JP2009529337A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009529337A5 JP2009529337A5 JP2008558640A JP2008558640A JP2009529337A5 JP 2009529337 A5 JP2009529337 A5 JP 2009529337A5 JP 2008558640 A JP2008558640 A JP 2008558640A JP 2008558640 A JP2008558640 A JP 2008558640A JP 2009529337 A5 JP2009529337 A5 JP 2009529337A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- nucleotide
- analog
- hydrophobic
- target sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200600379 | 2006-03-16 | ||
| DKPA200600379 | 2006-03-16 | ||
| PCT/DK2007/000134 WO2007104318A2 (en) | 2006-03-16 | 2007-03-16 | Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009529337A JP2009529337A (ja) | 2009-08-20 |
| JP2009529337A5 true JP2009529337A5 (enExample) | 2010-07-08 |
| JP5284112B2 JP5284112B2 (ja) | 2013-09-11 |
Family
ID=38509827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008558640A Active JP5284112B2 (ja) | 2006-03-16 | 2007-03-16 | 核酸、メチル化状態及び核酸の突然変異体を検出するための、シグナリングペア及び疎水性ヌクレオチドを含んだオリゴヌクレオチド、ステムレスビーコン |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8133984B2 (enExample) |
| EP (1) | EP2004847B1 (enExample) |
| JP (1) | JP5284112B2 (enExample) |
| CN (1) | CN101448957A (enExample) |
| AU (1) | AU2007224843A1 (enExample) |
| CA (1) | CA2645136C (enExample) |
| DK (1) | DK2004847T3 (enExample) |
| NZ (1) | NZ571966A (enExample) |
| WO (1) | WO2007104318A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2229457A4 (en) | 2007-12-14 | 2011-01-26 | Minitube America Inc | SEX-SPECIFIC SEPARATION OF SPERM AND EMBRYOES |
| US20110053226A1 (en) * | 2008-06-13 | 2011-03-03 | Riboxx Gmbh | Method for enzymatic synthesis of chemically modified rna |
| DE102010012421B4 (de) | 2009-03-23 | 2023-04-20 | Vermicon Ag | Verfahren zum spezifischen Nachweis von Mikroorganismen |
| WO2011032034A2 (en) | 2009-09-10 | 2011-03-17 | University Of Idaho | Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids |
| JP5717169B2 (ja) * | 2010-09-14 | 2015-05-13 | 国立大学法人名古屋大学 | オリゴヌクレオチド及びその利用 |
| AU2012283994A1 (en) | 2011-07-19 | 2014-03-06 | University Of Idaho | Embodiments of a probe and method for targeting nucleic acids |
| EP2820157B1 (en) | 2012-03-02 | 2019-05-01 | Winthrop-University Hospital | Method for using probe based pcr detection to measure the levels of circulating demethylated beta cell derived dna as a measure of beta cell loss in diabetes |
| CN102911111B (zh) * | 2012-11-08 | 2014-06-11 | 齐鲁工业大学 | 一种咔唑苯甲醛缩对苯二胺双席夫碱及其制备方法 |
| US10988810B2 (en) | 2015-09-14 | 2021-04-27 | Pentabase Aps | Methods and materials for detection of mutations |
| WO2017218858A1 (en) | 2016-06-15 | 2017-12-21 | Genecapture, Inc. | Compositions, methods and devices comprising stem-loop captor molecules |
| CN108827935B (zh) * | 2018-06-08 | 2021-09-07 | 南京师范大学 | 一种基于金纳米孔阵列的dna甲基化表面增强拉曼散射光谱检测方法及其应用 |
| IL280880B2 (en) | 2018-08-27 | 2025-04-01 | Regeneron Pharma | Using Raman Spectroscopy in Downstream Purification |
| CN114286865A (zh) * | 2019-05-13 | 2022-04-05 | 潘塔贝斯公司 | 检测变体核酸的解链温度方法、试剂盒和报告寡核苷酸 |
| CN110261964B (zh) * | 2019-07-01 | 2021-06-04 | 国检中心深圳珠宝检验实验室有限公司 | 一种用于光纤光谱仪的光纤头 |
| AU2021302551A1 (en) * | 2020-06-29 | 2023-01-05 | Pentabase Aps | Detection of methylation status |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5466578A (en) * | 1992-04-09 | 1995-11-14 | The United States Of America As Represented By The Secretary Of The Navy | Surfactant-enhanced light emission- or absorbance-based binding assays for polynucleic acids |
| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US6312894B1 (en) * | 1995-04-03 | 2001-11-06 | Epoch Pharmaceuticals, Inc. | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders |
| DE69610304T2 (de) * | 1995-05-05 | 2001-04-05 | Perkin-Elmer Corp., Foster City | Methoden and reagentien fuer die kombination einer pcr-amplifizierung mit einem hybridisierungs-assay |
| DE69738687D1 (de) * | 1996-04-12 | 2008-06-26 | Phri Properties Inc | Sonden, kits und assays |
