|
JPS59186924A
(ja)
*
|
1983-04-08 |
1984-10-23 |
Kureha Chem Ind Co Ltd |
ヒト免疫グロブリン結合抗腫瘍剤
|
|
JPS60501759A
(ja)
*
|
1983-07-01 |
1985-10-17 |
バテル メモリアル インステイチユ−ト |
生物分解性ポリペプチド及び薬剤の緩慢な放出のためのその使用
|
|
US5385738A
(en)
*
|
1983-10-14 |
1995-01-31 |
Sumitomo Pharmaceuticals Company, Ltd. |
Sustained-release injection
|
|
CS254355B1
(en)
*
|
1985-04-10 |
1988-01-15 |
Vladimir Saudek |
Soluble and biodegradatable copolymeres activated for bond of biologicaly active substances
|
|
CH667874A5
(fr)
*
|
1985-12-19 |
1988-11-15 |
Battelle Memorial Institute |
Polypeptide synthetique biodegradable et son utilisation pour la preparation de medicaments.
|
|
US6673347B1
(en)
*
|
1986-04-30 |
2004-01-06 |
Gryphon Therapeutics |
Polypeptide and protein derivatives and process for their preparation
|
|
IN165717B
(enExample)
*
|
1986-08-07 |
1989-12-23 |
Battelle Memorial Institute |
|
|
DE3806795A1
(de)
*
|
1988-02-29 |
1989-09-07 |
Schering Ag |
Polymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
|
|
JP2517760B2
(ja)
*
|
1989-05-11 |
1996-07-24 |
新技術事業団 |
水溶性高分子化医薬製剤
|
|
US5580575A
(en)
*
|
1989-12-22 |
1996-12-03 |
Imarx Pharmaceutical Corp. |
Therapeutic drug delivery systems
|
|
US6517824B1
(en)
*
|
1990-05-14 |
2003-02-11 |
University Of Medicine & Denistry Of New Jersey |
Polymer compositions comprising antifibrotic agents, and methods of treatment, pharmaceutical compositions, and methods of preparation therefor
|
|
US5372807A
(en)
*
|
1990-05-14 |
1994-12-13 |
University Of Medicine And Dentistry Of New Jersey |
Polymers containing antifibrotic agents, compositions containing such polymers, and methods of preparation and use
|
|
US5219564A
(en)
*
|
1990-07-06 |
1993-06-15 |
Enzon, Inc. |
Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
|
|
US5660822A
(en)
*
|
1990-05-14 |
1997-08-26 |
University Of Medicine & Dentistry Of N.J. |
Polymers containing antifibrotic agents, compositions containing such polymers, and methods of preparation and use
|
|
US6762188B1
(en)
*
|
1990-06-19 |
2004-07-13 |
Smithkline Beecham Corporation |
Pharmaceutically active benzoquinazoline compounds
|
|
GB9013615D0
(en)
*
|
1990-06-19 |
1990-08-08 |
Wellcome Found |
Pharmaceutical compounds
|
|
GB9120653D0
(en)
*
|
1991-09-27 |
1991-11-06 |
Procter & Gamble |
Dispensing agent
|
|
US5384333A
(en)
*
|
1992-03-17 |
1995-01-24 |
University Of Miami |
Biodegradable injectable drug delivery polymer
|
|
KR940003548U
(ko)
*
|
1992-08-14 |
1994-02-21 |
김형술 |
세탁물 건조기
|
|
US5871710A
(en)
*
|
1992-09-04 |
1999-02-16 |
The General Hospital Corporation |
Graft co-polymer adducts of platinum (II) compounds
|
|
FR2695563B1
(fr)
*
|
1992-09-11 |
1994-12-02 |
Pasteur Institut |
Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires.
