JP2010531136A5 - - Google Patents
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- Publication number
- JP2010531136A5 JP2010531136A5 JP2010511461A JP2010511461A JP2010531136A5 JP 2010531136 A5 JP2010531136 A5 JP 2010531136A5 JP 2010511461 A JP2010511461 A JP 2010511461A JP 2010511461 A JP2010511461 A JP 2010511461A JP 2010531136 A5 JP2010531136 A5 JP 2010531136A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- plant
- nucleotide sequence
- interest
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002773 nucleotide Substances 0.000 claims description 53
- 125000003729 nucleotide group Chemical group 0.000 claims description 53
- 102000004169 proteins and genes Human genes 0.000 claims description 53
- 108090000623 proteins and genes Proteins 0.000 claims description 53
- 150000007523 nucleic acids Chemical class 0.000 claims description 23
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 16
- 108020004707 nucleic acids Proteins 0.000 claims description 11
- 102000039446 nucleic acids Human genes 0.000 claims description 11
- 230000013595 glycosylation Effects 0.000 claims description 10
- 238000006206 glycosylation reaction Methods 0.000 claims description 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 3
- 238000000034 method Methods 0.000 claims 27
- 230000001105 regulatory effect Effects 0.000 claims 17
- 108090000051 Plastocyanin Proteins 0.000 claims 8
- 230000002194 synthesizing effect Effects 0.000 claims 7
- 230000004988 N-glycosylation Effects 0.000 claims 6
- 230000003197 catalytic effect Effects 0.000 claims 5
- 102100023315 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase Human genes 0.000 claims 4
- 108010056664 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase Proteins 0.000 claims 4
- 230000033581 fucosylation Effects 0.000 claims 4
- 150000004676 glycans Chemical class 0.000 claims 4
- 102100024775 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Human genes 0.000 claims 3
- 101000747588 Homo sapiens UDP-glucuronosyltransferase 1-6 Proteins 0.000 claims 3
- 101000841498 Homo sapiens UDP-glucuronosyltransferase 1A1 Proteins 0.000 claims 3
- 108010046068 N-Acetyllactosamine Synthase Proteins 0.000 claims 3
- 102100029151 UDP-glucuronosyltransferase 1A10 Human genes 0.000 claims 3
- 108010087667 beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase Proteins 0.000 claims 3
- 108060003306 Galactosyltransferase Proteins 0.000 claims 2
- 102000030902 Galactosyltransferase Human genes 0.000 claims 2
- 230000030279 gene silencing Effects 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94434407P | 2007-06-15 | 2007-06-15 | |
| US60/944,344 | 2007-06-15 | ||
| PCT/CA2008/001139 WO2008151440A1 (en) | 2007-06-15 | 2008-06-13 | Modifying glycoprotein production in plants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010531136A JP2010531136A (ja) | 2010-09-24 |
| JP2010531136A5 true JP2010531136A5 (enExample) | 2011-07-28 |
| JP5783720B2 JP5783720B2 (ja) | 2015-09-24 |
Family
ID=40129187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010511461A Expired - Fee Related JP5783720B2 (ja) | 2007-06-15 | 2008-06-13 | 植物での糖タンパク質生成の改変 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20110008837A1 (enExample) |
| EP (1) | EP2155880B1 (enExample) |
| JP (1) | JP5783720B2 (enExample) |
| KR (2) | KR101385050B1 (enExample) |
| CN (3) | CN103382487A (enExample) |
| AU (1) | AU2008261527C1 (enExample) |
| BR (1) | BRPI0812538B1 (enExample) |
| CA (2) | CA2700180C (enExample) |
| DK (1) | DK2155880T3 (enExample) |
| EG (1) | EG26600A (enExample) |
| ES (1) | ES2624776T3 (enExample) |
| HU (1) | HUE031698T2 (enExample) |
