JP2010519915A5 - - Google Patents
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- Publication number
- JP2010519915A5 JP2010519915A5 JP2009552038A JP2009552038A JP2010519915A5 JP 2010519915 A5 JP2010519915 A5 JP 2010519915A5 JP 2009552038 A JP2009552038 A JP 2009552038A JP 2009552038 A JP2009552038 A JP 2009552038A JP 2010519915 A5 JP2010519915 A5 JP 2010519915A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleoside
- analog
- integer
- inosine
- cytosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90546107P | 2007-03-07 | 2007-03-07 | |
| US95027107P | 2007-07-17 | 2007-07-17 | |
| PCT/CA2008/000473 WO2008106803A1 (en) | 2007-03-07 | 2008-03-07 | Double-stranded locked nucleic acid compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010519915A JP2010519915A (ja) | 2010-06-10 |
| JP2010519915A5 true JP2010519915A5 (enExample) | 2011-10-27 |
Family
ID=39737757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009552038A Abandoned JP2010519915A (ja) | 2007-03-07 | 2008-03-07 | 二本鎖のロックされた核酸組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20090041809A1 (enExample) |
| EP (1) | EP2125853A1 (enExample) |
| JP (1) | JP2010519915A (enExample) |
| KR (1) | KR20100051041A (enExample) |
| CN (1) | CN101687900A (enExample) |
| AU (1) | AU2008222523A1 (enExample) |
| BR (1) | BRPI0808442A2 (enExample) |
| CA (1) | CA2680060A1 (enExample) |
| MX (1) | MX2009009530A (enExample) |
| WO (1) | WO2008106803A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0228540D0 (en) * | 2002-12-06 | 2003-01-15 | Glaxo Group Ltd | Novel compositions |
| WO2009149470A1 (en) | 2008-06-06 | 2009-12-10 | Aurora Biofuels, Inc. | Vcp-based vectors for algal cell transformation |
| KR101701198B1 (ko) | 2008-06-19 | 2017-02-01 | 배리에이션 바이오테크놀로지스 아이엔씨. | 인플루엔자를 치료하기 위한 조성물 및 방법 |
| JP2012520761A (ja) | 2009-03-19 | 2012-09-10 | イー・エム・デイー・ミリポア・コーポレイシヨン | ナノ繊維濾過媒体を用いる、流体資料からの微生物の除去 |
| US20110097418A1 (en) * | 2009-05-29 | 2011-04-28 | Variation Biotechnologies, Inc. | Compositions and methods for treating influenza |
| US8865468B2 (en) | 2009-10-19 | 2014-10-21 | Aurora Algae, Inc. | Homologous recombination in an algal nuclear genome |
| US9029137B2 (en) | 2009-06-08 | 2015-05-12 | Aurora Algae, Inc. | ACP promoter |
| US8809046B2 (en) | 2011-04-28 | 2014-08-19 | Aurora Algae, Inc. | Algal elongases |
| CA2803282C (en) | 2009-07-06 | 2018-05-01 | David E. Anderson | Methods for preparing vesicles and formulations produced therefrom |
| BR112012000826B1 (pt) | 2009-07-06 | 2022-07-26 | Variation Biotechnologies Inc | Método para a preparação de vesículas |
| US8709765B2 (en) | 2009-07-20 | 2014-04-29 | Aurora Algae, Inc. | Manipulation of an alternative respiratory pathway in photo-autotrophs |
| WO2011041789A1 (en) | 2009-10-02 | 2011-04-07 | The Trustees Of Columbia University In The City Of New York | Piscine reovirus immunogenic compositions |
| US8846388B2 (en) * | 2009-10-16 | 2014-09-30 | Zoetis Llc | Infectious clones of torque teno virus |
| US8492358B2 (en) * | 2010-06-25 | 2013-07-23 | Idera Pharmaceuticals, Inc. | Agonists of toll-like receptor 3 and methods of their use |
| WO2012006367A2 (en) | 2010-07-06 | 2012-01-12 | Variation Biotechnologies, Inc. | Compositions and methods for treating influenza |
| US9623352B2 (en) | 2010-08-10 | 2017-04-18 | Emd Millipore Corporation | Method for retrovirus removal |
| PL2655612T3 (pl) | 2010-12-23 | 2017-12-29 | Shell Internationale Research Maatschappij B.V. | Czynniki uszkadzające geny produkujące pochodne tłuszczowego acylo-coa |
