JP2009520682A5 - - Google Patents
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- Publication number
- JP2009520682A5 JP2009520682A5 JP2008529406A JP2008529406A JP2009520682A5 JP 2009520682 A5 JP2009520682 A5 JP 2009520682A5 JP 2008529406 A JP2008529406 A JP 2008529406A JP 2008529406 A JP2008529406 A JP 2008529406A JP 2009520682 A5 JP2009520682 A5 JP 2009520682A5
- Authority
- JP
- Japan
- Prior art keywords
- tyr
- compound
- azagly
- asn
- trp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005370388 | 2005-12-22 | ||
| JP2006275843 | 2006-10-06 | ||
| PCT/JP2006/326176 WO2007072997A1 (en) | 2005-12-22 | 2006-12-21 | Metastin derivatives and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010182482A Division JP5298087B2 (ja) | 2005-12-22 | 2010-08-17 | メタスチン誘導体およびその用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009520682A JP2009520682A (ja) | 2009-05-28 |
| JP2009520682A5 true JP2009520682A5 (OSRAM) | 2010-10-07 |
| JP4653840B2 JP4653840B2 (ja) | 2011-03-16 |
Family
ID=37846230
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008529406A Expired - Fee Related JP4653840B2 (ja) | 2005-12-22 | 2006-12-21 | メタスチン誘導体およびその用途 |
| JP2010182482A Active JP5298087B2 (ja) | 2005-12-22 | 2010-08-17 | メタスチン誘導体およびその用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010182482A Active JP5298087B2 (ja) | 2005-12-22 | 2010-08-17 | メタスチン誘導体およびその用途 |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US7960348B2 (OSRAM) |
| EP (1) | EP1963362B1 (OSRAM) |
| JP (2) | JP4653840B2 (OSRAM) |
| KR (1) | KR101368607B1 (OSRAM) |
| AR (1) | AR058584A1 (OSRAM) |
| AU (1) | AU2006328333B2 (OSRAM) |
| BR (1) | BRPI0619399B8 (OSRAM) |
| CA (1) | CA2634647C (OSRAM) |
| CR (1) | CR10019A (OSRAM) |
| CY (1) | CY1112353T1 (OSRAM) |
| DK (1) | DK1963362T3 (OSRAM) |
| ES (1) | ES2375038T3 (OSRAM) |
| GE (1) | GEP20115356B (OSRAM) |
| HR (1) | HRP20110851T1 (OSRAM) |
| IL (1) | IL190888A (OSRAM) |
| JO (1) | JO2799B1 (OSRAM) |
| MA (1) | MA30060B1 (OSRAM) |
| ME (1) | ME01015B (OSRAM) |
| MY (1) | MY151967A (OSRAM) |
| NO (1) | NO341879B1 (OSRAM) |
| NZ (1) | NZ568322A (OSRAM) |
| PE (1) | PE20071141A1 (OSRAM) |
| PL (1) | PL1963362T3 (OSRAM) |
| PT (1) | PT1963362E (OSRAM) |
| RS (1) | RS52007B (OSRAM) |
| RU (1) | RU2430107C2 (OSRAM) |
| SI (1) | SI1963362T1 (OSRAM) |
| TW (1) | TWI386417B (OSRAM) |
| WO (1) | WO2007072997A1 (OSRAM) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003292696A1 (en) | 2002-12-26 | 2004-08-10 | Takeda Pharmaceutical Company Limited | Metastin derivative and use thereof |
| WO2004080479A1 (ja) | 2003-03-12 | 2004-09-23 | Takeda Pharmaceutical Company Limited | 性腺機能改善剤 |
| CN101845091A (zh) * | 2004-06-25 | 2010-09-29 | 武田药品工业株式会社 | 转移素衍生物及其用途 |
| TWI386417B (zh) | 2005-12-22 | 2013-02-21 | Takeda Pharmaceutical | 轉移抑素衍生物及其用途 |
