JP2010511018A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010511018A5 JP2010511018A5 JP2009538725A JP2009538725A JP2010511018A5 JP 2010511018 A5 JP2010511018 A5 JP 2010511018A5 JP 2009538725 A JP2009538725 A JP 2009538725A JP 2009538725 A JP2009538725 A JP 2009538725A JP 2010511018 A5 JP2010511018 A5 JP 2010511018A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- compound
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86814406P | 2006-12-01 | 2006-12-01 | |
| PCT/EP2007/063106 WO2008065198A1 (en) | 2006-12-01 | 2007-11-30 | Triazolopyridine compounds useful for the treatment of degenerative & inflammatory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010511018A JP2010511018A (ja) | 2010-04-08 |
| JP2010511018A5 true JP2010511018A5 (enExample) | 2010-11-25 |
Family
ID=38983774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009538725A Pending JP2010511018A (ja) | 2006-12-01 | 2007-11-30 | 変性疾患及び炎症性疾患の治療に有用なトリアゾロピリジン化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7977352B2 (enExample) |
| EP (1) | EP2086540B8 (enExample) |
| JP (1) | JP2010511018A (enExample) |
| AT (1) | ATE495743T1 (enExample) |
| DE (1) | DE602007012133D1 (enExample) |
| WO (1) | WO2008065198A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0907892A2 (pt) | 2008-02-20 | 2015-07-28 | Actelion Pharmaceuticals Ltd | Composto antibiótico azatricíclico, medicamento, composição farmacêutica que o contém e uso do mesmo |
| CA2713187C (en) | 2008-02-22 | 2016-06-07 | Actelion Pharmaceuticals Ltd | Oxazolidinone derivatives |
| JO3041B1 (ar) * | 2008-07-25 | 2016-09-05 | Galapagos Nv | مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية |
| JP4833385B1 (ja) | 2008-10-07 | 2011-12-07 | アクテリオン ファーマシューティカルズ リミテッド | 三環式オキサゾリジノン抗生物質化合物 |
| JP5490809B2 (ja) | 2008-10-10 | 2014-05-14 | アクテリオン ファーマシューティカルズ リミテッド | オキサゾリジニル抗生物質 |
| WO2010141796A2 (en) | 2009-06-05 | 2010-12-09 | Cephalon, Inc. | PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES |
| JP2011168582A (ja) * | 2010-01-21 | 2011-09-01 | Ishihara Sangyo Kaisha Ltd | トリアゾロピリジン誘導体又はその塩、それらの製造方法及びそれらを含有する有害生物防除剤 |
| JP6472803B2 (ja) | 2013-09-05 | 2019-02-20 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | トリアゾロピリジン化合物、その組成物及び使用方法 |
| LT3105218T (lt) | 2014-02-13 | 2019-12-10 | Incyte Corp | Ciklopropilaminai kaip lsd1 inhibitoriai |
| EP3392244A1 (en) | 2014-02-13 | 2018-10-24 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| WO2015123424A1 (en) | 2014-02-13 | 2015-08-20 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| WO2016007731A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyridines and imidazopyrazines as lsd1 inhibitors |
| WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| US9758523B2 (en) | 2014-07-10 | 2017-09-12 | Incyte Corporation | Triazolopyridines and triazolopyrazines as LSD1 inhibitors |
| WO2016007736A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyrazines as lsd1 inhibitors |
| EA201792205A1 (ru) | 2015-04-03 | 2018-02-28 | Инсайт Корпорейшн | Гетероциклические соединения как ингибиторы lsd1 |
