JP2009530612A5 - - Google Patents
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- Publication number
- JP2009530612A5 JP2009530612A5 JP2009500462A JP2009500462A JP2009530612A5 JP 2009530612 A5 JP2009530612 A5 JP 2009530612A5 JP 2009500462 A JP2009500462 A JP 2009500462A JP 2009500462 A JP2009500462 A JP 2009500462A JP 2009530612 A5 JP2009530612 A5 JP 2009530612A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- gelsolin
- risk
- level
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004878 Gelsolin Human genes 0.000 claims 20
- 108090001064 Gelsolin Proteins 0.000 claims 20
- 208000027866 inflammatory disease Diseases 0.000 claims 14
- 238000000034 method Methods 0.000 claims 8
- 238000002560 therapeutic procedure Methods 0.000 claims 7
- 210000001124 body fluid Anatomy 0.000 claims 5
- 239000010839 body fluid Substances 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 206010061218 Inflammation Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78250806P | 2006-03-15 | 2006-03-15 | |
| US60/782,508 | 2006-03-15 | ||
| PCT/US2007/006451 WO2007109056A2 (en) | 2006-03-15 | 2007-03-15 | Use of gelsolin to diagnose and treat inflammatory diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011270249A Division JP2012083359A (ja) | 2006-03-15 | 2011-12-09 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009530612A JP2009530612A (ja) | 2009-08-27 |
| JP2009530612A5 true JP2009530612A5 (enExample) | 2011-04-14 |
| JP5322917B2 JP5322917B2 (ja) | 2013-10-23 |
Family
ID=38522935
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009500462A Active JP5322917B2 (ja) | 2006-03-15 | 2007-03-15 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
| JP2011270249A Withdrawn JP2012083359A (ja) | 2006-03-15 | 2011-12-09 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
| JP2014071355A Withdrawn JP2014122924A (ja) | 2006-03-15 | 2014-03-31 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
| JP2015137491A Active JP6198777B2 (ja) | 2006-03-15 | 2015-07-09 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
| JP2017098198A Active JP6568144B2 (ja) | 2006-03-15 | 2017-05-17 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011270249A Withdrawn JP2012083359A (ja) | 2006-03-15 | 2011-12-09 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
| JP2014071355A Withdrawn JP2014122924A (ja) | 2006-03-15 | 2014-03-31 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
| JP2015137491A Active JP6198777B2 (ja) | 2006-03-15 | 2015-07-09 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
| JP2017098198A Active JP6568144B2 (ja) | 2006-03-15 | 2017-05-17 | 炎症性疾患の診断および処置のためのゲルゾリンの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US8198094B2 (enExample) |
| EP (2) | EP2001496B1 (enExample) |
| JP (5) | JP5322917B2 (enExample) |
| KR (2) | KR20140091048A (enExample) |
| CN (2) | CN107085113B (enExample) |
| AU (1) | AU2007227613A1 (enExample) |
| CA (1) | CA2680413C (enExample) |
| DK (2) | DK3279663T3 (enExample) |
| ES (2) | ES2895078T3 (enExample) |
| HU (2) | HUE035884T2 (enExample) |
| PL (2) | PL3279663T3 (enExample) |
| PT (2) | PT3279663T (enExample) |
| WO (1) | WO2007109056A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9408891B2 (en) | 2003-11-12 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Methods of using gelsolin to treat or prevent bacterial sepsis |
| ES2848385T3 (es) * | 2003-11-12 | 2021-08-09 | Univ Pennsylvania | Métodos de uso de gelsolina para tratar o prevenir septicemia bacteriana |
| CA2607686C (en) | 2004-05-12 | 2014-11-04 | Thomas P. Stossel | Use of gelsolin to treat infections |
| JP4348631B2 (ja) * | 2005-03-29 | 2009-10-21 | セイコーエプソン株式会社 | 半導体素子の製造方法 |
| AU2007227613A1 (en) | 2006-03-15 | 2007-09-27 | The Brigham And Women's Hospital, Inc. | Use of gelsolin to diagnose and treat inflammatory diseases |
| EP2002258B1 (en) | 2006-03-15 | 2017-09-27 | The Brigham and Women's Hospital, Inc. | Use of gelsolin to treat multiple sclerosis and to diagnose neurologic diseases |
| US7526337B2 (en) * | 2006-06-06 | 2009-04-28 | Cardiac Pacemakers, Inc. | Method and device for lymphatic system monitoring |
| US20070282376A1 (en) | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and apparatus for neural stimulation via the lymphatic system |