| US20090093615A1 (en) * | 2005-12-22 | 2009-04-09 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| US8404643B2 (en) * | 2005-12-22 | 2013-03-26 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| JO3048B1 (ar) | 2006-10-25 | 2016-09-05 | Takeda Pharmaceuticals Co | مشتقات متاستين واستخدامها |
| WO2009131191A1 (ja) | 2008-04-24 | 2009-10-29 | 武田薬品工業株式会社 | メタスチン誘導体およびその用途 |
| DK2314609T3 (en) * | 2008-07-30 | 2017-03-13 | Takeda Pharmaceuticals Co | METASTIN DERIVATIVES AND USE THEREOF |
| MX2011006170A (es) * | 2008-12-29 | 2011-06-27 | Takeda Pharmaceutical | Agente preventivo/terapeutico contra el cancer. |
| AU2010336168A1 (en) * | 2009-12-22 | 2012-06-14 | Takeda Pharmaceutical Company Limited | Sustained-release formulation |
| PE20130276A1 (es) | 2010-06-25 | 2013-03-20 | Takeda Pharmaceutical | Formulacion de liberacion sostenida |
| EP2755690B1 (en) | 2011-08-04 | 2020-04-01 | Merck Sharp & Dohme B.V. | Kisspeptide-pentasaccharide conjugates |
| US9517210B2 (en) | 2012-07-12 | 2016-12-13 | Takeda Pharmaceutical Company Limited | Method for producing microcapsule powder |
| WO2015112703A1 (en) * | 2014-01-22 | 2015-07-30 | The Johns Hopkins University | Compositions and methods for treating diabetes |
| JP6253146B2 (ja) * | 2014-02-04 | 2017-12-27 | 国立大学法人山口大学 | 新規なペプチド誘導体及びこれを含有する医薬 |
| BR112019006227A2 (pt) | 2016-09-30 | 2019-06-18 | Myovant Sciences Gmbh | métodos de tratamento de leiomioma uterino e endometriose |
| EP3518952A1 (en) * | 2016-09-30 | 2019-08-07 | Myovant Sciences GmbH | Methods of treating female infertility |
| CN116813705A (zh) * | 2017-07-05 | 2023-09-29 | 凯惠科技发展(上海)有限公司 | 一种肽类化合物、其应用及含其的组合物 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL74827A (en) | 1984-05-21 | 1989-06-30 | Salk Inst For Biological Studi | Peptides active as gnrh antagonists and pharmaceutical compositions containing them |
| MX9100717A (es) | 1990-08-24 | 1992-04-01 | Syntex Inc | Antagonistas de la bradiquinina |
| AU7333496A (en) | 1995-10-19 | 1997-05-07 | Takeda Chemical Industries Ltd. | Quinoline derivatives as gnrh antagonists |
| JPH09169735A (ja) | 1995-10-19 | 1997-06-30 | Takeda Chem Ind Ltd | キノリン誘導体、その製造法および用途 |
| JP2000510453A (ja) | 1996-04-19 | 2000-08-15 | ノボ ノルディスク アクティーゼルスカブ | 成長ホルモン遊離特性を有する化合物 |
| CA2283299A1 (en) | 1997-03-07 | 1998-09-11 | Human Genome Sciences, Inc. | 186 human secreted proteins |
| JP4486187B2 (ja) | 1998-10-27 | 2010-06-23 | 武田薬品工業株式会社 | 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド |
| US6528054B1 (en) | 1998-12-28 | 2003-03-04 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| HK1047045A1 (zh) | 1999-06-28 | 2003-02-07 | Abbott Gmbh & Co. Kg | 預防腫瘤生長的方法 |
| CA2380613C (en) | 1999-08-02 | 2014-03-25 | Archer-Daniels-Midland Company | Production of l-lysine by corynebacterium strain having mutation in ilvbn operon |
| US6838259B2 (en) | 1999-12-17 | 2005-01-04 | Takeda Chemical Industries, Ltd. | Process for producing kiss-1 peptide |