| DK3334709T3 (da) | 2015-08-12 | 2025-02-03 | Incyte Holdings Corp | Salte af en lsd1-hæmmer |
| CA3021678A1 (en) | 2016-04-22 | 2017-10-26 | Incyte Corporation | Formulations of an lsd1 inhibitor |
| US10071079B2 (en) | 2016-06-29 | 2018-09-11 | Bristol-Myers Squibb Company | [1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds |
| WO2018000549A1 (zh) * | 2016-06-29 | 2018-01-04 | 四川大学华西医院 | [1,2,4]三唑并[1,5-a]吡啶衍生物及其晶型 |
| CN109715617B (zh) | 2016-07-30 | 2022-04-19 | 百时美施贵宝公司 | 作为tlr7、tlr8或tlr9抑制剂的二甲氧基苯基取代的吲哚化合物 |
| ES2902504T3 (es) | 2016-09-09 | 2022-03-28 | Bristol Myers Squibb Co | Compuestos de indol sustituidos con piridilo |
| CA3032210A1 (en) | 2016-09-16 | 2018-03-22 | Helmholtz Zentrum Muenchen - Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) | Traf 6 inhibitors |
| CN110997670B (zh) | 2017-08-04 | 2022-11-01 | 百时美施贵宝公司 | [1,2,4]三唑并[4,3-a]吡啶基取代的吲哚化合物 |
| EP3661926B1 (en) | 2017-08-04 | 2022-02-23 | Bristol-Myers Squibb Company | Substituted indole compounds useful as inhibitors of tlr7/8/9 |
| CN111448190B (zh) | 2017-11-14 | 2023-09-26 | 百时美施贵宝公司 | 取代的吲哚化合物 |
| US12030878B2 (en) | 2017-12-15 | 2024-07-09 | Bristol-Myers Squibb Company | Substituted indole ether compounds |
| MX2020006168A (es) | 2017-12-18 | 2020-08-13 | Bristol Myers Squibb Co | Compuestos de 4-azaindol. |
| EP3728253B1 (en) | 2017-12-19 | 2024-03-27 | Bristol-Myers Squibb Company | 6-azaindole compounds |
| WO2019126081A1 (en) | 2017-12-19 | 2019-06-27 | Bristol-Myers Squibb Company | Amide substituted indole compounds useful as tlr inhibitors |
| EA202091474A1 (ru) | 2017-12-19 | 2020-11-18 | Бристол-Маерс Сквибб Компани | Замещенные индольные соединения, применимые в качестве ингибиторов tlr |
| KR102730859B1 (ko) | 2017-12-20 | 2024-11-15 | 브리스톨-마이어스 스큅 컴퍼니 | 아릴 및 헤테로아릴 치환된 인돌 화합물 |
| JP7287967B2 (ja) | 2017-12-20 | 2023-06-06 | ブリストル－マイヤーズ スクイブ カンパニー | Ｔｌｒ阻害剤として有効なアミノインドール化合物 |
| EA202091530A1 (ru) | 2017-12-20 | 2020-09-14 | Бристол-Маерс Сквибб Компани | Диазаиндольные соединения |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
| ES2963696T3 (es) | 2018-10-24 | 2024-04-01 | Bristol Myers Squibb Co | Compuestos diméricos de indol sustituidos |
| US12172995B2 (en) | 2018-10-24 | 2024-12-24 | Bristol-Myers Squibb Company | Substituted indole and indazole compounds |
| KR102904576B1 (ko) | 2019-05-09 | 2025-12-24 | 브리스톨-마이어스 스큅 컴퍼니 | 치환된 벤즈이미다졸론 화합물 |
| WO2021067326A1 (en) | 2019-10-01 | 2021-04-08 | Bristol-Myers Squibb Company | Substituted bicyclic heteroaryl compounds |
| CN114829350B (zh) | 2019-10-04 | 2024-05-28 | 百时美施贵宝公司 | 经取代的咔唑化合物 |
| WO2022081967A1 (en) * | 2020-10-16 | 2022-04-21 | Rheos Medicines, Inc. | Malt1 modulators and uses thereof |
| EP4762056A1 (en) * | 2023-08-18 | 2026-06-24 | Schrödinger, Inc. | Methods of treating cancer |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6355653B1 (en) | 1999-09-06 | 2002-03-12 | Hoffmann-La Roche Inc. | Amino-triazolopyridine derivatives |
