JP2009529337A5 - - Google Patents
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- Publication number
- JP2009529337A5 JP2009529337A5 JP2008558640A JP2008558640A JP2009529337A5 JP 2009529337 A5 JP2009529337 A5 JP 2009529337A5 JP 2008558640 A JP2008558640 A JP 2008558640A JP 2008558640 A JP2008558640 A JP 2008558640A JP 2009529337 A5 JP2009529337 A5 JP 2009529337A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- nucleotide
- analog
- hydrophobic
- target sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200600379 | 2006-03-16 | ||
| DKPA200600379 | 2006-03-16 | ||
| PCT/DK2007/000134 WO2007104318A2 (en) | 2006-03-16 | 2007-03-16 | Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009529337A JP2009529337A (ja) | 2009-08-20 |
| JP2009529337A5 true JP2009529337A5 (enExample) | 2010-07-08 |
| JP5284112B2 JP5284112B2 (ja) | 2013-09-11 |
Family
ID=38509827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008558640A Active JP5284112B2 (ja) | 2006-03-16 | 2007-03-16 | 核酸、メチル化状態及び核酸の突然変異体を検出するための、シグナリングペア及び疎水性ヌクレオチドを含んだオリゴヌクレオチド、ステムレスビーコン |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8133984B2 (enExample) |
| EP (1) | EP2004847B1 (enExample) |
| JP (1) | JP5284112B2 (enExample) |
| CN (1) | CN101448957A (enExample) |
| AU (1) | AU2007224843A1 (enExample) |
| CA (1) | CA2645136C (enExample) |
| DK (1) | DK2004847T3 (enExample) |
| NZ (1) | NZ571966A (enExample) |
| WO (1) | WO2007104318A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2708751A1 (en) | 2007-12-14 | 2009-06-25 | Minitube Of America, Inc. | Gender-specific separation of sperm cells and embryos |
| US20110053226A1 (en) * | 2008-06-13 | 2011-03-03 | Riboxx Gmbh | Method for enzymatic synthesis of chemically modified rna |
| DE102010012421B4 (de) | 2009-03-23 | 2023-04-20 | Vermicon Ag | Verfahren zum spezifischen Nachweis von Mikroorganismen |
| WO2011032034A2 (en) | 2009-09-10 | 2011-03-17 | University Of Idaho | Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids |
| JP5717169B2 (ja) * | 2010-09-14 | 2015-05-13 | 国立大学法人名古屋大学 | オリゴヌクレオチド及びその利用 |
| BR112014001075A2 (pt) | 2011-07-19 | 2016-11-29 | Univ Idaho | sonda, seu uso, método in vitro para associar uma sonda com um alvo e kit |
| WO2013131083A1 (en) | 2012-03-02 | 2013-09-06 | Winthrop-University Hospital | METHOD FOR USING PROBE BASED PCR DETECTION TO MEASURE THE LEVELS OF CIRCULATING DEMETHYLATED β CELL DERIVED DNA AS A MEASURE OF β CELL LOSS IN DIABETES |
| CN102911111B (zh) * | 2012-11-08 | 2014-06-11 | 齐鲁工业大学 | 一种咔唑苯甲醛缩对苯二胺双席夫碱及其制备方法 |
| EP3350347B1 (en) | 2015-09-14 | 2021-01-20 | Pentabase APS | Methods and materials for detection of mutations |
| CN109790565A (zh) | 2016-06-15 | 2019-05-21 | 基因捕获公司 | 包含茎-环捕获分子的组合物、方法和装置 |
| CN108827935B (zh) * | 2018-06-08 | 2021-09-07 | 南京师范大学 | 一种基于金纳米孔阵列的dna甲基化表面增强拉曼散射光谱检测方法及其应用 |
| CN119264211A (zh) | 2018-08-27 | 2025-01-07 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| KR20220031544A (ko) * | 2019-05-13 | 2022-03-11 | 펜타베이스 에이피에스 | 변이체 핵산 검출을 위한 용융 온도 방법, 키트 및 리포터 올리고 |
| CN110261964B (zh) * | 2019-07-01 | 2021-06-04 | 国检中心深圳珠宝检验实验室有限公司 | 一种用于光纤光谱仪的光纤头 |
