JP2009521496A - ＴＧＦ−β結合組成物 - Google Patents
ＴＧＦ−β結合組成物 Download PDFInfo
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- JP2009521496A JP2009521496A JP2008547744A JP2008547744A JP2009521496A JP 2009521496 A JP2009521496 A JP 2009521496A JP 2008547744 A JP2008547744 A JP 2008547744A JP 2008547744 A JP2008547744 A JP 2008547744A JP 2009521496 A JP2009521496 A JP 2009521496A
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Cited By (4)
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| JP2014518064A (ja) * | 2011-06-03 | 2014-07-28 | ゾーマ テクノロジー リミテッド | ＴＧＦ−βに特異的な抗体 |
| KR20150132262A (ko) * | 2013-03-20 | 2015-11-25 | 젠자임 코포레이션 | 불완전 골형성증의 치료 방법 |
| WO2016024628A1 (ja) * | 2014-08-14 | 2016-02-18 | 学校法人東京医科大学 | 樹状細胞の抗癌免疫賦活能の促進方法およびその用途 |
| JP2025028981A (ja) * | 2017-01-20 | 2025-03-05 | ジェンザイム・コーポレーション | 骨標的抗体 |
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| KR101245983B1 (ko) * | 2004-03-31 | 2013-06-28 | 제넨테크, 인크. | 인간화 항-ｔｇｆ-베타 항체 |
| CA2632799A1 (en) * | 2005-12-23 | 2007-07-05 | Eli Lilly And Company | Tgf-beta binding compositions |
| US8350006B2 (en) * | 2008-10-24 | 2013-01-08 | Mead Johnson Nutrition Company | Methods for determining the bioactivity of TGF-β in a composition |
| US8859205B2 (en) * | 2009-01-08 | 2014-10-14 | Bio-Rad Laboratories, Inc. | Methods and compositions for improving efficiency of nucleic acids amplification reactions |
| US20120294868A1 (en) * | 2009-04-24 | 2012-11-22 | Edwards James R | Anti-tgf-beta induction of bone cell function and bone growth |
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| EP2822592B1 (en) | 2012-03-08 | 2018-08-15 | Ludwig Institute for Cancer Research Limited | Tgf- 1 specific antibodies and methods and uses thereof |
| AU2016206682B2 (en) | 2015-01-14 | 2021-11-11 | The Brigham And Women's Hospital, Inc. | Treatment of cancer with anti-LAP monoclonal antibodies |
| TWI733661B (zh) | 2015-03-04 | 2021-07-21 | 美商健臻公司 | 以高親合性、結合性及特異性結合轉化生長因子－β１的經修飾ＩｇＧ抗體 |
| TWI726870B (zh) | 2015-03-04 | 2021-05-11 | 美商健臻公司 | 具有高親和性、結合性及專一性之結合轉形生長因子-β１的ｓｃＦｖ-Ｆｃ二聚體 |
| EP3277716B1 (en) | 2015-04-03 | 2020-06-24 | XOMA Technology Ltd. | Treatment of cancer using inhibitors of tgf-beta and pd-1 |
| EP3307772B1 (en) | 2015-06-12 | 2020-09-09 | Ludwig Institute For Cancer Research Limited | Tgf-beta 3 specific antibodies and methods and uses thereof |
| AU2017268234A1 (en) | 2016-05-17 | 2018-12-13 | Genentech, Inc. | Stromal gene signatures for diagnosis and use in immunotherapy |
| GB201610044D0 (en) | 2016-06-08 | 2016-07-20 | Ucb Biopharma Sprl | Antibodies |
| EP3565839A4 (en) | 2017-01-05 | 2021-04-21 | Gensun Biopharma Inc. | Checkpoint regulator antagonists |
| WO2019090263A1 (en) | 2017-11-06 | 2019-05-09 | Genentech, Inc. | Diagnostic and therapeutic methods for cancer |
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| WO2020095104A1 (en) | 2018-11-05 | 2020-05-14 | Ludwig Institute For Cancer Research Ltd. | HUMANIZED AND VARIANT TGF-β3 SPECIFIC ANTIBODIES AND METHODS AND USES THEREOF |
| EP3877055A1 (en) | 2018-11-05 | 2021-09-15 | Ludwig Institute for Cancer Research Ltd | Humanized and variant tgf-beta1 specific antibodies and methods and uses thereof |
| EP3990116A1 (en) | 2019-06-28 | 2022-05-04 | Gensun Biopharma Inc. | ANTITUMOR ANTAGONIST CONSISTING OF A MUTATED TGFß1 - RII EXTRACELLULAR DOMAIN AND AN IMMUNOGLOBULIN SCAFFOLD |
| CA3152371A1 (en) | 2019-08-01 | 2021-02-04 | Vaccinex, Inc. | Combined inhibition of semaphorin-4d and tgf.beta. and compositions therefor |
| WO2021167703A1 (en) | 2020-02-19 | 2021-08-26 | Nammi Therapeutics, Inc. | Formulated and/or co-formulated liposome compositions containing tgfb antagonist prodrugs useful in the treatment of cancer and methods thereof |
