JP2014509510A5 - - Google Patents
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- JP2014509510A5 JP2014509510A5 JP2013556805A JP2013556805A JP2014509510A5 JP 2014509510 A5 JP2014509510 A5 JP 2014509510A5 JP 2013556805 A JP2013556805 A JP 2013556805A JP 2013556805 A JP2013556805 A JP 2013556805A JP 2014509510 A5 JP2014509510 A5 JP 2014509510A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- binding fragment
- seq
- chain variable
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449005P | 2011-03-03 | 2011-03-03 | |
| US61/449,005 | 2011-03-03 | ||
| PCT/US2012/026954 WO2012118813A2 (en) | 2011-03-03 | 2012-02-28 | Anti-il-6 receptor antibodies and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014509510A JP2014509510A (ja) | 2014-04-21 |
| JP2014509510A5 true JP2014509510A5 (enExample) | 2015-03-12 |
| JP6097702B2 JP6097702B2 (ja) | 2017-03-15 |
Family
ID=46753443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013556805A Expired - Fee Related JP6097702B2 (ja) | 2011-03-03 | 2012-02-28 | 抗ｉｌ−６受容体抗体およびその使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8753634B2 (enExample) |
| EP (1) | EP2681243B1 (enExample) |
| JP (1) | JP6097702B2 (enExample) |
| KR (1) | KR20140043724A (enExample) |
| CN (1) | CN103502274B (enExample) |
| AU (1) | AU2012223449A1 (enExample) |
| BR (1) | BR112013021863A2 (enExample) |
| CA (1) | CA2827581A1 (enExample) |
| IL (2) | IL228275A (enExample) |
| MX (1) | MX342810B (enExample) |
| RU (1) | RU2013144392A (enExample) |
| WO (1) | WO2012118813A2 (enExample) |
| ZA (1) | ZA201306451B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102002104A (zh) | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
| JP6097702B2 (ja) | 2011-03-03 | 2017-03-15 | アペクシジェン， インコーポレイテッド | 抗ｉｌ−６受容体抗体およびその使用方法 |
| US9487590B2 (en) | 2012-09-25 | 2016-11-08 | Cytomx Therapeutics, Inc. | Activatable antibodies that bind interleukin-6 receptor and methods of use thereof |
| US9290578B2 (en) * | 2013-10-21 | 2016-03-22 | Genentech, Inc. | Anti-Ly6E antibodies and methods of use |
| JP2016208934A (ja) * | 2015-05-12 | 2016-12-15 | 学校法人日本大学 | 抗イヌインターロイキン−６受容体モノクローナル抗体又は抗体フラグメント及びその利用 |
| CA3119498A1 (en) | 2015-07-31 | 2017-02-09 | Medimmune Limited | Methods for treating hepcidin-mediated disorders |
| WO2017201731A1 (en) * | 2016-05-27 | 2017-11-30 | Beijing Vdjbio Co., Ltd. | Antibodies, composition and kits comprising same, and methods of use thereof |
| US20190330318A1 (en) | 2016-07-25 | 2019-10-31 | Biogen Ma Inc. | Anti-hspa5 (grp78) antibodies and uses thereof |
| RU2656160C2 (ru) | 2016-08-17 | 2018-05-31 | Закрытое Акционерное Общество "Биокад" | Антитело или его антигенсвязывающий фрагмент, способный связываться с рецептором интерлейкина-6 человека |
| IL324632A (en) | 2016-12-01 | 2026-01-01 | Regeneron Pharma | Radiolabeled anti-PD-L1 antibodies for immuno-PET imaging |
| CN110072551B (zh) | 2016-12-14 | 2023-05-23 | 比奥拉治疗股份有限公司 | 使用利用可摄入装置释放的il-12/il-23抑制剂治疗胃肠道疾病 |
| CA3045310A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| WO2018112237A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor |
| TWI716668B (zh) | 2017-02-01 | 2021-01-21 | 耶魯大學 | 心臟衰竭及心腎症候群之精準治療 |
| EP3600416B1 (en) | 2017-03-30 | 2023-06-07 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| US20210139589A1 (en) * | 2017-06-22 | 2021-05-13 | Apexigen, Inc | Anti-vista antibodies and methods of use |
| US20190048072A1 (en) | 2017-06-22 | 2019-02-14 | Novartis Ag | USE OF IL-1beta BINDING ANTIBODIES |
| MX2020002750A (es) * | 2017-09-13 | 2020-07-20 | Jiangsu Hengrui Medicine Co | Anticuerpo il-6r y fragmento de union a antigeno y uso medico. |
