RU2499053C2 - Способ синтеза белка с модифицированным профилем n-гликозилирования в растениях - Google Patents

Способ синтеза белка с модифицированным профилем n-гликозилирования в растениях Download PDF

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RU2499053C2
RU2499053C2 RU2010101024/10A RU2010101024A RU2499053C2 RU 2499053 C2 RU2499053 C2 RU 2499053C2 RU 2010101024/10 A RU2010101024/10 A RU 2010101024/10A RU 2010101024 A RU2010101024 A RU 2010101024A RU 2499053 C2 RU2499053 C2 RU 2499053C2
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plant
nucleotide sequence
target protein
protein
galt
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RU2010101024/10A
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Russian (ru)
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RU2010101024A (ru
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Марк-Андре Д'Ау
Эстелль МАРКЕ-БЛУИН
Мюриель БАРДОР
Кароль БУРЕЛЬ
Луа ФЭЙ
Патрис ЛЕРУЖ
Луи-Филипп Везина
Вероник ГОМОР
Стефани АКИН
Кристоф РИУЭЙ
Тома ПАККАЛЕ
Кристоф СУРРУЙЕ
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Медикаго Инк.
Сентр Насьональ Де Ля Решерш Сьентифик
Университе Де Руэн
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
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    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
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    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
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    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
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    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cultivation Of Plants (AREA)
RU2010101024/10A 2007-06-15 2008-06-13 Способ синтеза белка с модифицированным профилем n-гликозилирования в растениях RU2499053C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94434407P 2007-06-15 2007-06-15
US60/944,344 2007-06-15
PCT/CA2008/001139 WO2008151440A1 (en) 2007-06-15 2008-06-13 Modifying glycoprotein production in plants

Related Child Applications (1)

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RU2013137208/10A Division RU2013137208A (ru) 2007-06-15 2013-08-08 Способ синтеза белка с модифицированным профилем n-гликозилирования в растениях

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RU2010101024A RU2010101024A (ru) 2011-07-20
RU2499053C2 true RU2499053C2 (ru) 2013-11-20

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RU2010101024/10A RU2499053C2 (ru) 2007-06-15 2008-06-13 Способ синтеза белка с модифицированным профилем n-гликозилирования в растениях
RU2013137208/10A RU2013137208A (ru) 2007-06-15 2013-08-08 Способ синтеза белка с модифицированным профилем n-гликозилирования в растениях

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US (1) US20110008837A1 (enExample)
EP (1) EP2155880B1 (enExample)
JP (1) JP5783720B2 (enExample)
KR (2) KR101385050B1 (enExample)
CN (3) CN104962579A (enExample)
AU (1) AU2008261527C1 (enExample)
BR (1) BRPI0812538B1 (enExample)
CA (2) CA2700180C (enExample)
DK (1) DK2155880T3 (enExample)
EG (1) EG26600A (enExample)
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IL (1) IL202568A (enExample)
MA (1) MA31516B1 (enExample)
MX (1) MX2009013665A (enExample)
NZ (2) NZ581944A (enExample)
PL (1) PL2155880T3 (enExample)
PT (1) PT2155880T (enExample)
RU (2) RU2499053C2 (enExample)
SG (1) SG185249A1 (enExample)
SI (1) SI2155880T1 (enExample)
TN (1) TN2009000512A1 (enExample)
WO (1) WO2008151440A1 (enExample)
ZA (1) ZA201000207B (enExample)