| CA2404233A1 (en) | 2000-03-29 | 2001-10-04 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| AU2001244609A1 (en) | 2000-03-30 | 2001-10-15 | Takeda Chemical Industries Ltd. | Novel protein, dna thereof and process for producing the same |
| US7834141B1 (en) | 2000-03-31 | 2010-11-16 | Theresa Siler-Khodr | Non-mammalian GnRH analogs and uses thereof in tumor cell growth regulation and cancer therapy |
| RU2311920C2 (ru) | 2000-09-20 | 2007-12-10 | Корикса Корпорейшн | Композиции и способы для лечения и диагностики рака легких |
| JP2003026601A (ja) | 2000-11-29 | 2003-01-29 | Takeda Chem Ind Ltd | 医薬組成物およびその製造法 |
| JP2002320496A (ja) | 2001-02-26 | 2002-11-05 | Takeda Chem Ind Ltd | 新規マウス型ＫｉＳＳ−１レセプタータンパク質およびそのＤＮＡ |
| WO2002085399A1 (fr) | 2001-04-20 | 2002-10-31 | Takeda Chemical Industries, Ltd. | Preparations contenant un peptide |
| CN1509336A (zh) | 2001-05-17 | 2004-06-30 | 株式会社岛津制作所 | 肽的制备方法 |
| WO2003027149A1 (fr) | 2001-09-19 | 2003-04-03 | Takeda Chemical Industries, Ltd. | Anticorps et utilisation de ce dernier |
| US20050176091A1 (en) | 2002-01-11 | 2005-08-11 | Takao Yamada | Process for producing kiss-1 peptide |
| JP2003300906A (ja) | 2002-04-12 | 2003-10-21 | Daiichi Fine Chemical Co Ltd | がん転移抑制因子の安定化 |
| WO2004038021A1 (en) | 2002-10-25 | 2004-05-06 | Paradigm Therapeutics Limited | Gpr54 knock-out mammals and screening methods using them |
| AU2003292696A1 (en) * | 2002-12-26 | 2004-08-10 | Takeda Pharmaceutical Company Limited | Metastin derivative and use thereof |
| JP4804714B2 (ja) | 2002-12-26 | 2011-11-02 | 武田薬品工業株式会社 | メタスチン誘導体およびその用途 |
| US6800611B2 (en) * | 2003-01-06 | 2004-10-05 | Takeda Chemical Industries, Ltd. | Metastin derivatives and their use |
| KR100595364B1 (ko) | 2003-02-20 | 2006-07-03 | 재단법인 목암생명공학연구소 | Ｌｋ8 단백질을 유효성분으로 포함하는 항암제 |
| WO2004080479A1 (ja) | 2003-03-12 | 2004-09-23 | Takeda Pharmaceutical Company Limited | 性腺機能改善剤 |
| EP1464652A1 (en) | 2003-04-02 | 2004-10-06 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases |
| US20050002935A1 (en) | 2003-04-17 | 2005-01-06 | Vincent Ling | Use of B7-H3 as an immunoregulatory agent |
| US20050026224A1 (en) | 2003-04-28 | 2005-02-03 | Follettie Maximillian T. | Methods and compositions for modulating G-protein coupled receptor 54 |
| WO2004101747A2 (en) | 2003-05-07 | 2004-11-25 | The General Hospital Corporation | Identification and use of gpr54 and its ligands for reproductive disorders and contraception |
| DK1633702T3 (da) * | 2003-05-30 | 2008-11-10 | Prozymex As | Proteaseinhibitorer |
| JP4688678B2 (ja) | 2003-11-03 | 2011-05-25 | 北京沙東生物技術有限公司 | 抗癌作用を有する組換えタンパク質、それをコードする遺伝子、及びそれらの使用 |
| RU2333221C2 (ru) | 2003-11-03 | 2008-09-10 | Бейцзин Санбио Байотек Ко., Лтд. | Рекомбинантный белок, обладающий противораковым действием, кодирующий его ген и его применение |
| WO2005095973A2 (en) | 2004-03-25 | 2005-10-13 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 54 (gpr54) |