|
|
CA2155947C
(en)
*
|
1993-02-22 |
2007-08-21 |
Mark W. Grinstaff |
Methods for in vivo delivery of biologics and compositions useful therefor
|
|
US6096331A
(en)
*
|
1993-02-22 |
2000-08-01 |
Vivorx Pharmaceuticals, Inc. |
Methods and compositions useful for administration of chemotherapeutic agents
|
|
US6753006B1
(en)
*
|
1993-02-22 |
2004-06-22 |
American Bioscience, Inc. |
Paclitaxel-containing formulations
|
|
US6749868B1
(en)
*
|
1993-02-22 |
2004-06-15 |
American Bioscience, Inc. |
Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
|
|
US6537579B1
(en)
*
|
1993-02-22 |
2003-03-25 |
American Bioscience, Inc. |
Compositions and methods for administration of pharmacologically active compounds
|
|
US5449720A
(en)
*
|
1993-05-24 |
1995-09-12 |
Biotech Australia Pty Limited |
Amplification of the VB12 uptake system using polymers
|
|
US5548064A
(en)
*
|
1993-05-24 |
1996-08-20 |
Biotech Australia Pty Limited |
Vitamin B12 conjugates with EPO, analogues thereof and pharmaceutical compositions
|
|
JPH09500411A
(ja)
*
|
1993-07-13 |
1997-01-14 |
アボツト・ラボラトリーズ |
蛍光性ポリマー標識された接合体および中間体
|
|
GB2282384B8
(en)
*
|
1993-08-18 |
1997-09-04 |
Europ Economic Community |
Drug delivery agents incorporating mitomycin
|
|
US6441026B1
(en)
*
|
1993-11-08 |
2002-08-27 |
Aventis Pharma S.A. |
Antitumor compositions containing taxane derivatives
|
|
US6713045B1
(en)
*
|
1995-06-02 |
2004-03-30 |
Research Corporation Technologies, Inc. |
Targeted magnetic resonance imaging agents for the detection of physiological processes
|
|
US5762909A
(en)
*
|
1995-08-31 |
1998-06-09 |
General Electric Company |
Tumor targeting with polymeric molecules having extended conformation
|
|
DE19548114C2
(de)
*
|
1995-12-21 |
2000-04-27 |
Deutsches Krebsforsch |
Konjugat, umfassend einen Wirkstoff, ein Polypeptid und einen Polyether
|
|
US6441025B2
(en)
*
|
1996-03-12 |
2002-08-27 |
Pg-Txl Company, L.P. |
Water soluble paclitaxel derivatives
|
|
PL189698B1
(pl)
*
|
1996-03-12 |
2005-09-30 |
Pg Txl Co |
Kompozycja farmaceutyczna zawierająca lek przeciwnowotworowy i jej zastosowania
|
|
JPH09255590A
(ja)
*
|
1996-03-21 |
1997-09-30 |
Japan Synthetic Rubber Co Ltd |
徐放性薬剤
|
|
US6030941A
(en)
*
|
1996-05-01 |
2000-02-29 |
Avi Biopharma, Inc. |
Polymer composition for delivering substances in living organisms
|
|
US5929198A
(en)
*
|
1996-07-16 |
1999-07-27 |
Nalco Chemical Company |
Biodegradable poly (amino acid)s, derivatized amino acid polymers and methods for making same
|
|
US5900228A
(en)
*
|
1996-07-31 |
1999-05-04 |
California Institute Of Technology |
Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye
|
|
US5965118A
(en)
*
|
1997-04-18 |
1999-10-12 |
Access Pharmaceuticals, Inc. |
Polymer-platinum compounds
|
|
US6251866B1
(en)
*
|
1997-08-05 |
2001-06-26 |
Watson Laboratories, Inc. |
Conjugates targeted to the interleukin-2 receptor
|
|
US6229009B1
(en)
*
|
1997-08-29 |
2001-05-08 |
Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) |
Polycarboxylic based cross-linked copolymers
|
|
US6528061B1
(en)
*
|
1997-09-04 |
2003-03-04 |
Pasteur Institut |
Immunogenic polypeptides that mimic a surface polysaccharide antigen of a pathogenic microorganism, method for obtaining the same, and their use in vaccine compositions
|
|
JP3390965B2
(ja)
*
|
1997-09-12 |
2003-03-31 |
理化学研究所 |
糖結合スフィンゴシンを含有するポリマー化合物
|
|
US6391336B1
(en)
*
|
1997-09-22 |
2002-05-21 |
Royer Biomedical, Inc. |
Inorganic-polymer complexes for the controlled release of compounds including medicinals
|
|
WO2000038735A1
(fr)
*
|
1998-12-24 |
2000-07-06 |
Kyowa Hakko Kogyo Co., Ltd. |
Preparation pharmaceutique
|
|
US6716452B1
(en)
*
|
2000-08-22 |
2004-04-06 |
New River Pharmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
|
US20040121954A1
(en)
*
|
1999-04-13 |
2004-06-24 |
Xu Wuhan Jingya |
Poly(dipeptide) as a drug carrier
|
|
US20010041189A1
(en)
*
|
1999-04-13 |
2001-11-15 |
Jingya Xu |
Poly(dipeptide) as a drug carrier
|
|
AUPQ014799A0
(en)
*
|
1999-05-04 |
1999-05-27 |
Access Pharmaceuticals Australia Pty Limited |
Amplification of folate-mediated targeting to tumor cells using polymers
|
|
US6600788B1
(en)
*
|
1999-09-10 |
2003-07-29 |
Xilinx, Inc. |
Narrow-band filter including sigma-delta modulator implemented in a programmable logic device
|
|
US20030054977A1
(en)
*
|
1999-10-12 |
2003-03-20 |
Cell Therapeutics, Inc. |
Manufacture of polyglutamate-therapeutic agent conjugates
|
|
MXPA02003719A
(es)
*
|
1999-10-12 |
2002-08-30 |
Cell Therapeutics Inc |
Fabricacion de congujados de poliglutamato-agente terapeutico.
