AU2006330542B2 - TGF-beta binding compositions - Google Patents
TGF-beta binding compositions Download PDFInfo
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- AU2006330542B2 AU2006330542B2 AU2006330542A AU2006330542A AU2006330542B2 AU 2006330542 B2 AU2006330542 B2 AU 2006330542B2 AU 2006330542 A AU2006330542 A AU 2006330542A AU 2006330542 A AU2006330542 A AU 2006330542A AU 2006330542 B2 AU2006330542 B2 AU 2006330542B2
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- tgf
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- sequence
- antigen
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- C07K—PEPTIDES
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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Applications Claiming Priority (3)
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| PCT/US2006/062397 WO2007076391A1 (en) | 2005-12-23 | 2006-12-20 | Tgf-beta binding compositions |
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| AU2006330542A1 AU2006330542A1 (en) | 2007-07-05 |
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| WO2005097832A2 (en) * | 2004-03-31 | 2005-10-20 | Genentech, Inc. | Humanized anti-tgf-beta antibodies |
| EP1966243B1 (en) * | 2005-12-23 | 2012-02-15 | Eli Lilly And Company | Tgf-beta binding antibodies |
| US8350006B2 (en) * | 2008-10-24 | 2013-01-08 | Mead Johnson Nutrition Company | Methods for determining the bioactivity of TGF-β in a composition |
| WO2010080910A1 (en) * | 2009-01-08 | 2010-07-15 | Bio-Rad Laboratories, Inc. | Methods and compositions for improving efficiency of nucleic acids amplification reactions |
| EP2421559B1 (en) | 2009-04-24 | 2016-07-20 | Vanderbilt University | Anti-tgf-beta induction of bone growth |
| CN116333113A (zh) * | 2011-06-03 | 2023-06-27 | 佐马技术有限公司 | 对TGF-β具有特异性的抗体 |
| DK2822592T3 (en) | 2012-03-08 | 2018-10-15 | Ludwig Institute For Cancer Res Limited | TGF-1-SPECIFIC ANTIBODIES AND PROCEDURES AND APPLICATIONS THEREOF |
| BR112014022200A2 (pt) | 2012-03-08 | 2019-09-24 | Selig Sealing Products Inc | membro de vedação de recipiente com compodnente de segurança protegido e aba de remoção |
| AU2014235933B2 (en) * | 2013-03-20 | 2019-01-24 | Baylor College Of Medicine | Methods for treating osteogenesis imperfecta |
| JPWO2016024628A1 (ja) * | 2014-08-14 | 2017-09-21 | 学校法人東京医科大学 | 樹状細胞の抗癌免疫賦活能の促進方法およびその用途 |
| CA2973978A1 (en) | 2015-01-14 | 2016-07-21 | The Brigham And Women's Hospital, Inc. | Treatment of cancer with anti-lap monoclonal antibodies |
| TWI733661B (zh) | 2015-03-04 | 2021-07-21 | 美商健臻公司 | 以高親合性、結合性及特異性結合轉化生長因子－β１的經修飾ＩｇＧ抗體 |
| TWI726870B (zh) | 2015-03-04 | 2021-05-11 | 美商健臻公司 | 具有高親和性、結合性及專一性之結合轉形生長因子-β１的ｓｃＦｖ-Ｆｃ二聚體 |
| WO2016161410A2 (en) | 2015-04-03 | 2016-10-06 | Xoma Technology Ltd. | Treatment of cancer using inhibitors of tgf-beta and pd-1 |
| WO2016201282A2 (en) | 2015-06-12 | 2016-12-15 | Ludwig Institute For Cancer Research Ltd | TGF-β3 SPECIFIC ANTIBODIES AND METHODS AND USES THEREOF |
| EP3458608B1 (en) | 2016-05-17 | 2025-07-23 | F. Hoffmann-La Roche AG | Stromal gene signatures for diagnosis and use in immunotherapy |
| GB201610044D0 (en) | 2016-06-08 | 2016-07-20 | Ucb Biopharma Sprl | Antibodies |
| EP3565839A4 (en) | 2017-01-05 | 2021-04-21 | Gensun Biopharma Inc. | Checkpoint regulator antagonists |
| TW202421659A (zh) * | 2017-01-20 | 2024-06-01 | 美商健臻公司 | 骨靶向抗體 |
| CA3077664A1 (en) | 2017-11-06 | 2019-05-09 | Genentech, Inc. | Diagnostic and therapeutic methods for cancer |
| EP3814381A4 (en) | 2018-06-29 | 2022-08-10 | Gensun Biopharma Inc. | TRI-SPECIFIC ANTAGONISTS |
| WO2020095113A1 (en) | 2018-11-05 | 2020-05-14 | Ludwig Institute For Cancer Research Ltd | Humanized and variant tgf-beta1 specific antibodies and methods and uses thereof |
| CA3118027A1 (en) | 2018-11-05 | 2020-05-14 | Ludwig Institute For Cancer Research Ltd. | Humanized and variant tgf-.beta.3 specific antibodies and methods and uses thereof |
| JP2022540571A (ja) | 2019-06-28 | 2022-09-16 | ゲンスン バイオファーマ、インコーポレーテッド | 変異したＴＧＦβ１－ＲＩＩ細胞外ドメインおよび免疫グロブリン足場で構成される抗腫瘍アンタゴニスト |
