JP2009521911A5 - - Google Patents

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JP2009521911A5
JP2009521911A5 JP2008547880A JP2008547880A JP2009521911A5 JP 2009521911 A5 JP2009521911 A5 JP 2009521911A5 JP 2008547880 A JP2008547880 A JP 2008547880A JP 2008547880 A JP2008547880 A JP 2008547880A JP 2009521911 A5 JP2009521911 A5 JP 2009521911A5
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variant
asp
protein
ser259asp
substitution
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JP2008547880A
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JP5175214B2 (ja
JP2009521911A (ja
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Priority claimed from PCT/EP2006/012301 external-priority patent/WO2007076933A1/en
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JP2008547880A 2005-12-30 2006-12-20 改良された安定性を有するインターロイキン−１２ｐ４０変種 Active JP5175214B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75538205P 2005-12-30 2005-12-30
US60/755,382 2005-12-30
PCT/EP2006/012301 WO2007076933A1 (en) 2005-12-30 2006-12-20 Interleukin-12p40 variants with improved stability

Publications (3)

Publication Number Publication Date
JP2009521911A JP2009521911A (ja) 2009-06-11
JP2009521911A5 true JP2009521911A5 (enExample) 2010-02-18
JP5175214B2 JP5175214B2 (ja) 2013-04-03

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JP2008547880A Active JP5175214B2 (ja) 2005-12-30 2006-12-20 改良された安定性を有するインターロイキン−１２ｐ４０変種

Country Status (18)

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US (3) US7872107B2 (enExample)
EP (1) EP1966238B1 (enExample)
JP (1) JP5175214B2 (enExample)
KR (1) KR101343682B1 (enExample)
CN (1) CN101351475B (enExample)
AT (1) ATE555125T1 (enExample)
AU (1) AU2006332138B2 (enExample)
BR (1) BRPI0620648B1 (enExample)
CA (1) CA2635618C (enExample)
CY (1) CY1112884T1 (enExample)
DK (1) DK1966238T3 (enExample)
EA (1) EA015338B1 (enExample)
ES (1) ES2384055T3 (enExample)
PL (1) PL1966238T3 (enExample)
PT (1) PT1966238E (enExample)
SI (1) SI1966238T1 (enExample)
WO (1) WO2007076933A1 (enExample)
ZA (1) ZA200806611B (enExample)

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CN108574635B (zh) * 2017-03-09 2021-06-22 华为技术有限公司 一种路由优先级配置方法、设备以及控制器
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EP4031654A4 (en) * 2019-09-20 2023-11-22 The University of North Carolina at Chapel Hill MODIFIED T CELLS AND METHOD FOR PRODUCING THEREOF
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US20230220031A1 (en) * 2020-04-17 2023-07-13 The Board Of Trustees Of The Leland Stanford Junior University Engineered il-12 and il-23 polypeptides and uses thereof
KR102799318B1 (ko) * 2020-08-11 2025-04-23 주식회사 카나프테라퓨틱스 Il-12 및 항-fap 항체를 포함하는 융합단백질 및 이의 용도
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EP4373862A1 (en) * 2021-07-19 2024-05-29 Chugai Seiyaku Kabushiki Kaisha Protease-mediated target specific cytokine delivery using fusion polypeptide
KR20240161081A (ko) * 2021-09-17 2024-11-12 비카라 테라퓨틱스 인크. Caix 표적화 il-12 융합 단백질 및 그의 사용 방법
JP2024539139A (ja) 2021-10-20 2024-10-28 シンセカイン インコーポレイテッド ヘテロ二量体ｆｃサイトカインおよびその使用
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WO2024086739A1 (en) 2022-10-20 2024-04-25 Synthekine, Inc. Methods and compositions of il12 muteins and il2 muteins
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CN101351475B (zh) 2005-12-30 2013-05-15 默克专利有限公司 具有提高的稳定性的白细胞介素12p40变体

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