JP2009504190A5 - - Google Patents
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- Publication number
- JP2009504190A5 JP2009504190A5 JP2008527139A JP2008527139A JP2009504190A5 JP 2009504190 A5 JP2009504190 A5 JP 2009504190A5 JP 2008527139 A JP2008527139 A JP 2008527139A JP 2008527139 A JP2008527139 A JP 2008527139A JP 2009504190 A5 JP2009504190 A5 JP 2009504190A5
- Authority
- JP
- Japan
- Prior art keywords
- strand
- nucleotide
- nucleic acid
- double
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 230000000692 anti-sense effect Effects 0.000 claims 7
- 108091081021 Sense strand Proteins 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 150000007523 nucleic acids Chemical class 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 claims 4
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 claims 2
- 239000005547 deoxyribonucleotide Substances 0.000 claims 2
- 125000002637 deoxyribonucleotide group Chemical group 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 244000089409 Erythrina poeppigiana Species 0.000 claims 1
- 235000009776 Rathbunia alamosensis Nutrition 0.000 claims 1
- 108091028664 Ribonucleotide Proteins 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000002336 ribonucleotide Substances 0.000 claims 1
- 125000002652 ribonucleotide group Chemical group 0.000 claims 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/205,646 US20080161256A1 (en) | 2001-05-18 | 2005-08-17 | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
| US11/234,730 US20070270579A1 (en) | 2001-05-18 | 2005-09-23 | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
| US73702405P | 2005-11-15 | 2005-11-15 | |
| US11/299,254 US20060217331A1 (en) | 2001-05-18 | 2005-12-08 | Chemically modified double stranded nucleic acid molecules that mediate RNA interference |
| PCT/US2006/032168 WO2007022369A2 (en) | 2005-08-17 | 2006-08-17 | Chemically modified short interfering nucleic acid molecules that mediate rna interference |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009504190A JP2009504190A (ja) | 2009-02-05 |
| JP2009504190A5 true JP2009504190A5 (enExample) | 2011-02-24 |
Family
ID=40328218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008527139A Pending JP2009504190A (ja) | 2005-08-17 | 2006-08-17 | Ｒｎａ干渉を媒介する化学修飾低分子干渉核酸分子 |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP2009504190A (enExample) |
| BR (1) | BRPI0614407A2 (enExample) |
| IL (1) | IL189540A0 (enExample) |
| MX (1) | MX2008002369A (enExample) |
| NO (1) | NO20081376L (enExample) |
| NZ (1) | NZ565712A (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8315398B2 (en) | 2007-12-21 | 2012-11-20 | Dts Llc | System for adjusting perceived loudness of audio signals |
| JP5730508B2 (ja) * | 2009-07-10 | 2015-06-10 | アンジェスＭｇ株式会社 | 炎症性腸疾患の治療又は予防剤 |
| US8538042B2 (en) | 2009-08-11 | 2013-09-17 | Dts Llc | System for increasing perceived loudness of speakers |
| US9312829B2 (en) | 2012-04-12 | 2016-04-12 | Dts Llc | System for adjusting loudness of audio signals in real time |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050233996A1 (en) * | 2002-02-20 | 2005-10-20 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of hairless (HR) gene expression using short interfering nucleic acid (siNA) |
| AU2003207708A1 (en) * | 2002-02-20 | 2003-09-09 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of map kinase genes |
-
2006
- 2006-08-17 JP JP2008527139A patent/JP2009504190A/ja active Pending
- 2006-08-17 MX MX2008002369A patent/MX2008002369A/es active IP Right Grant
- 2006-08-17 NZ NZ565712A patent/NZ565712A/en not_active IP Right Cessation
- 2006-08-17 BR BRPI0614407-1A patent/BRPI0614407A2/pt not_active IP Right Cessation
-
2008
- 2008-02-14 IL IL189540A patent/IL189540A0/en unknown
- 2008-03-14 NO NO20081376A patent/NO20081376L/no not_active Application Discontinuation
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