|
|
US6136846A
(en)
*
|
1999-10-25 |
2000-10-24 |
Supergen, Inc. |
Formulation for paclitaxel
|
|
US6235264B1
(en)
*
|
1999-12-01 |
2001-05-22 |
General Electric Company |
Medical imaging method for characterizing tumor angiogenesis using polymeric contrast agents
|
|
CA2396702C
(en)
*
|
2000-01-04 |
2010-03-23 |
Access Pharmaceuticals, Inc. |
N,o-amidomalonate platinum complexes
|
|
US7166733B2
(en)
*
|
2000-01-04 |
2007-01-23 |
Access Pharmaceuticals, Inc. |
O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes
|
|
US20020077290A1
(en)
*
|
2000-03-17 |
2002-06-20 |
Rama Bhatt |
Polyglutamic acid-camptothecin conjugates and methods of preparation
|
|
KR20020082888A
(ko)
*
|
2000-03-17 |
2002-10-31 |
쎌세러퓨틱스,인코포레이티드 |
폴리글루탐산-캄프토테신 컨주게이트 및 제조 방법
|
|
AU2001275525B2
(en)
*
|
2000-06-14 |
2007-04-26 |
Medarex, Inc. |
Tripeptide prodrug compounds
|
|
GB0018240D0
(en)
*
|
2000-07-25 |
2000-09-13 |
Pharmacia & Upjohn Spa |
Polymeric conjugates of antitumor agents
|
|
WO2002026241A1
(en)
*
|
2000-09-26 |
2002-04-04 |
Center For Advanced Science And Technology Incubation, Ltd. |
Polymeric micelle containing cisplatin enclosed therein and use thereof
|
|
US7070797B2
(en)
*
|
2000-11-07 |
2006-07-04 |
Dana Farber Cancer Institute, Inc. |
Method of treating hematologic tumors and cancers
|
|
ES2343679T3
(es)
*
|
2001-06-20 |
2010-08-06 |
Nippon Kayaku Kabushiki Kaisha |
Copolimeros de bloques con bajo contenido de impurezas; vehiculo polimerico; preparaciones farmaceuticas en forma polimerica y procedimiento para la preparacion del mismo.
|
|
US20030109432A1
(en)
*
|
2001-12-10 |
2003-06-12 |
Zuo William W. |
Anticancer polypeptide-metal complexes and compositions, methods of making, and methods of using same
|
|
US6939538B2
(en)
*
|
2002-04-11 |
2005-09-06 |
Biomedical Research Models, Inc. |
Extended release analgesic for pain control
|
|
FR2840614B1
(fr)
*
|
2002-06-07 |
2004-08-27 |
Flamel Tech Sa |
Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
|
|
JP2004018494A
(ja)
*
|
2002-06-19 |
2004-01-22 |
Japan Science & Technology Corp |
ブロック共重合体−薬剤複合体の製造法
|
|
US20040047835A1
(en)
*
|
2002-09-06 |
2004-03-11 |
Cell Therapeutics, Inc. |
Combinatorial drug therapy using polymer drug conjugates
|
|
US6855695B2
(en)
*
|
2003-06-13 |
2005-02-15 |
Vion Pharmaceuticals, Inc. |
Water-soluble SHPs as novel alkylating agents
|
|
US20050118718A1
(en)
*
|
2003-09-22 |
2005-06-02 |
University Of Utah Research Foundation |
Stabilization and controlled delivery of ionic biopharmaceuticals
|
|
US20050187147A1
(en)
*
|
2003-09-22 |
2005-08-25 |
Newman Michael J. |
Compositions and methods for increasing drug efficiency
|
|
CA2548457C
(en)
*
|
2003-12-10 |
2010-08-24 |
Toudai Tlo, Ltd. |
Coordination complex of diaminocyclohexaneplatinum(ii) with block copolymer containing poly(carboxylic acid) segment and antitumor agent comprising the same
|
|
WO2005063304A2
(en)
*
|
2003-12-24 |
2005-07-14 |
Board Of Regents, The University Of Texas_System |
Poly (l-glutamic acid) paramagnetic material complex and use as a biodegradable mri contrast agent
|
|
KR20050104152A
(ko)
*
|
2004-04-28 |
2005-11-02 |
최승호 |
경구용 약물의 흡수를 증진하는 약제학적 조성물
|
|
TW200616604A
(en)
*
|
2004-08-26 |
2006-06-01 |
Nicholas Piramal India Ltd |
Nitric oxide releasing prodrugs containing bio-cleavable linker
|
|
US20090137626A1
(en)
*
|
2005-07-12 |
2009-05-28 |
Akira Okuno |
Pharmaceutical Composition Containing PPARgamma Agonist
|
|
JP5237821B2
(ja)
*
|
2005-12-05 |
2013-07-17 |
日東電工株式会社 |
ポリグルタミン酸−アミノ酸結合体および方法
|
|
US20080051603A1
(en)
*
|
2006-06-15 |
2008-02-28 |
Cell Therapeutics, Inc. |
Process for the preparation of poly-alpha-glutamic acid and derivatives thereof
|