CA2655168A1 - Medical devices and coatings with non-leaching antimicrobial peptides - Google Patents

Medical devices and coatings with non-leaching antimicrobial peptides Download PDF

Info

Publication number
CA2655168A1
CA2655168A1 CA002655168A CA2655168A CA2655168A1 CA 2655168 A1 CA2655168 A1 CA 2655168A1 CA 002655168 A CA002655168 A CA 002655168A CA 2655168 A CA2655168 A CA 2655168A CA 2655168 A1 CA2655168 A1 CA 2655168A1
Authority
CA
Canada
Prior art keywords
composition
substrate
peptide
peptides
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002655168A
Other languages
English (en)
French (fr)
Inventor
Lino Ferreira
Robert S. Langer
Christopher R. Loose
William Shannan O'shaughnessy
Andreas Zumbuehl
Gregory Stephanopolous
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/561,266 external-priority patent/US7739055B2/en
Application filed by Individual filed Critical Individual
Publication of CA2655168A1 publication Critical patent/CA2655168A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/23Solid substances, e.g. granules, powders, blocks, tablets
    • A61L2/232Solid substances, e.g. granules, powders, blocks, tablets layered or coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25Peptides having up to 20 amino acids in a defined sequence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
CA002655168A 2006-02-15 2007-02-15 Medical devices and coatings with non-leaching antimicrobial peptides Abandoned CA2655168A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US77405006P 2006-02-15 2006-02-15
US60/774,050 2006-02-15
US11/561,266 2006-11-17
US11/561,266 US7739055B2 (en) 2005-11-17 2006-11-17 Methods and systems for generating and evaluating peptides
US88557807P 2007-01-18 2007-01-18
US60/885,578 2007-01-18
PCT/US2007/004394 WO2007095393A2 (en) 2006-02-15 2007-02-15 Medical devices and coatings with non-leaching antimicrobial peptides

Publications (1)

Publication Number Publication Date
CA2655168A1 true CA2655168A1 (en) 2007-08-23

Family

ID=38372168

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002655168A Abandoned CA2655168A1 (en) 2006-02-15 2007-02-15 Medical devices and coatings with non-leaching antimicrobial peptides

Country Status (5)

Country Link
US (1) US20070254006A1 (enExample)
EP (1) EP1991245A2 (enExample)
JP (1) JP2009526862A (enExample)
CA (1) CA2655168A1 (enExample)
WO (1) WO2007095393A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118325376A (zh) * 2024-03-29 2024-07-12 泛领生物医学技术(苏州)有限公司 一种抗微生物涂层及其制备方法与应用

