JP2010511018A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010511018A5 JP2010511018A5 JP2009538725A JP2009538725A JP2010511018A5 JP 2010511018 A5 JP2010511018 A5 JP 2010511018A5 JP 2009538725 A JP2009538725 A JP 2009538725A JP 2009538725 A JP2009538725 A JP 2009538725A JP 2010511018 A5 JP2010511018 A5 JP 2010511018A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- compound
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86814406P | 2006-12-01 | 2006-12-01 | |
| PCT/EP2007/063106 WO2008065198A1 (en) | 2006-12-01 | 2007-11-30 | Triazolopyridine compounds useful for the treatment of degenerative & inflammatory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010511018A JP2010511018A (ja) | 2010-04-08 |
| JP2010511018A5 true JP2010511018A5 (https=) | 2010-11-25 |
Family
ID=38983774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009538725A Pending JP2010511018A (ja) | 2006-12-01 | 2007-11-30 | 変性疾患及び炎症性疾患の治療に有用なトリアゾロピリジン化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7977352B2 (https=) |
| EP (1) | EP2086540B8 (https=) |
| JP (1) | JP2010511018A (https=) |
| AT (1) | ATE495743T1 (https=) |
| DE (1) | DE602007012133D1 (https=) |
| WO (1) | WO2008065198A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2411930T3 (es) | 2008-02-20 | 2013-07-09 | Actelion Pharmaceuticals Ltd. | Compuestos antibióticos azatricíclicos |
| RU2501799C2 (ru) | 2008-02-22 | 2013-12-20 | Актелион Фармасьютикалз Лтд | Поизводные оксазолидинона |
| JO3041B1 (ar) * | 2008-07-25 | 2016-09-05 | Galapagos Nv | مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية |
| BRPI0920895A8 (pt) | 2008-10-07 | 2017-12-26 | Actelion Pharmaceuticals Ltd | Compostos antibióticos de oxazolidinona tricíclica |
| KR101667066B1 (ko) | 2008-10-10 | 2016-10-17 | 액테리온 파마슈티칼 리미티드 | 옥사졸리디닐 항생제 |
| CN102459258B (zh) | 2009-06-05 | 2015-11-25 | 赛福伦公司 | 1,2,4-三唑并[1,5a]吡啶衍生物的制备和用途 |
| JP2011168582A (ja) * | 2010-01-21 | 2011-09-01 | Ishihara Sangyo Kaisha Ltd | トリアゾロピリジン誘導体又はその塩、それらの製造方法及びそれらを含有する有害生物防除剤 |
| MA38884A1 (fr) | 2013-09-05 | 2017-06-30 | Hoffmann La Roche | Composé de triazolopyridine, compositions et procédés d'utilisation associés |
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| SI3105218T1 (sl) | 2014-02-13 | 2019-11-29 | Incyte Corp | Ciklopropilamini kot inhibitorji LSD1 |
| MX373103B (es) | 2014-02-13 | 2020-04-17 | Incyte Holdings Corp | Ciclopropilaminas como inhibidores de desmetilasa específica de lisina 1 (lsd1). |
| EP3105219B9 (en) | 2014-02-13 | 2018-10-03 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| TW201613925A (en) | 2014-07-10 | 2016-04-16 | Incyte Corp | Imidazopyrazines as LSD1 inhibitors |
| TWI687419B (zh) | 2014-07-10 | 2020-03-11 | 美商英塞特公司 | 作為ｌｓｄ１抑制劑之咪唑并吡啶及咪唑并吡嗪 |
| WO2016007727A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| EP3277689B1 (en) | 2015-04-03 | 2019-09-04 | Incyte Corporation | Heterocyclic compounds as lsd1 inhibitors |
| LT3334709T (lt) | 2015-08-12 | 2025-03-10 | Incyte Holdings Corporation | Lsd1 inhibitoriaus druskos |
