JP2010507594A5 - - Google Patents
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- Publication number
- JP2010507594A5 JP2010507594A5 JP2009533598A JP2009533598A JP2010507594A5 JP 2010507594 A5 JP2010507594 A5 JP 2010507594A5 JP 2009533598 A JP2009533598 A JP 2009533598A JP 2009533598 A JP2009533598 A JP 2009533598A JP 2010507594 A5 JP2010507594 A5 JP 2010507594A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- antigen
- binding fragment
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85326006P | 2006-10-20 | 2006-10-20 | |
| PCT/US2007/082164 WO2008133706A2 (en) | 2006-10-20 | 2007-10-22 | Fully human anti-vegf antibodies and methods of using |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010507594A JP2010507594A (ja) | 2010-03-11 |
| JP2010507594A5 true JP2010507594A5 (enExample) | 2010-12-09 |
Family
ID=39926241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009533598A Pending JP2010507594A (ja) | 2006-10-20 | 2007-10-22 | 完全ヒト抗ｖｅｇｆ抗体および使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110076279A1 (enExample) |
| EP (1) | EP2086583A4 (enExample) |
| JP (1) | JP2010507594A (enExample) |
| CN (1) | CN102006885A (enExample) |
| CA (1) | CA2666974A1 (enExample) |
| MX (1) | MX2009004027A (enExample) |
| WO (1) | WO2008133706A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE028379T2 (en) * | 2006-09-29 | 2016-12-28 | Oncomed Pharm Inc | Preparations and procedures for the diagnosis and treatment of cancer |
| US8216571B2 (en) * | 2007-10-22 | 2012-07-10 | Schering Corporation | Fully human anti-VEGF antibodies and methods of using |
| KR101093717B1 (ko) * | 2008-11-26 | 2011-12-19 | 한국생명공학연구원 | Ｖｅｇｆ―특이적인 인간항체 |
| WO2010124009A2 (en) * | 2009-04-21 | 2010-10-28 | Schering Corporation | Fully human anti-vegf antibodies and methods of using |
| AU2010245011B2 (en) * | 2009-04-27 | 2015-09-03 | Oncomed Pharmaceuticals, Inc. | Method for making heteromultimeric molecules |
| CN102002104A (zh) * | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
| US8883145B2 (en) | 2009-10-16 | 2014-11-11 | Oncomed Pharmaceuticals, Inc. | Methods of treatment with DLL4 antagonists and an anti-hypertensive agent |
| CN102167740B (zh) * | 2010-02-25 | 2014-06-04 | 上海百迈博制药有限公司 | 一种全人源抗vegf单克隆抗体、其制备方法及用途 |
| US20120225081A1 (en) | 2010-09-03 | 2012-09-06 | Boehringer Ingelheim International Gmbh | Vegf-binding molecules |
| US8551479B2 (en) | 2010-09-10 | 2013-10-08 | Oncomed Pharmaceuticals, Inc. | Methods for treating melanoma |
| US9527925B2 (en) | 2011-04-01 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules binding to VEGF and ANG2 |
| CN102757495A (zh) * | 2011-04-26 | 2012-10-31 | 中国人民解放军第二军医大学 | 一种全人源抗vegf抗体、其制备方法及用途 |
| CN102875676B (zh) * | 2011-07-13 | 2014-11-05 | 无锡天演生物技术有限公司 | 全人源抗人vegf单抗分子及其应用 |
| SI3485903T1 (sl) | 2011-09-23 | 2023-02-28 | Mereo Biopharma 5, Inc. | Sredstva, ki vežejo VEGF/DLL4, in njihove uporabe |
| US9599620B2 (en) | 2012-10-31 | 2017-03-21 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a DLL4 antagonist |
| WO2014104406A1 (ja) * | 2012-12-27 | 2014-07-03 | 学校法人慶應義塾 | 骨粗鬆症治療剤及び治療剤のスクリーニング方法 |