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060057180A1 (en) * 2004-02-20 2006-03-16 Ashutosh Chilkoti Tunable nonfouling surface of oligoethylene glycol
US7824691B2 (en) * 2005-04-04 2010-11-02 Centegen, Inc. Use of RIP in treating staphylococcus aureus infections
GB0624423D0 (en) * 2006-12-06 2007-01-17 Univ Brighton Biomaterials with Functionalised Surfaces
US20090155335A1 (en) * 2007-12-05 2009-06-18 Semprus Biosciences Corp. Non-leaching non-fouling antimicrobial coatings
WO2009075788A1 (en) * 2007-12-05 2009-06-18 Semprus Biociences Corporation Synthetic non-fouling amino acids
US8034396B2 (en) 2008-04-01 2011-10-11 Tyco Healthcare Group Lp Bioadhesive composition formed using click chemistry
WO2012068179A1 (en) * 2010-11-15 2012-05-24 Rutgers, The State University Of New Jersey Multifunctional biodegradable peg nanocarrier-based hydrogels for preventing hiv transmission
GB0808350D0 (en) * 2008-05-09 2008-06-18 Airbus Uk Ltd Self-cleaning surfaces
GB0818074D0 (en) 2008-10-02 2008-11-05 Lytix Biopharma As Treatment of biofilms
DE102008053892A1 (de) * 2008-10-30 2010-05-06 Fachhochschule Gelsenkirchen Medizinisches Implantat mit biofunktionalisierter Oberfläche
ES2432388T3 (es) * 2008-12-05 2013-12-03 Semprus Biosciences Corporation Composiciones antiincrustantes, antimicrobianas y antitrombogénicas de injerto desde la superficie
US8308699B2 (en) * 2008-12-05 2012-11-13 Semprus Biosciences Corp. Layered non-fouling, antimicrobial antithrombogenic coatings
CN102368910B (zh) 2009-02-03 2014-07-30 艾戈泰克创新股份有限公司 微量营养肥料及其制备方法和用途
US8648144B2 (en) 2009-02-21 2014-02-11 Sofradim Production Crosslinked fibers and method of making same by extrusion
EP2398524B1 (en) 2009-02-21 2017-07-12 Covidien LP Medical devices having activated surfaces
US8663689B2 (en) 2009-02-21 2014-03-04 Sofradim Production Functionalized adhesive medical gel
WO2010095052A2 (en) 2009-02-21 2010-08-26 Sofradim Production Compounds and medical devices activated with solvophobic linkers
EP2398850B1 (en) 2009-02-21 2018-08-22 Sofradim Production Medical devices with an activated coating
WO2010095055A1 (en) 2009-02-21 2010-08-26 Sofradim Production Crosslinked fibers and method of making same using uv radiation
US8968733B2 (en) 2009-02-21 2015-03-03 Sofradim Production Functionalized surgical adhesives
US8512728B2 (en) 2009-02-21 2013-08-20 Sofradim Production Method of forming a medical device on biological tissue
AU2010215931A1 (en) 2009-02-21 2011-10-13 Covidien Lp Medical devices having activated surfaces
US8877170B2 (en) 2009-02-21 2014-11-04 Sofradim Production Medical device with inflammatory response-reducing coating
EP2398845B1 (en) 2009-02-21 2017-12-13 Sofradim Production Amphiphilic compounds and self-assembling compositions made therefrom
WO2010095053A2 (en) 2009-02-21 2010-08-26 Sofradim Production Apparatus and method of reaching polymers by exposure to uv radiation to produce injectable medical devices
US8535477B2 (en) 2009-02-21 2013-09-17 Sofradim Production Medical devices incorporating functional adhesives
AU2010215194A1 (en) 2009-02-21 2011-10-13 Sofradim Production Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices
US9181137B2 (en) 2009-03-20 2015-11-10 Agtec Innovations, Inc. Micronutrient fertilizers and methods of making and using the same
US8505743B2 (en) * 2009-04-08 2013-08-13 Michigan Molecular Institute Surface modification of polyamide reverse osmosis membranes
US9175036B2 (en) * 2009-12-07 2015-11-03 Ben-Gurion Unversity Of The Negev Research And Development Authority Antimicrobial water treatment membranes and production thereof
EP2550031B1 (en) 2010-03-25 2015-08-19 Sofradim Production Medical devices incorporating functional adhesives
AU2011231246B2 (en) 2010-03-25 2015-05-21 Sofradim Production Surgical fasteners and methods for sealing wounds
US10493793B2 (en) 2010-04-09 2019-12-03 Brown University Nanostructured surfaces
US8574660B2 (en) 2010-06-09 2013-11-05 Semprus Biosciences Corporation Articles having non-fouling surfaces and processes for preparing the same without altering bulk physical properties
SG186180A1 (en) * 2010-06-09 2013-01-30 Semprus Biosciences Corp Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
EP2579904A4 (en) 2010-06-09 2015-12-02 Semprus Biosciences Corp NON-CROPPED ANTIMICROBIAL ANTITHROMBOGENIC GRAFT COMPOSITIONS
AU2011276443A1 (en) 2010-06-29 2013-01-31 Covidien Lp Microwave-powered reactor and method for in situ forming implants