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SI2445928T1 (en) 2009-06-24 2018-05-31 Medicago Inc. HYPER PARTICULARS, SIMILAR VIRUSES OF GRIPE, WHICH HAVE EXPOSED HEMAGLUTININE
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TWI700368B (zh) 2011-09-30 2020-08-01 苜蓿股份有限公司 增加植物類病毒顆粒產率
WO2013169009A1 (ko) * 2012-05-08 2013-11-14 경상대학교 산학협력단 고-만노오스형 n-글라이칸을 생산하는 식물체 및 이를 이용한 고-만노오스형 n-글라이칸의 생산방법
JP2016516415A (ja) 2013-03-28 2016-06-09 メディカゴ インコーポレイテッド 植物におけるインフルエンザウイルス様粒子の生成
US12467058B2 (en) 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
WO2016004536A1 (en) 2014-07-11 2016-01-14 Medicago Inc. Modifying protein production in plants
EA038931B9 (ru) * 2014-11-20 2022-02-18 Йиссум Рисерч Дивелопмент Компани Оф Зе Хебрю Юниверсити Оф Иерусалим Лтд. Композиции и способы получения полипептидов с модифицированным профилем гликозилирования в клетках растений
CA3045173A1 (en) 2016-12-01 2018-06-07 Plantform Corporation Transgenic plant with reduced fucosyltransferase and xylosyltransferase activity
BR112020004764A2 (pt) * 2017-09-11 2020-09-24 R.J. Reynolds Tobacco Company métodos e composições para aumentar a expressão de genes de interesse em uma planta por coexpressão com p21
JP7566045B2 (ja) * 2021-01-15 2024-10-11 デンカ株式会社 栽培条件を決定する方法、及び目的タンパク質又は目的ペプチドの製造方法

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RU2004106559A (ru) * 2001-08-03 2005-05-10 Гликарт Биотекнолоджи АГ (CH) Гликозилированные антитела (варианты), обладающие повышенной антителозависимой клеточной цитотоксичностью
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RU2004106559A (ru) * 2001-08-03 2005-05-10 Гликарт Биотекнолоджи АГ (CH) Гликозилированные антитела (варианты), обладающие повышенной антителозависимой клеточной цитотоксичностью
WO2003078637A2 (en) * 2002-03-19 2003-09-25 Plant Research International B.V. Optimizing glycan processing in plants
WO2004065540A2 (en) * 2003-01-22 2004-08-05 Glycart Biotechnology Ag Fusion constructs and use of same to produce antibodies with increased fc receptor binding affinity and effector function

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CN104962579A (zh) 2015-10-07
ES2624776T3 (es) 2017-07-17
BRPI0812538B1 (pt) 2021-03-16
EP2155880A4 (en) 2010-08-04
ZA201000207B (en) 2013-09-25
SI2155880T1 (sl) 2017-03-31
NZ598417A (en) 2013-06-28
WO2008151440A1 (en) 2008-12-18
MA31516B1 (fr) 2010-07-01
TN2009000512A1 (en) 2011-03-31
AU2008261527C1 (en) 2014-09-04
CN103382487A (zh) 2013-11-06
EP2155880B1 (en) 2016-08-10
HUE031698T2 (en) 2017-07-28
SG185249A1 (en) 2012-11-29
IL202568A (en) 2015-02-26
EP2155880A1 (en) 2010-02-24
WO2008151440A4 (en) 2009-02-26
WO2008151440A8 (en) 2010-03-04
PT2155880T (pt) 2016-11-18
AU2008261527A8 (en) 2010-01-21
CA2700180A1 (en) 2008-12-18
KR101385050B1 (ko) 2014-05-13
PL2155880T3 (pl) 2017-06-30
CA2795379A1 (en) 2008-12-18
MX2009013665A (es) 2010-06-02
NZ581944A (en) 2012-03-30
AU2008261527A1 (en) 2008-12-18
AU2008261527B2 (en) 2014-04-10
BRPI0812538A2 (pt) 2014-09-30
CA2700180C (en) 2013-01-29
JP5783720B2 (ja) 2015-09-24
AU2008261527B8 (en) 2014-04-24
IL202568A0 (en) 2011-08-01
RU2010101024A (ru) 2011-07-20
DK2155880T3 (en) 2016-12-05
KR20130075787A (ko) 2013-07-05
EG26600A (en) 2014-03-23
JP2010531136A (ja) 2010-09-24
US20110008837A1 (en) 2011-01-13
RU2013137208A (ru) 2015-02-20
KR20100037602A (ko) 2010-04-09
CN101918559A (zh) 2010-12-15

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