JP2010529969A5 - - Google Patents
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- Publication number
- JP2010529969A5 JP2010529969A5 JP2010511510A JP2010511510A JP2010529969A5 JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5 JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5
- Authority
- JP
- Japan
- Prior art keywords
- ethylamino
- alkyl
- butoxyphenyl
- compound
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07011766 | 2007-06-15 | ||
| EP07011766.8 | 2007-06-15 | ||
| PCT/EP2008/003848 WO2008151702A1 (en) | 2007-06-15 | 2008-05-14 | Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010529969A JP2010529969A (ja) | 2010-09-02 |
| JP2010529969A5 true JP2010529969A5 (https=) | 2012-06-07 |
| JP5440496B2 JP5440496B2 (ja) | 2014-03-12 |
Family
ID=38658156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010511510A Active JP5440496B2 (ja) | 2007-06-15 | 2008-05-14 | 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用 |
Country Status (27)
| Country | Link |
|---|---|
| US (8) | US8519000B2 (https=) |
| EP (1) | EP2155663B1 (https=) |
| JP (1) | JP5440496B2 (https=) |
| KR (1) | KR101545124B1 (https=) |
| CN (1) | CN101687773B (https=) |
| AR (1) | AR068976A1 (https=) |
| AU (1) | AU2008261325B2 (https=) |
| BR (1) | BRPI0813363B8 (https=) |
| CA (1) | CA2689561C (https=) |
| CY (1) | CY1119787T1 (https=) |
| DK (1) | DK2155663T3 (https=) |
| EA (1) | EA018195B1 (https=) |
| ES (1) | ES2655704T3 (https=) |
| HR (1) | HRP20180324T8 (https=) |
| HU (1) | HUE038113T2 (https=) |
| IL (1) | IL202235A (https=) |
| LT (1) | LT2155663T (https=) |
| MX (1) | MX2009013119A (https=) |
| NO (1) | NO2155663T3 (https=) |
| NZ (1) | NZ581288A (https=) |
| PL (1) | PL2155663T3 (https=) |
| PT (1) | PT2155663T (https=) |
| RS (1) | RS56780B1 (https=) |
| SI (1) | SI2155663T1 (https=) |
| TR (1) | TR201802576T4 (https=) |
| TW (1) | TWI400071B (https=) |
| WO (1) | WO2008151702A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004266494B2 (en) * | 2003-08-25 | 2010-04-08 | Newron Pharmaceuticals, Spa | Alpha-aminoamide derivatives useful as anti-inflammatory agents |
| JP5213265B2 (ja) * | 2009-10-08 | 2013-06-19 | 花王株式会社 | Ｌｏｘ−１発現調節剤の評価又は選択方法 |
| ES2602140T3 (es) * | 2011-06-27 | 2017-02-17 | Newron Pharmaceuticals S.P.A. | Derivados de arilalquilaminocarboxamida fluorados |
| CN103804341B (zh) * | 2012-11-13 | 2018-04-10 | 中国人民解放军军事医学科学院毒物药物研究所 | 酰胺衍生物及其医药用途 |
| CN104761531B (zh) * | 2014-01-03 | 2017-12-01 | 中国人民解放军军事医学科学院毒物药物研究所 | 镇痛活性化合物及其医药用途 |
| WO2017083867A1 (en) * | 2015-11-12 | 2017-05-18 | Afasci, Inc. | Ion channel inhibitory compounds, pharmaceutical formulations and uses |
| CN106316824B (zh) * | 2016-08-18 | 2018-10-19 | 广州康瑞泰药业有限公司 | 一种合成2-氟环丙烷甲酸的新方法 |
| CN112041296B (zh) * | 2018-04-28 | 2023-12-29 | 上海璃道医药科技有限公司 | 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途 |
| CN112714670A (zh) * | 2018-08-30 | 2021-04-27 | 沙特基础工业全球技术公司 | 具有改良异构化的芳构化催化剂、其制造和使用方法 |
| EP3725769A1 (en) | 2019-04-17 | 2020-10-21 | Newron Pharmaceuticals S.p.A. | Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives |
| EP3725768A1 (en) * | 2019-04-17 | 2020-10-21 | Newron Pharmaceuticals S.p.A. | Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives |
| MA72559B1 (fr) | 2023-04-28 | 2026-02-27 | Newron Pharmaceuticals S.P.A. | Formes cristallines d'homonamide |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB586645A (en) * | 1944-07-19 | 1947-03-26 | Burroughs Wellcome Co | Improvements relating to the synthesis of amino acid derivatives and salts thereof |
| GB1254332A (en) * | 1969-02-27 | 1971-11-17 | Science Union & Cie | Amino acids and their derivatives and processes for preparing them |
| IL94466A (en) * | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
| US5051403A (en) | 1989-11-22 | 1991-09-24 | Neurex Corporation | Method of treating ischemia-related neuronal damage |
| SG50624A1 (en) | 1991-12-30 | 1998-07-20 | Neurex Corp | Methods of producing analgesia and enhancing opiate analgesia |
| GB9500691D0 (en) | 1995-01-13 | 1995-03-08 | Smithkline Beecham Plc | Compounds |
| GB9515412D0 (en) | 1995-07-27 | 1995-09-27 | Pharmacia Spa | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives |
| GB9518572D0 (en) | 1995-09-12 | 1995-11-15 | Smithkline Beecham Plc | Compounds |
| US5845454A (en) * | 1996-04-23 | 1998-12-08 | Malizia; John T. | Drop ceiling hanging system |
| EP0910565A1 (en) | 1997-02-14 | 1999-04-28 | Bayer Corporation | Amide derivatives as selective neuropeptide y receptor antagonists |
| US6117841A (en) | 1997-05-30 | 2000-09-12 | Warner-Lambert Company | Substituted peptidylamine calcium channel blockers |
| DE19740110A1 (de) | 1997-09-12 | 1999-03-18 | Boehringer Ingelheim Pharma | Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| GB9727523D0 (en) * | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| US6458781B1 (en) | 1998-04-27 | 2002-10-01 | David Thomas Connor | Substituted diarylalkyl amides as calcium channel antagonists |
| US6011035A (en) | 1998-06-30 | 2000-01-04 | Neuromed Technologies Inc. | Calcium channel blockers |
| WO2000006559A1 (en) | 1998-07-30 | 2000-02-10 | Warner-Lambert Company | Reduced dipeptide analogues as calcium channel antagonists |
| US6472530B1 (en) | 1999-09-22 | 2002-10-29 | Ortho-Mcneil Pharmaceutical, Inc. | Benzo-fused dithiepino[6,5-b]pyridines, and related compositions and methods |
| JP2003528104A (ja) | 2000-03-23 | 2003-09-24 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | チエピノ［３，２−ｂ］ジヒドロピリジンおよび関連組成物ならびに方法 |
| WO2001074779A1 (en) | 2000-03-31 | 2001-10-11 | Euro-Celtique S.A. | Aminopyridines and their use as anticonvulsants and sodium channel blockers |
| US6521647B2 (en) | 2000-04-04 | 2003-02-18 | Pfizer Inc. | Treatment of renal disorders |
| SE0102858D0 (sv) | 2001-08-27 | 2001-08-27 | Astrazeneca Ab | N-type calcium channel antagonists for the treatment of pain |
| IL160523A0 (en) | 2001-09-03 | 2004-07-25 | Newron Pharm Spa | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN alpha-AMINOAMIDE AND ITS ANALGESIC USE |
| EP1458386B1 (en) | 2001-12-27 | 2007-04-18 | Ortho-McNeil Pharmaceutical, Inc. | Aroyl pyrrole heteroeryl and methanols useful for treating a central nervous system disorder |
| EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
| WO2004087125A1 (en) * | 2003-04-02 | 2004-10-14 | Ionix Pharmaceuticals Limited | Amino acid derivatives as inhibitors of mammalian sodium channels |