US20130195949A1 (en) * 2010-06-29 2013-08-01 Waters Technologies Corporation Antimicrobial Layer For Chromatographic Containers
WO2012001532A2 (en) 2010-07-01 2012-01-05 Sofradim Production Medical device with predefined activated cellular integration
WO2012014080A2 (en) 2010-07-27 2012-02-02 Sofradim Production Polymeric fibers having tissue reactive members
US8999031B2 (en) 2010-08-10 2015-04-07 Agtec Innovations, Inc. Polyphosphate fertilizer combinations
WO2012020428A1 (en) 2010-08-10 2012-02-16 Chandrika Varadachari Phosphate fertilizers and methods of using the same
CN102462859A (zh) * 2010-11-18 2012-05-23 私立中原大学 皮肤伤口愈合材料及其制造方法
HK1199201A1 (en) * 2011-10-10 2015-06-26 BERECZ, Roland Antimicrobial peptides for treatment of infectious diseases
JP2015508425A (ja) 2011-12-14 2015-03-19 センプラス・バイオサイエンシーズ・コーポレイションSemprus Biosciences Corp. 表面改質したコンタクトレンズ
US8870372B2 (en) 2011-12-14 2014-10-28 Semprus Biosciences Corporation Silicone hydrogel contact lens modified using lanthanide or transition metal oxidants
CA2859047C (en) 2011-12-14 2017-03-21 Semprus Biosciences Corp. Redox processes for contact lens modification
JP2015500913A (ja) 2011-12-14 2015-01-08 センプラス・バイオサイエンシーズ・コーポレイションSemprus Biosciences Corp. 表面改質コンタクトレンズを作り出すための多段階式uv方法
WO2013115917A1 (en) 2011-12-14 2013-08-08 Semprus Biosciences Corp. Imbibing process for contact lens surface modification
US8545951B2 (en) * 2012-02-29 2013-10-01 Kimberly-Clark Worldwide, Inc. Endotracheal tubes and other polymer substrates including an anti-fouling treatment
EP2894980B1 (en) * 2012-09-12 2020-12-23 Biocant - Centro de Inovação em Biotecnologia Antimicrobial coating compositions
WO2014130844A1 (en) 2013-02-21 2014-08-28 The Regents Of The University Of California Universal scalable and cost-effective surface modifications
US9149036B1 (en) * 2013-06-06 2015-10-06 Lloyd Starks Method for applying a persistent antimicrobial film
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
FR3016128B1 (fr) * 2014-01-07 2018-03-23 Aptar France Sas Tete de distribution et d'application.
CN104189963B (zh) * 2014-05-13 2017-01-04 江苏沣沅医疗器械有限公司 降低可全降解镁合金血管支架降解速率的表面涂层制备方法
SG11201707398WA (en) 2015-03-12 2017-10-30 Mitsui Chemicals Inc Method for destroying exosomes, kit for destroying exosomes, and method for isolating exosomes derived from normal cells
KR101693749B1 (ko) 2015-04-06 2017-01-06 삼성전기주식회사 인덕터 소자 및 그 제조방법
WO2016196633A1 (en) * 2015-06-01 2016-12-08 William Marsh Rice University Surface coating method to improve implantable device biocompatibility
GB201512031D0 (en) * 2015-07-09 2015-08-19 Univ Birmingham Functionalized surface
KR101659697B1 (ko) * 2015-10-02 2016-09-23 경희대학교 산학협력단 의료용 임플란트 및 그의 제조방법
KR101732490B1 (ko) * 2016-01-07 2017-05-04 숙명여자대학교산학협력단 기상 분자층 증착법을 이용하여 제조된 외부자극에 의해 분해가 가능한 고분자 구조체 및 그 제조방법
JP7161776B2 (ja) 2016-12-01 2022-10-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア エネルギー供給デバイス及びその用途
SE541313C2 (en) 2017-10-13 2019-06-25 Amferia Ab Amphiphilic antimicrobial hydrogel
TW201930485A (zh) 2017-12-01 2019-08-01 美國加利福尼亞大學董事會 抗生物結垢塗層及其製備及使用方法
EP3610728A1 (en) * 2018-08-14 2020-02-19 EMPA Eidgenössische Materialprüfungs- und Forschungsanstalt Antimicrobial coatings
CN111686312B (zh) * 2019-03-12 2022-07-15 华东理工大学 一种医用材料表面抗菌修饰层的制备方法及应用
TWI755710B (zh) 2019-04-16 2022-02-21 中央研究院 塗覆抗微生物肽於生物材料之方法及藉此塗覆之生物材料
ES3017384T3 (en) 2019-06-05 2025-05-12 The Regents Of Univ Of California Biofouling resistant coatings and methods of making and using the same
US12016802B2 (en) 2019-10-22 2024-06-25 Aerobiotix. Llc Air treatment system for operating or patient rooms
CN110841107A (zh) * 2019-12-12 2020-02-28 中国科学院深圳先进技术研究院 植入性材料、制备方法、植入性医疗器械及组织工程支架
WO2021156877A1 (en) * 2020-02-09 2021-08-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Antimicrobial matrix and uses thereof for eliminating microorganisms
CN111995788B (zh) * 2020-04-26 2021-09-21 中国科学院长春应用化学研究所 一种具有细菌响应性的聚合物刷及其制备方法
GB202008980D0 (en) * 2020-06-12 2020-07-29 Amicoat As Medical devices and materials
GB202008978D0 (en) * 2020-06-12 2020-07-29 Amicoat As Antimicrobial formulation
CN112870434B (zh) * 2021-01-22 2023-03-24 江苏大学 一种杀菌/抑菌生物活性界面材料及其制备方法
CN114432489A (zh) * 2022-01-29 2022-05-06 阳光生物科技有限公司 在金属表面制备具有长效抗菌效果多肽涂层的方法
CN114949374B (zh) * 2022-05-24 2023-06-13 安徽大学 一种抗菌促成骨双功能钛金属骨科植入物及其制备方法
CN116617470A (zh) * 2023-06-01 2023-08-22 四川大学 一种用于治疗植入物细菌感染的抗菌涂层及方法
WO2025129192A1 (en) * 2023-12-15 2025-06-19 Cascade Biocatalysts, Inc Polymer brush compositions including chain-end-immobilized cofactors and methods for the production thereof

