JP2010519300A5 - - Google Patents
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- Publication number
- JP2010519300A5 JP2010519300A5 JP2009550930A JP2009550930A JP2010519300A5 JP 2010519300 A5 JP2010519300 A5 JP 2010519300A5 JP 2009550930 A JP2009550930 A JP 2009550930A JP 2009550930 A JP2009550930 A JP 2009550930A JP 2010519300 A5 JP2010519300 A5 JP 2010519300A5
- Authority
- JP
- Japan
- Prior art keywords
- crystalline form
- incontinence
- form according
- formula
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 7
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 206010021639 Incontinence Diseases 0.000 claims 3
- 208000002193 Pain Diseases 0.000 claims 3
- 206010046543 Urinary incontinence Diseases 0.000 claims 3
- 239000013078 crystal Substances 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 208000019901 Anxiety disease Diseases 0.000 claims 2
- 230000036506 anxiety Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 208000011580 syndromic disease Diseases 0.000 claims 2
- 238000001757 thermogravimetry curve Methods 0.000 claims 2
- 230000001457 vasomotor Effects 0.000 claims 2
- 208000000094 Chronic Pain Diseases 0.000 claims 1
- 208000034347 Faecal incontinence Diseases 0.000 claims 1
- 206010016825 Flushing Diseases 0.000 claims 1
- KYYIDSXMWOZKMP-UHFFFAOYSA-N O-desmethylvenlafaxine Chemical compound C1CCCCC1(O)C(CN(C)C)C1=CC=C(O)C=C1 KYYIDSXMWOZKMP-UHFFFAOYSA-N 0.000 claims 1
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 claims 1
- 206010066218 Stress Urinary Incontinence Diseases 0.000 claims 1
- 208000000921 Urge Urinary Incontinence Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 230000002411 adverse Effects 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000004442 gravimetric analysis Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000000634 powder X-ray diffraction Methods 0.000 claims 1
- 230000011514 reflex Effects 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 claims 1
- 229960004688 venlafaxine Drugs 0.000 claims 1
- -1 water Chemical compound 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90295007P | 2007-02-21 | 2007-02-21 | |
| US60/902,950 | 2007-02-21 | ||
| PCT/US2008/002379 WO2008103461A2 (en) | 2007-02-21 | 2008-02-21 | Solid forms comprising (-) o-desmethylvenlafaxine and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010519300A JP2010519300A (ja) | 2010-06-03 |
| JP2010519300A5 true JP2010519300A5 (enExample) | 2011-04-07 |
| JP5666140B2 JP5666140B2 (ja) | 2015-02-12 |
Family
ID=39432564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009550930A Expired - Fee Related JP5666140B2 (ja) | 2007-02-21 | 2008-02-21 | （−）−ｏ−デスメチルベンラファキシンを含む固形物およびそれらの使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20090005457A1 (enExample) |
| EP (2) | EP2114863B1 (enExample) |
| JP (1) | JP5666140B2 (enExample) |
| KR (1) | KR101528326B1 (enExample) |
| CN (1) | CN101663263A (enExample) |
| AR (1) | AR065431A1 (enExample) |
| AU (1) | AU2008218997B2 (enExample) |
| BR (1) | BRPI0807604A2 (enExample) |
| CA (1) | CA2678599C (enExample) |
| ES (1) | ES2609264T3 (enExample) |
| IL (1) | IL200514A (enExample) |
| MX (1) | MX2009008705A (enExample) |
| NZ (2) | NZ579137A (enExample) |
| RU (1) | RU2477269C2 (enExample) |
| SG (1) | SG175611A1 (enExample) |
| TW (1) | TWI446903B (enExample) |
| WO (1) | WO2008103461A2 (enExample) |
| ZA (1) | ZA200905698B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100015923A (ko) * | 2007-04-09 | 2010-02-12 | 세프라코 아이엔시. | 수면관련 호흡 장애를 치료하는 방법들 및 수면관련 호흡 장애 치료용 조성물들 |
| CZ2008756A3 (cs) * | 2008-11-27 | 2010-03-24 | Zentiva, A. S. | Zpusob prípravy desvenlafaxinu a jeho solí |
