TN2009000512A1 - Modifying glycoprotein production in plants - Google Patents
Modifying glycoprotein production in plantsInfo
- Publication number
- TN2009000512A1 TN2009000512A1 TNP2009000512A TN2009000512A TN2009000512A1 TN 2009000512 A1 TN2009000512 A1 TN 2009000512A1 TN P2009000512 A TNP2009000512 A TN P2009000512A TN 2009000512 A TN2009000512 A TN 2009000512A TN 2009000512 A1 TN2009000512 A1 TN 2009000512A1
- Authority
- TN
- Tunisia
- Prior art keywords
- plant
- nucleotide sequence
- protein
- interest
- plants
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 239000002773 nucleotide Substances 0.000 abstract 5
- 125000003729 nucleotide group Chemical group 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 230000004988 N-glycosylation Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 102100023315 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase Human genes 0.000 abstract 1
- 108010056664 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 230000005021 gait Effects 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Cultivation Of Plants (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94434407P | 2007-06-15 | 2007-06-15 | |
| PCT/CA2008/001139 WO2008151440A1 (en) | 2007-06-15 | 2008-06-13 | Modifying glycoprotein production in plants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2009000512A1 true TN2009000512A1 (en) | 2011-03-31 |
Family
ID=40129187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2009000512A TN2009000512A1 (en) | 2007-06-15 | 2009-12-10 | Modifying glycoprotein production in plants |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20110008837A1 (enExample) |
| EP (1) | EP2155880B1 (enExample) |
| JP (1) | JP5783720B2 (enExample) |
| KR (2) | KR20130075787A (enExample) |
| CN (3) | CN101918559A (enExample) |
| AU (1) | AU2008261527C1 (enExample) |
| BR (1) | BRPI0812538B1 (enExample) |
| CA (2) | CA2795379A1 (enExample) |
| DK (1) | DK2155880T3 (enExample) |
| EG (1) | EG26600A (enExample) |
| ES (1) | ES2624776T3 (enExample) |
| HU (1) | HUE031698T2 (enExample) |
| IL (1) | IL202568A (enExample) |
| MA (1) | MA31516B1 (enExample) |
| MX (1) | MX2009013665A (enExample) |
| NZ (2) | NZ598417A (enExample) |
| PL (1) | PL2155880T3 (enExample) |
| PT (1) | PT2155880T (enExample) |
| RU (2) | RU2499053C2 (enExample) |
| SG (1) | SG185249A1 (enExample) |
| SI (1) | SI2155880T1 (enExample) |
| TN (1) | TN2009000512A1 (enExample) |
| WO (1) | WO2008151440A1 (enExample) |
| ZA (1) | ZA201000207B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| EP2238253B1 (en) | 2007-11-27 | 2012-09-12 | Medicago Inc. | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| CA2730171C (en) | 2008-07-08 | 2016-10-11 | Medicago Inc. | Soluble recombinant influenza antigens |
| ES2593277T3 (es) | 2008-07-18 | 2016-12-07 | Medicago Inc. | Nuevo epítopo de inmunización contra el virus de la influenza |
| NZ597401A (en) | 2009-06-24 | 2013-09-27 | Medicago Inc | Chimeric influenza virus-like particles comprising hemagglutinin |
| DK2480560T3 (en) | 2009-09-22 | 2018-04-16 | Medicago Inc | PROCEDURE FOR THE PREPARATION OF PLANT DERIVATIVE PROTEINS |
| TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
| CA2839932C (en) * | 2011-06-07 | 2022-07-05 | Ibio, Inc. | In vivo de-glycosylation of recombinant proteins by co-expression with pngase f |
| EP2551348B1 (en) | 2011-07-29 | 2014-09-24 | Icon Genetics GmbH | Production of galactosylated N-glycans in plants |
| CN116218900A (zh) | 2011-09-30 | 2023-06-06 | 麦迪卡格公司 | 增加植物中病毒样颗粒的产率 |
| WO2013169009A1 (ko) * | 2012-05-08 | 2013-11-14 | 경상대학교 산학협력단 | 고-만노오스형 n-글라이칸을 생산하는 식물체 및 이를 이용한 고-만노오스형 n-글라이칸의 생산방법 |
| ES2803508T3 (es) | 2013-03-28 | 2021-01-27 | Medicago Inc | Producción de partículas similares al virus de la gripe en plantas |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| US11959088B2 (en) | 2014-07-11 | 2024-04-16 | Aramis Biotechnologies Inc. | Modifying protein production in plants |
| CN107810271B (zh) * | 2014-11-20 | 2021-09-28 | 耶路撒冷希伯来大学伊萨姆研发公司 | 用于在植物细胞中生产具有改变的糖基化模式的多肽的组合物和方法 |
| US11499160B2 (en) | 2016-12-01 | 2022-11-15 | Plantform Corporation | Transgenic plant with reduced fucosyltransferase and xylosyltransferase activity |
| US11649465B2 (en) * | 2017-09-11 | 2023-05-16 | R.J. Reynolds Tobacco Company | Methods and compositions for increasing expression of genes of interest in a plant by co-expression with p21 |
| EP4265104A4 (en) * | 2021-01-15 | 2024-12-11 | Denka Company Limited | METHOD FOR DETERMINING CULTURE CONDITIONS, AND METHOD FOR PRODUCING DESIRED PROTEIN OR DESIRED PEPTIDE |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312746A (en) * | 1993-01-08 | 1994-05-17 | Life Technologies, Inc. | Cloning and expressing restriction endonucleases and modification methylases from caryophanon |