| CN105263959A (zh) * | 2013-12-31 | 2016-01-20 | 财团法人生物技术开发中心 | 抗vegf抗体及其用途 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| US20160176962A1 (en) | 2014-10-31 | 2016-06-23 | Oncomed Pharmaceuticals, Inc. | Combination Therapy For Treatment Of Disease |
| ES2968074T3 (es) | 2015-09-23 | 2024-05-07 | Mereo Biopharma 5 Inc | Anticuerpo bi-específico anti-VEGF/DLL4 para su uso en el tratamiento del cáncer de ovario resistente al platino |
| WO2017094733A1 (ja) * | 2015-11-30 | 2017-06-08 | 日産化学工業株式会社 | 分子標的医薬に結合するｄｎａアプタマー及びそれを用いる分子標的医薬の検出方法 |
| KR20250057128A (ko) | 2015-12-30 | 2025-04-28 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| JP6949106B2 (ja) | 2016-08-23 | 2021-10-13 | メディミューン リミテッド | 抗ｖｅｇｆ−ａ抗体ならびにそれらの使用 |
| WO2019129679A1 (en) | 2017-12-29 | 2019-07-04 | F. Hoffmann-La Roche Ag | Method for improving vegf-receptor blocking selectivity of an anti-vegf antibody |
| US12071476B2 (en) | 2018-03-02 | 2024-08-27 | Kodiak Sciences Inc. | IL-6 antibodies and fusion constructs and conjugates thereof |
| JP7526728B2 (ja) * | 2018-12-21 | 2024-08-01 | エフ． ホフマン－ラ ロシュ アーゲー | 抗ｖｅｇｆ抗体のｖｅｇｆ－ｒ１への結合阻害を改善する方法 |
| WO2021013064A1 (zh) * | 2019-07-19 | 2021-01-28 | 神州细胞工程有限公司 | 一种人源化vegfr2抗体及其应用 |
| AU2020364071A1 (en) | 2019-10-10 | 2022-05-26 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| WO2023109904A1 (zh) * | 2021-12-16 | 2023-06-22 | 石药集团中奇制药技术（石家庄）有限公司 | 多西他赛白蛋白组合物与vegf抑制剂或vegfr抑制剂的组合及用途 |
| JP2025512923A (ja) * | 2022-03-30 | 2025-04-22 | シーアン オリマブ バイオテクノロジー カンパニー リミテッド | 抗ｐｓｍａ抗体、バリアント、及びその使用 |
| CN115850470B (zh) * | 2022-12-12 | 2023-07-07 | 三门峡市眼科医院 | Vegf抗体及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL132240A0 (en) * | 1997-04-07 | 2001-03-19 | Genentech Inc | Anti-vegf antibodies |
| IL155977A0 (en) * | 2000-11-30 | 2003-12-23 | Medarex Inc | Transgenic transchromosomal rodents for making human antibodies |
| US20050232921A1 (en) * | 2001-04-13 | 2005-10-20 | Rosen Craig A | Vascular endothelial growth factor 2 |
| US7667004B2 (en) * | 2001-04-17 | 2010-02-23 | Abmaxis, Inc. | Humanized antibodies against vascular endothelial growth factor |
| US20060073141A1 (en) * | 2001-06-28 | 2006-04-06 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
| EP1439192A1 (en) * | 2003-01-15 | 2004-07-21 | Xerion Pharmaceuticals AG | Neuropilin-1 inhibitors |
| ES2453973T3 (es) * | 2005-02-02 | 2014-04-09 | University Of Massachusetts | Anticuerpos humanos contra la rabia y usos de los mismos |
| US8216571B2 (en) * | 2007-10-22 | 2012-07-10 | Schering Corporation | Fully human anti-VEGF antibodies and methods of using |
-
2007
- 2007-10-22 CA CA002666974A patent/CA2666974A1/en not_active Abandoned
- 2007-10-22 CN CN2007800475418A patent/CN102006885A/zh active Pending
- 2007-10-22 EP EP07874227A patent/EP2086583A4/en not_active Withdrawn
- 2007-10-22 JP JP2009533598A patent/JP2010507594A/ja active Pending
- 2007-10-22 WO PCT/US2007/082164 patent/WO2008133706A2/en not_active Ceased
- 2007-10-22 MX MX2009004027A patent/MX2009004027A/es unknown
- 2007-10-22 US US12/446,438 patent/US20110076279A1/en not_active Abandoned
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