ATE506362T1 - 1-aza-bicycloä3.3.1ünonane - Google Patents

1-aza-bicycloä3.3.1ünonane

Info

Publication number
ATE506362T1
ATE506362T1 AT05771214T AT05771214T ATE506362T1 AT E506362 T1 ATE506362 T1 AT E506362T1 AT 05771214 T AT05771214 T AT 05771214T AT 05771214 T AT05771214 T AT 05771214T AT E506362 T1 ATE506362 T1 AT E506362T1
Authority
AT
Austria
Prior art keywords
aza
Prior art date
Application number
AT05771214T
Other languages
English (en)
Inventor
Dominik Feuerbach
Werner Mueller
Bernard Roy
Thomas Troxler
Konstanze Hurth
Mathias Frederiksen
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE506362T1 publication Critical patent/ATE506362T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
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    • A61P25/32—Alcohol-abuse
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05771214T 2004-06-18 2005-06-17 1-aza-bicycloä3.3.1ünonane ATE506362T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58102004P 2004-06-18 2004-06-18
PCT/EP2005/006566 WO2005123732A1 (en) 2004-06-18 2005-06-17 1-aza-bicyclo[3.3.1]nonanes

Publications (1)

Publication Number Publication Date
ATE506362T1 true ATE506362T1 (de) 2011-05-15

Family

ID=35045272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05771214T ATE506362T1 (de) 2004-06-18 2005-06-17 1-aza-bicycloä3.3.1ünonane

Country Status (32)

Country Link
US (3) US20070249657A1 (de)
EP (2) EP2336129A1 (de)
JP (1) JP4944772B2 (de)
KR (3) KR101343654B1 (de)
CN (1) CN1964968A (de)
AR (1) AR049401A1 (de)
AT (1) ATE506362T1 (de)
AU (1) AU2005254689B2 (de)
BR (1) BRPI0510940A (de)
CA (1) CA2566155C (de)
CY (1) CY1111528T1 (de)
DE (1) DE602005027567D1 (de)
DK (1) DK1761533T3 (de)
EC (1) ECSP067053A (de)
ES (1) ES2364971T3 (de)
HR (1) HRP20110535T1 (de)
IL (2) IL179611A (de)
MA (1) MA28684B1 (de)
MX (1) MXPA06014697A (de)
MY (1) MY147262A (de)
NO (1) NO20070339L (de)
NZ (1) NZ551198A (de)
PE (1) PE20060437A1 (de)
PL (1) PL1761533T3 (de)
PT (1) PT1761533E (de)
RU (1) RU2445313C2 (de)
SG (1) SG153834A1 (de)
SI (1) SI1761533T1 (de)
TN (1) TNSN06407A1 (de)
TW (1) TWI370128B (de)
WO (1) WO2005123732A1 (de)
ZA (1) ZA200609255B (de)

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PE20060437A1 (es) 2004-06-18 2006-06-08 Novartis Ag COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525673D0 (en) * 2005-12-16 2006-01-25 Novartis Ag Organic compounds
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JO3250B1 (ar) 2009-09-22 2018-09-16 Novartis Ag إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7
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MX2013008704A (es) * 2011-01-27 2013-08-21 Novartis Ag Uso de activadores del receptor de acetil-colina nicotinico alfa-7.
MX2013010698A (es) 2011-03-18 2014-02-17 Novartis Ag Combinaciones de activadores del receptor de acetil-colina nicotinico alfa-7 y antagonistas del receptor de glutamato metabotropico 5 (mglur5) para usarse en la discinesia inducida por dopamina en la enfermedad de parkinson.
CA2852268C (en) 2011-10-20 2020-08-25 Novartis Ag Biomarkers predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
EP3461481A1 (de) * 2012-05-08 2019-04-03 Forum Pharmaceuticals Inc. Verfahren zur aufrechterhaltung, behandlung oder verbesserung der kognitiven funktion
AU2013337297A1 (en) * 2012-11-05 2015-05-21 Nantbio, Inc. Substituted indol-5-ol derivatives and their therapeutical applications
CA2894384C (en) 2012-12-11 2018-03-06 Novartis Ag Biomarker predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
ES2865736T3 (es) * 2013-01-15 2021-10-15 Novartis Ag Uso de agonistas del receptor de acetilcolina nicotínico alfa 7
JP6338223B2 (ja) * 2013-01-15 2018-06-06 ノバルティス アーゲー アルファ７ニコチン性アセチルコリン受容体アゴニストの使用
KR101879921B1 (ko) * 2013-01-15 2018-07-18 노파르티스 아게 기면증의 치료를 위한 알파 7 니코틴성 아세틸콜린 수용체 작용물질의 용도
US20150313884A1 (en) 2013-01-15 2015-11-05 Novartis Ag Use of alpha 7 nicotinic acetylcholine receptor agonists
RU2020105929A (ru) 2017-08-04 2021-09-06 Скайхоук Терапьютикс, Инк. Способы и композиции для модулирования сплайсинга
EP3920926A4 (de) 2019-02-05 2022-10-19 Skyhawk Therapeutics, Inc. Verfahren und zusammensetzungen zur modulierung der spleissung
JP7603592B2 (ja) 2019-02-05 2024-12-20 スカイホーク・セラピューティクス・インコーポレーテッド スプライシングを調節するための方法および組成物
WO2020163544A1 (en) 2019-02-06 2020-08-13 Skyhawk Therapeutics, Inc. Methods and compositions for modulating splicing
CN119638696A (zh) 2019-02-06 2025-03-18 斯基霍克疗法公司 用于调节剪接的方法和组合物

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PE20060437A1 (es) 2006-06-08
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AR049401A1 (es) 2006-07-26
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ZA200609255B (en) 2008-07-30
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US20070249657A1 (en) 2007-10-25
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