| MX2020006882A (es) | 2018-01-05 | 2020-09-07 | Novo Nordisk As | Metodos para tratar inflamacion mediada por interleucina-6 sin inmunosupresion. |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| EP3810268A1 (en) | 2018-06-20 | 2021-04-28 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| JP7619939B2 (ja) | 2018-10-05 | 2025-01-22 | シアトル チルドレンズ ホスピタル ドゥーイング ビジネス アズ シアトル チルドレンズ リサーチ インスティテュート | 原発性免疫不全症、シスチン症、及びウィルソン病に関する新生児スクリーニング |
| EP3897613A1 (en) | 2018-12-21 | 2021-10-27 | Novartis AG | Use of il-1beta binding antibodies |
| WO2020213665A1 (ja) * | 2019-04-17 | 2020-10-22 | 国立大学法人広島大学 | Ｉｌ－６阻害剤及びｃｃｒ２阻害剤を組み合わせて投与することを特徴とする泌尿器がんの治療剤 |
| CN110124029B (zh) * | 2019-04-19 | 2023-08-11 | 中山大学附属第六医院 | Il-6r抗体及羊水干细胞在制备用于治疗nec的药物中的应用 |
| WO2021012176A1 (en) * | 2019-07-23 | 2021-01-28 | Shanghaitech University | Asic1 channel antagonist antibody |
| EP4126966A4 (en) | 2020-03-31 | 2024-08-07 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | PROTEOMIC SCREENING FOR LYSOSOMAL STORAGE DISEASES |
| US12523662B2 (en) | 2020-04-02 | 2026-01-13 | Seattle Children's Hospital | Antibodies that specifically bind peptides associated with the primary immunodeficiencies: Wiskott-Aldrich syndrome and x-linked agammaglobulinemia |
| EP4132952A4 (en) * | 2020-04-08 | 2024-10-02 | Nanopin Technologies, Inc. | MONOCLONAL ANTIBODIES AND THEIR USES |
| US12454580B2 (en) | 2020-04-10 | 2025-10-28 | Regeneron Pharmaceuticals, Inc. | FRB antibodies |
| WO2021207697A1 (en) | 2020-04-10 | 2021-10-14 | Cantex Pharmaceuticals, Inc. | Treatment of acute lung injury |
| US20230167182A1 (en) * | 2020-05-18 | 2023-06-01 | Biosion Inc. | Antibodies binding il6r and uses thereof |
| EP4171551A1 (en) | 2020-06-22 | 2023-05-03 | Tranquis Therapeutics, Inc. | Treatment of systemic immune activation syndromes |
| AR122933A1 (es) | 2020-07-10 | 2022-10-19 | Novo Nordisk As | Métodos para tratar la enfermedad cardiovascular |
| WO2022040604A1 (en) | 2020-08-21 | 2022-02-24 | BioAge Labs, Inc. | Use of dp1 receptor antagonists for the treatment of viral respiratory tract infections and dysregulated immune response in aged and aging patients |
| AU2021338354A1 (en) | 2020-09-02 | 2023-04-20 | Serhat GUMRUKCU | Expanded memory subsets of gamma delta T cells for immunotherapy |
| WO2022130409A1 (en) * | 2020-12-18 | 2022-06-23 | Dr. Reddy's Laboratories Limited | Il-6r targeting compositions with reduced heterogeneity in functional attributes |
| US20240200085A1 (en) | 2022-12-15 | 2024-06-20 | Aarhus Universitet | Synthetic activation of multimeric transmembrane receptors |
| CN118085075B (zh) * | 2023-11-29 | 2024-08-30 | 武汉爱博泰克生物科技有限公司 | 抗人甲胎蛋白的兔单克隆抗体及其应用 |
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-
2012
- 2012-02-28 JP JP2013556805A patent/JP6097702B2/ja not_active Expired - Fee Related
- 2012-02-28 US US13/407,293 patent/US8753634B2/en active Active
- 2012-02-28 MX MX2013009679A patent/MX342810B/es active IP Right Grant
- 2012-02-28 BR BR112013021863A patent/BR112013021863A2/pt not_active IP Right Cessation
- 2012-02-28 EP EP12752484.1A patent/EP2681243B1/en not_active Not-in-force
- 2012-02-28 AU AU2012223449A patent/AU2012223449A1/en not_active Abandoned
- 2012-02-28 KR KR1020137026011A patent/KR20140043724A/ko not_active Withdrawn
- 2012-02-28 CN CN201280021430.0A patent/CN103502274B/zh not_active Expired - Fee Related
- 2012-02-28 WO PCT/US2012/026954 patent/WO2012118813A2/en not_active Ceased
- 2012-02-28 CA CA2827581A patent/CA2827581A1/en not_active Abandoned
- 2012-02-28 RU RU2013144392/10A patent/RU2013144392A/ru not_active Application Discontinuation
-
2013
- 2013-08-27 ZA ZA2013/06451A patent/ZA201306451B/en unknown
- 2013-09-03 IL IL228275A patent/IL228275A/en active IP Right Grant
-
2014
- 2014-05-02 US US14/268,932 patent/US9951136B2/en active Active
-
2017
- 2017-04-16 IL IL251744A patent/IL251744A0/en unknown
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