JP2010529969A5 - - Google Patents
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- Publication number
- JP2010529969A5 JP2010529969A5 JP2010511510A JP2010511510A JP2010529969A5 JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5 JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010511510 A JP2010511510 A JP 2010511510A JP 2010529969 A5 JP2010529969 A5 JP 2010529969A5
- Authority
- JP
- Japan
- Prior art keywords
- ethylamino
- alkyl
- butoxyphenyl
- compound
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07011766 | 2007-06-15 | ||
| EP07011766.8 | 2007-06-15 | ||
| PCT/EP2008/003848 WO2008151702A1 (en) | 2007-06-15 | 2008-05-14 | Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010529969A JP2010529969A (ja) | 2010-09-02 |
| JP2010529969A5 true JP2010529969A5 (cg-RX-API-DMAC7.html) | 2012-06-07 |
| JP5440496B2 JP5440496B2 (ja) | 2014-03-12 |
Family
ID=38658156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010511510A Active JP5440496B2 (ja) | 2007-06-15 | 2008-05-14 | 置換２−［２−（フェニル）エチルアミノ］アルカンアミド誘導体ならびにナトリウムおよび／またはカルシウムチャネル調節剤としてのこれらの使用 |
Country Status (27)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1658062T1 (sl) * | 2003-08-25 | 2010-05-31 | Newron Pharm Spa | Alfa aminoamidni derivati uporabni kot protivnetna sredstva |
| JP5213265B2 (ja) * | 2009-10-08 | 2013-06-19 | 花王株式会社 | Ｌｏｘ−１発現調節剤の評価又は選択方法 |
| MX345873B (es) * | 2011-06-27 | 2017-02-21 | Newron Pharm Spa | Derivados de arilalquilaminocarboxamida fluorados. |
| CN103804341B (zh) * | 2012-11-13 | 2018-04-10 | 中国人民解放军军事医学科学院毒物药物研究所 | 酰胺衍生物及其医药用途 |
| CN104761531B (zh) * | 2014-01-03 | 2017-12-01 | 中国人民解放军军事医学科学院毒物药物研究所 | 镇痛活性化合物及其医药用途 |
| MX383833B (es) * | 2015-11-12 | 2025-03-14 | Afasci Inc | Compuestos inhibidores de canales ionicos, formulaciones farmaceuticas y usos. |
| CN106316824B (zh) * | 2016-08-18 | 2018-10-19 | 广州康瑞泰药业有限公司 | 一种合成2-氟环丙烷甲酸的新方法 |
| WO2019205147A1 (zh) * | 2018-04-28 | 2019-10-31 | 上海璃道医药科技有限公司 | 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途 |
| WO2020044309A1 (en) * | 2018-08-30 | 2020-03-05 | Sabic Global Technologies B.V. | Aromatization catalyst with improved isomerization, process of making and using thereof |
| EP3725768A1 (en) * | 2019-04-17 | 2020-10-21 | Newron Pharmaceuticals S.p.A. | Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives |
| EP3725769A1 (en) | 2019-04-17 | 2020-10-21 | Newron Pharmaceuticals S.p.A. | Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives |
| TW202448849A (zh) | 2023-04-28 | 2024-12-16 | 義大利商紐隆製藥公司 | 依維那胺(evenamide)之晶形 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB586645A (en) | 1944-07-19 | 1947-03-26 | Burroughs Wellcome Co | Improvements relating to the synthesis of amino acid derivatives and salts thereof |
| GB1254332A (en) | 1969-02-27 | 1971-11-17 | Science Union & Cie | Amino acids and their derivatives and processes for preparing them |
| IL94466A (en) * | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
| US5051403A (en) * | 1989-11-22 | 1991-09-24 | Neurex Corporation | Method of treating ischemia-related neuronal damage |
| WO1993013128A1 (en) * | 1991-12-30 | 1993-07-08 | Neurex Corporation | Methods of producing analgesia and enhancing opiate analgesia |
| GB9500691D0 (en) * | 1995-01-13 | 1995-03-08 | Smithkline Beecham Plc | Compounds |
| GB9515412D0 (en) | 1995-07-27 | 1995-09-27 | Pharmacia Spa | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives |
| GB9518572D0 (en) | 1995-09-12 | 1995-11-15 | Smithkline Beecham Plc | Compounds |
| US5845454A (en) * | 1996-04-23 | 1998-12-08 | Malizia; John T. | Drop ceiling hanging system |
| CA2251368A1 (en) | 1997-02-14 | 1998-08-20 | Bayer Corporation | Amide derivatives as selective neuropeptide y receptor antagonists |
| WO1998054123A1 (en) * | 1997-05-30 | 1998-12-03 | Warner-Lambert Company | Substituted peptidylamine calcium channel blockers |
| DE19740110A1 (de) | 1997-09-12 | 1999-03-18 | Boehringer Ingelheim Pharma | Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| GB9727523D0 (en) * | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| US6458781B1 (en) * | 1998-04-27 | 2002-10-01 | David Thomas Connor | Substituted diarylalkyl amides as calcium channel antagonists |
| US6011035A (en) * | 1998-06-30 | 2000-01-04 | Neuromed Technologies Inc. | Calcium channel blockers |