| IL (1) | IL202568A (enExample) |
| MA (1) | MA31516B1 (enExample) |
| MX (1) | MX2009013665A (enExample) |
| NZ (2) | NZ598417A (enExample) |
| PL (1) | PL2155880T3 (enExample) |
| PT (1) | PT2155880T (enExample) |
| RU (2) | RU2499053C2 (enExample) |
| SG (1) | SG185249A1 (enExample) |
| SI (1) | SI2155880T1 (enExample) |
| TN (1) | TN2009000512A1 (enExample) |
| WO (1) | WO2008151440A1 (enExample) |
| ZA (1) | ZA201000207B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| CN103122354B (zh) | 2007-11-27 | 2018-03-23 | 麦迪卡格公司 | 表达血凝素之转基因植物中生产的重组流感病毒样颗粒(vlp) |
| US8771703B2 (en) | 2008-07-08 | 2014-07-08 | Medicago Inc. | Soluble recombinant influenza antigens |
| AU2009270404B2 (en) | 2008-07-18 | 2015-01-29 | Medicago Inc. | New influenza virus immunizing epitope |
| CA2762042C (en) | 2009-06-24 | 2012-11-20 | Medicago Inc. | Chimeric influenza virus-like particles comprising hemagglutinin |
| HRP20171564T1 (hr) | 2009-09-22 | 2017-11-17 | Medicago Inc. | Postupak za pripremu biljnih čestica sličnih virusu (vlp) |
| TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
| CA2839932C (en) * | 2011-06-07 | 2022-07-05 | Ibio, Inc. | In vivo de-glycosylation of recombinant proteins by co-expression with pngase f |
| EP2551348B1 (en) | 2011-07-29 | 2014-09-24 | Icon Genetics GmbH | Production of galactosylated N-glycans in plants |
| SI2760882T1 (sl) | 2011-09-30 | 2023-10-30 | Medicago Inc. | Povečanje količine virusom podobnih delcev v rastlinah |
| WO2013169009A1 (ko) * | 2012-05-08 | 2013-11-14 | 경상대학교 산학협력단 | 고-만노오스형 n-글라이칸을 생산하는 식물체 및 이를 이용한 고-만노오스형 n-글라이칸의 생산방법 |
| JP2016516415A (ja) | 2013-03-28 | 2016-06-09 | メディカゴ インコーポレイテッド | 植物におけるインフルエンザウイルス様粒子の生成 |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| JP6788582B2 (ja) | 2014-07-11 | 2020-11-25 | メディカゴ インコーポレイテッド | 植物におけるタンパク質生産の改変 |
| EA038931B9 (ru) | 2014-11-20 | 2022-02-18 | Йиссум Рисерч Дивелопмент Компани Оф Зе Хебрю Юниверсити Оф Иерусалим Лтд. | Композиции и способы получения полипептидов с модифицированным профилем гликозилирования в клетках растений |
| CA3045173A1 (en) | 2016-12-01 | 2018-06-07 | Plantform Corporation | Transgenic plant with reduced fucosyltransferase and xylosyltransferase activity |
| WO2019049111A1 (en) * | 2017-09-11 | 2019-03-14 | R. J. Reynolds Tobacco Company | METHODS AND COMPOSITIONS FOR INCREASING THE EXPRESSION OF GENES OF INTEREST IN A PLANT BY CO-EXPRESSION WITH P21 |
| JP7566045B2 (ja) * | 2021-01-15 | 2024-10-11 | デンカ株式会社 | 栽培条件を決定する方法、及び目的タンパク質又は目的ペプチドの製造方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312746A (en) * | 1993-01-08 | 1994-05-17 | Life Technologies, Inc. | Cloning and expressing restriction endonucleases and modification methylases from caryophanon |
| GB9524350D0 (en) * | 1995-11-29 | 1996-01-31 | Lynxvale Ltd | Enhancer-increased gene expression in plants |
| US5945326A (en) * | 1997-03-20 | 1999-08-31 | New England Biolabs, Inc. | Method for cloning and producing the Spel restriction endonuclease |
| ATE475714T1 (de) * | 1998-12-09 | 2010-08-15 | Phyton Holdings Llc | Verfahren zur herstellung von glycoprotein mit menschlichem glycosylierungsbild |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| DE60024658T2 (de) * | 1999-10-04 | 2006-08-24 | Medicago Inc., Sainte Foy | Promotor zur regulierung von fremdgenexpression |
| WO2001029242A2 (en) * | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
| ES2349427T3 (es) * | 1999-10-26 | 2011-01-03 | Stichting Dienst Landbouwkundig Onderzoek | Glicosilación de tipo mamífero en plantas. |
| WO2001031045A1 (en) * | 1999-10-26 | 2001-05-03 | Plant Research International B.V. | Mammalian-type glycosylation in plants |