| US7734341B2 (en) | 2006-06-06 | 2010-06-08 | Cardiac Pacemakers, Inc. | Method and apparatus for gastrointestinal stimulation via the lymphatic system |
| US8905999B2 (en) | 2006-09-01 | 2014-12-09 | Cardiac Pacemakers, Inc. | Method and apparatus for endolymphatic drug delivery |
| CN102119173B (zh) * | 2007-08-15 | 2015-04-08 | 北京同为时代生物技术有限公司 | 凝溶胶蛋白结合剂组合物及其用途 |
| JP5778425B2 (ja) * | 2008-01-25 | 2015-09-16 | ザ ジェネラル ホスピタル コーポレイション | 腎不全におけるゲルソリンの診断的および治療的使用 |
| EP2311823A1 (en) * | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
| DE102010026500A1 (de) * | 2010-07-07 | 2012-01-12 | Arthrogen Gmbh | Verfahren zur Herstellung von autologen Proteinen |
| KR102176971B1 (ko) * | 2012-07-05 | 2020-11-11 | 타이완 리포좀 캄파니 리미티드 | 관절염의 치료 방법 |
| KR101416954B1 (ko) * | 2012-09-12 | 2014-07-16 | 한양대학교 산학협력단 | 조혈세포 분화 유도 방법 |
| WO2015137738A1 (ko) * | 2014-03-11 | 2015-09-17 | 한양대학교 산학협력단 | 혈액질환 진단 |
| WO2016033187A1 (en) * | 2014-08-26 | 2016-03-03 | The Brigham And Women's Hospital, Inc. | Use of gelsolin in the treatment and diagnosis of sickle cell disease |
| WO2016040987A1 (en) * | 2014-09-15 | 2016-03-24 | Abregen Pty Ltd | Treating and/or preventing psoriasis |
| IT201700083044A1 (it) * | 2017-07-20 | 2019-01-20 | Laura Stronati | “uso della gelsolina come marcatore diagnostico e prognostico delle malattie infiammatorie intestinali” |
| US12369883B2 (en) | 2020-06-19 | 2025-07-29 | Ultrasound AI, Inc. | Artificial intelligence system for determining clinical values through medical imaging |
| US11266376B2 (en) | 2020-06-19 | 2022-03-08 | Ultrasound Ai Inc. | Premature birth prediction |
| EP4204818A1 (en) * | 2020-09-23 | 2023-07-05 | Bioaegis Therapeutics Inc. | Compositions and methods for identifying and treating microparticle-associated diseases and conditions |
| US20230357388A1 (en) * | 2020-09-25 | 2023-11-09 | The Francis Crick Institute Limited | Immunotherapy |
| CN112630430B (zh) * | 2020-11-16 | 2021-08-27 | 北京美联泰科生物技术有限公司 | 一种定量检测uchl-1的试剂盒及其应用 |
| KR20250161553A (ko) * | 2023-03-13 | 2025-11-17 | 울트라사운드 에이아이, 인코포레이티드 | 의료 이미징을 통한 포괄적인 의료 진단, 예후, 및 치료 최적화를 위한 인공 지능 시스템 |
Family Cites Families (72)
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|---|---|---|---|---|
| US5071773A (en) | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
| CA2016227A1 (en) | 1989-05-18 | 1990-11-18 | Xandra O. Breakefield | Genetic diagnosis of torsion dystonia |
| ATE171625T1 (de) | 1990-04-11 | 1998-10-15 | Brigham & Womens Hospital | Therapeutische verwendung von actin-bindenden verbindungen |
| US5464817A (en) | 1990-04-11 | 1995-11-07 | Brigham And Women's Hospital | Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I |
| JPH05501503A (ja) | 1990-05-04 | 1993-03-25 | バイオジェン,インコーポレイテッド | 多量体ゲルゾリン融合構築物 |
| US5571511A (en) | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
| JP3507486B2 (ja) | 1991-03-15 | 2004-03-15 | アムジエン・インコーポレーテツド | 顆粒球コロニー刺激因子の肺内投与 |
| US5360350A (en) | 1991-08-23 | 1994-11-01 | The Whitaker Corporation | Sealant compositions and sealed electrical connectors |
| WO1994003601A2 (en) | 1992-08-03 | 1994-02-17 | New York University | Cloning, expression and uses for neurocan as a chondroitin sulfate proteoglycan |
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| WO1994008049A1 (en) | 1992-10-01 | 1994-04-14 | The General Hospital Corporation | Functional assay for tumor suppressor genes |
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| JP3914272B2 (ja) | 1993-12-28 | 2007-05-16 | 中外製薬株式会社 | アドゼベリンをコードする遺伝子 |
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| US5563153A (en) | 1995-02-22 | 1996-10-08 | University Of Kansas Medical Center | Sterile topical anesthetic gel |
| CA2214247C (en) | 1995-03-14 | 2004-02-10 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
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| AU3817497A (en) | 1996-07-30 | 1998-02-20 | Biogen, Inc. | Production of recombinant plasma gelsolin containing a disulfide bond |
| JP2001505219A (ja) | 1996-12-04 | 2001-04-17 | ザ・ビクトリア・ユニバーシティ・オブ・マンチェスター | 創傷の治癒および線維症の治療 |
