JP2009526862A5 - - Google Patents
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- JP2009526862A5 JP2009526862A5 JP2008555414A JP2008555414A JP2009526862A5 JP 2009526862 A5 JP2009526862 A5 JP 2009526862A5 JP 2008555414 A JP2008555414 A JP 2008555414A JP 2008555414 A JP2008555414 A JP 2008555414A JP 2009526862 A5 JP2009526862 A5 JP 2009526862A5
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- 239000000203 mixture Substances 0.000 claims 42
- 239000000758 substrate Substances 0.000 claims 28
- 108090000765 processed proteins & peptides Proteins 0.000 claims 22
- 229920000642 polymer Polymers 0.000 claims 9
- 230000000844 anti-bacterial effect Effects 0.000 claims 6
- 102000044503 Antimicrobial Peptides Human genes 0.000 claims 5
- 108700042778 Antimicrobial Peptides Proteins 0.000 claims 5
- 239000003910 polypeptide antibiotic agent Substances 0.000 claims 5
- 125000003396 thiol group Chemical class [H]S* 0.000 claims 5
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 5
- 230000000845 anti-microbial effect Effects 0.000 claims 4
- 229940039227 diagnostic agent Drugs 0.000 claims 4
- 239000000032 diagnostic agent Substances 0.000 claims 4
- 230000000069 prophylactic effect Effects 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 4
- 229920002554 vinyl polymer Polymers 0.000 claims 4
- 150000001412 amines Chemical class 0.000 claims 3
- 238000004873 anchoring Methods 0.000 claims 3
- 239000007822 coupling agent Substances 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- YYROPELSRYBVMQ-UHFFFAOYSA-N 4-toluenesulfonyl chloride Chemical compound CC1=CC=C(S(Cl)(=O)=O)C=C1 YYROPELSRYBVMQ-UHFFFAOYSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 230000004913 activation Effects 0.000 claims 2
- -1 acyl azide Chemical class 0.000 claims 2
- 150000001299 aldehydes Chemical class 0.000 claims 2
- 150000002118 epoxides Chemical class 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 150000004820 halides Chemical class 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical group NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical group [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 238000007259 addition reaction Methods 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 238000007098 aminolysis reaction Methods 0.000 claims 1
- 150000008064 anhydrides Chemical class 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000003373 anti-fouling effect Effects 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229960004676 antithrombotic agent Drugs 0.000 claims 1
- 239000003125 aqueous solvent Substances 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 239000002639 bone cement Substances 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000002843 carboxylic acid group Chemical group 0.000 claims 1
- 230000021164 cell adhesion Effects 0.000 claims 1
- 239000000919 ceramic Substances 0.000 claims 1
- 239000013522 chelant Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000005229 chemical vapour deposition Methods 0.000 claims 1
- 238000004140 cleaning Methods 0.000 claims 1
- 238000007334 copolymerization reaction Methods 0.000 claims 1
- 229920006037 cross link polymer Polymers 0.000 claims 1
- 239000000824 cytostatic agent Substances 0.000 claims 1
- 231100000433 cytotoxic Toxicity 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- AFOSIXZFDONLBT-UHFFFAOYSA-N divinyl sulfone Chemical group C=CS(=O)(=O)C=C AFOSIXZFDONLBT-UHFFFAOYSA-N 0.000 claims 1
- 125000003700 epoxy group Chemical group 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 230000002949 hemolytic effect Effects 0.000 claims 1
- 230000007062 hydrolysis Effects 0.000 claims 1
- 238000006460 hydrolysis reaction Methods 0.000 claims 1
- 229920001477 hydrophilic polymer Polymers 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 238000010884 ion-beam technique Methods 0.000 claims 1
- 150000002540 isothiocyanates Chemical class 0.000 claims 1
- 150000002596 lactones Chemical class 0.000 claims 1
- 238000002386 leaching Methods 0.000 claims 1
- 125000005439 maleimidyl group Chemical group C1(C=CC(N1*)=O)=O 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 229910052759 nickel Inorganic materials 0.000 claims 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 1
- 231100000065 noncytotoxic Toxicity 0.000 claims 1
- 230000002020 noncytotoxic effect Effects 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- NMHMNPHRMNGLLB-UHFFFAOYSA-N phloretic acid Chemical compound OC(=O)CCC1=CC=C(O)C=C1 NMHMNPHRMNGLLB-UHFFFAOYSA-N 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 239000004814 polyurethane Substances 0.000 claims 1
- 238000006722 reduction reaction Methods 0.000 claims 1
