|
US4903164A
(en)
|
1988-12-08 |
1990-02-20 |
Texas Instruments Incorporated |
O-ring/back-up ring seal for high pressure transducers
|
|
JP2000516743A
(ja)
*
|
1996-09-04 |
2000-12-12 |
インタートラスト テクノロージーズ コーポレイション |
信用インフラストラクチャストラクチャ支援システム、安全な電子交易、電子商取引、交易プロセス制御及び自動化のための方法及び技術、分散コンピューテーション及び権利管理
|
|
EP2081905B1
(en)
|
2006-07-28 |
2012-09-12 |
Boehringer Ingelheim International GmbH |
Sulfonyl compounds which modulate the cb2 receptor
|
|
AU2007287428B2
(en)
|
2006-08-24 |
2011-08-11 |
Astrazeneca Ab |
Morpholino pyrimidine derivatives useful in the treatment of proliferative disorders
|
|
MX2009002888A
(es)
|
2006-09-25 |
2009-03-31 |
Boehringer Ingelheim Int |
Compuestos que modulan el receptor cb2.
|
|
ES2449482T3
(es)
*
|
2007-01-09 |
2014-03-19 |
Amgen Inc. |
Derivados de bis-aril-amida útiles para el tratamiento de cáncer
|
|
US8173647B2
(en)
*
|
2007-02-06 |
2012-05-08 |
Gordana Atallah |
PI 3-kinase inhibitors and methods of their use
|
|
EA201000092A1
(ru)
*
|
2007-07-09 |
2010-06-30 |
Астразенека Аб |
Тризамещенные пиримидиновые производные для лечения пролиферативных заболеваний
|
|
CA2692720A1
(en)
*
|
2007-07-09 |
2009-01-15 |
Astrazeneca Ab |
Morpholino pyrimidine derivatives used in diseases linked to mtor kinase and/or pi3k
|
|
WO2009061652A1
(en)
|
2007-11-07 |
2009-05-14 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
|
US9029411B2
(en)
|
2008-01-25 |
2015-05-12 |
Millennium Pharmaceuticals, Inc. |
Thiophenes and uses thereof
|
|
JP5539235B2
(ja)
|
2008-02-29 |
2014-07-02 |
エボテック・アーゲー |
アミド化合物、組成物およびそれらの使用
|
|
US20120015988A1
(en)
*
|
2008-05-13 |
2012-01-19 |
Boehringer Ingelheim International Gmbh |
Sulfone Compounds Which Modulate The CB2 Receptor
|
|
KR101331341B1
(ko)
|
2008-05-23 |
2013-11-19 |
와이어쓰 엘엘씨 |
Pi3 키나제 및 mtor 억제제로서의 트리아진 화합물
|
|
KR20110018451A
(ko)
*
|
2008-06-19 |
2011-02-23 |
밀레니엄 파머슈티컬스 인코퍼레이티드 |
티오펜 또는 티아졸 유도체, 그리고 pi3k 저해물질로서 이들의 용도
|
|
EP2326629B1
(en)
|
2008-07-10 |
2013-10-02 |
Boehringer Ingelheim International GmbH |
Sulfone compounds which modulate the cb2 receptor
|
|
CA2729045A1
(en)
|
2008-07-31 |
2010-02-04 |
Philippe Bergeron |
Pyrimidine compounds, compositions and methods of use
|
|
WO2010030027A1
(en)
|
2008-09-10 |
2010-03-18 |
Mitsubishi Tanabe Pharma Corporation |
Aromatic nitrogen-containing 6-membered ring compounds and their use
|
|
WO2010033168A2
(en)
*
|
2008-09-18 |
2010-03-25 |
Renovis, Inc. |
Amide compounds, compositions and uses thereof
|
|
NZ591111A
(en)
|
2008-09-25 |
2013-08-30 |
Boehringer Ingelheim Int |
Sulfonyl compounds which selectively modulate the cb2 receptor
|
|
TWI378933B
(en)
|
2008-10-14 |
2012-12-11 |
Daiichi Sankyo Co Ltd |
Morpholinopurine derivatives
|
|
US20110053923A1
(en)
|
2008-12-22 |
2011-03-03 |
Astrazeneca |
Chemical compounds 610
|
|
EP2391619A1
(en)
|
2009-01-30 |
2011-12-07 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and their use as pi3k inhibitors
|
|
US8796314B2
(en)
|
2009-01-30 |
2014-08-05 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
US9090601B2
(en)
|
2009-01-30 |
2015-07-28 |
Millennium Pharmaceuticals, Inc. |
Thiazole derivatives
|
|
EP2406258B1
(en)
|
2009-03-13 |
2014-12-03 |
Cellzome Limited |
PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
|
|
US8835429B2
(en)
*
|
2009-04-17 |
2014-09-16 |
Wyeth Llc |
Pyrimidine compounds, their use as mTOR kinase and Pl3 kinase inhibitors, and their syntheses
|
|
WO2010120991A1
(en)
*
|
2009-04-17 |
2010-10-21 |
Wyeth Llc |
5, 6, 7, 8-tetrahydropyrido[4,3-d]pyrimidine compounds, their use as mtor, pi3, and hsmg-1 kinase inhibitors, and their syntheses
|
|
WO2010120996A1
(en)
*
|
2009-04-17 |
2010-10-21 |
Wyeth Llc |
5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine compounds, their use as mtor kinase and pi3 kinase inhibitors, and their syntheses
|
|
JPWO2010125799A1
(ja)
*
|
2009-04-27 |
2012-10-25 |
塩野義製薬株式会社 |
Pi3k阻害活性を有するウレア誘導体
|
|
US8299103B2
(en)
|
2009-06-15 |
2012-10-30 |
Boehringer Ingelheim International Gmbh |
Compounds which selectively modulate the CB2 receptor
|
|
US8383615B2
(en)
|
2009-06-16 |
2013-02-26 |
Boehringer Ingelheim International Gmbh |
Azetidine 2-carboxamide derivatives which modulate the CB2 receptor
|
|
GEP20207129B
(en)
*
|
2009-06-17 |
2020-07-10 |
Vertex Pharma |
Inhibitors of influenza viruses replication
|
|
US20100331305A1
(en)
*
|
2009-06-24 |
2010-12-30 |
Genentech, Inc. |
Oxo-heterocycle fused pyrimidine compounds, compositions and methods of use
|
|
EP2480544A1
(en)
|
2009-09-22 |
2012-08-01 |
Boehringer Ingelheim International GmbH |
Compounds which selectively modulate the cb2 receptor
|
|
EA201290255A1
(ru)
|
2009-10-30 |
2013-04-30 |
Ариад Фармасьютикалз, Инк. |
Способы и композиции для лечения рака
|
|
CN102711766B
(zh)
|
2009-11-12 |
2014-06-04 |
霍夫曼-拉罗奇有限公司 |
N-9-取代的嘌呤化合物、组合物和使用方法
|
|
MX2012005225A
(es)
|
2009-11-12 |
2012-07-25 |
Hoffmann La Roche |
Compuestos y composiciones de purina n-7 sustituida y pirazolopirimidina, y metodos de uso.
|
|
US9315491B2
(en)
|
2009-12-28 |
2016-04-19 |
Development Center For Biotechnology |
Pyrimidine compounds as mTOR and PI3K inhibitors
|
|
EP2523936A1
(en)
|
2010-01-15 |
2012-11-21 |
Boehringer Ingelheim International GmbH |
Compounds which modulate the cb2 receptor
|
|
US9249129B2
(en)
|
2010-03-04 |
2016-02-02 |
Cellzome Limited |
Morpholino substituted urea derivatives as mTOR inhibitors
|
|
WO2011109324A1
(en)
|
2010-03-05 |
2011-09-09 |
Boehringer Ingelheim International Gmbh |
Tetrazole compounds which selectively modulate the cb2 receptor
|
|
SA111320519B1
(ar)
|
2010-06-11 |
2014-07-02 |
Astrazeneca Ab |
مركبات بيريميدينيل للاستخدام كمثبطات atr
|
|
JP5746764B2
(ja)
|
2010-07-22 |
2015-07-08 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を調節する化合物
|
|
US8859768B2
(en)
|
2010-08-11 |
2014-10-14 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
SG10201506238SA
(en)
|
2010-08-11 |
2015-09-29 |
Millennium Pharm Inc |
Heteroaryls And Uses Thereof
|
|
US9062038B2
(en)
|
2010-08-11 |
2015-06-23 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
CN104945373A
(zh)
|
2010-10-01 |
2015-09-30 |
诺华有限公司 |
制造嘧啶衍生物的方法
|
|
PE20141044A1
(es)
|
2010-10-13 |
2014-09-07 |
Millennium Pharm Inc |
Heteroarilos y sus usos
|
|
WO2012058671A1
(en)
|
2010-10-31 |
2012-05-03 |
Endo Pharmaceuticals Inc. |
Substituted quinazoline and pyrido-pyrimidine derivatives
|
|