| AU2003249477A1 (en) * | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Heterobicylcic metalloproteinase inhibitors |
| US7576085B2 (en) * | 2002-09-23 | 2009-08-18 | Schering Corporation | Imidazopyrazines as cyclin dependent kinase inhibitors |
| JP4799864B2 (ja) * | 2002-09-23 | 2011-10-26 | シェーリング コーポレイション | サイクリン依存性キナーゼインヒビターとしてのイミダゾピラジン |
| US20080033006A1 (en) * | 2004-01-26 | 2008-02-07 | Altana Pharma Ag | 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors |
| JP2008504294A (ja) * | 2004-06-25 | 2008-02-14 | アムジエン・インコーポレーテツド | サイトカイン介在疾患および他の疾患の治療において有用な縮合トリアゾールおよびインダゾール |
| EP1945644A2 (en) * | 2005-11-10 | 2008-07-23 | Schering Corporation | Imidazopyrazines as protein kinase inhibitors |
| US7893058B2 (en) | 2006-05-15 | 2011-02-22 | Janssen Pharmaceutica Nv | Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
| HRP20100378T1 (hr) | 2006-05-31 | 2010-08-31 | Galapagos N.V. | Spojevi triazolopirazina učinkoviti za tretman degenerativnih i upalnih bolesti |
| EP2099798A1 (en) * | 2006-12-01 | 2009-09-16 | Galapagos N.V. | Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases |
-
2007
- 2007-11-30 AT AT07857236T patent/ATE495743T1/de not_active IP Right Cessation
- 2007-11-30 US US11/998,817 patent/US7977352B2/en not_active Expired - Fee Related
- 2007-11-30 EP EP07857236A patent/EP2086540B8/en not_active Not-in-force
- 2007-11-30 WO PCT/EP2007/063106 patent/WO2008065198A1/en not_active Ceased
- 2007-11-30 DE DE602007012133T patent/DE602007012133D1/de active Active
- 2007-11-30 JP JP2009538725A patent/JP2010511018A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010511019A5 (enExample) | ||
| JP2020169171A5 (enExample) | ||
| RU2007116858A (ru) | Тиазолилдигидроиндазолы | |
| RU2442778C9 (ru) | Новые соединения, действующие как ингибиторы erk | |
| JP2024050527A5 (enExample) | ||
| RU2350605C2 (ru) | Аналоги хиназолина в качестве ингибиторов рецепторных тирозинкиназ | |
| RU2007109870A (ru) | 2,4-ди(аминофенил)пиримидины в качестве ингибиторов plk-киназ | |
| RU2019100164A (ru) | Гетероциклическое соединение, используемое как ингибитор fgfr | |
| RU2020110780A (ru) | Ингибитор fgfr и его медицинское применение | |
| RU2016150486A (ru) | Ингибиторы бета-лактамазы | |
| JP2008510691A5 (enExample) | ||
| JP2006524660A5 (enExample) | ||
| RU2013108348A (ru) | Конденсированные гетероарилы и их применение | |
| JP2019522055A5 (enExample) | ||
| JP2011509309A5 (enExample) | ||
| RU2011133128A (ru) | Противоопухолевые соединения дигидропиран-2-она | |
| JP2013526559A5 (enExample) | ||
| JP2017508789A5 (enExample) | ||
| JP2013532652A5 (enExample) | ||
| JP2021527125A5 (enExample) | ||
| CA2394327A1 (en) | Substituted piperazine and piperidine calcium channel blockers | |
| JP2016509047A5 (enExample) | ||
| RU2019116590A (ru) | Трициклические гетероциклические соединения, полезные в качестве ингибиторов интегразы вич | |
| JP2019500387A5 (enExample) | ||
| RU2006116628A (ru) | Новые производные имидазола и их применение в качестве фармацевтических агентов |