SI1458386T1 - Aroil pirol heteroeril in metanoli, uporabni za zdravljenje motnje centralnega živčnega sistema - Google Patents

Aroil pirol heteroeril in metanoli, uporabni za zdravljenje motnje centralnega živčnega sistema

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Publication number
SI1458386T1
SI1458386T1 SI200230550T SI200230550T SI1458386T1 SI 1458386 T1 SI1458386 T1 SI 1458386T1 SI 200230550 T SI200230550 T SI 200230550T SI 200230550 T SI200230550 T SI 200230550T SI 1458386 T1 SI1458386 T1 SI 1458386T1
Authority
SI
Slovenia
Prior art keywords
heteroeryl
methanols
treating
useful
nervous system
Prior art date
Application number
SI200230550T
Other languages
English (en)
Inventor
John R Carson
Ellen E Codd
Philip M Pitis
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of SI1458386T1 publication Critical patent/SI1458386T1/sl

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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
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    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P9/00Drugs for disorders of the cardiovascular system
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    • A61P9/00Drugs for disorders of the cardiovascular system
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    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
SI200230550T 2001-12-27 2002-12-10 Aroil pirol heteroeril in metanoli, uporabni za zdravljenje motnje centralnega živčnega sistema SI1458386T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34376801P 2001-12-27 2001-12-27
PCT/US2002/039487 WO2003057219A1 (en) 2001-12-27 2002-12-10 Aroyl pyrrole heteroeryl and methanols useful for treating a central nervous system disorder
EP02799923A EP1458386B1 (en) 2001-12-27 2002-12-10 Aroyl pyrrole heteroeryl and methanols useful for treating a central nervous system disorder

Publications (1)

Publication Number Publication Date
SI1458386T1 true SI1458386T1 (sl) 2007-08-31

Family

ID=23347573

Family Applications (1)

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SI200230550T SI1458386T1 (sl) 2001-12-27 2002-12-10 Aroil pirol heteroeril in metanoli, uporabni za zdravljenje motnje centralnega živčnega sistema

Country Status (14)

Country Link
US (3) US6897319B2 (sl)
EP (1) EP1458386B1 (sl)
JP (1) JP2005514412A (sl)
AR (1) AR038664A1 (sl)
AT (1) ATE359783T1 (sl)
AU (2) AU2002364545A1 (sl)
CY (1) CY1106658T1 (sl)
DE (1) DE60219687T2 (sl)
DK (1) DK1458386T3 (sl)
ES (1) ES2286328T3 (sl)
PT (1) PT1458386E (sl)
SI (1) SI1458386T1 (sl)
TW (1) TWI282277B (sl)
WO (2) WO2003057219A1 (sl)

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* Cited by examiner, † Cited by third party
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DE602004025586D1 (de) * 2003-08-25 2010-04-01 Newron Pharm Spa Alpha-aminoamid derivate zur verwendung als anti-inflammatorische wirkstoffe
EP1533298A1 (en) * 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. 3-aminopyrrolidone derivatives
EP1533295A1 (en) * 2003-11-24 2005-05-25 Newron Pharmaceuticals S.p.A. Cyclopentyl Derivatives
CN100371325C (zh) * 2004-07-23 2008-02-27 中国科学院上海药物研究所 一类茚并吲哚酮类化合物、其制备方法和用途
ES2347581T3 (es) * 2004-09-10 2010-11-02 Newron Pharmaceuticals S.P.A. Uso de (r)-(halobenciloxi)bencilamino-propanamidas como moduladores selectivos del canal de sodio y/o calcio.
US7598380B2 (en) * 2005-08-03 2009-10-06 Bristol-Myers Squibb Company Method of preparation of azaindole derivatives
AU2006329040C1 (en) 2005-12-22 2011-12-08 Newron Pharmaceuticals S.P.A. 2 -Phenylethylamino derivatives as calcium and/or sodium channel modulators
CN101687773B (zh) 2007-06-15 2014-07-30 纽朗制药有限公司 取代的2-[2-(苯基)乙氨基]烷酰胺衍生物及其作为钠和/或钙通道调节剂的应用
GB0804755D0 (en) * 2008-03-14 2008-04-16 Angeletti P Ist Richerche Bio Therapeutic compounds
GB0813873D0 (en) * 2008-07-30 2008-09-03 Univ Dundee Compounds
RU2559888C2 (ru) * 2009-07-10 2015-08-20 Зе Дженерал Хоспитал Корпорэйшн Аналоги этомидата, которые не ингибируют синтез адренокортикостероидов
ME02524B (me) 2011-06-27 2017-02-20 Newron Pharm Spa Fluorisani derivati arilalkilaminokarboksamida
LT2802325T (lt) 2012-01-13 2017-03-10 The General Hospital Corporation Anesteziniai junginiai ir su jais susiję panaudojimo būdai
WO2022159980A1 (en) * 2021-01-25 2022-07-28 Athos Therapeutics, Inc. Pharmaceutical compounds and methods of making and using the same