- ULARYIUTHAWJMU-UHFFFAOYSA-M sodium;1-[4-(2,5-dioxopyrrol-1-yl)butanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate Chemical group [Na+].O=C1C(S(=O)(=O)[O-])CC(=O)N1OC(=O)CCCN1C(=O)C=CC1=O ULARYIUTHAWJMU-UHFFFAOYSA-M 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77405006P | 2006-02-15 | 2006-02-15 | |
| US11/561,266 US7739055B2 (en) | 2005-11-17 | 2006-11-17 | Methods and systems for generating and evaluating peptides |
| US88557807P | 2007-01-18 | 2007-01-18 | |
| PCT/US2007/004394 WO2007095393A2 (en) | 2006-02-15 | 2007-02-15 | Medical devices and coatings with non-leaching antimicrobial peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009526862A JP2009526862A (ja) | 2009-07-23 |
| JP2009526862A5 true JP2009526862A5 (enExample) | 2010-04-08 |
Family
ID=38372168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008555414A Withdrawn JP2009526862A (ja) | 2006-02-15 | 2007-02-15 | 非滲出性抗菌ペプチドを含む医療デバイスおよびコーティング |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20070254006A1 (enExample) |
| EP (1) | EP1991245A2 (enExample) |
| JP (1) | JP2009526862A (enExample) |
| CA (1) | CA2655168A1 (enExample) |
| WO (1) | WO2007095393A2 (enExample) |
Families Citing this family (81)
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| WO2012068179A1 (en) * | 2010-11-15 | 2012-05-24 | Rutgers, The State University Of New Jersey | Multifunctional biodegradable peg nanocarrier-based hydrogels for preventing hiv transmission |
| GB0808350D0 (en) * | 2008-05-09 | 2008-06-18 | Airbus Uk Ltd | Self-cleaning surfaces |
| GB0818074D0 (en) | 2008-10-02 | 2008-11-05 | Lytix Biopharma As | Treatment of biofilms |
| DE102008053892A1 (de) * | 2008-10-30 | 2010-05-06 | Fachhochschule Gelsenkirchen | Medizinisches Implantat mit biofunktionalisierter Oberfläche |
| ES2432388T3 (es) * | 2008-12-05 | 2013-12-03 | Semprus Biosciences Corporation | Composiciones antiincrustantes, antimicrobianas y antitrombogénicas de injerto desde la superficie |
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| EP2398850B1 (en) | 2009-02-21 | 2018-08-22 | Sofradim Production | Medical devices with an activated coating |
| WO2010095055A1 (en) | 2009-02-21 | 2010-08-26 | Sofradim Production | Crosslinked fibers and method of making same using uv radiation |
| US8968733B2 (en) | 2009-02-21 | 2015-03-03 | Sofradim Production | Functionalized surgical adhesives |
| US8512728B2 (en) | 2009-02-21 | 2013-08-20 | Sofradim Production | Method of forming a medical device on biological tissue |
| AU2010215931A1 (en) | 2009-02-21 | 2011-10-13 | Covidien Lp | Medical devices having activated surfaces |
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| DE19841585A1 (de) * | 1998-09-11 | 2000-03-16 | Rheinmetall W & M Gmbh | Waffenrohr mit einer im Bereich der Rohrmündung angeordneten Kollimatorhalterung |
| US6592814B2 (en) * | 1998-10-02 | 2003-07-15 | Johnson & Johnson Vision Care, Inc. | Biomedical devices with antimicrobial coatings |
| WO2000063079A1 (en) * | 1999-04-15 | 2000-10-26 | Ultracell Medical Technologies Of Connecticut, Inc. | Method for producing surgical sponge device and product thereof |
| ES2221850T3 (es) * | 1999-06-24 | 2005-01-16 | Abbott Vascular Devices Limited | Stents expandibles con balon. |
| EP1301571A2 (en) * | 2000-07-17 | 2003-04-16 | President And Fellows of Harvard College | Surfaces that resist the adsorption of biological species |
| US6844028B2 (en) * | 2001-06-26 | 2005-01-18 | Accelr8 Technology Corporation | Functional surface coating |
| US8172395B2 (en) * | 2002-12-03 | 2012-05-08 | Novartis Ag | Medical devices having antimicrobial coatings thereon |
| US7282214B2 (en) * | 2002-12-19 | 2007-10-16 | Johnson & Johnson Vision Care, Inc. | Biomedical devices with antimicrobial coatings |
| WO2005019241A2 (en) * | 2003-08-18 | 2005-03-03 | E.I. Dupont De Nemours And Company | Cationic antimicrobial peptides and compositions thereof |
| WO2005109158A2 (en) * | 2004-05-05 | 2005-11-17 | Massachusetts Institute Of Technology | Methods and systems for generating peptides |
| US20070048249A1 (en) * | 2005-08-24 | 2007-03-01 | Purdue Research Foundation | Hydrophilized bactericidal polymers |
| WO2007061850A2 (en) * | 2005-11-17 | 2007-05-31 | Massachusetts Institute Of Technology | Methods and systems for generating and evaluating peptides |
-
2007
- 2007-02-15 EP EP07751170A patent/EP1991245A2/en not_active Withdrawn
- 2007-02-15 JP JP2008555414A patent/JP2009526862A/ja not_active Withdrawn
- 2007-02-15 CA CA002655168A patent/CA2655168A1/en not_active Abandoned
- 2007-02-15 US US11/675,500 patent/US20070254006A1/en not_active Abandoned
- 2007-02-15 WO PCT/US2007/004394 patent/WO2007095393A2/en not_active Ceased
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