CA2827581A1 - Anti-il-6 receptor antibodies and methods of use - Google Patents
Anti-il-6 receptor antibodies and methods of use Download PDFInfo
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- CA2827581A1 CA2827581A1 CA2827581A CA2827581A CA2827581A1 CA 2827581 A1 CA2827581 A1 CA 2827581A1 CA 2827581 A CA2827581 A CA 2827581A CA 2827581 A CA2827581 A CA 2827581A CA 2827581 A1 CA2827581 A1 CA 2827581A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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Applications Claiming Priority (3)
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| US201161449005P | 2011-03-03 | 2011-03-03 | |
| US61/449,005 | 2011-03-03 | ||
| PCT/US2012/026954 WO2012118813A2 (en) | 2011-03-03 | 2012-02-28 | Anti-il-6 receptor antibodies and methods of use |
Publications (1)
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| CA2827581A1 true CA2827581A1 (en) | 2012-09-07 |
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| CA2827581A Abandoned CA2827581A1 (en) | 2011-03-03 | 2012-02-28 | Anti-il-6 receptor antibodies and methods of use |
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| RU (1) | RU2013144392A (enExample) |
| WO (1) | WO2012118813A2 (enExample) |
| ZA (1) | ZA201306451B (enExample) |
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| CN102002104A (zh) | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
| RU2013144392A (ru) | 2011-03-03 | 2015-04-10 | Апексиджен, Инк. | Антитела к рецептору il-6 и способы применения |
| WO2014052462A2 (en) * | 2012-09-25 | 2014-04-03 | Cytomx Therapeutics, Inc. | Activatable antibodies that bind interleukin-6 receptor and methods of use thereof |
| CN105658237B (zh) | 2013-10-21 | 2021-03-09 | 基因泰克公司 | 抗Ly6E抗体及使用方法 |
| JP2016208934A (ja) * | 2015-05-12 | 2016-12-15 | 学校法人日本大学 | 抗イヌインターロイキン−６受容体モノクローナル抗体又は抗体フラグメント及びその利用 |
| EA201890185A1 (ru) | 2015-07-31 | 2018-07-31 | Медиммун Лимитед | Способы лечения опосредованных гепсидином нарушений |
| WO2017201731A1 (en) | 2016-05-27 | 2017-11-30 | Beijing Vdjbio Co., Ltd. | Antibodies, composition and kits comprising same, and methods of use thereof |
| WO2018022479A1 (en) | 2016-07-25 | 2018-02-01 | Biogen Ma Inc. | Anti-hspa5 (grp78) antibodies and uses thereof |
| RU2656160C2 (ru) * | 2016-08-17 | 2018-05-31 | Закрытое Акционерное Общество "Биокад" | Антитело или его антигенсвязывающий фрагмент, способный связываться с рецептором интерлейкина-6 человека |
| BR112019011186A2 (pt) | 2016-12-01 | 2019-10-08 | Regeneron Pharmaceuticals, Inc. | conjugado de anticorpo radiomarcado, composto, e, métodos de imageamento e para tratamento de um tumor. |
| CA3045310A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| WO2018112237A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor |
| CN117045784A (zh) | 2016-12-14 | 2023-11-14 | 比奥拉治疗股份有限公司 | 使用利用可摄入装置释放的il-12/il-23抑制剂治疗胃肠道疾病 |
| JP7630906B2 (ja) | 2017-02-01 | 2025-02-18 | イェール・ユニヴァーシティー | 利尿薬耐性の治療 |
| CA3054632A1 (en) | 2017-03-30 | 2018-10-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| WO2018234879A1 (en) | 2017-06-22 | 2018-12-27 | Novartis Ag | Il-1beta binding antibodies for use in treating cancer |
| WO2018237287A1 (en) * | 2017-06-22 | 2018-12-27 | Apexigen, Inc. | Anti-vista antibodies and methods of use |