| AU2021302551A1 (en) * | 2020-06-29 | 2023-01-05 | Pentabase Aps | Detection of methylation status |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5466578A (en) | 1992-04-09 | 1995-11-14 | The United States Of America As Represented By The Secretary Of The Navy | Surfactant-enhanced light emission- or absorbance-based binding assays for polynucleic acids |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US6312894B1 (en) | 1995-04-03 | 2001-11-06 | Epoch Pharmaceuticals, Inc. | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders |
| AU693023B2 (en) | 1995-05-05 | 1998-06-18 | Applied Biosystems, Llc | Methods and reagents for combined PCR amplification and hybridization probing assay |
| AU713667B2 (en) | 1996-04-12 | 1999-12-09 | Phri Properties, Inc. | Detection probes, kits and assays |
| JPH11332595A (ja) | 1997-07-09 | 1999-12-07 | Masao Karube | プローブｐｎａによるｄｎａの検出方法 |
| JP4236812B2 (ja) | 1997-09-12 | 2009-03-11 | エクシコン エ／エス | オリゴヌクレオチド類似体 |
| ATE478090T1 (de) | 1997-10-27 | 2010-09-15 | Boston Probes Inc | SICH AUF ßPNA MOLECULAR BEACONSß BEZIEHENDE VERFAHREN, TESTSÄTZE UND ZUSAMMENSETZUNGEN |
| US6485901B1 (en) | 1997-10-27 | 2002-11-26 | Boston Probes, Inc. | Methods, kits and compositions pertaining to linear beacons |
| US6037130A (en) | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
| US20070059752A1 (en) * | 1999-06-09 | 2007-03-15 | Biosearch Technologies, Inc. | Fluorescence energy transfer probes with stabilized conformations |
| EP1278889B1 (en) | 2000-03-29 | 2006-07-26 | LGC Limited | Hybridisation beacon and method of rapid sequence detection and discrimination |
| US6902900B2 (en) * | 2001-10-19 | 2005-06-07 | Prolico, Llc | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes |
| AU2002358464B2 (en) | 2001-12-18 | 2006-04-27 | Human Genetic Signatures Pty Ltd | Pseudonucleotide comprising an intercalator |
| US20040086879A1 (en) | 2001-12-20 | 2004-05-06 | Yingufu Li | Tripartite molecular beacons |
| JP4481656B2 (ja) * | 2002-02-27 | 2010-06-16 | ライフ テクノロジーズ コーポレーション | ３’→５’エキソヌクレアーゼ耐性クエンチャードメインを含むｆｅｔ標識オリゴヌクレオチドを使用する方法およびそれを実施するための組成物 |
| GB0223563D0 (en) | 2002-10-10 | 2002-11-20 | Secr Defence | Detection system |
| GB0319949D0 (en) | 2003-08-26 | 2003-09-24 | Univ Strathclyde | Nucleic acid sequence identification |
| ES2385485T3 (es) | 2003-12-03 | 2012-07-25 | Abbott Laboratories | Sonda de ácido nucleico lineal de doble hebra y usos de la misma |
-
2007
- 2007-03-16 CA CA2645136A patent/CA2645136C/en active Active
- 2007-03-16 NZ NZ571966A patent/NZ571966A/en unknown
- 2007-03-16 JP JP2008558640A patent/JP5284112B2/ja active Active
- 2007-03-16 EP EP07711277.9A patent/EP2004847B1/en active Active
- 2007-03-16 WO PCT/DK2007/000134 patent/WO2007104318A2/en not_active Ceased
- 2007-03-16 CN CNA200780017820XA patent/CN101448957A/zh active Pending
- 2007-03-16 AU AU2007224843A patent/AU2007224843A1/en not_active Abandoned
- 2007-03-16 DK DK07711277.9T patent/DK2004847T3/en active
- 2007-03-16 US US12/293,201 patent/US8133984B2/en active Active
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