| AU4329499A (en) * | 1998-07-30 | 2000-02-21 | Warner-Lambert Company | Reduced dipeptide analogues as calcium channel antagonists |
| AU7102700A (en) * | 1999-09-22 | 2001-04-24 | Ortho-Mcneil Pharmaceutical, Inc. | Benzo-fused dithiepino[6,5-b]pyridines, and related compositions and methods |
| AU4732001A (en) * | 2000-03-23 | 2001-10-03 | Ortho Mcneil Pharm Inc | Thiepino (3,2-b) dihydropyridines and related compositions and methods |
| JP2003529589A (ja) | 2000-03-31 | 2003-10-07 | ユーロ−セルティック エス． ア． | アミノピリジンならびにこれらの鎮痙薬およびナトリウムチャンネル遮断薬としての使用 |
| US6521647B2 (en) * | 2000-04-04 | 2003-02-18 | Pfizer Inc. | Treatment of renal disorders |
| SE0102858D0 (sv) | 2001-08-27 | 2001-08-27 | Astrazeneca Ab | N-type calcium channel antagonists for the treatment of pain |
| ATE317280T1 (de) | 2001-09-03 | 2006-02-15 | Newron Pharm Spa | Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung |
| AU2002364545A1 (en) | 2001-12-27 | 2003-07-24 | Ortho-Mcneil Pharmaceutical Inc. | Aroyl pyrrole heteroeryl and methanols useful for treating a central nervous system disorder |
| EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
| WO2004087125A1 (en) * | 2003-04-02 | 2004-10-14 | Ionix Pharmaceuticals Limited | Amino acid derivatives as inhibitors of mammalian sodium channels |
| AR044007A1 (es) | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
| SI1658062T1 (sl) * | 2003-08-25 | 2010-05-31 | Newron Pharm Spa | Alfa aminoamidni derivati uporabni kot protivnetna sredstva |
| EP1557166A1 (en) * | 2004-01-21 | 2005-07-27 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders |
| EP1588704A1 (en) * | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
| DK1809271T5 (da) | 2004-09-10 | 2010-12-06 | Newron Pharm Spa | Anvendelse af (R)-(halogenbenzyloxy)benzylaminopropanamider som natrium- og/eller calciumkanalselektive modulatorer |
| EP1963280B1 (en) * | 2005-12-22 | 2015-10-28 | Newron Pharmaceuticals S.p.A. | 2-phenylethylamino derivatives as calcium and/or sodium channel modulators |
| EP1870097A1 (en) | 2006-06-15 | 2007-12-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of cognitive disorders |
-
2008
- 2008-05-14 EA EA201070018A patent/EA018195B1/ru unknown
- 2008-05-14 DK DK08749449.8T patent/DK2155663T3/en active
- 2008-05-14 PL PL08749449T patent/PL2155663T3/pl unknown
- 2008-05-14 US US12/663,926 patent/US8519000B2/en active Active
- 2008-05-14 KR KR1020107001038A patent/KR101545124B1/ko active Active
- 2008-05-14 CN CN200880020386.5A patent/CN101687773B/zh active Active
- 2008-05-14 ES ES08749449.8T patent/ES2655704T3/es active Active
- 2008-05-14 NZ NZ581288A patent/NZ581288A/en unknown
- 2008-05-14 EP EP08749449.8A patent/EP2155663B1/en active Active
- 2008-05-14 MX MX2009013119A patent/MX2009013119A/es active IP Right Grant
- 2008-05-14 BR BRPI0813363A patent/BRPI0813363B8/pt active IP Right Grant
- 2008-05-14 LT LTEP08749449.8T patent/LT2155663T/lt unknown
- 2008-05-14 HR HRP20180324TT patent/HRP20180324T8/hr unknown
- 2008-05-14 HU HUE08749449A patent/HUE038113T2/hu unknown
- 2008-05-14 CA CA2689561A patent/CA2689561C/en active Active
- 2008-05-14 RS RS20180061A patent/RS56780B1/sr unknown
- 2008-05-14 NO NO08749449A patent/NO2155663T3/no unknown
- 2008-05-14 AU AU2008261325A patent/AU2008261325B2/en active Active
- 2008-05-14 PT PT87494498T patent/PT2155663T/pt unknown
- 2008-05-14 TR TR2018/02576T patent/TR201802576T4/tr unknown
- 2008-05-14 WO PCT/EP2008/003848 patent/WO2008151702A1/en not_active Ceased
- 2008-05-14 JP JP2010511510A patent/JP5440496B2/ja active Active
- 2008-05-14 SI SI200831914T patent/SI2155663T1/en unknown
- 2008-05-19 TW TW097118361A patent/TWI400071B/zh active
- 2008-06-13 AR ARP080102533A patent/AR068976A1/es active IP Right Grant
-
2009
- 2009-11-19 IL IL202235A patent/IL202235A/en active IP Right Grant
-
2013
- 2013-03-11 US US13/794,555 patent/US9051240B2/en active Active
- 2013-03-11 US US13/794,377 patent/US9248116B2/en active Active
-
2015
- 2015-02-05 US US14/615,227 patent/US9474739B2/en active Active
- 2015-02-05 US US14/615,176 patent/US9474738B2/en active Active
- 2015-02-05 US US14/614,677 patent/US9585869B2/en active Active
- 2015-02-05 US US14/615,275 patent/US9603832B2/en active Active
- 2015-02-05 US US14/614,758 patent/US9474737B2/en active Active
-
2018
- 2018-01-16 CY CY20181100053T patent/CY1119787T1/el unknown
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