JP2010527346A5 - - Google Patents

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Publication number
JP2010527346A5
JP2010527346A5 JP2010507981A JP2010507981A JP2010527346A5 JP 2010527346 A5 JP2010527346 A5 JP 2010527346A5 JP 2010507981 A JP2010507981 A JP 2010507981A JP 2010507981 A JP2010507981 A JP 2010507981A JP 2010527346 A5 JP2010527346 A5 JP 2010527346A5
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JP
Japan
Prior art keywords
methyl
phenylpyrrolidin
quinolin
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010507981A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010527346A (ja
JP5474768B2 (ja
Filing date
Publication date
Priority claimed from GB0709489A external-priority patent/GB0709489D0/en
Priority claimed from GB0807591A external-priority patent/GB0807591D0/en
Application filed filed Critical
Priority claimed from PCT/GB2008/001694 external-priority patent/WO2008142384A1/en
Publication of JP2010527346A publication Critical patent/JP2010527346A/ja
Publication of JP2010527346A5 publication Critical patent/JP2010527346A5/ja
Application granted granted Critical
Publication of JP5474768B2 publication Critical patent/JP5474768B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010507981A 2007-05-17 2008-05-16 臨床的に潜伏性の微生物を殺傷するための４−（ピロリジン−１−イル）キノリン化合物の使用 Expired - Fee Related JP5474768B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0709489A GB0709489D0 (en) 2007-05-17 2007-05-17 New use
GB0709489.9 2007-05-17
GB0807591.3 2008-04-25
GB0807591A GB0807591D0 (en) 2008-04-25 2008-04-25 New use
PCT/GB2008/001694 WO2008142384A1 (en) 2007-05-17 2008-05-16 Use of 4-(pyrrolidin-1-yl)quinoline compounds to kill clinically latent microorganisms

Publications (3)

Publication Number Publication Date
JP2010527346A JP2010527346A (ja) 2010-08-12
JP2010527346A5 true JP2010527346A5 (enExample) 2011-06-30
JP5474768B2 JP5474768B2 (ja) 2014-04-16

Family

ID=39672613

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010507981A Expired - Fee Related JP5474768B2 (ja) 2007-05-17 2008-05-16 臨床的に潜伏性の微生物を殺傷するための４−（ピロリジン−１−イル）キノリン化合物の使用

Country Status (20)

Country Link
US (1) US8759348B2 (enExample)
EP (1) EP2182950B8 (enExample)
JP (1) JP5474768B2 (enExample)
KR (1) KR101599384B1 (enExample)
CN (1) CN101795688B (enExample)
AU (1) AU2008252636B2 (enExample)
BR (1) BRPI0811745B1 (enExample)
CA (1) CA2684692C (enExample)
DK (1) DK2182950T3 (enExample)
ES (1) ES2637999T3 (enExample)
HR (1) HRP20171553T1 (enExample)
HU (1) HUE034298T2 (enExample)
IL (1) IL201392A (enExample)
MX (1) MX2009012390A (enExample)
NZ (1) NZ580625A (enExample)
PL (1) PL2182950T3 (enExample)
PT (1) PT2182950T (enExample)
RU (1) RU2520766C2 (enExample)
SI (1) SI2182950T1 (enExample)
WO (1) WO2008142384A1 (enExample)