| AR044007A1 (es) | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
| AU2004266494B2 (en) * | 2003-08-25 | 2010-04-08 | Newron Pharmaceuticals, Spa | Alpha-aminoamide derivatives useful as anti-inflammatory agents |
| EP1557166A1 (en) * | 2004-01-21 | 2005-07-27 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders |
| EP1588704A1 (en) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
| ATE471147T1 (de) | 2004-09-10 | 2010-07-15 | Newron Pharm Spa | Verwendung von (r)-(halogenbenzyloxy)-benzylamino-propanamiden als natrium- und/oder calciumkanal- selektive modulatoren |
| EP1963280B1 (en) * | 2005-12-22 | 2015-10-28 | Newron Pharmaceuticals S.p.A. | 2-phenylethylamino derivatives as calcium and/or sodium channel modulators |
| EP1870097A1 (en) | 2006-06-15 | 2007-12-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of cognitive disorders |
-
2008
- 2008-05-14 PT PT87494498T patent/PT2155663T/pt unknown
- 2008-05-14 WO PCT/EP2008/003848 patent/WO2008151702A1/en not_active Ceased
- 2008-05-14 ES ES08749449.8T patent/ES2655704T3/es active Active
- 2008-05-14 LT LTEP08749449.8T patent/LT2155663T/lt unknown
- 2008-05-14 PL PL08749449T patent/PL2155663T3/pl unknown
- 2008-05-14 HR HRP20180324TT patent/HRP20180324T8/hr unknown
- 2008-05-14 EP EP08749449.8A patent/EP2155663B1/en active Active
- 2008-05-14 US US12/663,926 patent/US8519000B2/en active Active
- 2008-05-14 RS RS20180061A patent/RS56780B1/sr unknown
- 2008-05-14 NZ NZ581288A patent/NZ581288A/en unknown
- 2008-05-14 AU AU2008261325A patent/AU2008261325B2/en active Active
- 2008-05-14 KR KR1020107001038A patent/KR101545124B1/ko active Active
- 2008-05-14 MX MX2009013119A patent/MX2009013119A/es active IP Right Grant
- 2008-05-14 DK DK08749449.8T patent/DK2155663T3/en active
- 2008-05-14 NO NO08749449A patent/NO2155663T3/no unknown
- 2008-05-14 HU HUE08749449A patent/HUE038113T2/hu unknown
- 2008-05-14 JP JP2010511510A patent/JP5440496B2/ja active Active
- 2008-05-14 EA EA201070018A patent/EA018195B1/ru unknown
- 2008-05-14 SI SI200831914T patent/SI2155663T1/en unknown
- 2008-05-14 CA CA2689561A patent/CA2689561C/en active Active
- 2008-05-14 BR BRPI0813363A patent/BRPI0813363B8/pt active IP Right Grant
- 2008-05-14 TR TR2018/02576T patent/TR201802576T4/tr unknown
- 2008-05-14 CN CN200880020386.5A patent/CN101687773B/zh active Active
- 2008-05-19 TW TW097118361A patent/TWI400071B/zh active
- 2008-06-13 AR ARP080102533A patent/AR068976A1/es active IP Right Grant
-
2009
- 2009-11-19 IL IL202235A patent/IL202235A/en active IP Right Grant
-
2013
- 2013-03-11 US US13/794,555 patent/US9051240B2/en active Active
- 2013-03-11 US US13/794,377 patent/US9248116B2/en active Active
-
2015
- 2015-02-05 US US14/615,227 patent/US9474739B2/en active Active
- 2015-02-05 US US14/614,758 patent/US9474737B2/en active Active
- 2015-02-05 US US14/615,176 patent/US9474738B2/en active Active
- 2015-02-05 US US14/615,275 patent/US9603832B2/en active Active
- 2015-02-05 US US14/614,677 patent/US9585869B2/en active Active
-
2018
- 2018-01-16 CY CY20181100053T patent/CY1119787T1/el unknown
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