JP2014509510A5 - - Google Patents
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- JP2014509510A5 JP2014509510A5 JP2013556805A JP2013556805A JP2014509510A5 JP 2014509510 A5 JP2014509510 A5 JP 2014509510A5 JP 2013556805 A JP2013556805 A JP 2013556805A JP 2013556805 A JP2013556805 A JP 2013556805A JP 2014509510 A5 JP2014509510 A5 JP 2014509510A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- binding fragment
- seq
- chain variable
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449005P | 2011-03-03 | 2011-03-03 | |
| US61/449,005 | 2011-03-03 | ||
| PCT/US2012/026954 WO2012118813A2 (en) | 2011-03-03 | 2012-02-28 | Anti-il-6 receptor antibodies and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014509510A JP2014509510A (ja) | 2014-04-21 |
| JP2014509510A5 true JP2014509510A5 (enExample) | 2015-03-12 |
| JP6097702B2 JP6097702B2 (ja) | 2017-03-15 |
Family
ID=46753443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013556805A Expired - Fee Related JP6097702B2 (ja) | 2011-03-03 | 2012-02-28 | 抗ｉｌ−６受容体抗体およびその使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8753634B2 (enExample) |
| EP (1) | EP2681243B1 (enExample) |
| JP (1) | JP6097702B2 (enExample) |
| KR (1) | KR20140043724A (enExample) |
| CN (1) | CN103502274B (enExample) |
| AU (1) | AU2012223449A1 (enExample) |
| BR (1) | BR112013021863A2 (enExample) |
| CA (1) | CA2827581A1 (enExample) |
| IL (2) | IL228275A (enExample) |
| MX (1) | MX342810B (enExample) |
| RU (1) | RU2013144392A (enExample) |
| WO (1) | WO2012118813A2 (enExample) |
| ZA (1) | ZA201306451B (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102002104A (zh) | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
| CN103502274B (zh) | 2011-03-03 | 2016-01-06 | 埃派斯进有限公司 | 抗-il-6受体抗体及其使用方法 |
| US9487590B2 (en) | 2012-09-25 | 2016-11-08 | Cytomx Therapeutics, Inc. | Activatable antibodies that bind interleukin-6 receptor and methods of use thereof |
| KR20160068963A (ko) | 2013-10-21 | 2016-06-15 | 제넨테크, 인크. | 항-Ly6E 항체 및 사용 방법 |
| JP2016208934A (ja) * | 2015-05-12 | 2016-12-15 | 学校法人日本大学 | 抗イヌインターロイキン−６受容体モノクローナル抗体又は抗体フラグメント及びその利用 |
| AU2016302768B2 (en) | 2015-07-31 | 2019-08-22 | Medimmune Limited | Methods for treating hepcidin-mediated disorders |
| WO2017201731A1 (en) * | 2016-05-27 | 2017-11-30 | Beijing Vdjbio Co., Ltd. | Antibodies, composition and kits comprising same, and methods of use thereof |
| MA45715A (fr) | 2016-07-25 | 2019-05-29 | Biogen Ma Inc | Anticorps anti-hspa5 (grp78) et leurs utilisations |
| RU2656160C2 (ru) * | 2016-08-17 | 2018-05-31 | Закрытое Акционерное Общество "Биокад" | Антитело или его антигенсвязывающий фрагмент, способный связываться с рецептором интерлейкина-6 человека |
| RS67792B1 (sr) | 2016-12-01 | 2026-03-31 | Regeneron Pharma | Radio-obeležena anti-pd-l1 antitela za imuno-pet snimanje |
| WO2018112232A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device |
| WO2018112237A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor |
| CA3045310A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| JP7630906B2 (ja) | 2017-02-01 | 2025-02-18 | イェール・ユニヴァーシティー | 利尿薬耐性の治療 |
| CA3054632A1 (en) | 2017-03-30 | 2018-10-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| CA3067835A1 (en) * | 2017-06-22 | 2018-12-27 | Apexigen, Inc. | Anti-vista antibodies and methods of use |
| WO2018234879A1 (en) | 2017-06-22 | 2018-12-27 | Novartis Ag | USE OF IL-1β BINDING ANTIBODIES IN THE TREATMENT OF CANCER |
| CN111051343B (zh) * | 2017-09-13 | 2022-11-22 | 江苏恒瑞医药股份有限公司 | Il-6r抗体、其抗原结合片段及医药用途 |
| SG11202006157VA (en) | 2018-01-05 | 2020-07-29 | Corvidia Therapeutics Inc | Methods for treating il-6 mediated inflammation without immunosuppression |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| WO2019246271A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