| WO2018235056A1 (en) | 2017-06-22 | 2018-12-27 | Novartis Ag | Il-1beta binding antibodies for use in treating cancer |
| CN111051343B (zh) * | 2017-09-13 | 2022-11-22 | 江苏恒瑞医药股份有限公司 | Il-6r抗体、其抗原结合片段及医药用途 |
| MX2020006882A (es) | 2018-01-05 | 2020-09-07 | Novo Nordisk As | Metodos para tratar inflamacion mediada por interleucina-6 sin inmunosupresion. |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| EP3810268A1 (en) | 2018-06-20 | 2021-04-28 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
| WO2020072996A1 (en) | 2018-10-05 | 2020-04-09 | Seattle Children's Hospital (D/B/A Seattle Children's Research Institute) | Newborn screening for primary immunodeficiencies, cystinosis, and wilson disease |
| US20220025036A1 (en) | 2018-12-21 | 2022-01-27 | Novartis Ag | Use of il-1beta binding antibodies |
| AU2020259884A1 (en) * | 2019-04-17 | 2021-10-07 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination |
| CN110124029B (zh) * | 2019-04-19 | 2023-08-11 | 中山大学附属第六医院 | Il-6r抗体及羊水干细胞在制备用于治疗nec的药物中的应用 |
| EP4004038A4 (en) * | 2019-07-23 | 2023-07-26 | Shanghaitech University | Asic1 channel antagonist antibody |
| WO2021202807A1 (en) | 2020-03-31 | 2021-10-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Proteomic screening for lysosomal storage diseases |
| EP4126939A4 (en) * | 2020-04-02 | 2024-08-21 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | ANTIBODIES THAT BIND SPECIFICALLY TO PEPTIDES ASSOCIATED WITH PRIMARY IMMUNODEFICIENCIES: WISKOTT-ALDRICH SYNDROME AND X-LINKED AGAMMAGLOBULINEMIA |
| CN114729014A (zh) * | 2020-04-08 | 2022-07-08 | 纳诺皮技术有限公司 | 单克隆抗体及其用途 |
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- 2012-02-28 JP JP2013556805A patent/JP6097702B2/ja not_active Expired - Fee Related
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- 2012-02-28 MX MX2013009679A patent/MX342810B/es active IP Right Grant
- 2012-02-28 KR KR1020137026011A patent/KR20140043724A/ko not_active Withdrawn
- 2012-02-28 CN CN201280021430.0A patent/CN103502274B/zh not_active Expired - Fee Related
- 2012-02-28 WO PCT/US2012/026954 patent/WO2012118813A2/en not_active Ceased
- 2012-02-28 BR BR112013021863A patent/BR112013021863A2/pt not_active IP Right Cessation
- 2012-02-28 EP EP12752484.1A patent/EP2681243B1/en not_active Not-in-force
- 2012-02-28 CA CA2827581A patent/CA2827581A1/en not_active Abandoned
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| MX342810B (es) | 2016-10-13 |
| EP2681243A2 (en) | 2014-01-08 |
| US20140322239A1 (en) | 2014-10-30 |
| WO2012118813A3 (en) | 2012-11-08 |
| MX2013009679A (es) | 2014-05-13 |
| IL251744A0 (en) | 2017-06-29 |
| EP2681243A4 (en) | 2014-09-10 |
| US8753634B2 (en) | 2014-06-17 |
| WO2012118813A2 (en) | 2012-09-07 |
| JP6097702B2 (ja) | 2017-03-15 |
| US20120225060A1 (en) | 2012-09-06 |
| RU2013144392A (ru) | 2015-04-10 |
| CN103502274A (zh) | 2014-01-08 |
| ZA201306451B (en) | 2015-03-25 |
| BR112013021863A2 (pt) | 2016-11-22 |
| EP2681243B1 (en) | 2018-09-05 |
| AU2012223449A1 (en) | 2013-05-02 |
| JP2014509510A (ja) | 2014-04-21 |
| CN103502274B (zh) | 2016-01-06 |
| KR20140043724A (ko) | 2014-04-10 |
| IL228275A (en) | 2017-04-30 |
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