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US329344A (en) * 1885-10-27 Geobge d
US329360A (en) * 1885-10-27 Automatic fire-extinguisher
US4098728A (en) * 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
US4211227A (en) * 1978-07-03 1980-07-08 The Kendall Company Surgical sponge material
US4254107A (en) * 1979-11-27 1981-03-03 Merck & Co., Inc. Long-lasting agonists of enkephalin
US5258041A (en) * 1982-09-29 1993-11-02 Bio-Metric Systems, Inc. Method of biomolecule attachment to hydrophobic surfaces
US4534881A (en) * 1983-12-19 1985-08-13 University Of South Alabama Inhibition of inorganic or biological CaCO3 deposition by poly amino acid derivatives
US4636208A (en) * 1984-10-05 1987-01-13 Ewald Rath Surgical sponge
LU86987A1 (fr) * 1987-09-07 1989-04-06 Glaverbel Microbilles de verre a proprietes bacteriostatiques,procede de fabrication de telles microbilles
US5585353A (en) * 1990-02-02 1996-12-17 The Rockefeller University Antibiotic peptides containing D-amino acids
US5180375A (en) * 1991-05-02 1993-01-19 Feibus Miriam H Woven surgical drain and woven surgical sponge
US6441130B1 (en) * 1991-05-24 2002-08-27 Isis Pharmaceuticals, Inc. Linked peptide nucleic acids
WO1995000547A1 (en) * 1993-06-22 1995-01-05 E.I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
US5811151A (en) * 1996-05-31 1998-09-22 Medtronic, Inc. Method of modifying the surface of a medical device
FR2751882B1 (fr) * 1996-07-31 1998-10-02 Inst Curie Surfaces hyperbactericides
US6054504A (en) * 1997-12-31 2000-04-25 Hydromer, Inc. Biostatic coatings for the reduction and prevention of bacterial adhesion
US6140127A (en) * 1998-02-18 2000-10-31 Cordis Corporation Method of coating an intravascular stent with an endothelial cell adhesive five amino acid peptide
US6150459A (en) * 1998-04-13 2000-11-21 Massachusetts Institute Of Technology Comb polymers for regulating cell surface interactions
DE19841585A1 (de) * 1998-09-11 2000-03-16 Rheinmetall W & M Gmbh Waffenrohr mit einer im Bereich der Rohrmündung angeordneten Kollimatorhalterung
US6592814B2 (en) * 1998-10-02 2003-07-15 Johnson & Johnson Vision Care, Inc. Biomedical devices with antimicrobial coatings
WO2000063079A1 (en) * 1999-04-15 2000-10-26 Ultracell Medical Technologies Of Connecticut, Inc. Method for producing surgical sponge device and product thereof
ES2221850T3 (es) * 1999-06-24 2005-01-16 Abbott Vascular Devices Limited Stents expandibles con balon.
EP1301571A2 (en) * 2000-07-17 2003-04-16 President And Fellows of Harvard College Surfaces that resist the adsorption of biological species
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US8172395B2 (en) * 2002-12-03 2012-05-08 Novartis Ag Medical devices having antimicrobial coatings thereon
US7282214B2 (en) * 2002-12-19 2007-10-16 Johnson & Johnson Vision Care, Inc. Biomedical devices with antimicrobial coatings
WO2005019241A2 (en) * 2003-08-18 2005-03-03 E.I. Dupont De Nemours And Company Cationic antimicrobial peptides and compositions thereof
WO2005109158A2 (en) * 2004-05-05 2005-11-17 Massachusetts Institute Of Technology Methods and systems for generating peptides
US20070048249A1 (en) * 2005-08-24 2007-03-01 Purdue Research Foundation Hydrophilized bactericidal polymers
WO2007061850A2 (en) * 2005-11-17 2007-05-31 Massachusetts Institute Of Technology Methods and systems for generating and evaluating peptides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118325376A (zh) * 2024-03-29 2024-07-12 泛领生物医学技术(苏州)有限公司 一种抗微生物涂层及其制备方法与应用

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