| US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| EP3861018A4 (en) | 2018-10-05 | 2022-10-26 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | NEWBORN SCREENING FOR PRIMARY IMMUNODEFICIENCY CYSTINosis AND WILSON'S DISEASE |
| US20220025036A1 (en) | 2018-12-21 | 2022-01-27 | Novartis Ag | Use of il-1beta binding antibodies |
| AU2020259884A1 (en) * | 2019-04-17 | 2021-10-07 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination |
| CN110124029B (zh) * | 2019-04-19 | 2023-08-11 | 中山大学附属第六医院 | Il-6r抗体及羊水干细胞在制备用于治疗nec的药物中的应用 |
| WO2021012176A1 (en) * | 2019-07-23 | 2021-01-28 | Shanghaitech University | Asic1 channel antagonist antibody |
| WO2021202807A1 (en) | 2020-03-31 | 2021-10-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Proteomic screening for lysosomal storage diseases |
| WO2021203031A2 (en) * | 2020-04-02 | 2021-10-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Antibodies that specifically bind peptides associated with the primary immunodeficiencies: wiskott-aldrich syndrome and x-linked agammaglobulinemia |
| CN114729014A (zh) | 2020-04-08 | 2022-07-08 | 纳诺皮技术有限公司 | 单克隆抗体及其用途 |
| WO2021207697A1 (en) | 2020-04-10 | 2021-10-14 | Cantex Pharmaceuticals, Inc. | Treatment of acute lung injury |
| WO2021207613A1 (en) * | 2020-04-10 | 2021-10-14 | 2Seventy Bio, Inc. | Frb antibodies |
| JP7525762B2 (ja) * | 2020-05-18 | 2024-07-31 | ビオシオン インコーポレイテッド | Ｉｌ６ｒに結合する抗体及びその使用 |
| AU2021274836A1 (en) | 2020-05-19 | 2023-01-05 | Aarhus Universitet | Lysm receptor motifs |
| US20240316008A1 (en) | 2020-06-22 | 2024-09-26 | Tranquis Therapeutics, Inc. | Treatment of systemic immune activation syndromes |
| AR122933A1 (es) | 2020-07-10 | 2022-10-19 | Novo Nordisk As | Métodos para tratar la enfermedad cardiovascular |
| WO2022040604A1 (en) | 2020-08-21 | 2022-02-24 | BioAge Labs, Inc. | Use of dp1 receptor antagonists for the treatment of viral respiratory tract infections and dysregulated immune response in aged and aging patients |
| US20230263827A1 (en) | 2020-09-02 | 2023-08-24 | Serhat Gumrukcu | Expanded memory subsets of gamma delta t cells for immunotherapy |
| WO2022130409A1 (en) * | 2020-12-18 | 2022-06-23 | Dr. Reddy's Laboratories Limited | Il-6r targeting compositions with reduced heterogeneity in functional attributes |
| WO2024126805A1 (en) | 2022-12-15 | 2024-06-20 | Aarhus Universitet | Synthetic activation of multimeric transmembrane receptors |
| CN118085075B (zh) * | 2023-11-29 | 2024-08-30 | 武汉爱博泰克生物科技有限公司 | 抗人甲胎蛋白的兔单克隆抗体及其应用 |
| CN121159693B (zh) * | 2025-08-19 | 2026-06-09 | 江苏阿塔斯生物科技有限公司 | 一种结合人cd8的单克隆抗体及其制备方法与应用 |
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-
2012
- 2012-02-28 CN CN201280021430.0A patent/CN103502274B/zh not_active Expired - Fee Related
- 2012-02-28 EP EP12752484.1A patent/EP2681243B1/en not_active Not-in-force
- 2012-02-28 AU AU2012223449A patent/AU2012223449A1/en not_active Abandoned
- 2012-02-28 MX MX2013009679A patent/MX342810B/es active IP Right Grant
- 2012-02-28 JP JP2013556805A patent/JP6097702B2/ja not_active Expired - Fee Related
- 2012-02-28 KR KR1020137026011A patent/KR20140043724A/ko not_active Withdrawn
- 2012-02-28 RU RU2013144392/10A patent/RU2013144392A/ru not_active Application Discontinuation
- 2012-02-28 WO PCT/US2012/026954 patent/WO2012118813A2/en not_active Ceased
- 2012-02-28 BR BR112013021863A patent/BR112013021863A2/pt not_active IP Right Cessation
- 2012-02-28 US US13/407,293 patent/US8753634B2/en not_active Expired - Fee Related
- 2012-02-28 CA CA2827581A patent/CA2827581A1/en not_active Abandoned
-
2013
- 2013-08-27 ZA ZA2013/06451A patent/ZA201306451B/en unknown
- 2013-09-03 IL IL228275A patent/IL228275A/en active IP Right Grant
-
2014
- 2014-05-02 US US14/268,932 patent/US9951136B2/en not_active Expired - Fee Related
-
2017
- 2017-04-16 IL IL251744A patent/IL251744A0/en unknown
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