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JP2010095522A (ja) * 2008-09-19 2010-04-30 Sumitomo Chemical Co Ltd 植物病原菌による植物病害を防除又は予防するための農業用組成物
SI2552440T1 (sl) 2010-03-30 2019-03-29 Helperby Therapeutics Limited Nove kombinacije in uporaba
EP2569302A1 (en) * 2010-05-13 2013-03-20 Amgen, Inc Heteroaryloxyheterocyclyl compounds as pde10 inhibitors
GB201013207D0 (en) 2010-08-05 2010-09-22 Helperby Therapeutics Ltd Novel combination
WO2012017215A1 (en) 2010-08-05 2012-02-09 Helperby Therapeutics Limited Combination of a pyrroloquinoline compound and a beta-lactam antimicrobial agent, mupirocin or chlorhexidine
GB201015079D0 (en) 2010-09-10 2010-10-27 Helperby Therapeutics Ltd Novel use
JP6804096B2 (ja) 2015-04-11 2020-12-23 ヘルパービー セラピューティクス リミテッドＨｅｌｐｅｒｂｙ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ 口腔用組成物
US10329257B2 (en) 2015-08-13 2019-06-25 The Broad Institute, Inc. Compositions and methods for treating tuberculosis
GB201518969D0 (en) 2015-10-27 2015-12-09 Helperby Therapeutics Ltd Triple combination
US11253511B2 (en) 2016-01-04 2022-02-22 The Johns Hopkins University Use of low dose emetine for inhibition of human cytomegalovirus (HCMV)
KR102665309B1 (ko) * 2016-10-27 2024-05-10 주식회사 엘지생활건강 코디세핀을 포함하는 구강질환 예방 또는 치료용 조성물
GB201703898D0 (en) 2017-03-10 2017-04-26 Helperby Therapeautics Ltd Method
RU2664177C1 (ru) * 2017-08-07 2018-08-15 федеральное государственное бюджетное образовательное учреждение высшего образования "Омский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО ОмГМУ Минздрава России) Способ лечения абсцедирующих фурункулов верхней и нижней зон лица
CN111163766A (zh) * 2017-08-17 2020-05-15 医肯纳肿瘤学公司 Ahr抑制剂和其用途
US10668046B2 (en) 2017-12-18 2020-06-02 Ansella Therapeutics, Inc. Compositions and methods for preventing and treating conditions
CN110897032B (zh) * 2019-11-19 2025-10-14 华南理工大学 一种发酵饲料蛋白及其制备方法与应用
RU2758056C2 (ru) * 2019-11-21 2021-10-26 федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" Препарат для лечения отитов бактериальной и грибковой этиологии у собак
CN111544599B (zh) * 2020-07-10 2020-12-01 有术肌肤管理(深圳)有限公司 一种用于治疗痤疮的化合物及其用于制备药物或化妆品的用途
KR102461715B1 (ko) * 2020-10-12 2022-11-02 대한민국 항균 및 항진균 활성을 나타내는 신균주 페니실리움 비세티 및 이의 용도
CN114831924A (zh) * 2021-03-17 2022-08-02 武汉恒信源药业有限公司 一种乌洛托品及其化合物的阴道局部给药制剂及用途
CN113528388A (zh) * 2021-07-19 2021-10-22 海南大学 珊瑚共生链霉菌、发酵生产放线菌素d的方法及应用
SMT202500447T1 (it) 2021-11-02 2026-01-12 Flare Therapeutics Inc Agonisti inversi di pparg e loro usi
JP2025513455A (ja) 2022-04-22 2025-04-24 バーテックス ファーマシューティカルズ インコーポレイテッド 疼痛の治療のためのヘテロアリール化合物
CN117323339A (zh) * 2023-09-05 2024-01-02 中国科学院广州生物医药与健康研究院 偶氮丝氨酸在制备抗分枝杆菌的药物中的应用

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TW477787B (en) * 1996-08-27 2002-03-01 Pfizer Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same
EP2048142A3 (en) * 2001-04-26 2009-04-22 Eisai R&D Management Co., Ltd. Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof
AU2002338896B2 (en) * 2001-05-21 2006-04-27 F.Hoffman-La Roche Ag Quinoline derivatives as ligands for the neuropeptide Y receptor
US6787558B2 (en) * 2001-09-28 2004-09-07 Hoffmann-La Roche Inc. Quinoline derivatives
EP1451156A4 (en) * 2001-11-27 2005-05-25 Merck & Co Inc 4-AMINOCHINOLINVERBINDUNGEN
PL372295A1 (en) * 2002-02-04 2005-07-11 F.Hoffmann-La Roche Ag Quinoline derivatives as npy antagonists
CA2489560A1 (en) * 2002-06-27 2004-01-08 Schering Aktiengesellschaft Substituted quinoline ccr5 receptor antagonists
WO2004016321A2 (en) * 2002-08-19 2004-02-26 Avi Elbaz Proprioceptive/kinesthetic apparatus and method
JP4602903B2 (ja) * 2002-10-10 2010-12-22 モルフォケム アクチェンゲゼルシャフト フュア コンビナトリシェ ヘミー 抗菌活性を有する新規化合物
CL2004000409A1 (es) * 2003-03-03 2005-01-07 Vertex Pharma Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu
DE102004041163A1 (de) * 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
WO2006071875A1 (en) 2004-12-29 2006-07-06 Millennium Pharmaceuticals, Inc. Compounds useful as chemokine receptor antagonists
US20060183763A1 (en) * 2004-12-31 2006-08-17 Pfizer Inc Novel pyrrolidyl derivatives of heteroaromatic compounds
GB0522715D0 (en) * 2005-11-08 2005-12-14 Helperby Therapeutics Ltd New use

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