| CA2862864C (en) | 2011-01-13 | 2018-12-11 | Variation Biotechnologies Inc. | Compositions and methods for treating viral infections |
| US20130323280A1 (en) | 2011-01-13 | 2013-12-05 | Variation Biotechnologies, Inc. | Methods for preparing vesicles and formulations produced therefrom |
| US8722359B2 (en) | 2011-01-21 | 2014-05-13 | Aurora Algae, Inc. | Genes for enhanced lipid metabolism for accumulation of lipids |
| SG10201605328WA (en) | 2011-04-01 | 2016-08-30 | Emd Millipore Corp | Nanofiber containing composite structures |
| JP2014519810A (ja) | 2011-04-28 | 2014-08-21 | オーロラ アルギー,インコーポレイテッド | 藻類のデサチュラーゼ |
| US8980865B2 (en) | 2011-12-22 | 2015-03-17 | Alios Biopharma, Inc. | Substituted nucleotide analogs |
| EP2802353A4 (en) | 2012-01-12 | 2015-12-02 | Variation Biotechnologies Inc | COMPOSITIONS AND METHOD FOR THE TREATMENT OF VIRUS INFECTIONS |
| CN104244984B (zh) | 2012-01-27 | 2020-03-31 | 变异生物技术公司 | 用于治疗剂的方法和组合物 |
| US8916538B2 (en) | 2012-03-21 | 2014-12-23 | Vertex Pharmaceuticals Incorporated | Solid forms of a thiophosphoramidate nucleotide prodrug |
| US9157101B2 (en) | 2012-12-21 | 2015-10-13 | Algenol Biotech LLC | Cyanobacterium sp. for production of compounds |
| AR095882A1 (es) | 2013-04-22 | 2015-11-18 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9 |
| US9994831B2 (en) | 2013-12-12 | 2018-06-12 | The Regents Of The University Of California | Methods and compositions for modifying a single stranded target nucleic acid |
| SG10201911354UA (en) | 2014-06-26 | 2020-02-27 | Emd Millipore Corp | Filter structure with enhanced dirt holding capacity |
| WO2016061131A1 (en) | 2014-10-14 | 2016-04-21 | The J. David Gladstone Institutes | Compositions and methods for reactivating latent immunodeficiency virus |
| AU2015371292A1 (en) | 2014-12-23 | 2017-07-20 | Algenol Biotech LLC | Methods for increasing the stability of production of compounds in microbial host cells |
| KR102206959B1 (ko) | 2015-04-17 | 2021-01-25 | 이엠디 밀리포어 코포레이션 | 접선방향 유동 여과 모드에서 작동되는 나노섬유 한외여과막을 사용하여 샘플에서 목적하는 생물학적 물질을 정제하는 방법 |
| WO2016196655A1 (en) | 2015-06-03 | 2016-12-08 | The Regents Of The University Of California | Cas9 variants and methods of use thereof |
| US10138489B2 (en) | 2016-10-20 | 2018-11-27 | Algenol Biotech LLC | Cyanobacterial strains capable of utilizing phosphite |
| JP7159308B2 (ja) | 2017-07-21 | 2022-10-24 | メルク・ミリポア・リミテッド | ラテラルフローデバイスおよびこれを用いる試料中の検体を検出する方法 |
| EP3690030A4 (en) | 2017-09-28 | 2021-06-23 | Industry-Academic Cooperation Foundation, Yonsei University | METHOD FOR MANUFACTURING MYELOID-DERIVED SUPPRESSOR CELLS, SUPPRESSOR CELLS MANUFACTURED FROM MYEOLID AND USES THEREOF |
| BR112020022294A2 (pt) * | 2018-05-04 | 2021-02-23 | Tollys | composição e uso de uma composição |
| WO2020041456A1 (en) | 2018-08-22 | 2020-02-27 | The Regents Of The University Of California | Variant type v crispr/cas effector polypeptides and methods of use thereof |
| AU2019374883A1 (en) | 2018-11-09 | 2021-05-20 | Inari Agriculture Technology, Inc. | RNA-guided nucleases and DNA binding proteins |
| EP3935156A4 (en) | 2019-03-07 | 2022-12-28 | The Regents of The University of California | CRISPR-CAS EFFECTIVE POLYPEPTIDES AND METHODS OF USE THEREOF |
| MX2022000134A (es) * | 2019-07-02 | 2022-05-19 | Na Vaccine Inst | Nuevo ácido ribonucleico y composición farmacéutica basada en el mismo. |
| KR102256001B1 (ko) * | 2019-07-02 | 2021-05-26 | 주식회사 엔에이백신연구소 | 신규한 리보핵산 및 이를 기반으로 하는 약제학적 조성물 |
| US20230302158A1 (en) * | 2020-08-14 | 2023-09-28 | Allen Institute | Artificial expression constructs for modulating gene expression in striatal neurons |