US20140163023A1
(en)
|
2011-04-04 |
2014-06-12 |
Cellzome Limited |
Dihydropyrrolo pyrimidine derivatives as mtor inhibitors
|
|
CN102887867B
(zh)
*
|
2011-07-21 |
2015-04-15 |
中国科学院上海药物研究所 |
一类三嗪类化合物、该化合物的制备方法及其用途
|
|
CN103842357A
(zh)
*
|
2011-07-26 |
2014-06-04 |
格吕伦塔尔有限公司 |
作为类香草素受体配体的被取代的、含有杂芳环吡唑的羧酰胺和脲衍生物
|
|
UA118010C2
(uk)
|
2011-08-01 |
2018-11-12 |
Вертекс Фармасьютікалз Інкорпорейтед |
Інгібітори реплікації вірусів грипу
|
|
PT2753606T
(pt)
*
|
2011-09-02 |
2017-10-02 |
Purdue Pharma Lp |
Pirimidinas como bloqueadoras dos canais de sódio
|
|
KR20140070616A
(ko)
|
2011-09-21 |
2014-06-10 |
셀좀 리미티드 |
Mtor 저해제로서의 모르폴리노 치환된 우레아 또는 카바메이트 유도체
|
|
US9242993B2
(en)
|
2011-10-07 |
2016-01-26 |
Cellzome Limited |
Morpholino substituted bicyclic pyrimidine urea or carbamate derivatives as mTOR inhibitors
|
|
KR20160027219A
(ko)
|
2012-05-23 |
2016-03-09 |
에프. 호프만-라 로슈 아게 |
내배엽 및 간세포를 수득하고 사용하는 조성물 및 방법
|
|
EP2803668A1
(en)
|
2013-05-17 |
2014-11-19 |
Boehringer Ingelheim International Gmbh |
Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles
|
|
US9296727B2
(en)
|
2013-10-07 |
2016-03-29 |
Vertex Pharmaceuticals Incorporated |
Methods of regioselective synthesis of 2,4-disubstituted pyrimidines
|
|
HRP20191525T1
(hr)
|
2013-11-13 |
2019-11-29 |
Vertex Pharma |
Inhibitori replikacije virusa influence
|
|
EP3421468B1
(en)
|
2013-11-13 |
2020-11-04 |
Vertex Pharmaceuticals Incorporated |
Methods of preparing inhibitors of influenza viruses replication
|
|
CN106458921B
(zh)
*
|
2014-05-21 |
2020-03-24 |
阿勒根公司 |
作为甲酰肽受体调节剂的咪唑衍生物
|
|
SG11201700777VA
(en)
|
2014-08-04 |
2017-02-27 |
Nuevolution As |
Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
|
|
JP6704416B2
(ja)
|
2015-05-13 |
2020-06-03 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
インフルエンザウイルスの複製の阻害剤を調製する方法
|
|
WO2016183120A1
(en)
|
2015-05-13 |
2016-11-17 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of influenza viruses replication
|
|
TW201813963A
(zh)
|
2016-09-23 |
2018-04-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
TW201825465A
(zh)
|
2016-09-23 |
2018-07-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
TW201815787A
(zh)
|
2016-09-23 |
2018-05-01 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
US10421765B2
(en)
|
2017-05-26 |
2019-09-24 |
Board Of Regents, The University Of Texas System |
Tetrahydropyrido[4,3-d]pyrimidine inhibitors of ATR kinase
|
|
EP3651768B1
(en)
|
2017-07-13 |
2023-12-20 |
Board of Regents, The University of Texas System |
Heterocyclic inhibitors of atr kinase
|
|
EP3668839B1
(en)
|
2017-08-17 |
2023-04-12 |
Board of Regents, The University of Texas System |
Heterocyclic inhibitors of atr kinase
|
|
US10894052B2
(en)
|
2018-03-16 |
2021-01-19 |
Board Of Regents, The University Of Texas System |
Heterocyclic inhibitors of ATR kinase
|
|
TWI872177B
(zh)
|
2019-12-20 |
2025-02-11 |
丹麥商紐韋盧森公司 |
對核受體具有活性之化合物
|
|
US11447479B2
(en)
|
2019-12-20 |
2022-09-20 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
JP7713953B2
(ja)
|
2020-03-31 |
2025-07-28 |
ヌエヴォリューション・アクティーゼルスカブ |
核内受容体に対して活性な化合物
|
|
CA3174176A1
(en)
|
2020-03-31 |
2021-10-07 |
Sanne Schroder Glad |
Compounds active towards nuclear receptors
|