NZ571966A - Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids - Google Patents

Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids

Info

Publication number
NZ571966A
NZ571966A NZ571966A NZ57196607A NZ571966A NZ 571966 A NZ571966 A NZ 571966A NZ 571966 A NZ571966 A NZ 571966A NZ 57196607 A NZ57196607 A NZ 57196607A NZ 571966 A NZ571966 A NZ 571966A
Authority
NZ
New Zealand
Prior art keywords
oligonucleotide
hydrophobic
nucleotide
analogue
oligonucleotide analogue
Prior art date
Application number
NZ571966A
Other languages
English (en)
Inventor
Ulf Bech Christensen
Original Assignee
Pentabase Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentabase Aps filed Critical Pentabase Aps
Publication of NZ571966A publication Critical patent/NZ571966A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ571966A 2006-03-16 2007-03-16 Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids NZ571966A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200600379 2006-03-16
PCT/DK2007/000134 WO2007104318A2 (en) 2006-03-16 2007-03-16 Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids

Publications (1)

Publication Number Publication Date
NZ571966A true NZ571966A (en) 2011-09-30

Family

ID=38509827

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ571966A NZ571966A (en) 2006-03-16 2007-03-16 Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids

Country Status (9)

Country Link
US (1) US8133984B2 (enExample)
EP (1) EP2004847B1 (enExample)
JP (1) JP5284112B2 (enExample)
CN (1) CN101448957A (enExample)
AU (1) AU2007224843A1 (enExample)
CA (1) CA2645136C (enExample)
DK (1) DK2004847T3 (enExample)
NZ (1) NZ571966A (enExample)
WO (1) WO2007104318A2 (enExample)

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Publication number Priority date Publication date Assignee Title
EP2229457A4 (en) 2007-12-14 2011-01-26 Minitube America Inc SEX-SPECIFIC SEPARATION OF SPERM AND EMBRYOES
US20110053226A1 (en) * 2008-06-13 2011-03-03 Riboxx Gmbh Method for enzymatic synthesis of chemically modified rna
DE102010012421B4 (de) 2009-03-23 2023-04-20 Vermicon Ag Verfahren zum spezifischen Nachweis von Mikroorganismen
WO2011032034A2 (en) 2009-09-10 2011-03-17 University Of Idaho Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids
JP5717169B2 (ja) * 2010-09-14 2015-05-13 国立大学法人名古屋大学 オリゴヌクレオチド及びその利用
AU2012283994A1 (en) 2011-07-19 2014-03-06 University Of Idaho Embodiments of a probe and method for targeting nucleic acids
EP2820157B1 (en) 2012-03-02 2019-05-01 Winthrop-University Hospital Method for using probe based pcr detection to measure the levels of circulating demethylated beta cell derived dna as a measure of beta cell loss in diabetes
CN102911111B (zh) * 2012-11-08 2014-06-11 齐鲁工业大学 一种咔唑苯甲醛缩对苯二胺双席夫碱及其制备方法
US10988810B2 (en) 2015-09-14 2021-04-27 Pentabase Aps Methods and materials for detection of mutations
WO2017218858A1 (en) 2016-06-15 2017-12-21 Genecapture, Inc. Compositions, methods and devices comprising stem-loop captor molecules
CN108827935B (zh) * 2018-06-08 2021-09-07 南京师范大学 一种基于金纳米孔阵列的dna甲基化表面增强拉曼散射光谱检测方法及其应用
IL280880B2 (en) 2018-08-27 2025-04-01 Regeneron Pharma Using Raman Spectroscopy in Downstream Purification
CN114286865A (zh) * 2019-05-13 2022-04-05 潘塔贝斯公司 检测变体核酸的解链温度方法、试剂盒和报告寡核苷酸
CN110261964B (zh) * 2019-07-01 2021-06-04 国检中心深圳珠宝检验实验室有限公司 一种用于光纤光谱仪的光纤头
AU2021302551A1 (en) * 2020-06-29 2023-01-05 Pentabase Aps Detection of methylation status

Family Cites Families (19)

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US5466578A (en) * 1992-04-09 1995-11-14 The United States Of America As Represented By The Secretary Of The Navy Surfactant-enhanced light emission- or absorbance-based binding assays for polynucleic acids
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US6312894B1 (en) * 1995-04-03 2001-11-06 Epoch Pharmaceuticals, Inc. Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
DE69610304T2 (de) * 1995-05-05 2001-04-05 Perkin-Elmer Corp., Foster City Methoden and reagentien fuer die kombination einer pcr-amplifizierung mit einem hybridisierungs-assay
DE69738687D1 (de) * 1996-04-12 2008-06-26 Phri Properties Inc Sonden, kits und assays
JPH11332595A (ja) 1997-07-09 1999-12-07 Masao Karube プローブｐｎａによるｄｎａの検出方法
KR100414936B1 (ko) 1997-09-12 2004-01-13 엑시콘 에이/에스 이환 및 삼환 뉴클레오시드, 뉴클레오타이드 및올리고뉴클레오타이드 동족체
EP1025120B1 (en) * 1997-10-27 2010-08-18 Boston Probes, Inc. Methods, kits and compositions pertaining to pna molecular beacons
US6485901B1 (en) 1997-10-27 2002-11-26 Boston Probes, Inc. Methods, kits and compositions pertaining to linear beacons
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
US20070059752A1 (en) * 1999-06-09 2007-03-15 Biosearch Technologies, Inc. Fluorescence energy transfer probes with stabilized conformations
DK1715063T3 (da) 2000-03-29 2011-05-16 Lgc Ltd Hydridiseringsbeacon og fremgangsmåde til hurtig sekvensdetektion og distinktion
WO2003043402A2 (en) * 2001-10-19 2003-05-30 Proligo Llc Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes
AU2002358462A1 (en) 2001-12-18 2003-06-30 Human Genetic Signatures Pty Ltd Linear and hairpin oligonucleotide analogues comprising intercalator pseudonucleotides
US20040086879A1 (en) * 2001-12-20 2004-05-06 Yingufu Li Tripartite molecular beacons
AU2003213557A1 (en) * 2002-02-27 2003-09-09 Biosource International Inc. Methods of using FET labeled oligonucleotides that include a 3' - 5' exonuclease resistant quencher domain and compositions for practicing the same
GB0223563D0 (en) 2002-10-10 2002-11-20 Secr Defence Detection system
GB0319949D0 (en) 2003-08-26 2003-09-24 Univ Strathclyde Nucleic acid sequence identification
JP5162133B2 (ja) * 2003-12-03 2013-03-13 アボット・ラボラトリーズ 二本鎖直鎖核酸プローブ及びその使用

Also Published As

Publication number Publication date
DK2004847T3 (en) 2017-08-21
EP2004847B1 (en) 2017-05-03
US20100068704A1 (en) 2010-03-18
WO2007104318A2 (en) 2007-09-20
EP2004847A2 (en) 2008-12-24
WO2007104318A3 (en) 2008-03-20
JP5284112B2 (ja) 2013-09-11
CN101448957A (zh) 2009-06-03
JP2009529337A (ja) 2009-08-20
CA2645136C (en) 2017-09-19
US8133984B2 (en) 2012-03-13
CA2645136A1 (en) 2007-09-20
AU2007224843A1 (en) 2007-09-20

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