| CN100385006C (zh) * | 2001-01-19 | 2008-04-30 | 陶氏化学公司 | 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法 |
| US20030035774A1 (en) | 2001-07-18 | 2003-02-20 | Adjei Akwete L. | Salt/ion pair medicinal aerosol formulation |
| CA2455365C (en) * | 2001-08-03 | 2014-07-29 | Glycart Biotechnology Ag | Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity |
| HUE050222T2 (hu) * | 2002-02-13 | 2020-11-30 | Wisconsin Alumni Res Found | Szignál influenzavírus-vektorok pakolására |
| JP4532118B2 (ja) * | 2002-03-19 | 2010-08-25 | スティヒティング ディーンスト ランドバウクンディフ オンデルズーク | 植物体内のグリカンプロセシングの最適化 |
| EP1485492B1 (en) * | 2002-03-19 | 2011-12-21 | Stichting Dienst Landbouwkundig Onderzoek | Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta(1,4)-n-acetylglucosaminyltransferase iii) expression in plants |
| PL224786B1 (pl) * | 2003-01-22 | 2017-01-31 | Glycart Biotechnology Ag | Wyizolowany kwas nukleinowy, ssaczy wektor ekspresyjny, komórki gospodarza, fuzja polipeptydowa i sposób jej wytwarzania, sposoby in vitro i ex vivo modyfikowania profilu glikozylacji polipeptydu wytwarzanego przez komórki gospodarza |
| CN1761746B (zh) * | 2003-01-22 | 2016-03-23 | 罗氏格黎卡特股份公司 | 融合构建体及其用来生产Fc受体结合亲和性和效应子功能提高的抗体的用途 |
| DE602004028004D1 (de) * | 2003-05-05 | 2010-08-19 | Thompson Boyce Plant Res | Vektoren und zellen zur herstellung von aus transgenen pflanzen gewonnenen immunprotektiven zusammensetzungen |
| JP2006212019A (ja) * | 2004-04-30 | 2006-08-17 | National Institute Of Agrobiological Sciences | 植物を用いたユビキノン−１０の製造方法 |
-
2008
- 2008-06-13 RU RU2010101024/10A patent/RU2499053C2/ru active
- 2008-06-13 AU AU2008261527A patent/AU2008261527C1/en not_active Ceased
- 2008-06-13 ES ES08772802.8T patent/ES2624776T3/es active Active
- 2008-06-13 WO PCT/CA2008/001139 patent/WO2008151440A1/en not_active Ceased
- 2008-06-13 EP EP08772802.8A patent/EP2155880B1/en active Active
- 2008-06-13 JP JP2010511461A patent/JP5783720B2/ja not_active Expired - Fee Related
- 2008-06-13 KR KR1020107000811A patent/KR101385050B1/ko not_active Expired - Fee Related
- 2008-06-13 BR BRPI0812538-4A patent/BRPI0812538B1/pt not_active IP Right Cessation
- 2008-06-13 MX MX2009013665A patent/MX2009013665A/es active IP Right Grant
- 2008-06-13 KR KR1020137014893A patent/KR20130075787A/ko not_active Ceased
- 2008-06-13 SG SG2012066486A patent/SG185249A1/en unknown
- 2008-06-13 PL PL08772802T patent/PL2155880T3/pl unknown
- 2008-06-13 HU HUE08772802A patent/HUE031698T2/en unknown
- 2008-06-13 CN CN2013101091944A patent/CN103382487A/zh active Pending
- 2008-06-13 CA CA2700180A patent/CA2700180C/en active Active
- 2008-06-13 DK DK08772802.8T patent/DK2155880T3/en active
- 2008-06-13 CA CA2795379A patent/CA2795379A1/en not_active Abandoned
- 2008-06-13 PT PT87728028T patent/PT2155880T/pt unknown
- 2008-06-13 NZ NZ598417A patent/NZ598417A/xx not_active IP Right Cessation
- 2008-06-13 US US12/664,567 patent/US20110008837A1/en not_active Abandoned
- 2008-06-13 NZ NZ581944A patent/NZ581944A/en unknown
- 2008-06-13 CN CN201510364867.XA patent/CN104962579A/zh active Pending
- 2008-06-13 CN CN2008801031743A patent/CN101918559A/zh active Pending
- 2008-06-13 SI SI200831699A patent/SI2155880T1/sl unknown
-
2009
- 2009-12-07 IL IL202568A patent/IL202568A/en active IP Right Grant
- 2009-12-10 TN TNP2009000512A patent/TN2009000512A1/fr unknown
- 2009-12-14 EG EG2009121826A patent/EG26600A/en active
-
2010
- 2010-01-12 ZA ZA2010/00207A patent/ZA201000207B/en unknown
- 2010-01-12 MA MA32504A patent/MA31516B1/fr unknown
-
2013
- 2013-08-08 RU RU2013137208/10A patent/RU2013137208A/ru not_active Application Discontinuation
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