| GB9524350D0 (en) * | 1995-11-29 | 1996-01-31 | Lynxvale Ltd | Enhancer-increased gene expression in plants |
| US5945326A (en) * | 1997-03-20 | 1999-08-31 | New England Biolabs, Inc. | Method for cloning and producing the Spel restriction endonuclease |
| US20030175884A1 (en) * | 2001-08-03 | 2003-09-18 | Pablo Umana | Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity |
| DK1137789T3 (da) * | 1998-12-09 | 2010-11-08 | Phyton Holdings Llc | Fremgangsmåde til fremstilling af et glycoprotein med glycosylering af human type |
| MXPA02003455A (es) * | 1999-10-04 | 2002-10-23 | Medicago Inc | Promotor para regular la expresion de genes foraneos. |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| CA2388432A1 (en) * | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
| AU1738301A (en) * | 1999-10-26 | 2001-05-08 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Gonadotrophins in plants |
| DK1772518T3 (da) * | 1999-10-26 | 2010-11-22 | Stichting Dienst Landbouwkundi | Pattedyrsagtig glykosylering i planter |
| US20040214273A1 (en) * | 2001-01-19 | 2004-10-28 | Kazuhito Fujiyama | Method for secretory production of glycoprotein having human-type sugar chain using plant cell |
| US20030035774A1 (en) | 2001-07-18 | 2003-02-20 | Adjei Akwete L. | Salt/ion pair medicinal aerosol formulation |
| ES2563402T3 (es) * | 2002-02-13 | 2016-03-15 | Wisconsin Alumni Research Foundation | Señal para el empaquetamiento de vectores del virus de la gripe |
| KR101060361B1 (ko) * | 2002-03-19 | 2011-08-29 | 스티칭 디엔스트 랜드보위쿤디그 온데조에크 | 식물에서 글리칸 프로세싱의 최적화 |
| WO2003078614A2 (en) * | 2002-03-19 | 2003-09-25 | Plant Research International B.V. | Gntiii (udp-n-acethylglucosamine:beta-d mannoside beta (1,4)-n-acethylglucosaminy ltransferase iii) expression in plants |
| CN1761746B (zh) * | 2003-01-22 | 2016-03-23 | 罗氏格黎卡特股份公司 | 融合构建体及其用来生产Fc受体结合亲和性和效应子功能提高的抗体的用途 |
| PL222220B1 (pl) | 2003-01-22 | 2016-07-29 | Glycart Biotechnology Ag | Komórka gospodarza i sposób wytwarzania polipeptydu w komórce gospodarza |
| WO2004098533A2 (en) * | 2003-05-05 | 2004-11-18 | Boyce Thompson Institute For Plant Research | Vectors and cells for preparing immunoprotective compositions derived from transgenic plants |
| JP2006212019A (ja) * | 2004-04-30 | 2006-08-17 | National Institute Of Agrobiological Sciences | 植物を用いたユビキノン−１０の製造方法 |
-
2008
- 2008-06-13 MX MX2009013665A patent/MX2009013665A/es active IP Right Grant
- 2008-06-13 CN CN2008801031743A patent/CN101918559A/zh active Pending
- 2008-06-13 SI SI200831699A patent/SI2155880T1/sl unknown
- 2008-06-13 CN CN201510364867.XA patent/CN104962579A/zh active Pending
- 2008-06-13 WO PCT/CA2008/001139 patent/WO2008151440A1/en not_active Ceased
- 2008-06-13 HU HUE08772802A patent/HUE031698T2/en unknown
- 2008-06-13 EP EP08772802.8A patent/EP2155880B1/en active Active
- 2008-06-13 AU AU2008261527A patent/AU2008261527C1/en not_active Ceased
- 2008-06-13 NZ NZ598417A patent/NZ598417A/xx not_active IP Right Cessation
- 2008-06-13 BR BRPI0812538-4A patent/BRPI0812538B1/pt not_active IP Right Cessation
- 2008-06-13 SG SG2012066486A patent/SG185249A1/en unknown
- 2008-06-13 JP JP2010511461A patent/JP5783720B2/ja not_active Expired - Fee Related
- 2008-06-13 US US12/664,567 patent/US20110008837A1/en not_active Abandoned
- 2008-06-13 RU RU2010101024/10A patent/RU2499053C2/ru active
- 2008-06-13 ES ES08772802.8T patent/ES2624776T3/es active Active
- 2008-06-13 CA CA2795379A patent/CA2795379A1/en not_active Abandoned
- 2008-06-13 DK DK08772802.8T patent/DK2155880T3/en active
- 2008-06-13 PT PT87728028T patent/PT2155880T/pt unknown
- 2008-06-13 NZ NZ581944A patent/NZ581944A/en unknown
- 2008-06-13 CN CN2013101091944A patent/CN103382487A/zh active Pending
- 2008-06-13 CA CA2700180A patent/CA2700180C/en active Active
- 2008-06-13 KR KR1020137014893A patent/KR20130075787A/ko not_active Ceased
- 2008-06-13 KR KR1020107000811A patent/KR101385050B1/ko not_active Expired - Fee Related
- 2008-06-13 PL PL08772802T patent/PL2155880T3/pl unknown
-
2009
- 2009-12-07 IL IL202568A patent/IL202568A/en active IP Right Grant
- 2009-12-10 TN TNP2009000512A patent/TN2009000512A1/fr unknown
- 2009-12-14 EG EG2009121826A patent/EG26600A/en active
-
2010
- 2010-01-12 ZA ZA2010/00207A patent/ZA201000207B/en unknown
- 2010-01-12 MA MA32504A patent/MA31516B1/fr unknown
-
2013
- 2013-08-08 RU RU2013137208/10A patent/RU2013137208A/ru not_active Application Discontinuation
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