| EP1003501B9 (en) * | 1997-04-02 | 2005-06-08 | The Brigham And Women's Hospital, Inc. | Use of an agent for lowering the risk of cardiovascular disease |
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| AU2002306651B2 (en) * | 2001-03-02 | 2007-12-13 | Medimmune, Llc | Methods of preventing or treating inflammatory or autoimmune disorders by administering integrin alphav Beta3 antagonists |
| EP1249244A1 (en) | 2001-04-13 | 2002-10-16 | Universiteit Gent | Therapeutic compositions for the treatment of a disease modulated by the G-actin / F-actin equilibrium, especially a respiratory tract disease |
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| EP2266595A3 (en) | 2002-02-06 | 2011-07-06 | Regenerx Biopharmaceuticals, Inc. | Treatment of infections and other disorders |
| WO2003088811A2 (en) | 2002-04-16 | 2003-10-30 | The Brigham And Women's Hospital, Inc. | Gelsolin as a prognostic marker of artherosclerotic diseases |
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| GB0327723D0 (en) | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
| ES2848385T3 (es) | 2003-11-12 | 2021-08-09 | Univ Pennsylvania | Métodos de uso de gelsolina para tratar o prevenir septicemia bacteriana |
| US9408891B2 (en) * | 2003-11-12 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Methods of using gelsolin to treat or prevent bacterial sepsis |
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| CA2607686C (en) * | 2004-05-12 | 2014-11-04 | Thomas P. Stossel | Use of gelsolin to treat infections |
| EP1753455A2 (en) | 2004-06-04 | 2007-02-21 | Genentech, Inc. | Method for treating multiple sclerosis |
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| EP2002258B1 (en) | 2006-03-15 | 2017-09-27 | The Brigham and Women's Hospital, Inc. | Use of gelsolin to treat multiple sclerosis and to diagnose neurologic diseases |
| AU2007227613A1 (en) | 2006-03-15 | 2007-09-27 | The Brigham And Women's Hospital, Inc. | Use of gelsolin to diagnose and treat inflammatory diseases |
| JP5778425B2 (ja) | 2008-01-25 | 2015-09-16 | ザ ジェネラル ホスピタル コーポレイション | 腎不全におけるゲルソリンの診断的および治療的使用 |
| KR101568323B1 (ko) | 2014-01-08 | 2015-11-12 | 한국원자력의학원 | 겔솔린을 유효성분으로 포함하는 수지상세포 분화 유도용 조성물 및 이의 분화 유도방법 |
| WO2016033187A1 (en) | 2014-08-26 | 2016-03-03 | The Brigham And Women's Hospital, Inc. | Use of gelsolin in the treatment and diagnosis of sickle cell disease |
-
2007
- 2007-03-15 AU AU2007227613A patent/AU2007227613A1/en not_active Abandoned
- 2007-03-15 DK DK17173554.1T patent/DK3279663T3/da active
- 2007-03-15 WO PCT/US2007/006451 patent/WO2007109056A2/en not_active Ceased
- 2007-03-15 ES ES17173554T patent/ES2895078T3/es active Active
- 2007-03-15 EP EP07753102.8A patent/EP2001496B1/en active Active
- 2007-03-15 ES ES07753102.8T patent/ES2641879T3/es active Active
- 2007-03-15 EP EP17173554.1A patent/EP3279663B1/en active Active
- 2007-03-15 CN CN201610875666.0A patent/CN107085113B/zh active Active
- 2007-03-15 HU HUE07753102A patent/HUE035884T2/en unknown
- 2007-03-15 KR KR1020147015554A patent/KR20140091048A/ko not_active Ceased
- 2007-03-15 JP JP2009500462A patent/JP5322917B2/ja active Active
- 2007-03-15 PL PL17173554T patent/PL3279663T3/pl unknown
- 2007-03-15 PT PT171735541T patent/PT3279663T/pt unknown
- 2007-03-15 US US12/225,128 patent/US8198094B2/en active Active
- 2007-03-15 HU HUE17173554A patent/HUE056086T2/hu unknown
- 2007-03-15 DK DK07753102.8T patent/DK2001496T3/en active
- 2007-03-15 PL PL07753102T patent/PL2001496T3/pl unknown
- 2007-03-15 PT PT77531028T patent/PT2001496T/pt unknown
- 2007-03-15 KR KR1020087025043A patent/KR101556790B1/ko active Active
- 2007-03-15 CN CNA2007800175589A patent/CN101443030A/zh active Pending
- 2007-03-15 CA CA2680413A patent/CA2680413C/en active Active
-
2011
- 2011-12-09 JP JP2011270249A patent/JP2012083359A/ja not_active Withdrawn
-
2012
- 2012-04-25 US US13/455,878 patent/US9316639B2/en active Active
-
2014
- 2014-03-31 JP JP2014071355A patent/JP2014122924A/ja not_active Withdrawn
-
2015
- 2015-07-09 JP JP2015137491A patent/JP6198777B2/ja active Active
-
2016
- 2016-04-18 US US15/131,465 patent/US10238715B2/en active Active
-
2017
- 2017-05-17 JP JP2017098198A patent/JP6568144B2/ja active Active
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