| JP2024517181A (ja) | 2021-04-28 | 2024-04-19 | ウエヌイグレックオ・ファーマ | 組合せ治療としてfxrアゴニストを使用するtlr3アゴニストの効果の強い増強 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3692899A (en) * | 1969-12-17 | 1972-09-19 | Us Health Education & Welfare | Inhibition of transplanted tumor growth by polyinosinic-polycytidylic acid in mice |
| US4024241A (en) * | 1974-09-27 | 1977-05-17 | The United States Of America As Represented By The Secretary Of Health, Education And Welfare | Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid |
| US3952097A (en) * | 1974-09-27 | 1976-04-20 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid |
| US4349538A (en) * | 1979-12-07 | 1982-09-14 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid |
| US6239116B1 (en) * | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| DE69535905D1 (de) * | 1994-07-15 | 2009-02-26 | Coley Pharm Group Inc | Immunomodulatorische Oligonukleotide |
| US7157089B1 (en) * | 1996-11-26 | 2007-01-02 | Stressgen Biotechnologies Corporation | Immune responses using compositions containing stress proteins |
| JP3756313B2 (ja) * | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| CA2203843C (en) * | 1997-04-28 | 2013-07-23 | Her Majesty The Queen, In Right Of Canada, As Represented By The Ministe R Of National Defence | Liposome-encapsulated poly iclc |
| US6794499B2 (en) * | 1997-09-12 | 2004-09-21 | Exiqon A/S | Oligonucleotide analogues |
| US6083482A (en) * | 1999-05-11 | 2000-07-04 | Icn Pharmaceuticals, Inc. | Conformationally locked nucleosides and oligonucleotides |
| AT410173B (de) * | 2000-06-08 | 2003-02-25 | Cistem Biotechnologies Gmbh | Antigene zusammensetzung |
| JP2005526497A (ja) * | 2002-02-04 | 2005-09-08 | ビオミラ,インコーポレーテッド | 免疫刺激性、共有結合性脂質化オリゴヌクレオチド |
| US7439349B2 (en) * | 2002-07-03 | 2008-10-21 | Andres Salazar | Method for preparation of large volume batches of poly-ICLC with increased biological potency; therapeutic, clinical and veterinary uses thereof |
| GB0228540D0 (en) * | 2002-12-06 | 2003-01-15 | Glaxo Group Ltd | Novel compositions |
| CA2542232A1 (en) * | 2003-06-09 | 2005-01-20 | Alnylam Pharmaceuticals, Inc. | Method for treating neurodegenerative disease by inhibiting alpha-synuclein |
| WO2006054129A1 (en) * | 2004-11-19 | 2006-05-26 | Institut Gustave Roussy | Improved treatment of cancer by double-stranded rna |
| US7834064B2 (en) * | 2005-01-03 | 2010-11-16 | Andres Mario Salazar | Clinical method for the immunomodulatory and vaccine adjuvant use of poly-ICLC and other dsRNAs |
| WO2007050990A2 (en) * | 2005-10-27 | 2007-05-03 | Rosetta Inpharmatics Llc | Nucleic acid amplification using non-random primers |
| CA2627585A1 (en) * | 2005-11-01 | 2007-05-10 | Alnylam Pharmaceuticals, Inc. | Rnai inhibition of influenza virus replication |
-
2008
- 2008-03-07 MX MX2009009530A patent/MX2009009530A/es not_active Application Discontinuation
- 2008-03-07 BR BRPI0808442-4A patent/BRPI0808442A2/pt not_active IP Right Cessation
- 2008-03-07 EP EP08733577A patent/EP2125853A1/en not_active Withdrawn
- 2008-03-07 AU AU2008222523A patent/AU2008222523A1/en not_active Abandoned
- 2008-03-07 US US12/044,895 patent/US20090041809A1/en not_active Abandoned
- 2008-03-07 KR KR1020097020608A patent/KR20100051041A/ko not_active Withdrawn
- 2008-03-07 CN CN200880014144A patent/CN101687900A/zh active Pending
- 2008-03-07 JP JP2009552038A patent/JP2010519915A/ja not_active Abandoned
- 2008-03-07 WO PCT/CA2008/000473 patent/WO2008106803A1/en not_active Ceased
- 2008-03-07 CA CA002680060A patent/CA2680060A1/en not_active Abandoned
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