| CZ302145B6 (cs) * | 2009-07-15 | 2010-11-10 | Zentiva, K. S. | Zpusob prípravy desvenlafaxinu a jeho solí |
| CN102249936B (zh) * | 2010-05-19 | 2014-09-17 | 江苏豪森医药集团有限公司 | O-去甲基文拉法辛盐酸盐的水合物及其制备方法 |
| CA2773948A1 (en) * | 2011-04-12 | 2012-10-12 | Geo. Pfau's Sons Company, Inc. | Method for rendering animal materials |
| CN103772220A (zh) * | 2013-12-03 | 2014-05-07 | 镇江圣安医药有限公司 | 1-[2-二甲基氨基-1-（4-甲氧基苯基）乙基]环己醇的新型衍生物及其应用 |
| CN105348119B (zh) * | 2015-11-04 | 2017-09-15 | 江苏豪森药业集团有限公司 | 晶状的文拉法辛代谢物及其制备方法 |
| WO2018146529A1 (en) * | 2017-02-09 | 2018-08-16 | R L Finechem Private Limited | A process for preparation of1-[2-(dimethylamino)-1-(4-hydroxyphenyl) ethyl]-cyclohexanol and salts thereof |
| CN109771380A (zh) * | 2017-11-10 | 2019-05-21 | 连云港恒运药业有限公司 | 去甲文拉法辛盐酸盐药物组合物及其制备方法 |
| JP7315256B2 (ja) | 2018-12-05 | 2023-07-26 | ヘッジホッグ，インコーポレイテッド | エンドセリン受容体ａ活性調節抗体 |
| WO2021243351A2 (en) * | 2020-05-26 | 2021-12-02 | Mars, Incorporated | Process for preparing pet food and pet food obtainable thereby |
| CN116199590B (zh) * | 2022-12-26 | 2024-12-24 | 湖北美林药业有限公司 | 一种盐酸多巴酚丁胺及其注射剂 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5213738A (en) | 1990-05-15 | 1993-05-25 | L. Perrigo Company | Method for making a capsule-shaped tablet |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US6342533B1 (en) | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
| AU5738700A (en) * | 1999-06-15 | 2001-01-02 | American Home Products Corporation | Enantiomers of o-desmethyl venlafaxine |
| BR0207157A (pt) * | 2001-02-12 | 2004-02-17 | Wyeth Corp | Sal de succinato de o-desmetil-venlafaxina |
| IL162255A0 (en) * | 2001-12-05 | 2005-11-20 | Wyeth Corp | Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof |
| NZ537142A (en) | 2002-06-10 | 2008-01-31 | Wyeth Corp | Novel formate salt of O-desmethyl-venlafaxine |
| JP2009500420A (ja) * | 2005-07-06 | 2009-01-08 | セプラコア インコーポレーテッド | エスゾピクロン及びｏ−デスメチルベンラファキシンの組み合わせ、並びに閉経期並びに気分、不安、及び認知障害の治療方法 |
-
2008
- 2008-02-21 EP EP08725968.5A patent/EP2114863B1/en active Active
- 2008-02-21 US US12/070,888 patent/US20090005457A1/en not_active Abandoned
- 2008-02-21 ES ES08725968.5T patent/ES2609264T3/es active Active
- 2008-02-21 CA CA2678599A patent/CA2678599C/en active Active
- 2008-02-21 NZ NZ579137A patent/NZ579137A/en not_active IP Right Cessation
- 2008-02-21 ZA ZA200905698A patent/ZA200905698B/xx unknown
- 2008-02-21 CN CN200880012483A patent/CN101663263A/zh active Pending
- 2008-02-21 TW TW097106132A patent/TWI446903B/zh not_active IP Right Cessation
- 2008-02-21 NZ NZ599480A patent/NZ599480A/xx not_active IP Right Cessation
- 2008-02-21 AU AU2008218997A patent/AU2008218997B2/en not_active Ceased
- 2008-02-21 WO PCT/US2008/002379 patent/WO2008103461A2/en not_active Ceased
- 2008-02-21 SG SG2011074085A patent/SG175611A1/en unknown
- 2008-02-21 EP EP12164795A patent/EP2500337A3/en not_active Withdrawn
- 2008-02-21 AR ARP080100726A patent/AR065431A1/es not_active Application Discontinuation
- 2008-02-21 BR BRPI0807604-9A patent/BRPI0807604A2/pt not_active Application Discontinuation
- 2008-02-21 RU RU2009135016/04A patent/RU2477269C2/ru active
- 2008-02-21 KR KR1020097019715A patent/KR101528326B1/ko not_active Expired - Fee Related
- 2008-02-21 JP JP2009550930A patent/JP5666140B2/ja not_active Expired - Fee Related
- 2008-02-21 MX MX2009008705A patent/MX2009008705A/es active IP Right Grant
-
2009
- 2009-08-20 IL IL200514A patent/IL200514A/en active IP Right Grant
-
2016
- 2016-05-25 US US15/164,394 patent/US20160355457A1/en not_active Abandoned
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