| US20210032322A1 (en) | 2019-08-01 | 2021-02-04 | Vaccinex, Inc. | Combined inhibition of semaphorin-4d and tgf-beta and compositions therefor |
| WO2021167703A1 (en) | 2020-02-19 | 2021-08-26 | Nammi Therapeutics, Inc. | Formulated and/or co-formulated liposome compositions containing tgfb antagonist prodrugs useful in the treatment of cancer and methods thereof |
| CN113563473A (zh) | 2020-04-29 | 2021-10-29 | 三生国健药业（上海）股份有限公司 | 四价双特异性抗体、其制备方法和用途 |
| WO2022109443A1 (en) * | 2020-11-23 | 2022-05-27 | The Regents Of The University Of Michigan | Single-chain antibody against flavivirus ns1 protein |
| WO2022115611A1 (en) | 2020-11-25 | 2022-06-02 | Catamaran Bio, Inc. | Cellular therapeutics engineered with signal modulators and methods of use thereof |
| CN112940119B (zh) * | 2021-04-26 | 2022-05-20 | 北京芳渟阳生生物科技有限公司 | 一种单克隆抗体及其与间充质干细胞外泌体的联合应用 |
| CN115707716A (zh) * | 2021-08-18 | 2023-02-21 | 丹生医药技术(上海)有限公司 | 一种TGF-β/VEGF双功能抗体融合蛋白 |
| WO2023080900A1 (en) | 2021-11-05 | 2023-05-11 | Genentech, Inc. | Methods and compositions for classifying and treating kidney cancer |
| EP4527857A1 (en) | 2022-05-17 | 2025-03-26 | Suzhou Transcenta Therapeutics Co., Ltd. | Bifunctional protein, and preparation thereof and use thereof |
| WO2024077095A1 (en) | 2022-10-05 | 2024-04-11 | Genentech, Inc. | Methods and compositions for classifying and treating bladder cancer |
| EP4599088A1 (en) | 2022-10-05 | 2025-08-13 | Genentech, Inc. | Methods and compositions for classifying and treating lung cancer |
| WO2024149237A1 (zh) * | 2023-01-09 | 2024-07-18 | 北京拓界生物医药科技有限公司 | TGFβ1结合分子、GARP-TGFβ1结合分子及其医药用途 |
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| WO2005097832A2 (en) * | 2004-03-31 | 2005-10-20 | Genentech, Inc. | Humanized anti-tgf-beta antibodies |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571714A (en) | 1988-12-22 | 1996-11-05 | Celtrix Pharmaceuticals, Inc. | Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use |
| EP1646655A2 (en) * | 2003-07-09 | 2006-04-19 | Eli Lilly And Company | Tgf-beta1 ligands |
| EP1966243B1 (en) * | 2005-12-23 | 2012-02-15 | Eli Lilly And Company | Tgf-beta binding antibodies |
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2006
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- 2006-12-20 AU AU2006330542A patent/AU2006330542B2/en not_active Ceased
- 2006-12-20 JP JP2008547744A patent/JP2009521496A/ja not_active Ceased
- 2006-12-20 CA CA002632799A patent/CA2632799A1/en not_active Abandoned
- 2006-12-20 ES ES06840328T patent/ES2379194T3/es active Active
- 2006-12-20 BR BRPI0620240-3A patent/BRPI0620240A2/pt not_active IP Right Cessation
- 2006-12-20 CN CN2006800485519A patent/CN101346394B/zh not_active Expired - Fee Related
- 2006-12-20 WO PCT/US2006/062397 patent/WO2007076391A1/en not_active Ceased
- 2006-12-20 US US12/096,383 patent/US7494651B2/en not_active Expired - Fee Related
- 2006-12-20 AT AT06840328T patent/ATE545657T1/de active
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2009
- 2009-02-06 US US12/366,664 patent/US20090155285A1/en not_active Abandoned
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2010
- 2010-01-26 US US12/693,722 patent/US7927593B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005097832A2 (en) * | 2004-03-31 | 2005-10-20 | Genentech, Inc. | Humanized anti-tgf-beta antibodies |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100136021A1 (en) | 2010-06-03 |
| WO2007076391A9 (en) | 2008-08-28 |
| CA2632799A1 (en) | 2007-07-05 |
| CN101346394B (zh) | 2012-07-25 |
| WO2007076391A1 (en) | 2007-07-05 |
| ATE545657T1 (de) | 2012-03-15 |
| CN101346394A (zh) | 2009-01-14 |
| US20090155285A1 (en) | 2009-06-18 |
| US7494651B2 (en) | 2009-02-24 |
| BRPI0620240A2 (pt) | 2011-11-08 |
| ES2379194T3 (es) | 2012-04-23 |
| US7927593B2 (en) | 2011-04-19 |
| US20080292638A1 (en) | 2008-11-27 |
| EP1966243A1 (en) | 2008-09-10 |
| EP1966243B1 (en) | 2012-02-15 |
| AU2006330542A1 (en) | 2007-07-05 |
| JP2009521496A (ja) | 2009-06-04 |
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