| JP6999574B2 (ja) | 2016-04-22 | 2022-01-18 | インサイト・コーポレイション | Ｌｓｄ１阻害剤の製剤 |
| WO2018000549A1 (zh) * | 2016-06-29 | 2018-01-04 | 四川大学华西医院 | [1,2,4]三唑并[1,5-a]吡啶衍生物及其晶型 |
| US10071079B2 (en) | 2016-06-29 | 2018-09-11 | Bristol-Myers Squibb Company | [1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds |
| BR112019001270A2 (pt) | 2016-07-30 | 2019-04-30 | Bristol-Myers Squibb Company | compostos indol substituídos com dimetoxifenila como inibidores de tlr7, tlr8 ou tlr9 |
| JP7028861B2 (ja) | 2016-09-09 | 2022-03-02 | ブリストル－マイヤーズ スクイブ カンパニー | ピリジル置換のインドール化合物 |
| JP7117293B2 (ja) | 2016-09-16 | 2022-08-12 | ヘルムホルツ ツェントゥルム ミュンヘン ドイチェス フォルシュングスツェントゥルム フューア ゲズントハイト ウント ウムヴェルト （ゲーエムベーハー） | Ｔｒａｆ６阻害剤 |
| WO2019028302A1 (en) | 2017-08-04 | 2019-02-07 | Bristol-Myers Squibb Company | SUBSTITUTED INDOLE COMPOUNDS USEFUL AS TLR7 / 8/9 INHIBITORS |
| KR102688509B1 (ko) | 2017-08-04 | 2024-07-24 | 브리스톨-마이어스 스큅 컴퍼니 | [1,2,4]트리아졸로[4,3-a]피리디닐 치환된 인돌 화합물 |
| JP7265554B2 (ja) | 2017-11-14 | 2023-04-26 | ブリストル－マイヤーズ スクイブ カンパニー | 置換インドール化合物 |
| KR102781141B1 (ko) | 2017-12-15 | 2025-03-13 | 브리스톨-마이어스 스큅 컴퍼니 | 치환된 인돌 에테르 화합물 |
| EA202091484A1 (ru) | 2017-12-18 | 2021-03-25 | Бристол-Маерс Сквибб Компани | 4-азаиндольные соединения |
| MX2020005462A (es) | 2017-12-19 | 2020-09-07 | Bristol Myers Squibb Co | Compuestos de indol sustituidos utiles como inhibidores de receptores tipo toll (tlr). |
| WO2019126081A1 (en) | 2017-12-19 | 2019-06-27 | Bristol-Myers Squibb Company | Amide substituted indole compounds useful as tlr inhibitors |
| JP7304352B2 (ja) | 2017-12-19 | 2023-07-06 | ブリストル－マイヤーズ スクイブ カンパニー | ６－アザインドール化合物 |
| SG11202005733QA (en) | 2017-12-20 | 2020-07-29 | Bristol Myers Squibb Co | Diazaindole compounds |
| EP3728218B1 (en) | 2017-12-20 | 2021-12-01 | Bristol-Myers Squibb Company | Amino indole compounds useful as tlr inhibitors |
| KR102730859B1 (ko) | 2017-12-20 | 2024-11-15 | 브리스톨-마이어스 스큅 컴퍼니 | 아릴 및 헤테로아릴 치환된 인돌 화합물 |
| WO2020047198A1 (en) | 2018-08-31 | 2020-03-05 | Incyte Corporation | Salts of an lsd1 inhibitor and processes for preparing the same |
| CN112955450A (zh) | 2018-10-24 | 2021-06-11 | 百时美施贵宝公司 | 经取代的吲哚和吲唑化合物 |
| ES2963696T3 (es) | 2018-10-24 | 2024-04-01 | Bristol Myers Squibb Co | Compuestos diméricos de indol sustituidos |
| KR102904576B1 (ko) | 2019-05-09 | 2025-12-24 | 브리스톨-마이어스 스큅 컴퍼니 | 치환된 벤즈이미다졸론 화합물 |
| EP4041730A1 (en) | 2019-10-01 | 2022-08-17 | Bristol-Myers Squibb Company | Substituted bicyclic heteroaryl compounds |
| CN114829350B (zh) | 2019-10-04 | 2024-05-28 | 百时美施贵宝公司 | 经取代的咔唑化合物 |
| AU2021361057A1 (en) * | 2020-10-16 | 2023-06-08 | Rarefied Biosciences, Inc. | Malt1 modulators and uses thereof |
| CN121866258A (zh) * | 2023-08-18 | 2026-04-14 | 薛定谔公司 | 治疗癌症的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6355653B1 (en) * | 1999-09-06 | 2002-03-12 | Hoffmann-La Roche Inc. | Amino-triazolopyridine derivatives |
| AU2003249477A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Heterobicylcic metalloproteinase inhibitors |