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| WO2022109443A1 (en) * | 2020-11-23 | 2022-05-27 | The Regents Of The University Of Michigan | Single-chain antibody against flavivirus ns1 protein |
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| KR20250133913A (ko) * | 2023-01-09 | 2025-09-09 | 베이징 투오 지에 바이오파마수티컬 컴퍼니 리미티드 | TGFβ1 결합 분자, GARP-TGFβ1 결합 분자 및 이의 의학적 용도 |
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- 2006-12-20 CA CA002632799A patent/CA2632799A1/en not_active Abandoned
- 2006-12-20 US US12/096,383 patent/US7494651B2/en not_active Expired - Fee Related
- 2006-12-20 WO PCT/US2006/062397 patent/WO2007076391A1/en not_active Ceased
- 2006-12-20 AU AU2006330542A patent/AU2006330542B2/en not_active Ceased
- 2006-12-20 EP EP06840328A patent/EP1966243B1/en not_active Not-in-force
- 2006-12-20 CN CN2006800485519A patent/CN101346394B/zh not_active Expired - Fee Related
- 2006-12-20 AT AT06840328T patent/ATE545657T1/de active
- 2006-12-20 BR BRPI0620240-3A patent/BRPI0620240A2/pt not_active IP Right Cessation
- 2006-12-20 ES ES06840328T patent/ES2379194T3/es active Active
- 2006-12-20 JP JP2008547744A patent/JP2009521496A/ja not_active Ceased
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2009
- 2009-02-06 US US12/366,664 patent/US20090155285A1/en not_active Abandoned
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- 2010-01-26 US US12/693,722 patent/US7927593B2/en not_active Expired - Fee Related
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| WO2005097832A2 (en) * | 2004-03-31 | 2005-10-20 | Genentech, Inc. | Humanized anti-tgf-beta antibodies |
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| JP2021112204A (ja) * | 2011-06-03 | 2021-08-05 | ゾーマ テクノロジー リミテッド | ＴＧＦ−βに特異的な抗体 |
| JP2020014464A (ja) * | 2011-06-03 | 2020-01-30 | ゾーマ テクノロジー リミテッド | ＴＧＦ−βに特異的な抗体 |
| KR102577578B1 (ko) | 2011-06-03 | 2023-09-11 | 조마 테크놀로지 리미티드 | Tgf-베타에 특이적인 항체 |
| JP7179903B2 (ja) | 2011-06-03 | 2022-11-29 | ゾーマ テクノロジー リミテッド | ＴＧＦ－βに特異的な抗体 |
| JP2018172412A (ja) * | 2011-06-03 | 2018-11-08 | ゾーマ テクノロジー リミテッド | ＴＧＦ−βに特異的な抗体 |
| KR20220063297A (ko) * | 2011-06-03 | 2022-05-17 | 조마 테크놀로지 리미티드 | Tgf-베타에 특이적인 항체 |
| JP2014518064A (ja) * | 2011-06-03 | 2014-07-28 | ゾーマ テクノロジー リミテッド | ＴＧＦ−βに特異的な抗体 |
| JP7016113B2 (ja) | 2013-03-20 | 2022-02-04 | ジェンザイム・コーポレーション | 骨形成不全症の処置方法 |
| KR102257138B1 (ko) | 2013-03-20 | 2021-05-26 | 젠자임 코포레이션 | 불완전 골형성증의 치료 방법 |
| KR20150132262A (ko) * | 2013-03-20 | 2015-11-25 | 젠자임 코포레이션 | 불완전 골형성증의 치료 방법 |
| JP2020109110A (ja) * | 2013-03-20 | 2020-07-16 | ジェンザイム・コーポレーション | 骨形成不全症の処置方法 |
| JP2019089826A (ja) * | 2013-03-20 | 2019-06-13 | ジェンザイム・コーポレーション | 骨形成不全症の処置方法 |
| JP2016519093A (ja) * | 2013-03-20 | 2016-06-30 | ジェンザイム・コーポレーション | 骨形成不全症の処置方法 |
| WO2016024628A1 (ja) * | 2014-08-14 | 2016-02-18 | 学校法人東京医科大学 | 樹状細胞の抗癌免疫賦活能の促進方法およびその用途 |
| JP2025028981A (ja) * | 2017-01-20 | 2025-03-05 | ジェンザイム・コーポレーション | 骨標的抗体 |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE545657T1 (de) | 2012-03-15 |
| WO2007076391A9 (en) | 2008-08-28 |
| US20100136021A1 (en) | 2010-06-03 |
| AU2006330542B2 (en) | 2012-05-24 |
| WO2007076391A1 (en) | 2007-07-05 |
| US20090155285A1 (en) | 2009-06-18 |
| US7494651B2 (en) | 2009-02-24 |
| US7927593B2 (en) | 2011-04-19 |
| BRPI0620240A2 (pt) | 2011-11-08 |
| ES2379194T3 (es) | 2012-04-23 |
| EP1966243B1 (en) | 2012-02-15 |
| US20080292638A1 (en) | 2008-11-27 |
| AU2006330542A1 (en) | 2007-07-05 |
| EP1966243A1 (en) | 2008-09-10 |
| CN101346394B (zh) | 2012-07-25 |
| CA2632799A1 (en) | 2007-07-05 |
| CN101346394A (zh) | 2009-01-14 |
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