through an inhalation route |
| EP1511467A1 (en) * | 2002-06-10 | 2005-03-09 | Elan Pharma International Limited | Nanoparticulate polycosanol formulations and novel polycosanol combinations |
| US7534781B2 (en) * | 2003-03-21 | 2009-05-19 | Dsm Ip Assets B.V. | Crystalline amoxicillin trihydrate powder |
| JP2009514779A (ja) * | 2003-07-11 | 2009-04-09 | グラクソ グループ リミテッド | 医薬製剤 |
| GB0324897D0 (en) * | 2003-10-24 | 2003-11-26 | Glaxo Group Ltd | Composition |
| US20050207983A1 (en) | 2004-03-05 | 2005-09-22 | Pulmatrix, Inc. | Formulations decreasing particle exhalation |
| SE528121C2 (sv) * | 2004-03-29 | 2006-09-05 | Mederio Ag | Preparering av torrpulver för på förhand uppmätt DPI |
| US20070275091A1 (en) * | 2004-03-30 | 2007-11-29 | Malcolm King | Compositions And Methods For Improved Mucus Function |
| WO2006014930A2 (en) * | 2004-07-26 | 2006-02-09 | Cotherix, Inc. | Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation |
| US20070202051A1 (en) * | 2006-02-10 | 2007-08-30 | Pari Gmbh | Aerosols for sinunasal drug delivery |
| GB0818476D0 (en) * | 2008-10-09 | 2008-11-12 | Vectura Delivery Device Ltd | Inhaler |
| WO2010111640A2 (en) * | 2009-03-26 | 2010-09-30 | Pulmatrix, Inc. | Anti-influenza formulations and methods |
-
2006
- 2006-05-18 WO PCT/US2006/019443 patent/WO2006125153A2/en not_active Ceased
- 2006-05-18 EP EP06770654A patent/EP1906922A2/en not_active Withdrawn
- 2006-05-18 CN CN2011102255478A patent/CN102327285A/zh active Pending
- 2006-05-18 NZ NZ564110A patent/NZ564110A/en unknown
- 2006-05-18 US US11/419,165 patent/US20070053844A1/en not_active Abandoned
- 2006-05-18 AU AU2006247077A patent/AU2006247077A1/en not_active Abandoned
- 2006-05-18 BR BRPI0609924-6A patent/BRPI0609924A2/pt not_active IP Right Cessation
- 2006-05-18 JP JP2008512543A patent/JP2008540680A/ja active Pending
- 2006-05-18 KR KR1020077027567A patent/KR20080018872A/ko not_active Ceased
- 2006-05-18 EP EP10014830A patent/EP2308469A1/en not_active Withdrawn
- 2006-05-18 CA CA002608752A patent/CA2608752A1/en not_active Abandoned
- 2006-05-18 NZ NZ593475A patent/NZ593475A/xx unknown
- 2006-05-18 CN CNA2006800261749A patent/CN101237853A/zh active Pending
- 2006-05-18 EA EA200702520A patent/EA016072B1/ru not_active IP Right Cessation
- 2006-05-18 EP EP11177874A patent/EP2402001A1/en not_active Withdrawn
-
2007
- 2007-11-15 IL IL187427A patent/IL187427A0/en unknown
- 2007-11-27 NO NO20076086A patent/NO20076086L/no not_active Application Discontinuation
-
2012
- 2012-06-19 JP JP2012137900A patent/JP2012176990A/ja active Pending
-
2014
- 2014-11-14 US US14/541,648 patent/US20150196589A1/en not_active Abandoned
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