| US7576085B2 (en) | 2002-09-23 | 2009-08-18 | Schering Corporation | Imidazopyrazines as cyclin dependent kinase inhibitors |
| TW200413378A (en) | 2002-09-23 | 2004-08-01 | Schering Corp | Novel imidazopyrazines as cyclin dependent kinase inhibitors |
| US20080033006A1 (en) | 2004-01-26 | 2008-02-07 | Altana Pharma Ag | 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors |
| CA2570319A1 (en) * | 2004-06-25 | 2006-01-12 | Amgen Inc. | Condensed triazoles and indazoles useful in treating citokines mediated diseases and other diseases |
| TW200804386A (en) | 2005-11-10 | 2008-01-16 | Schering Corp | Imidazopyrazines as protein kinase inhibitors |
| US7893058B2 (en) | 2006-05-15 | 2011-02-22 | Janssen Pharmaceutica Nv | Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
| PT2029602E (pt) | 2006-05-31 | 2010-07-08 | Galapagos Nv | Compostos de triazolopirazina uteis para o tratamento de doenãas degenerativas e inflamatërias |
| JP2010511019A (ja) | 2006-12-01 | 2010-04-08 | ガラパゴス・ナムローゼ・フェンノートシャップ | 変性疾患及び炎症性疾患の治療に有用なイミダゾロピリジン化合物 |
-
2007
- 2007-11-30 JP JP2009538725A patent/JP2010511018A/ja active Pending
- 2007-11-30 EP EP07857236A patent/EP2086540B8/en not_active Not-in-force
- 2007-11-30 DE DE602007012133T patent/DE602007012133D1/de active Active
- 2007-11-30 US US11/998,817 patent/US7977352B2/en not_active Expired - Fee Related
- 2007-11-30 AT AT07857236T patent/ATE495743T1/de not_active IP Right Cessation
- 2007-11-30 WO PCT/EP2007/063106 patent/WO2008065198A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010511018A5 (https=) | ||
| JP2010511019A5 (https=) | ||
| RU2403258C2 (ru) | Тиазолилдигидроиндазолы | |
| JP2020169171A5 (https=) | ||
| RU2442778C9 (ru) | Новые соединения, действующие как ингибиторы erk | |
| JP2024050527A5 (https=) | ||
| RU2350605C2 (ru) | Аналоги хиназолина в качестве ингибиторов рецепторных тирозинкиназ | |
| RU2007109870A (ru) | 2,4-ди(аминофенил)пиримидины в качестве ингибиторов plk-киназ | |
| RU2020110780A (ru) | Ингибитор fgfr и его медицинское применение | |
| RU2019100164A (ru) | Гетероциклическое соединение, используемое как ингибитор fgfr | |
| RU2016150486A (ru) | Ингибиторы бета-лактамазы | |
| JP2008510691A5 (https=) | ||
| JP2006524660A5 (https=) | ||
| RU2008152087A (ru) | Макроциклические оксимильные ингибиторы протеазы гепатита | |
| JP2019522055A5 (https=) | ||
| JP2013526559A5 (https=) | ||
| JP2017508789A5 (https=) | ||
| CA2394327A1 (en) | Substituted piperazine and piperidine calcium channel blockers | |
| RU2011133128A (ru) | Противоопухолевые соединения дигидропиран-2-она | |
| RU2019116590A (ru) | Трициклические гетероциклические соединения, полезные в качестве ингибиторов интегразы вич | |
| RU2013108348A (ru) | Конденсированные гетероарилы и их применение | |
| JP2021527125A5 (https=) | ||
| JPWO2020123827A5 (https=) | ||
| RU2006116628A (ru) | Новые производные имидазола и их применение в качестве фармацевтических агентов | |
| JP2015536947A5 (https=) |