| JPH11332595A (ja) | 1997-07-09 | 1999-12-07 | Masao Karube | プローブｐｎａによるｄｎａの検出方法 |
| KR100414936B1 (ko) | 1997-09-12 | 2004-01-13 | 엑시콘 에이/에스 | 이환 및 삼환 뉴클레오시드, 뉴클레오타이드 및올리고뉴클레오타이드 동족체 |
| EP1025120B1 (en) * | 1997-10-27 | 2010-08-18 | Boston Probes, Inc. | Methods, kits and compositions pertaining to pna molecular beacons |
| US6485901B1 (en) | 1997-10-27 | 2002-11-26 | Boston Probes, Inc. | Methods, kits and compositions pertaining to linear beacons |
| US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
| US20070059752A1 (en) * | 1999-06-09 | 2007-03-15 | Biosearch Technologies, Inc. | Fluorescence energy transfer probes with stabilized conformations |
| DK1715063T3 (da) | 2000-03-29 | 2011-05-16 | Lgc Ltd | Hydridiseringsbeacon og fremgangsmåde til hurtig sekvensdetektion og distinktion |
| WO2003043402A2 (en) * | 2001-10-19 | 2003-05-30 | Proligo Llc | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes |
| AU2002358462A1 (en) | 2001-12-18 | 2003-06-30 | Human Genetic Signatures Pty Ltd | Linear and hairpin oligonucleotide analogues comprising intercalator pseudonucleotides |
| US20040086879A1 (en) * | 2001-12-20 | 2004-05-06 | Yingufu Li | Tripartite molecular beacons |
| AU2003213557A1 (en) * | 2002-02-27 | 2003-09-09 | Biosource International Inc. | Methods of using FET labeled oligonucleotides that include a 3' - 5' exonuclease resistant quencher domain and compositions for practicing the same |
| GB0223563D0 (en) | 2002-10-10 | 2002-11-20 | Secr Defence | Detection system |
| GB0319949D0 (en) | 2003-08-26 | 2003-09-24 | Univ Strathclyde | Nucleic acid sequence identification |
| JP5162133B2 (ja) * | 2003-12-03 | 2013-03-13 | アボット・ラボラトリーズ | 二本鎖直鎖核酸プローブ及びその使用 |
-
2007
- 2007-03-16 DK DK07711277.9T patent/DK2004847T3/en active
- 2007-03-16 CA CA2645136A patent/CA2645136C/en active Active
- 2007-03-16 US US12/293,201 patent/US8133984B2/en active Active
- 2007-03-16 AU AU2007224843A patent/AU2007224843A1/en not_active Abandoned
- 2007-03-16 CN CNA200780017820XA patent/CN101448957A/zh active Pending
- 2007-03-16 WO PCT/DK2007/000134 patent/WO2007104318A2/en not_active Ceased
- 2007-03-16 JP JP2008558640A patent/JP5284112B2/ja active Active
- 2007-03-16 EP EP07711277.9A patent/EP2004847B1/en active Active
- 2007-03-16 NZ NZ571966A patent/NZ571966A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009529337A5 (enExample) | ||
| JP2009521223A5 (enExample) | ||
| KR101072900B1 (ko) | 고정화된 펩티드핵산 프로브를 사용한 표적핵산의 선택적 표지 및 검출 방법 | |
| JP2012531202A5 (enExample) | ||
| CA2532160A1 (en) | Methods of genotyping using differences in melting temperature | |
| CN108368557B (zh) | 基于等温的双功能性寡聚核苷酸及利用其的核酸扩增和测定方法 | |
| FI3957753T3 (fi) | Polymeraasiketjureaktion primeerejä ja koettimia mycobacterium tuberculosista varten | |
| JP6638122B2 (ja) | 標的核酸の検出方法及びキット | |
| JP2013513360A5 (enExample) | ||
| CN113046424B (zh) | 一种用于pcr检测的核酸组合物的制备方法及其制备的核酸组合物和pcr检测方法 | |
| KR102488559B1 (ko) | 가닥-침투 기반 dna 증폭방법 | |
| JP2010035532A (ja) | アレル特異的ｐｃｒ法 | |
| JP2008237140A (ja) | Ｎ−アセチルトランスフェラーゼ２（ｎａｔ２）の遺伝子型を検出するための核酸プライマーセット及び核酸プローブ | |
| JP2008278779A (ja) | 核酸ハイブリダイゼーション用溶液 | |
| RU2009125014A (ru) | Способ определения гаплотипа множественных аллельных генов | |
| JP5692774B2 (ja) | 一塩基多型を検出する方法および試薬キット | |
| WO2016098595A1 (ja) | 一塩基多型検出用オリゴヌクレオチドプローブ及び一塩基多型検出方法 | |
| Tedeschi et al. | A PNA microarray for tomato genotyping | |
| JP2012239424A (ja) | 核酸塩基配列解析方法および核酸塩基配列解析のためのマイクロチップと混合試薬 | |
| JP4399025B1 (ja) | Ｎ−アセチルトランスフェラーゼ２（ｎａｔ２）の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法 | |
| JP4399024B1 (ja) | Ｎ−アセチルトランスフェラーゼ２（ｎａｔ２）の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法 | |
| CN111378749A (zh) | 检测DYNC2H1基因rs716274位点多态性的人工模拟核酸分子信标与试剂盒 | |
| ATE404697T1 (de) | Verfahren zum nachweis von genetischem polymorphismus | |
| CN111378746A (zh) | 检测CASP7基因rs12415607位点多态性的人工模拟核酸分子信标与试剂盒 | |
| CN111593122A (zh) | 检测XPC基因rs2228001位点多态性的人工模拟核酸分子信标与试剂盒 |