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EP0751767A4 (en) 1994-02-03 1997-12-10 Cambridge Neuroscience Inc GUANIDINE FOR THERAPEUTIC USE
GB9509156D0 (en) 1995-05-05 1995-06-28 Sandoz Ltd Organic compounds
CA2264231A1 (en) 1996-08-29 1998-03-05 Takeda Chemical Industries, Ltd. Cyclic ether compounds as sodium channel modulators
MA26473A1 (fr) 1997-03-01 2004-12-20 Glaxo Group Ltd Composes pharmacologiquement actifs.
US6110937A (en) 1997-04-03 2000-08-29 Syntex Usa, Inc. Phenoxymethyl piperidine derivatives for the treatment of neuropathic pain
GB9726987D0 (en) 1997-12-22 1998-02-18 Glaxo Group Ltd Compounds
US6256307B1 (en) * 1998-03-27 2001-07-03 Hewlett-Packard Co. Local area network receive filter
WO2000002865A1 (en) 1998-07-08 2000-01-20 Monash University Pharmaceutical agents
DE19834714A1 (de) 1998-07-31 2000-02-03 Boehringer Ingelheim Pharma Neue 2,3,3a,4,9,9a-Hexahydro-8-hydroxy-1H-ben[f]indole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US6169118B1 (en) * 1998-11-12 2001-01-02 Block Drug Company, Inc. Flavor blend for masking unpleasant taste of zinc compounds
US6281211B1 (en) 1999-02-04 2001-08-28 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
WO2000048584A2 (en) * 1999-02-18 2000-08-24 Ortho-Mcneil Pharmaceutical, Inc. Aroyl aminoacyl pyrroles for use in the treatment of neuropathic pain
CA2300698C (en) 1999-02-19 2003-10-07 J. Garfield Purdon Broad spectrum decontamination formulation and method of use
DE19915602A1 (de) 1999-04-07 2000-10-19 Gruenenthal Gmbh 3-Amino-4-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung
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WO2001023571A1 (en) 1999-09-30 2001-04-05 The Regents Of The University Of Michigan Methods and compositions relating to sodium channel beta1a subunits

Also Published As

Publication number Publication date
TW200400030A (en) 2004-01-01
EP1458386A1 (en) 2004-09-22
AU2002364545A1 (en) 2003-07-24
TWI282277B (en) 2007-06-11
AU2002359856A1 (en) 2003-07-24
AU2002359856A8 (en) 2003-07-24
WO2003057147A2 (en) 2003-07-17
EP1458386B1 (en) 2007-04-18
AR038664A1 (es) 2005-01-26
ATE359783T1 (de) 2007-05-15
US20030181481A1 (en) 2003-09-25
CY1106658T1 (el) 2012-01-25
WO2003057147A3 (en) 2003-10-23
WO2003057219A1 (en) 2003-07-17
ES2286328T3 (es) 2007-12-01
US20050148636A1 (en) 2005-07-07
US6897319B2 (en) 2005-05-24
DK1458386T3 (da) 2007-08-13
DE60219687T2 (de) 2007-12-27
JP2005514412A (ja) 2005-05-19
DE60219687D1 (de) 2007-05-31
US20040058980A1 (en) 2004-03-25
PT1458386E (pt) 2007-06-04

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