JP2009519227A5 - - Google Patents

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Publication number
JP2009519227A5
JP2009519227A5 JP2008541450A JP2008541450A JP2009519227A5 JP 2009519227 A5 JP2009519227 A5 JP 2009519227A5 JP 2008541450 A JP2008541450 A JP 2008541450A JP 2008541450 A JP2008541450 A JP 2008541450A JP 2009519227 A5 JP2009519227 A5 JP 2009519227A5
Authority
JP
Japan
Prior art keywords
group
halogens
benzoylamino
yloxymethyl
biphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008541450A
Other languages
English (en)
Japanese (ja)
Other versions
JP5100657B2 (ja
JP2009519227A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/060769 external-priority patent/WO2007114855A2/en
Publication of JP2009519227A publication Critical patent/JP2009519227A/ja
Publication of JP2009519227A5 publication Critical patent/JP2009519227A5/ja
Application granted granted Critical
Publication of JP5100657B2 publication Critical patent/JP5100657B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008541450A 2005-11-18 2006-11-10 グルカゴン受容体アンタゴニストおよびその製造及び治療用途 Expired - Fee Related JP5100657B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73797905P 2005-11-18 2005-11-18
US60/737,979 2005-11-18
PCT/US2006/060769 WO2007114855A2 (en) 2005-11-18 2006-11-10 Glucagon receptor antagonists, preparation and therapeutic uses

Publications (3)

Publication Number Publication Date
JP2009519227A JP2009519227A (ja) 2009-05-14
JP2009519227A5 true JP2009519227A5 (enExample) 2009-12-10
JP5100657B2 JP5100657B2 (ja) 2012-12-19

Family

ID=38470878

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008541450A Expired - Fee Related JP5100657B2 (ja) 2005-11-18 2006-11-10 グルカゴン受容体アンタゴニストおよびその製造及び治療用途

Country Status (12)

Country Link
US (1) US8076374B2 (enExample)
JP (1) JP5100657B2 (enExample)
CN (1) CN101309894B (enExample)
AT (1) ATE473961T1 (enExample)
AU (1) AU2006341392B2 (enExample)
BR (1) BRPI0618484A2 (enExample)
CA (1) CA2629321C (enExample)
DE (1) DE602006015509D1 (enExample)
DK (1) DK1951659T3 (enExample)
ES (1) ES2346246T3 (enExample)
PT (1) PT1951659E (enExample)
WO (1) WO2007114855A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1758853E (pt) * 2004-06-14 2010-03-02 Lilly Co Eli Antagonistas do receptor de glucagon, sua preparação e usos terapêuticos
MX2009008534A (es) 2007-02-09 2009-11-23 Metabasis Therapeutics Inc Antagonistas novedosos del receptor de glucagon.
EP2799428B1 (en) 2008-08-13 2016-11-16 Metabasis Therapeutics, Inc. Glucagon antagonists
US8361959B2 (en) 2008-10-03 2013-01-29 Merck Sharp & Dohme Corp. Spiro-imidazolone derivatives as glucagon receptor antagonists
EP2480077B1 (en) 2009-09-22 2015-02-18 Merck Sharp & Dohme Corp. Pyrrolidines as glucagon receptor antagonists, compositions, and methods for their use
AU2011346670B2 (en) 2010-12-23 2015-05-07 Pfizer Inc. Glucagon receptor modulators
PH12013501557A1 (en) 2011-02-08 2019-06-03 Pfizer Glucagon receptor modulator
RU2013157388A (ru) * 2011-07-22 2015-08-27 Пфайзер Инк. Хинолинильные модуляторы глюкагонового рецептора
EP3065736B1 (en) 2013-11-04 2018-11-14 Merck Sharp & Dohme Corp. Glucagon receptor antagonist compounds, compositions thereof, and methods of use
WO2015191900A1 (en) 2014-06-12 2015-12-17 Ligand Pharmaceuticals, Inc. Glucagon antagonists
WO2016065139A1 (en) 2014-10-24 2016-04-28 Fl Therapeutics Llc 3-substituted piperidine-2, 6-diones and non-covalent complexes with albumin
JP2021513564A (ja) 2018-02-13 2021-05-27 リガンド・ファーマシューティカルズ・インコーポレイテッド グルカゴン受容体拮抗薬
CN110143935B (zh) * 2019-06-03 2022-09-30 华侨大学 一种2，5-二取代呋喃衍生物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420557D0 (en) 1994-10-12 1994-11-30 Zeneca Ltd Aromatic compounds
NL1004346C2 (nl) 1996-10-23 1998-04-24 Dsm Nv Werkwijze voor het scheiden van een mengsel van enantiomeren in een geschikt oplosmiddel.
AU2002365622A1 (en) 2001-12-03 2003-06-17 Novo Nordisk A/S Novel glucagon antagonists
JP2006500325A (ja) 2002-06-27 2006-01-05 ノボ　ノルディスク　アクティーゼルスカブ 新規なグルカゴンアンタゴニスト
WO2004056763A2 (en) * 2002-12-20 2004-07-08 Novo Nordisk A/S Novel glucagon antagonists
WO2004063147A1 (en) * 2003-01-10 2004-07-29 Novo Nordisk A/S Salts and solvates of glucagon antagonists
WO2005102067A1 (en) 2004-04-26 2005-11-03 Ipn Ip B.V. Packaged flowable ice product, such as a milk shake

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