| CN101845091A (zh) | 2004-06-25 | 2010-09-29 | 武田药品工业株式会社 | 转移素衍生物及其用途 |
| US7725869B1 (en) | 2005-04-07 | 2010-05-25 | Xilinx, Inc. | Method and apparatus for modeling multiple instances of an electronic circuit using an imperative programming language description |
| WO2007084211A2 (en) | 2005-11-11 | 2007-07-26 | The General Hospital Corporation | Use of gpr54 ligands for treatment of reproductive disorders, proliferative disorders, and for contraception |
| US20090099334A1 (en) | 2005-12-22 | 2009-04-16 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| US20090093615A1 (en) | 2005-12-22 | 2009-04-09 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| US8404643B2 (en) | 2005-12-22 | 2013-03-26 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| TWI386417B (zh) | 2005-12-22 | 2013-02-21 | Takeda Pharmaceutical | 轉移抑素衍生物及其用途 |
| JO3048B1 (ar) | 2006-10-25 | 2016-09-05 | Takeda Pharmaceuticals Co | مشتقات متاستين واستخدامها |
-
2006
- 2006-12-20 TW TW095147852A patent/TWI386417B/zh active
- 2006-12-20 AR ARP060105651A patent/AR058584A1/es active IP Right Grant
- 2006-12-21 ME MEP-2009-175A patent/ME01015B/me unknown
- 2006-12-21 KR KR1020087012506A patent/KR101368607B1/ko active Active
- 2006-12-21 JP JP2008529406A patent/JP4653840B2/ja not_active Expired - Fee Related
- 2006-12-21 PT PT06843555T patent/PT1963362E/pt unknown
- 2006-12-21 PE PE2006001686A patent/PE20071141A1/es active IP Right Grant
- 2006-12-21 WO PCT/JP2006/326176 patent/WO2007072997A1/en not_active Ceased
- 2006-12-21 RS RS20110437A patent/RS52007B/sr unknown
- 2006-12-21 PL PL06843555T patent/PL1963362T3/pl unknown
- 2006-12-21 EP EP06843555A patent/EP1963362B1/en active Active
- 2006-12-21 HR HR20110851T patent/HRP20110851T1/hr unknown
- 2006-12-21 SI SI200631152T patent/SI1963362T1/sl unknown
- 2006-12-21 GE GEAP200610770A patent/GEP20115356B/en unknown
- 2006-12-21 BR BRPI0619399A patent/BRPI0619399B8/pt not_active IP Right Cessation
- 2006-12-21 JO JO2006486A patent/JO2799B1/en active
- 2006-12-21 RU RU2008125063/04A patent/RU2430107C2/ru active
- 2006-12-21 DK DK06843555.1T patent/DK1963362T3/da active
- 2006-12-21 US US12/158,251 patent/US7960348B2/en active Active
- 2006-12-21 MY MYPI20082169 patent/MY151967A/en unknown
- 2006-12-21 NZ NZ568322A patent/NZ568322A/en unknown
- 2006-12-21 ES ES06843555T patent/ES2375038T3/es active Active
- 2006-12-21 CA CA2634647A patent/CA2634647C/en active Active
- 2006-12-21 AU AU2006328333A patent/AU2006328333B2/en not_active Ceased
-
2008
- 2008-04-15 IL IL190888A patent/IL190888A/en active IP Right Grant
- 2008-05-26 CR CR10019A patent/CR10019A/es unknown
- 2008-06-10 NO NO20082595A patent/NO341879B1/no unknown
- 2008-06-18 MA MA31044A patent/MA30060B1/fr unknown
-
2010
- 2010-08-17 JP JP2010182482A patent/JP5298087B2/ja active Active
-
2011
- 2011-11-18 CY CY20111101116T patent/CY1112353T1/el unknown
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